• Asian Pacific Journal of Cancer Prevention
• /
• 제15권8호
• /
• pp.3503-3505
• /
• 2014

Background: Interleukin-33 (IL-33) has recently been implicated in tumor development. Methods: Data was obtained from PubMed, EMBASE, Clinical trial, Cochrane Library, Web of Science, CNKI and Wanfang databases. After quality assessment and data extraction, a meta-analysis was performed using Review Manager 5.2 software. Results: There were eight documents included in this meta-analysis. The results showed IL33 levels to be higher in tumor patients than that in health people, but no correlations tumor stage, metastasis and survival time of tumor patients were evident. Conclusion: IL33 may be useful as an alarm factor in tumor detection and prognosis.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권3호
• /
• pp.853-857
• /
• 2015

Background: Gastric cancer is the most common cancer in the Iranian population. The aim of this study was to determine the effect of clinicopathological factors on prognosis by meta-analysis. Materials and Methods: A literature search was conducted using MEDLINE, EMBASE and Cochrane library and extensive literature search using the Persian databases until February 2011. Prospective follow up studies with multivariate analysis of overall survival of the patients with gastric cancer were included in this review. The data were analyzed by CMA.2. Publication bias are checked by funnel plot and data are shown as Forest plots. Results: From a total of 63 articles, 14 retrospective studies which examined 5 prognostic factors and involving 10,500 patients were included. Tumor size (>35mm) was the main significant factor predicting an unfavorable prognosis for the patients with gastric cancer (RR=1.829, p<0.001) followed by presence of distant metastases (RR=1.607, p<0.001), poor differentiation (RR=1.408, p<0.001) and male sex (RR=1.194, p<0.001). Lymph node metastases (RR=1.058, p=0.698) and moderate differentiation (RR=0.836, p=0.043) were not statistically significant as prognostic factors. Conclusions: This meta-analysis suggests that tumor size>35mm, poor differentiation, presence of distant metastasis and male gender are strongly associated with a poor prognosis in Iranian patients with gastric cancer.

• Journal of the Korean Data and Information Science Society
• /
• 제22권4호
• /
• pp.717-726
• /
• 2011

본 연구는 메타분석을 이용하여 녹차를 투여한 당뇨 유발 쥐들의 체중과 혈액 내 혈당량, 총 콜레스테롤, 중성지방, 고농도지단백 콜레스테롤의 평균비교를 통해 녹차의 항-당뇨 효과에 대해 알아보고자 한다. 헤지의 표준화된 평균차에서 고정효과모형을 적용한 결과 체중은 통계적으로 유의한 증가를 보였으며, 혈액 내 혈당량과 중성지방은 통계적으로 유의한 감소를 보였다. 동질성 검정을 통해 이질성을 보인 모든 변수에 대해 랜덤효과모형을 적용시킨 결과 체중은 유의한 증가를 보였으며, 혈액 내 혈당량은 유의한 감소를 보였다. 또한 녹차의 투여기간이 변수에 영향을 미치는지 알아보기 위해 메타회귀분석을 실시한 결과 모든 변수에 대해 녹차의 투여기간이 유의하지 않았다.

• 한국정보과학회논문지:데이타베이스
• /
• 제29권2호
• /
• pp.148-157
• /
• 2002

메타 검색 엔진에서 캐쉬의 사용은 사용자의 응답시간을 향상시킬 수 있다. 본 논문에서는 메타 검색 엔진의 구조와 동작을 보이고, 메타 검색 엔진을 위한 인기도 기반의 새로운 캐쉬 대체 방법을 제안한다. 인기도는 사용자들이 검색 엔진에 요청한 단어들의 출현 빈도수를 정규화한 값으로, 캐쉬 대체를 위한 기준치로 이용된다. 본 논문에서는 인기 검색어 수집 방법, 인기도 산출방법을 기술하고, 인기도를 기반으로 하는 새로운 알고리즘을 제안한다. 또한 실제 사용자가 검색 엔진에 입력한 자료를 바탕으로, 전통적인 캐쉬 대체 기법인 LRU, LFU 알고리즘과 제안된 알고리즘을 성능 평가하였다. 본 성능 평가에서는 제안된 알고리즘이 대다수의 경우 우수한 성능을 나타내었다.

