• Journal of Information Science Theory and Practice
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• 제7권2호
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• pp.40-53
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• 2019

Although fake news has been present in human history at any time, nowadays, with social media, deceptive information has a stronger effect on society than before. This article answers two research questions, namely (1) Is the dissemination of fake news supported by machines through the automatic construction of filter bubbles, and (2) Are echo chambers of fake news manmade, and if yes, what are the information behavior patterns of those individuals reacting to fake news? We discuss the role of filter bubbles by analyzing social media's ranking and results' presentation algorithms. To understand the roles of individuals in the process of making and cultivating echo chambers, we empirically study the effects of fake news on the information behavior of the audience, while working with a case study, applying quantitative and qualitative content analysis of online comments and replies (on a blog and on Reddit). Indeed, we found hints on filter bubbles; however, they are fed by the users' information behavior and only amplify users' behavioral patterns. Reading fake news and eventually drafting a comment or a reply may be the result of users' selective exposure to information leading to a confirmation bias; i.e. users prefer news (including fake news) fitting their pre-existing opinions. However, it is not possible to explain all information behavior patterns following fake news with the theory of selective exposure, but with a variety of further individual cognitive structures, such as non-argumentative or off-topic behavior, denial, moral outrage, meta-comments, insults, satire, and creation of a new rumor.

• 한국임상약학회지
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• 제29권3호
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• pp.193-201
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• 2019

Background and Objective: Since the introduction of hospital pharmacy residency programs in 1983, hospital pharmacists in South Korea have been expected to expand their roles. However, their services and the outcomes have not been fully understood. In this study, we conducted a systematic review of Korean hospital pharmacist-provided interventions with regard to intervention type, intervention consequences, and target patient groups. Methods: A literature search of the following databases was performed: Embase, PubMed, Medline, KoreaMed, RISS, KMbase, KISS, NDSL, and KISTI. The search words were "hospital pharmacist", "clinical pharmacist", and "Korea". Articles reporting clinical or economic outcome measures that resulted from hospital pharmacist interventions were considered. Numeric measures for the acceptance rate of pharmacist recommendations were subjected to meta-analysis. Results: Of the 1,683 articles searched, 44 met the inclusion selection criteria. Most articles were published after 2000 (81.8%) and focused on clinical outcomes. Economic outcomes had been published since 2011. The interventions were classified as patient education, multidisciplinary team work, medication assessment, and guideline development. The outcome measures were physicians' prescription changes, clinical outcomes, patient adherence, economic outcomes, and quality of life. The acceptance rate was 80.5% (p < 0.005). Conclusion: Studies on pharmacist interventions have increased and showed increased patient health benefits and reduced medical costs at Korean hospital sites. Because pharmacists' professional competency would be recognized if the economic outcomes of their work were confirmed and justified, studies on their clinical performance should also include their economic impact.

• 대한한방소아과학회지
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• 제33권3호
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• pp.15-29
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• 2019

Objectives The purpose of this study is to investigate the clinical studies on the effect of herbal medicine in type 1 diabetes in children and to seek better approach of herbal medicine to treat type 1 diabetes in children. Methods This study researched randomized controlled trials through various databases in the world about herbal medicine treatments in type 1 diabetes in children. Results 10 out of 337 studies were selected and analyzed. All studies were conducted in China. All studies were using herbal medicines, as an adjunctive treatment to the main regimen. As a result, the integrated Chinese medicine and western medicine lowered FPG by -1.56 mmol/L and 2hPG by -1.94 mmol/L on average, respectively. The HbA1c also decreased by -1.11% in the treatment group compared to the control group. Total efficacy of the treatment was 1.21 times more effective in the treatment group than in the control group. Conclusions Based on the results of the studies, it seems that the herbal medicine for the treatment of type 1 diabetes in children will be effective as a combination with conventional medicines. Further research is needed to prove the findings of this observatoional studies.

