• Title/Summary/Keyword: Memory function

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Spaced Retrieval Effects in Older Adults with Mild Alzheimer's Disease (경증 알츠하이머형 치매노인에 대한 시간차회상훈련의 효과)

  • Ban, Seon-Hwa;Jun, Seong-Sook
    • Korean Journal of Adult Nursing
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    • v.24 no.4
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    • pp.398-405
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    • 2012
  • Purpose: The purpose of this study was to develop spaced retrieval training as a nursing intervention for patients having an mild alzheimer's disease and to determine the effects of the program on their memory and cognitive function across training sessions. Methods: A non-equivalent control group pre test-post test design was used in this study. Participants were recruited from a local community: 14 patients were allocated into experimental group and 12 patients were allocated into control group. The experimental group was asked to participate in spaced retrieval training over 4 weeks, with seven times a week and 1 hour a session based. The study was conducted from June 20, 2011 to July 17, 2011. Data was analyzed with descriptive statistics, $x^2$-test and t-test using the SPSS/WIN 19.0 program. Results: After spaced retrieval training, the experimental group showed significant increases in scores for memory (t=12.40, p<.001) and cognitive function (t=7.69, p<.001) in comparison to the control group. Conclusion: Spaced retrieval training was effective in increasing cognitive function and memory of patients having mild alzheimer's disease. Therefore spaced retrieval training could be benefit the mild alzheimer's disease.

Nano-Floating Gate Memory Devices with Metal-Oxide Nanoparticles in Polyimide Dielectrics

  • Kim, Eun-Kyu;Lee, Dong-Uk;Kim, Seon-Pil;Lee, Tae-Hee;Koo, Hyun-Mo;Shin, Jin-Wook;Cho, Won-Ju;Kim, Young-Ho
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.8 no.1
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    • pp.21-26
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    • 2008
  • We fabricated nano-particles of ZnO, $In_2O_3$ and $SnO_2$ by using the chemical reaction between metal thin films and polyamic acid. The average size and density of these ZnO, $In_2O_3$ and $SnO_2$ nano-particles was approximately 10, 7, and 15 nm, and $2{\times}10^{11},\;6{\times}10^{11},\;2.4{\times}10^{11}cm^{-2}$, respectively. Then, we fabricated nano-floating gate memory (NFGM) devices with ZnO and $In_2O_3$ nano-particles embedded in the devices' polyimide dielectrics and silicon dioxide layers as control and tunnel oxides, respectively. We measured the current-voltage characteristics, endurance properties and retention times of the memory devices using a semiconductor parameter analyzer. In the $In_2O_3$ NFGM, the threshold voltage shift (${\Delta}V_T$) was approximately 5 V at the initial state of programming and erasing operations. However, the memory window rapidly decreased after 1000 s from 5 to 1.5 V. The ${\Delta}V_T$ of the NFGM containing ZnO was approximately 2 V at the initial state, but the memory window decreased after 1000 s from 2 to 0.4 V. These results mean that metal-oxide nano-particles have feasibility to apply NFGM devices.

Menopause and Cognitive Function : Hospitalized Female Patients with Depression (여성 우울증 입원 환자에서 폐경 여부에 따른 인지기능의 차이)

  • You, Ji-Young;Min, Jung-Ah;Jeon, Yang-Whan;Han, Sang-Ick;Park, E-Jin
    • Korean Journal of Biological Psychiatry
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    • v.23 no.4
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    • pp.199-204
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    • 2016
  • Objectives Although forgetfulness is a common complaint among menopausal depressed women, there is still a debate about the relationship between memory impairment and menopause. The aim of this study is to examine whether menopause is related to cognitive decline among women with depressive disorders. We hypothesized that postmenopausal depressed women show generally poorer performance than premenopausal depressed women on various cognitive function tests. Methods With a retrospective chart review, we identified a total of 87 female patients (45 premenopausal patients and 42 postmenopausal patients) who were hospitalized with depressive disorders from 2000 to 2016. Demographic and clinical variables and cognitive test results were compared between two groups. Results Education year is longer in premenopausal group than postmenopausal group whereas clinical characteristics (illness duration, recurrence, and symptom severity) and mean Intelligence Quotient (IQ) were similar between two groups. The postmenopausal group took longer time for Bender-Gestalt Test (BGT) recall, Trail Making Test (TMT)-A, and TMT-B than the premenopausal group. After controlling for age and education, significant difference was remained for BGT recall (p = 0.029). Conclusions Postmenopausal state may be related with decline of visuospatial memory function, in particular, among depressed female patients. Other areas of cognitive function including complex attention, verbal memory, auditory memory, and working memory might be interpreted while considering age and education level.

