• 성인간호학회지
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• 제28권1호
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• pp.116-126
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• 2016

Purpose: Lung cancer patients are often stigmatized since lung cancer is closely associated with smoking, which is a self-administered life style. The stigma of lung cancer has been examined in some qualitative studies; however, their findings were diverse and not yet synthesized. Therefore, this meta-synthesis study aimed to explore how lung cancer patients experience stigma. Methods: A meta-synthesis method, as suggested by Sandelowski and Barroso in 2007, was applied by aggregating the findings after an evaluation according to consolidated criteria for reporting qualitative research (COREQ). Results: By synthesizing the findings of the selected seven papers, a synthesized theme was emerged as "experiencing external and internal distances, which mandates authentic and consistent supports." The four sub-themes included 'experiencing some distance from the surrounded world,' 'experiencing self-made distance between the disease and oneself,' 'the disease experience causes social isolation and loneliness,' and 'there is lack of supportive care for myself.' Conclusion: Health care providers should be more attentive to supporting lung cancer patients by providing more effective advocacy programs that improve patients' quality of life.

• Journal of Gastric Cancer
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• 제23권3호
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• pp.428-450
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• 2023

This meta-analysis examined the surgical management of older patients (>80 years) with gastric cancer, who were often excluded from randomized controlled trials. We analyzed 23 retrospective cohort studies involving 18,372 patients and found that older patients had a higher in-hospital mortality rate (relative risk [RR], 3.23; 95% confidence interval [CI], 1.46-7.17; P<0.01) and more post-operative complications (RR, 1.36; 95% CI, 1.19-1.56; P<0.01) than did younger patients. However, the surgical complications were similar between the two groups. Older patients were more likely to undergo less extensive lymph node dissection and longer hospital stays. Although older patients had statistically significant post-operative medical complications, they were not deprived of surgery for gastric cancer. The comorbidities and potential risks of post-operative complications should be carefully evaluated in older patients, highlighting the importance of careful patient selection. Overall, this meta-analysis provides recommendations for the surgical management of older patients with gastric cancer. Careful patient selection and evaluation of comorbidities should be performed to minimize the risk of post-operative complications in older patients, while recognizing that they should not be deprived of surgery for gastric cancer.

• Journal of Gynecologic Oncology
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• 제29권6호
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• pp.98.1-98.13
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• 2018

Objective: We describe a systematic review and meta-analysis of the performance of ${18}F$-fluorodeoxyglucose ($^{18}F-FDG$) positron emission tomography/computed tomography (PET/CT) for detecting metastasis in ovarian cancer. Methods: MEDLINE and Embase were searched for diagnostic accuracy studies that used $^{18}F-FDG$ PET or PET/CT for pre-treatment staging, using surgical findings as the reference standard. Sensitivities and specificities were pooled and plotted in a hierarchic summary receiver operating characteristic plot. Potential causes of heterogeneity were explored through sensitivity analyses. Results: Eight studies with 594 patients were included. The overall pooled sensitivity and specificity for metastasis were 0.72 (95% confidence interval [CI]=0.61-0.81) and 0.93 (95% CI=0.85-0.97), respectively. There was considerable heterogeneity in sensitivity ($I^2=97.57%$) and specificity ($I^2=96.74%$). In sensitivity analyses, studies that used laparotomy as the reference standard showed significantly higher sensitivity and specificity (0.77; 95% CI=0.67-0.87 and 0.96; 95% CI=0.92-0.99, respectively) than those including diagnostic laparoscopy (0.62; 95% CI=0.46-0.77 and 0.84; 95% CI=0.69-0.99, respectively). Higher specificity was shown in studies that confirmed surgical findings by pathologic evaluation (0.95; 95% CI=0.90-0.99) than in a study without pathologic confirmation (0.69; 95% CI=0.24-1.00). Studies with a lower prevalence of the FDG-avid subtype showed higher specificity (0.97; 95% CI=0.94-1.00) than those with a greater prevalence (0.89; 95% CI=0.80-0.97). Conclusion: Pre-treatment $^{18}F-FDG$ PET/CT shows moderate sensitivity and high specificity for detecting metastasis in ovarian cancer. With its low false-positive rate, it can help select surgical approaches or alternative treatment options.

