• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7437-7441
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• 2014

Background: Acceptability of self-sampling HPV testing is confirmed worldwide. However, some cultural differences may affect this question. Therefore, this study was conducted to evaluate the acceptability of self-sampling HPV testing in Thai women. Materials and Methods: One hundred women aged 30-65 years with an intact cervix were included in this study. The participants were asked to do the Pap test by physicians and then brush type self-sampling instruments were assigned for self-collection and finally completed a questionnaire for acceptability evaluation. The questionnaire contains 2 parts. Part one covered general information of the participants and part two is the acceptability questions. Results: Mean age was 40.6 years. The incidence of high risk HPV detection in this study was 16%. The most common reason for doing Pap smear was for annual checkup. On the topic of ease of use, 85 % of the subjects agreed. Most of the participants (82%) reported that they felt less pain. However, reliability of the result was not satisfactory because 37% of the participants hesitated to rely on the results of the test. According to the price, if the price is less than 1,000 Baht (32.59 Baht = 1USD), 82% of the subjects would use it for their next screening. Conclusions: The acceptability of self-sampling device in this study is quite good but the reliability of the test was questioned by some of the participants. Moreover, the price of the test in Thailand may also influence the acceptability of the test.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1325-1331
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• 2012

Tumor formation and growth is dictated by a very small number of tumor cells, called cancer stem cells, which are capable of self-renewal. The genesis of cancer stem cells and their resistance to conventional chemotherapy and radiotherapy via mechanisms such as multidrug resistance, quiescence, enhanced DNA repair abilities and anti-apoptotic mechanisms, make it imperative to develop methods to identify and use these cells as diagnostic or therapeutic targets. Aldehyde dehydrogenase 1 (ALDH1) is used as a cancer stem cell marker. In this study, we evaluated ALDH1 expression in CaSki, HeLa and SiHa cervical cancer cells using the Aldefluor method to isolate ALDH1-positive cells. We showed that higher ALDH1 expression correlated with significantly higher rates of cell proliferation, microsphere formation and migration. We also could demonstrate that SiHa-ALDH1-positive cells were significantly more tumorigenic compared to SiHa-ALDH1-negative cells. Similarly, SiHa cells overexpressing ALDH1 were significantly more tumorigenic and showed higher rates of cell proliferation and migration compared to SiHa cells where ALDH1 expression was knocked down using a lentivirus vector. Our data suggested that ALDH1 is a marker of cervical cancer stem cells and expand our understanding of its functional role.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.346-350
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• 2009

Objective : The purpose of this study was to analyze in detail the relationship between outcome and time course of effect in medically refractory primary cervical dystonia (CD) with phasic type that was treated by bilateral globus pallidus internus (Gpi) deep brain stimulation (DBS). Methods : Six patients underwent bilateral implantation of DBS into the Gpi under the guide of microelectrode recording and were followed for $18.7{\pm}11.1$ months. The mean duration of the CD was $5.8{\pm}3.4$ years. The mean age at time of surgery was $54.2{\pm}10.2$ years. Patients were evaluated with the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) and relief scale using patient self-reporting. Results : The TWSTRS total scores improved by 64.5%, 65.5%, 75.8%, and 76.0% at 3, 6, 12 months, and at the last available follow-up after surgery, respectively. Statistically significant improvements in the TWSTRS scores were observed 3 months after surgery (p=0.028) with gradual improvement up to 12 months after surgery, thereafter, the improvement was sustained. However, there was no statistically significant difference between the scores at 3 and 12 months. Subjective improvement reported averaged $81.7{\pm}6.8%$ at last follow-up. Mild dysarthria, the most frequent adverse event, occurred in 3 patients. Conclusions : Our results show that the bilateral Gpi-DBS can offer a significant therapeutic effect from 3 months postoperatively in patients with primary CD with phasic type, without significant side effects.

• 정신신체의학
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• 제20권2호
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• pp.120-126
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• 2012

연구목적 : 흉통을 호소하여 방문한 환자를 대상으로 우울, 불안, 자존감, 그리고 삶의 질 을 조사하고, 전형적 흉통과 비전형적 흉통에 따른 차이를 비교하였다. 방 법 : 39명의 흉통 환자와 40명의 대조군을 대상으로 하였으며, 순환기 내과 전문의의 문진과 심장 전산화 단층촬영, 답차운동부하검사, 관상동맥조영술 등을 시행하여 전형적 흉통과 비전형적 흉통을 감별하였다. 우울, 불안, 자존감, 그리고 삶의 질을 평가하기 위해 BDI(Beck's Depression scale), STAI(State trait anxiety inven-tory), RSES(Rosenberg Self-esteem Scale), SBQOL(SmithKlein Beecham Quality of Life Scale)를 적용하였다. 결 과 : 심질환의 위험인자는 가족력을 제외하고는 전형적 흉통군, 비전형적 흉통군, 그리고 대조군 간에 차이가 없었다. 우울은 대조군에 비해 두 가지 흉통군 모두에 더 높았으나 흉통군 간에는 차이가 없었다. 불안은 대조군에 비해 두 가지 흉통군 모두에서 더 높았고, 전형적 흉통군에 비해 비전형적 흉통군에서 더 높았다. 자존감과 삶의 질은 대조군과 전형적 흉통군에 비해 비전형적 흉통군에서 더 낮았다. 결 론 : 흉통환자에서 불안과 우울에 대한 평가와 개입이 필요하며, 특히 비전형적 흉통환자에서는 자존감과 삶의 질 저하에 대한 접근도 병행이 되어야 함을 시사한다.