• 한국콘텐츠학회논문지
• /
• 제6권6호
• /
• pp.42-49
• /
• 2006

XML이 인터넷에서 정보전송을 위한 메타언어의 표현방법으로 급속하게 이용되고 있다. 아울러 XML 스키마는 XML 데이터의 다양한 유형을 표현하는데 사용하는 빈도수가 늘고 있다. 본 논문에서는 UML을 이용한 XML 스키마의 simpleType형 메타모델에 대한 설계를 하였다. 그러나 XML 스키마의 구조가 복잡하고 다양한 데이터의 유형을 지원하기 때문에 UML에서 나타내고 있는 모델의 속성에 대한 사용자의 이해와 적용에 어려운 부분이 많이 발생하는 것을 알 수 있다. 이를 해결하는 방법으로 본 연구에서는 OCL의 기능을 적용하여 XML 스키마 메타모델에서 구조적인 표현을 명확하게 명시할 수 있도록 하였으며, 아울러 이를 바탕으로 컴파일단계에서 어휘분석과 구문분석을 위한 파스트리와 토큰생성에 대한 구체적인 설계방법을 제시하였다.

• 근관절건강학회지
• /
• 제26권3호
• /
• pp.155-166
• /
• 2019

Purpose: This study was a meta-analysis of the effects of self-management on pain in patients with osteoarthritis. Methods: Randomized controlled trials were identified by searching PubMed, EMBASE, CINAHL, Ovid-MEDLINE and Korean database using key words, 'self-management', 'osteoarthritis' and 'pain'. Data were analyzed using the R version program. Results: Twenty nine studies met the inclusion criteria with a total of 5,998 participants. There were significant differences in overall effects of self-management (SMD -0.53, 95% CI -0.77~-0.29, p<.001). Conclusion: The results of the study show that self-management was effective in reducing pain in patients with osteoarthritis. As a result, it should be used as basic data when using self-management for patients with osteoarthritis.

• 한국인터넷방송통신학회논문지
• /
• 제21권5호
• /
• pp.127-134
• /
• 2021

최근 빅데이터 산업의 확대로 고품질의 데이터를 확보하는 것이 중요한 이슈로 떠오르고 있다. 고품질의 데이터를 확보하기 위해서는 데이터에 품질에 대한 정확한 평가가 선행되어야 한다. 데이터의 품질은 데이터에 대한 통계와 같은 메타정보를 통해 평가할 수 있는데 이러한 메타정보를 자동으로 추출하는 기능을 데이터 프로파일링이라고 하다. 지금까지 데이터 프로파일링 소프트웨어는 기존의 데이터 품질 또는 시각화 관련 소프트웨어의 부품이나 추가적인 서비스로 제공되는 것이 일반적이었다. 따라서 프로파일링이 요구되는 다양한 환경에서 직접적으로 사용하기에는 적합하지 않았다. 본 논문에서는 이를 해결하기 위해 마이크로 서비스 아키텍처를 적용하여 다양한 환경에서 서비스가 가능한 데이터 프로파일링 소프트웨어의 개발 결과를 제시한다. 개발된 데이터 프로파일러는 restful API를 통해 데이터의 메타정보에 대한 요청과 응답을 제공하여 사용하기 쉬운 서비스를 제공한다. 또한, 특정 환경에 종속되지 않고 다양한 빅데이터 플랫폼이나 데이터 분석 도구들과 원활한 연계가 가능하다는 장점이 있다.