Effects of Brain Spinning Program on Cognitive Function, Body Composition, and Health Related Fitness of Children and Adolescents (브레인스피닝 프로그램이 소아청소년의 인지기능, 신체조성, 건강관련체력에 미치는 영향)

  • Jun-Hyeok Kim;Wook Song;In-Soo Song;Hyun-Jun Kim;Byung-Gul Lim;Jung-Yoon Hur
    • Journal of The Korean Society of Integrative Medicine
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    • v.12 no.1
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    • pp.83-96
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    • 2024
  • Purpose : This study was conducted to determine the effects of a brain spinning program on cognitive function, body composition, health related fitness and physical self-efficacy of children and adolescents. Methods : This study, 34 children and adolescents were selected and divided into two groups : the exercise group (n=16), which received a brain spinning program and the control group (n=16), which did not receive any exercise program. The program was conducted for 30 minutes three times a week for 4 weeks, and the cognitive function, body composition, health related fitness and physical self-efficacy were measured both before and after the program. Results : The exercise group, which received a brain spinning program showed a significant increase in short-term memory (p<.05) and working memory (p<.01), and muscle mass increased significantly only in the exercise group (p<.05). In addition, left grip strength increased in the exercise group (p<.01), and the maximum oxygen intake decreased significantly only in the control group (p<.05), and Sit-forward bend increased significantly only in the exercise group (p<.01). Physical self-efficacy significantly increased only in the exercise group (p<.05). Conclusion : In summary, short-term memory, cognitive efficiency, working memory, muscle mass, left grip strength, maximum oxygen intake, and left forward bending in children and adolescents significantly increased after the 4-week brain spinning program. However, the control group that was not provided with the 4-week brain spinning program showed a significant increase in body weight and a significant decrease in maximum oxygen intake. In conclusion, the 4-week brain spinning program has positive effects on short-term memory, cognitive function, muscle mass, muscle strength, cardiorespiratory endurance, flexibility, and physical self-efficacy.

A 3D Memory System Allowing Multi-Access (다중접근을 허용하는 3차원 메모리 시스템)

  • 이형
    • Journal of KIISE:Computer Systems and Theory
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    • v.32 no.9
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    • pp.457-464
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    • 2005
  • In this paper a 3D memory system that allows 17 access types at an arbitrary position is introduced. The proposed memory system is based on two main functions: memory module assignment function and address assignment function. Based on them, the memory system supports 17 access types: 13 Lines, 3 Rectangles, and 1 Hexahedron. That is, the memory system allows simultaneous access to multiple data in any access types at an arbitrary position with a constant interval. In order to allow 17 access types the memory system consists of memory module selection circuitry, data routing circuitry for READ/WRITE, and address calculation/routing circuitry In the point of view of a developer and a programmer, the memory system proposed in this paper supports easy hardware extension according to the applications and both of them to deal with it as a logical three-dimensional away In addition, multiple data in various across types can be simultaneously accessed with a constant interval. Therefore, the memory system is suitable for building systems related to ,3D applications (e.g. volume rendering and volume clipping) and a frame buffer for multi-resolution.

GLOBAL EXISTENCE AND STABILITY FOR EULER-BERNOULLI BEAM EQUATION WITH MEMORY CONDITION AT THE BOUNDARY

  • Park, Jong-Yeoul;Kim, Joung-Ae
    • Journal of the Korean Mathematical Society
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    • v.42 no.6
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    • pp.1137-1152
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    • 2005
  • In this article we prove the existence of the solution to the mixed problem for Euler-Bernoulli beam equation with memory condition at the boundary and we study the asymptotic behavior of the corresponding solutions. We proved that the energy decay with the same rate of decay of the relaxation function, that is, the energy decays exponentially when the relaxation function decay exponentially and polynomially when the relaxation function decay polynomially.