• 한방재활의학과학회지
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• 제31권2호
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• pp.41-48
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• 2021

Objectives To determine the evidence of effectiveness and safety of extracorporeal shock wave therapy (ESWT) with meridian and acupoint theory for knee osteoarthritis. Methods By March 3, 2021, five foreign electronic databases and six Korean medical electronic databases were reviewed with the key words 'extracorporeal shock wave' and '(acupoint OR acupuncture point)'. This key words was set up to increase the sensitivity of the search. After the search, knee osteoarthritis study was selected based on the title and abstract and then included after full-texts were read. Results Five randomized controlled trials were eligible in our inclusion criteria. The meta-analysis of three studies showed positive results for the using ESWT with meridian and acupoint theory for knee osteoarthritis compared with the control group on efficancy rate, visual analog scale and lysholm knee score. but there remains a conundrum regarding the safety of ESWT in the treatment of knee osteoarthritis. Conclusions Most of studies showed ESWT with meridian and acupoint theory were statistically effective to knee osteoarthritis. However there are limitations that the number of selected studies was small, risk of bias was unclear. So use of ESWT with meridian and acupoint theory for knee arthritis has limited evidence compared to usual care.

• 한국콘텐츠학회논문지
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• 제21권10호
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• pp.630-644
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• 2021

본 연구는 인공호흡기 관련 폐렴 예방을 위한 근거기반 간호실무지침을 개발하고자 수행되었다. 한국보건의료연구원의 하이브리드 방법에 따라 근거기반 간호실무지침을 개발하고 유효성을 검증한 방법론적 연구이다. 주제와 핵심 질문은 문헌 검토와 전문가 인터뷰를 통해 도출하였고, 핵심 질문과 관련된 권고안은 체계적 검색과 선정에 의한 기존 가이드라인을 분석하여 수렴하였으며, 미해결 핵심 질문과 관련된 권고안은 체계적고찰과 메타 분석을 통해 새로 개발하였다. 개발된 권고안은 RAND에 의한 유효성 검증과 간호실무지침 초안은 AGREE II에 의한 방법론적 질평가를 수행하였다. 9개 범주의 44개 권고안으로 구성된 최종 간호실무지침의 임상타당성은 중환자실 간호사 122명을 대상으로 평가하였다. 최종 개발된 인공호흡기 관련 폐렴 예방을 위한 근거기반 간호실무지침은 방법론적 타당성과 내용타당도가 검증되었고 우리 간호실무 환경에 적합하여 중환자 간호실무의 질적 향상에 기여할 수 있을 것으로 기대된다.

• 대한한방내과학회지
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• 제41권6호
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• pp.1119-1140
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• 2020

Objective: The purpose of this study was to review Chinese clinical studies of the treatment of gastroesophageal reflux disease (GERD) with herbal medicine including Pinellia ternata. Methods: We searched the China National Knowledge Infrastructure (CNKI) database for clinical studies on herbal treatments including Pinellia ternata for GERD, from January 1st, 2015 to September 30th, 2019. We evaluated the risk of bias using Cochrane's risk of bias to confirm the quality of the 37 selected documents. Results: The 37 papers included high-dose and middle-dose Pinellia ternata groups. The outcome measures included treatment effectiveness rate, symptom comparisons, and endoscopy effectiveness rates or scores. In both groups, most studies showed significant improvement in the treatment group compared with the control group. The meta-analysis revealed a higher treatment effectiveness rate and a lower recurrence rate in the treatment group than in the control group. Conclusions: Comparing the treatment effect between the two groups was difficult due to the low quality of most studies. However, the results suggest that herbal remedies including Pinellia ternata showed statistically significant improvement in GERD compared to control groups.

• 한국임상약학회지
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• 제31권2호
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• pp.87-95
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• 2021