• 대한간호학회지
• /
• 제46권4호
• /
• pp.475-489
• /
• 2016

Purpose: This study was a systematic review and meta-analysis designed to investigate the effects of stimulation-oriented interventions for behavioral problems among people with dementia. Methods: Based on the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA), a literature search was conducted using seven electronic databases, gray literature, and other sources. Methodological quality was assessed using the Scottish Intercollegiate Guidelines Network (SIGN) for randomized controlled trials (RCTs). Data were analyzed using R with the 'meta' package and the Comprehensive Meta-Analysis (CMA 2.0) program. Results: Sixteen studies were included for meta-analysis to investigate the effect of stimulation-oriented interventions. The quality of individual studies was rated as '++' for eight studies and '+' for the rest. The effect sizes were analyzed according to three subgroups of interventions (light, music, and others); Hedges' g=0.04 (95% CI: -0.38~0.46), -0.23 (95% CI: -0.56~0.10), -0.34 (95% CI: -0.34~0.00), respectively. To explore the possible causes of heterogeneity ($I^2=62.8%$), meta-regression was conducted with covariates of sample size, number of sessions, and length of session (time). No moderating effects were found for sample size or number of sessions, but session time showed a significant effect (Z=1.96, 95% CI: 0.00~0.01). Finally, a funnel plot along with Egger's regression test was performed to check for publication bias, but no significant bias was detected. Conclusion: Based on these findings, stimulation-oriented interventions seem to have a small effect for behavioral problems among people with dementia. Further research is needed to identify optimum time of the interventions for behavioral problems among dementia pateints.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권23호
• /
• pp.10175-10179
• /
• 2015

Background: The association between the RTEL1 rs6010620 single nucleotide polymorphism (SNP) and glioma risk has been extensively studied. However, the results remain inconclusive. To further examine this association, we performed a meta-analysis. Materials and Methods: A computerized search of the PubMed and Embase databases for publications regarding the RTEL1 rs6010620 polymorphism and glioma cancer risk was performed. Genotype data were analyzed in a meta-analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association. Sensitivity analyses, tests of heterogeneity, cumulative meta-analyses, and assessments of bias were performed in our meta-analysis. Results: Our meta-analysis confirmed that risk with allele A is lower than with allele G for glioma. The A allele of rs6010620 in RTEL1 decreased the risk of developing glioma in the 12 case-control studies for all genetic models: the allele model (OR=0.752, 95%CI: 0.715-0.792), the dominant model (OR=0.729, 95%CI: 0.685-0.776), the recessive model (OR=0.647, 95%CI: 0.569-0.734), the homozygote comparison (OR=0.528, 95%CI: 0.456-0.612), and the heterozygote comparison (OR=0.761, 95%CI: 0.713-0.812). Conclusions: In all genetic models, the association between the RTEL1 rs6010620 polymorphism and glioma risk was significant. This meta-analysis suggests that the RTEL1 rs6010620 polymorphism may be a risk factor for glioma. Further functional studies evaluating this polymorphism and glioma risk are warranted.

• 지역사회간호학회지
• /
• 제18권1호
• /
• pp.146-155
• /
• 2007

Purpose: This study was performed to examine the degree of meta cognition, critical thinking and self-efficacy and to identify correlations among the meta cognition, critical thinking, and self-efficacy of nursing students studying through PBL. Method: The subjects were 140 nursing students who had studied through PBL over three terms at C College. Data were collected from August to September, 2005 using a structured questionnaire and analyzed using SPSS 10.0. Results: The mean score of meta cognition was 40.14 (SD=6.02), critical thinking was 181.46 (SD=14.49), and self-efficacy was 942.93 (SD=167.05). There was a statistically significant positive correlation between meta cognition and self-efficacy and age. Also, meta cognition had a positive correlation with appropriateness to nursing and interest in nursing knowledge, and critical thinking had a positive correlation with appropriateness to nursing, interest in nursing knowledge, interest in lab on campus and interest in clinical practicum. There were statistically significant positive correlations among meta cognition, critical thinking and self-efficacy. Conclusion: Based on above results, further research should be done about many factors influencing nursing students' problem solving abilities for the development and application of many teaching methods for improving nursing students' meta cognition, critical thinking and self-efficacy.