• Journal of Korean Society for Quality Management
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• v.40 no.1
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• pp.49-59
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• 2012

In computer simulation models the output from the computer code is often deterministic, i.e., running the code twice with the same values for the input variables would give the same output. It is discussed why the response surface method with polynomial approximation for the true response function is a good approximation to the computer experiments model. A sequential strategy to find the proper reduced quadratic polynomial model is illustrated with a case study in the military war game computer simulation model.

• Women's Health Nursing
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• v.19 no.1
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• pp.23-35
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• 2013

Purpose: This study was to analyze the effect size of complementary and alternative intervention studies in reference to dysmenorrhea and menstrual distress. Methods: In order to conduct a meta-analysis, a total of 393 studies were retrieved from the database. Twenty-eight studies that were published from March 2001 to February 2011 were selected. Results: Intervention studies included seven studies on aromatherapy, five on auriculotherapy, three on each Koryo-Sooji-Chim and moxibustion, two on each heat therapy and magnetic therapy and six on other therapy. The effect size of the intervention studies on dysmenorrhea and menstrual distress was greater than 0.48 for Koryo-Sooji-Chim, moxibustion, aromatherapy, auriculotherapy and other therapy. Conclusion: This study suggests that drug free therapy can reduce the levels of menstrual distress, despite the small number of intervention studies and randomized controlled trials.

• Proceedings of the Korea Concrete Institute Conference
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• 2010.05a
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• pp.263-264
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• 2010

In this study, respectively and furnaced kaolin at $900^{\circ}C$ was also manufactured into meta kaolin by air cooling and water cooling method. The chemical characteristic and mechanical properties of various type of blended cements contained above mentioned gypsum and meta kaolin materials analyzed and compared with those characteristics of cement matrix with silica fume. From the test, the cement mixed meta kaolin made in water cooling has more excellent quality than other material.

• Journal of muscle and joint health
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• v.26 no.3
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• pp.155-166
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• 2019

Purpose: This study was a meta-analysis of the effects of self-management on pain in patients with osteoarthritis. Methods: Randomized controlled trials were identified by searching PubMed, EMBASE, CINAHL, Ovid-MEDLINE and Korean database using key words, 'self-management', 'osteoarthritis' and 'pain'. Data were analyzed using the R version program. Results: Twenty nine studies met the inclusion criteria with a total of 5,998 participants. There were significant differences in overall effects of self-management (SMD -0.53, 95% CI -0.77~-0.29, p<.001). Conclusion: The results of the study show that self-management was effective in reducing pain in patients with osteoarthritis. As a result, it should be used as basic data when using self-management for patients with osteoarthritis.

• Child Health Nursing Research
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• v.23 no.4
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• pp.479-493
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• 2017

Purpose: This study was done to conduct a meta-analysis of articles describing randomized controlled trials which showed substantiated effects for home-based child abuse prevention programs for all parents. Methods: The articles regarding child abuse prevention programs for parents were investigated using the systematic review method. A literature search was conducted in PubMed, CINAHL, PsycINFO, Cochrane central library, Eric, and RISS on material published. Article searches and quality appraisal through RoB (Risk of Bias) yielded 14 records. Results: The total random effect size was 0.344 (Parents outcome, 0.333; Child outcome, 0.310; Environment, 0.275). The home based intervention for parents was effective for prevention of potential child abuse. Conclusion: This study supports the effectiveness of health care professional directing child abuse prevention programs for all parents whose children are in the early years of life including during the period of pregnancy.

• Journal of Information Technology Services
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• v.15 no.1
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• pp.299-319
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• 2016

This study first introduces platform services and their business models. On the basis of the concepts of business ecosystem, we present a framework for distinguishing types of the platform service business models. Two key characteristics of business ecosystems-ecosystem configuration and value production process-are employed as fundamental dimensions for constructing typology. In particular, we also present the notion of value ecosystem, where not a single platform provider but a federation of platforms constitutes a virtual platform and completes a service system. The value ecosystem represents two distinct types of platform service business models : meta-platform ecosystem and platform coalition ecosystem. They show different governance structure in the platform federation and service flows across the ecosystem. We present detailed analyses of these two value ecosystems focusing on relevant cases of e-payment FinTech : Apple Pay as an example of meta-platform and Kakao Pay for platform coalition. Our conceptual typology contributes to platforms' proper strategy formulation and presents policy implications to, for example, platform neutrality.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.14
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• pp.5551-5556
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• 2014

Background: The prognostic value of human epidermal growth factor receptor-2 (HER-2/neu) for survival of patients with colorectal cancer (CRC) is still ambiguous. We therefore performed a meta-analysis to evaluate its prognostic significance. Materials and Methods: We searched the MEDLINE and EMBASE databases for published literature investigating associations between HER-2/neu status and overall survival of patients with CRC. A meta-analysis was performed using a DerSimonian-Laird model and publication bias was investigated by Begg's and Egger's tests. Subgroup analysis was also conducted according to the study design type, study quality score, cut-off value for HER-2/neu overexpression, publication region, patient number and publication year. Results: A total of 17 eligible studies involving 2,347 patients were identified for this meta-analysis. The combined hazard ratio (HR) was 1.31 (95% confidence interval (CI): 0.96-1.79), suggesting that HER-2/neu overexpression was not significantly associated with overall survival of patients with CRC. However, subgroup analysis revealed that HER-2/neu overexpression had an unfavorable impact on survival when the analysis was restricted to subgroups of study quality score ${\leq}5 $(HR=1.56, 95%CI: 1.17-2.10), Asian patients (HR=1.74, 95%CI: 1.22-2.49), patient number ${\leq}106$ (HR=1.57, 95%CI: 1.01-2.44), publication year before 2003 (HR=1.59, 95%CI: 1.02-2.49), and prospectively designed study (HR=3.62, 95%CI: 1.42-9.24). The effect disappeared in subgroups of study quality scores > 5 (HR=0.69, 95%CI: 0.33-1.44), non Asian patients (HR=1.14, 95%CI: 0.77-1.70), patients' number > 106 (HR=1.07, 95%CI: 0.67-1.72), publication year after 2003 (HR=1.13, 95%CI: 0.76-1.69), and retrospectively designed study (HR=1.22, 95%CI: 0.89-1.67). Conclusions: Our meta-analysis suggests that HER-2/neu overexpression might not be a significantly prognostic indicator for patients with CRC. Further studies are required to confirm these results.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9085-9091
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• 2014