Background: Patients with chronic kidney disease (CKD) are at a high risk of stroke-related morbidity, mortality, and bleeding. However, the overall risk/benefit of anticoagulant therapy among patients with CKD remains unclear. Methods: The MEDLINE, EMBASE, and CENTRAL databases were comprehensively searched until July 31, 2020, to investigate the safety and efficacy of apixaban in patients with stage 4 or 5 CKD, as compared with warfarin. The primary outcome was an incidence of major bleeding. Secondary outcomes included composite bleeding (major, clinically relevant, and minor bleeding), venous thromboembolism (VTE), stroke, and death. Results: In total, seven studies consisting of 10,816 patients were included. Compared with warfarin, apixaban was associated with a reduced risk of major bleeding (OR 0.49, 95% CI 0.41-0.58). In terms of composite bleeding, apixaban tended to pose a significantly lower risk than warfarin (OR 0.51, 95% CI 0.37-0.71). There was no difference between apixaban and warfarin with respect to the risk of stroke or death (stroke: OR 1.23, 95% CI 0.49-3.12; death: OR 0.73, 95% CI 0.45-1.18). Conclusion: Among patients with stage 4 or 5 CKD, the use of apixaban was associated with a lower risk of bleeding compared to warfarin and was also found to pose no excess risk of thromboembolic events.

• 한국문헌정보학회지
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• 제55권2호
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• pp.227-261
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• 2021

본 연구의 목적은 학교도서관 평가 실태를 분석하여 학교도서관 평가의 발전 방향에 대한 시사점을 얻으려는 데에 있다. 이를 위해 교육부, 교육청 및 문화체육관광부를 중심으로 수행되는 학교도서관 관련 조사, 컨설팅 및 평가를 메타평가를 활용하여 분석하고, 사서교사를 대상으로 심층 면담 조사를 실시하였다. 분석 결과, 각 기관의 평가 중복, 국가의 학교도서관 발전계획의 반영 미비, 공모형 평가로 인한 참여율 저조, 교육 평가지표 미비 등의 문제점이 발견되었다. 이러한 문제를 해결하기 위한 학교도서관 운영평가의 개선방안은 법률에 평가 주체의 역할 명시, 국가의 도서관 발전계획의 반영, 기관 간 평가 네트워크 구축, 사례 공유 시스템 운영, 교육청의 조사 및 컨설팅과 전국 도서관 운영 평가의 연계 방안 마련을 제안하였다.

• 척추신경추나의학회지
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• 제16권1호
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• pp.13-23
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• 2021

Objectives To assess the effectiveness of chuna manual therapy for patients with total knee arthroplasty. Methods We searched 9 electronic databases(KISS, NDSL, RISS, OASIS, KMBASE, Cochrane Library, PubMed, CNKI, Wangfang data) using the keywords 'total knee arthroplasty OR total knee replacement' and 'tuina OR chuna' to identify RCTs that investigated the effectiveness of Chuna manual therapy after total knee arthroplasty. Results 23 RCTs were selected based on inclusion criteria. The systematic review showed positive effect of using chuna manual therapy after total knee arthroplasty. Conclusions 23 studies reported that chuna manual therapy had significant effects on total knee arthroplasty. However, many studies were exposed to probable high risk of bias. Also, all of the studies were published in one overseas country. Therefore, further research is required using well-designed RCTs to support the effectiveness of chuna manual therapy.

• 한국임상약학회지
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• 제31권1호
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• pp.61-78
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• 2021

Background and Objective: The use of potentially inappropriate medications (PIMs) increases the risk of negative health outcomes, including drug-related admissions. Tools for structured medication review have been developed to ensure optimal medication use and safety. Here, we aimed to evaluate medication use review (MUR) tools for community-dwelling older patients. Methods: We performed a systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement (PRISMA). We searched PubMed, Embase, and the Cochrane Library from 1991 to 2020, excluding tools that are specifically applied to hospitalized patients or nursing home residents. We identified the most common inappropriate medications, drug-disease interactions, drug-drug interactions and prescribing omissions presented among tools. Results: From among 9,788 identified reports screened, 60 met our inclusion criteria; finally, 27 were eligible for data analysis considering originality and up-to-dateness. Most tools presented explicit criteria (93%), and only one was specific to community-dwelling elderly. The most common PIM was tricyclic antidepressants. Use of diltiazem and verapamil in patients with heart failure and the combination of nonsteroidal anti-inflammatory analgesics and warfarin were the most frequent disease-specific PIM and drug-interaction, respectively. Conclusions: Although several medication review tools have been developed for older adults, specific guidelines for community-dwelling populations remain limited. Furthermore, the list of PIMs differed among available tools. In future, specific but integrating MUR tools need to be developed for clinical practice considering this population.