• 한국기계가공학회지
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• 제20권5호
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• pp.85-95
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• 2021

Structure design sensitivity was evaluated using the orthogonal array experimental method for passive-type deck support frame (DSF) developed for float-over installation of the offshore plant. Moreover, approximation characteristics were also reviewed based on various meta-models. The minimum weight design of the DSF is significantly important for securing both maneuvering performance and buoyancy of a ship equipped with the DSF and guaranteeing structural design safety. The performance strength of the passive type DSF was evaluated through structure analysis based on the finite element method. The thickness of main structure members was applied to design factors, and output responses were considered structure weight and strength performances. Quantitative effects on the output responses for each design factor were evaluated using the orthogonal array experimental method and analysis of variance. The optimum design case was also identified from the orthogonal array experiment results. Various meta-models, such as Chebyshev orthogonal polynomial, Kriging, response surface method, and radial basis function-based neural network, were generated from the orthogonal array experiment results. The results of the orthogonal array experiment were validated using the meta-modeling results. It was found that the radial basis function-based neural network among the meta-models could approximate the design space of the passive type DSF with the highest accuracy.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.52-54
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• 2021

인공 지능 시대가 도래함에 따라, 로봇 교육과 그 역량 강화에 대한 교육은 전 세계적으로 널리 적용되고 적용되었습니다. 본 연구의 목적 : 학생 교육 및 교육에서 AI 교육 로봇의 응용 효과를 체계적으로 평가; 본 연구의 방법 : 컴퓨터를 사용하여 "Web of Science", "CNKI", "ERIC", "IEEE"와 같은 검색 도구에서 관련 교육을 검색하십시오. 로봇 티칭과 전통적인 티칭의 효과에 대한 비교 연구 검색 시간은 2000 년 1 월부터 2020 년 1 월까지입니다. 포괄적인 MetaAnalysis 2.0을 메타 분석에 사용했습니다. 본 연구 결과 : 31 개의 유효한 연구 문헌에 대한 정량 분석과 메타 분석이 AI 교육 로봇에 미치는 영향에 대한 객관적인 평가 분석 결과 AI 교육 로봇이 학생 학습 효과에 미치는 효과는 0.465임 이는 교육용 로봇이 학생의 학습 효과에 어느 정도 긍정적인 영향을 미침을 나타냅니다. 이 연구의 결론 : 학생 교육 및 교육에서 AI 교육 로봇의 적용 효과는 전통적인 교육 방법보다 우수하며 학생 학습을보다 효과적으로 홍보 할 수 있습니다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권7호
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• pp.1773-1793
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• 2023

Automated machine learning, often referred to as "AutoML," is the process of automating the time-consuming and iterative procedures that are associated with the building of machine learning models. There have been significant contributions in this area across a number of different stages of accomplishing a data-mining task, including model selection, hyper-parameter optimization, and preprocessing method selection. Among them, preprocessing method selection is a relatively new and fast growing research area. The current work is focused on the recommendation of preprocessing methods, i.e., feature subset selection (FSS) algorithms. One limitation in the existing studies regarding FSS algorithm recommendation is the use of a single learner for meta-modeling, which restricts its capabilities in the metamodeling. Moreover, the meta-modeling in the existing studies is typically based on a single group of data characterization measures (DCMs). Nonetheless, there are a number of complementary DCM groups, and their combination will allow them to leverage their diversity, resulting in improved meta-modeling. This study aims to address these limitations by proposing an architecture for preprocess method selection that uses ensemble learning for meta-modeling, namely AutoFE-Sel. To evaluate the proposed method, we performed an extensive experimental evaluation involving 8 FSS algorithms, 3 groups of DCMs, and 125 datasets. Results show that the proposed method achieves better performance compared to three baseline methods. The proposed architecture can also be easily extended to other preprocessing method selections, e.g., noise-filter selection and imbalance handling method selection.

• 한국산학기술학회논문지
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• 제18권11호
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• pp.445-453
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• 2017

최근 정부 R&D 방향을 보면 정부출연연의 역할은 중장기, 대규모 신규사업발굴에 초점을 두고 있으며 출연연 자체적으로 연구기획에 많은 투자와 노력을 하고 있다. 하지만, 출연연 주요사업 연구기획에 철저한 준비가 되어야 함에도 기획 전문지식이 체계적으로 축적되지 않았으며 좋은 연구기획 본보기에 대한 요구가 지속적으로 이어져왔다. 이에 본 연구에서는 심도 있는 사전 검토 절차를 거치는 국가연구개발 예비타당성조사 사업 보고서를 본보기로 제안하고자 한다. 이를 위해 예비타당성조사의 계층구조와 세부평가항목을 고찰하고 주요사업 기획에 도움이 되는 세부평가항목들과 내용을 선별하고자 한다. 우선 현재 공개된 예비타당성조사 보고서 중에서 연구에 해당하는 대상을 선별하고, 보고서의 평가항목들 중에서 메타분석을 통해 출연연 주요사업 기획에 반영될 수 있는 12개 평가항목들을 선별하였다. 아울러, 전문가 회의를 거쳐 분석된 내용들에서 각 세부평가항목별 주요사업 기획관련 시사점을 도출하였다. 본 연구를 통해 주요사업 기획 연구자들에게 실무적으로 R&D 연구기획과 평가 향상에 기여할 것이라 기대한다.