Functional Neuroanatomy of Memory (기억의 기능적 신경 해부학)

  • Lee, Sung-Hoon
    • Sleep Medicine and Psychophysiology
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    • v.4 no.1
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    • pp.15-28
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    • 1997
  • Longterm memory is encoded in the neuronal connectivities of the brain. The most successful models of human memory in their operations are models of distributed and self-organized associative memory, which are founded in the principle of simulaneous convergence in network formation. Memory is not perceived as the qualities inherent in physical objects or events, but as a set of relations previously established in a neural net by simultaneousy occuring experiences. When it is easy to find correlations with existing neural networks through analysis of network structures, memory is automatically encoded in cerebral cortex. However, in the emergence of informations which are complicated to classify and correlated with existing networks, and conflictual with other networks, those informations are sent to the subcortex including hippocampus. Memory is stored in the form of templates distributed across several different cortical regions. The hippocampus provides detailed maps for the conjoint binding and calling up of widely distributed informations. Knowledge about the distribution of correlated networks can transform the existing networks into new one. Then, hippocampus consolidats new formed network. Amygdala may enable the emotions to influence the information processing and memory as well as providing the visceral informations to them. Cortico-striatal-pallido-thalamo-cortical loop also play an important role in memory function with analysis of language and concept. In case of difficulty in processing in spite of parallel process of informations, frontal lobe organizes theses complicated informations of network analysis through temporal processing. With understanding of brain mechanism of memory and information processing, the brain mechanism of mental phenomena including psychopathology can be better explained in terms of neurobiology and meuropsychology.

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Memory-Enhancing Effects of Silk Fibroin-Derived Peptides in Scopolamine-Treated Mice

  • Kang, Yong Koo;Lee, Woojoo;Kang, Byunghoon;Kang, Hannah
    • Journal of Microbiology and Biotechnology
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    • v.23 no.12
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    • pp.1779-1784
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    • 2013
  • Although enzyme-hydrolyzed silk fibroin has been reported to enhance cognitive function before, it has been still unknown which peptides can improve memory. Here we report that amino acid sequences of three novel peptides were identified from fibroin hydrolysate. Fibroin hydrolysate was obtained by hydrolysis with protease after partial hydrolysis with 5M $CaCl_2$. Synthesized peptides derived from these sequences improved scopolamine-induced memory impairments in mice. We confirmed this hydrolysate had effects that improved learning and memory abilities by performing the Rey-Kim test. From this hydrolysate of silk fibroin, amino acid sequences of eight peptides were identified by LC-MS/MS. Three peptides (GAGAGTGSSGFGPY, GAGAGSGAGSGAGAGSGAGAGY, and SGAGSGAGAGSGAGAGSGA) were synthesized to investigate whether they could improve memory. Passive avoidance test and Morris water maze test were performed, and all peptides showed memory-enhancing abilities on scopolamine-induced memory impairments in mice. In this study, we identified three novel peptides that could improve memory, and that silk fibroin hydrolysate was a mixture of various active peptides that could enhance memory.

창원시 대산면 강변충적층의 지하수위, 하천수위, 강수량의 관련성 연구

  • 정재열;함세영;김형수;차용훈;장성
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2004.04a
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    • pp.447-450
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    • 2004
  • This study was conducted to characterize groundwater and river-water fluctuations at a riverbank filtration site in Daesan-myeon adjacent to the Nakdong River, using time series analysis. Water levels from six observation wells from January 2003 to October 2003 were measured. The autocorrelation analysis indicates that the wells are divided into three groups: group 1 represents strong linearity and memory, group 2 intermediate linearity and memory, and group 3 weak linearity and memory. The analysis indicates that groundwater levels in different monitoring wells vary in response to river-water levels, groundwater withdrawal and seasonal rainfall. Cross-correlation was also divided into three groups. Group 1 shows the highest cross-correlation function (0.49 - 0.54) for a lag time of 0 hours, group 2 intermediate cross-correlation function (0.34 - 0.45), and group 3 the lowest cross-correlation function (0.23 - 0.25). Different cross-correlation functions among the 3 groups are interpreted as an effect of tile distance from the river to the pumping wells.

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Implementation of the Frame Memory Hardware for MPEG-2 Video Encoder (MPEG-2 비디오 부호화기의 프레임 메모리 하드웨어 구현)

  • 고영기;강의성;이경훈;고성제
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.24 no.9A
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    • pp.1442-1450
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    • 1999
  • In this paper, we present an efficient hardware architecture for the frame memory of the MPEG-2 video encoder. Both the total size of internal buffers and the number of logic gates are reduced by the proposed memory map which can provide an effective interface between MPEG-2 video encoder and the external DRAM. Furthermore, the proposed scheme can reduce the DRAM access time. To realize the frame memory hardware,$0.5\mu\textrm{m}$, VTI, vemn5a3 standard cell library is used. VHDL simulator and logic synthesis tool are used for hardware design and RTL (register transfer level) function verification. The frame memory hardware emulator of the proposed architecture is designed for gate-level function verification. It is expected that the proposed frame memory hardware using VHDL can achieve suitable performance for MPEG-2 MP@ML.

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