Background: Epidemiology studies have shown an inconclusive relationship between phytoestrogen intake and ovarian cancer risk and there have been no relevant meta-analyses directly regarding this topic. The purpose of the present meta-analysis was therefore to investigate any association between phytoestrogen intake and ovarian cancer in detail. Materials and Methods: We conducted a search of PubMed, EMBASE, EBSCO, the Cochrane Library, CNKI and Chinese Biomedical Database (up to April 2014) using common keywords for studies that focused on phytoestrogen and ovarian cancer risk. Study-specific risk estimates (RRs) were pooled using fixed effect or random-effect models. Results: Ten epidemiologic studies were finally included in the meta-analysis. The total results indicated higher phytoestrogen intake was associated with a reduced ovarian cancer risk (RR, 0.70; 95%CI: 0.56-0.87). The association was similar in sensitivity analysis. Meta regression analysis demonstrated sources and possibly types and regions as heterogeneous factors. Subgroup analysis of types, sources and regions showed that isoflavones (RR: 0.63; 95%CI: 0.46, 0.86), soy foods (RR: 0.51; 95%CI: 0.39, 0.68) and an Asian diet (RR: 0.48; 95%CI: 0.37, 0.63) intake could reduce the incidence of ovarian cancer. Conclusions: Our findings show possible protection by phytoestrogens against ovarian cancer. We emphasize specific phytoestrogens from soy foods, but not all could reduce the risk. The habit of plentiful phytoestrogen intake by Asians is worthy to recommendation. However, we still need additional larger well designed observational studies to fully characterize underlying associations.

• Journal of the Korea Convergence Society
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• v.11 no.2
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• pp.361-373
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• 2020

The purpose of this study was to meta-analyze the stress intervention program applied to patients with hemodialysis in Korea to confirm the effectiveness of the stress intervention program and to identify the characteristics and trends of the stress intervention method. A total of 10 studies were selected, and Quality Assessment tool was used MINORS and the data was analyzed using Comprehensive Meta Analysis Version 3.0 and Review manager version 5.3 The Quality Assessment score of studies was 21.2 points, and the effect size on the psychological stress was medium(g=-.72), and the effect size on cortisol of the physiological stress was also medium(g=-.52). Subgroup analysis showed that Music therapy and aromatherapy, individual providing, over 60 minutes per session and total of 10-20 times were more effectively reduced stress. Findings of this meta-analysis would be helpful for health professionals to provide more effective stress intervention program. Further randomized controlled trials of stress intervention program for patients with hemodialysis are more needed.

• Economic and Environmental Geology
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• v.14 no.2
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• pp.55-76
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• 1981

Southwestern contact zone of the Boeun granodiorite occurs near the thrust fault between the Ogcheon Group and Majeonri Limestone Formation. Ogcheon Group, metasediments composed of the Munjuri Formation, Changri Formation, and unconformably overlying Hwanggangri Formation, belongs to greenschist facies of regional metamorphism accompanied with deformation of two fold axes, $N10^{\circ}E$ and $N45-65^{\circ}E$ directions. Basic metamorphic rocks occurring in the Changri and Limestone Formations are the meta-basalts and meta-diabases of tholeiitic basalt series. The meta-basalts intruded in the Changri Formation as sills, whereas the meta-diabases in the Changri and Limestone Formations as stocks in appearance. They are considered to have emplaced before the formation of two fold axes and related with the thrust fault, based on the geologic setting of the area. The metamorphic facies are identified to be greenschist facies to epidote-amphibolite facies for the meta-basalt, and epidote-amphibolite facies for the meta-diabases. It is interpreted that such a variety of facies was related from the combination of earlier deuteric alteration and later regional metamorphism. The metasediments in southwestern contact zont of the Boeun granodiorite which is a product of later syntectonic intrusion of middle Jurassic in age, show pyroxene-hornfels facies near the contact and amphibole-horenfels facies away from the contact to the mineral zoning in the contact metamorphic aureole of the Limestone Formation, based on the paragenetic analysis of mineral assemblages. The Limestone in the area appears to be considerably $SiO_2-CaO-MgO-CO_2-H_2O$ can be adopted to evaluate equilibrium conditions of the mineral assemblages in each mineral zone. It is revealed that a temperature gradient was existed accross the contact aureole ranging from the higher igneous side to lower sedimentary side, whereas no clear trend of $XCO_2$ variation appears but high mole fraction. The tremolite diopside-quartz-calcite assemblages occurs in common through the most mineral zones of contact aureole that is in good agreement with the equivalent reaction curve which extends over a wide range of $T-XCO_2$ conditions.