• 대한한의학회지
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• 제24권2호
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• pp.47-58
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• 2003

The purpose of this study was to integrate the therapeutic effects of Oriental medicine for stroke in clinical research published in Korea from 1991 to 2000. In the preliminary study, clinical studies on Oriental medical therapy for stroke in Korea were collected. Since it was inadequate to integrate the results of the papers, qualitative meta-analysis was conducted on them. In age distribution of occurrence, the most frequent age was sixties followed by seventies, fifties, forties, and thirties. Sample size was minimum 42 persons, maximum 473 persons. Papers including single therapy were noted in 50.1 %. Among those, herbal medicine was noted in 30%, while acupuncture, physical treatment, and moxibustion was noted in 6.7%. Including more than two therapies were noted in 49.1 %, Among those, herbal medicine was noted in 80%, acupuncture in 20%, physical treatment in 13%, western and oriental medicine in 30%. Papers including control group were noted in 13% and description of scale for the evaluation of treatment effect was 80%. Papers including objectification of scales for the evaluation of therapeutic effects were noted in 26.7% and described follow-up period were noted in 13%. Papers including statistical analysis were noted in 26.7% and calculated p-value was noted in. 13.3%. Papers including design of longitudinal study were noted in 86.7%. Case-control studies were noted in 13.3%. Randomization and blinding were noted in each 0%. These results suggest that followings are required for the improvement of quality of clinical research in Oriental medicine; obvious description of treatment method, objectification of scales for the evaluation of therapeutic effects, adequate research design, randomization and blinding.

• 한국정보시스템학회지:정보시스템연구
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• 제16권4호
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• pp.131-155
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• 2007

The purpose of this thesis is to study on the philosophical analysis model and its methodological application of information systems research evaluation from critical realist perspective. Fist of all, I examine ontological epistemological methodological assertions of critical realism. Because the philosophy of critical realism is an opportunity for information systems study. I examine Dobson and Mutch's critical realist perspective on actors-structure model. I suggest a critical realist actors-praxis-structure model. This model provides the potential for a new approach to social investigations in its provision of an ontology for the analytical separation of structure and agency. Of most importance might be the incorporation of non-humans into the analysis of social interaction and of technology into the elaboration of structures. I also examine Tsoukas's critical realistic meta-theory of management. I suggest a critical realist IS management model. This model elucidate the nature of management and delineate the scope of applicability of various perspectives on management. The causal powers of management reside in the real domain and, taken together, their logics are contradictory, the effects of their contradictory composition are contingent upon prevailing contingencies. I analyze Carlsson's theory of design knowledge. His framework builds on that the aim of IS design science research is to develop practical knowledge for the design and realization of different classes of IS initiatives, where IS are viewed as socio-technical systems and not just IT artefacts. The framework proposes that the output of IS design science research is practical IS design knowledge in the form of field-tested and grounded technological rules. The IS design knowledge is developed through an IS design science research cycle. In conclusion, I think that IS actors-praxis-structure model, meta-theoretical IS management model, and IS design knowledge model according to critical realistic approach are very useful for IS research evaluation. Nevertheless, important problems are left not resolved.

• 농약과학회지
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• 제14권1호
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• pp.72-77
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• 2010

3차원적 정량적인 구조-활성관계(3D-QSARs: CoMFA 및 CoMSIA)에 기초하여 phytoene desaturase (PDS)에 대한 O-(2-phenoxy)ethyl-N-aralkylcarbamate 유도체(1-15)의 제초성 평가를 위한 R-phenoxy 치환기들의 구조적인 요건들을 정량적으로 검토하였다. CoMFA 1 모델의 예측성 및 상관성($r^2_{cv.}=0.753$ 및 $r^2_{ncv.}=0.964$)이 나머지 모델들보다 높았다. 최적화된 CoMFA 1 모델로부터 PDS 저해활성은 O-(2-phenoxy)ethyl-N-aralkylcarbamate 유도체들의 입체장(44.0%), 정전기장(36.3%) 및 소수성장(19.6%)에 의존적이었다. CoMFA 등고도 분석결과, phenoxy 고리상 meta-와 para-위치에는 입체적으로 큰 치환기, meta-위치는 음하전, para-위치의 바깥 부분에는 양하전, ortho- 및 para- phenoxy 고리 중앙의 바깥 부분에는 친수성 치환기가 그리고 meta-위치에 소수성 R-치환기가 각각 도입될 경우에 PDS에 대한 저해활성이 증가할 것으로 예측되었다.