• 미술이론과 현장
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• 제8호
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• pp.145-162
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• 2009

Space is a phenomenon which is formed in the connection between environment and human beings and public space is built by a complex phenomenon of space. Each and every individual is connected to an environment and these individuals are connected to one another. A public commemorative space means souvenir and memorial which is designed for special purpose of remembrance of a specific area. One of the purposes of public commemorative space is memorial and that is the reason of doing public relation and educating citizens over the transom. However, the meaning and value of commemorative subject cannot be delivered or stuffed one-sidely. The target who receives messages from public commemorative space has reinterpreted the messages of his own with his personal experience, knowledge and sensitivity. It results in an unexpected phenomenon of public commemorative space. Therefore, public commemorative space should be considered in a mutual communication structure rather than a purpose of memorial itself. Korean public commemorative space is focused on public relation and education for memorial. In other words, Korean public commemorative space is neglected its important possibility of the productive chapter of mutual communication. The mutual communication structure of public commemorative space which is based on variety and haecceity is ripped up by the message over the transom. It destroys the self-control and creativity of public commemorative space, and derives a negative result. By studying the function and meaning of public commemorative space, we should make the best use of it.

• 대한지리학회지
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• 제48권4호
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• pp.589-607
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• 2013

치유의 글쓰기는 자기 존재의 의미를 되새기며 내면의 깊은 정서를 표현하는 글쓰기이다. 최근 학술적 영역에서 치유의 기제로 장소에 관한 관심이 증가하고 있는 시점에서, 이 연구는 장소와 기억의 호혜성에 관한 논의를 중심으로 치유의 촉매로서 장소가 갖는 의미를 고찰하고 장소를 촉매로 한 치유의 글쓰기의 실제 사례들을 해석해 본 것이다. 이를 위해 '나를 키운 장소' 라는 글쓰기 주제를 추출하였고, 이를 현장에 적용하여 학생들의 글 자료들에 나타난 다양한 치유적 양태들을 해석하였다. 이 과정에서 치유의 글쓰기에서 강조되고 있는 바, 사람들마다 자신의 일생에서 가장 강한 영향으로 '기억되고 있는' 내면의 깊은 감정에는 언제나 그/그녀의 '장소'가 함께 한다는 사실과 그러한 장소가 글쓰기 과정에서 치유의 촉매로 기능하고 있음을 확인할 수 있었다.

• Journal of Digestive Cancer Research
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• 제10권2호
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• pp.92-98
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• 2022

Self-expandable metal stent (SEMS) is effective for biliary drainage, especially in pancreaticobiliary cancer. The mechanical properties, material, and design of SEMS are important in preventing recurrent biliary obstruction and complication. Radial and chronic expansion forces play roles in preventing stent migration and collapse. Complications, such as stent impaction, cholecystitis, and pancreatitis, were related to the axial force. The nickel-titanium alloy shows more flexibility, conformability, and optimal axial force compared to previously used stainless steel. Additionally, the stent structure affected the mechanical properties of SEMS. Therefore, understanding the mechanical properties, material, and design of SEMS will provide the best outcome for biliary drainage, as well as better SEMS development.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.295-300
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• 2012

Breast self-examination (BSE) is important for early diagnosis of breast cancer (BC). However, the majority of Turkish women do not perform regular BSE. We aimed to evaluate the effects of education level on the attitudes and behaviors of women towards BSE. A descriptive cross-sectional study was conducted on 413 women (20-59 years), divided into university graduates (Group I, n = 224) and high school or lower graduates (Group II, n = 189). They completed a 22-item scale assessing the knowledge level, attitudes and behaviors regarding BSE, and the Turkish version of the Champion's Revised Health Belief Model. A significantly higher number of women in Group II did not believe in early diagnosis of BC. A significantly higher number of Group I had conducted BSE at least once, and their BSE frequency was also significantly high. Moreover, a significantly lower number of Group I women considered themselves to not be at risk for BC and the scores for "perceived susceptibility" and "perceived barriers" were significantly higher. Logistic regression analysis identified the university graduate group to have a higher likelihood of performing BSE, by 1.8 times. Higher educational levels were positively associated with BSE performance. Overall, the results suggest that Turkish women, regardless of their education level, need better education on BSE. Consideration of the education level in women will help clinicians develop more effective educational programs, resulting in more regular practice and better use of BSE.

• 기본간호학회지
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• 제15권2호
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• pp.206-212
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• 2008

Purpose: This study was done to identify the effects of self-care behavior, self-efficacy and family support on the occurrence of peritonitis in patients on CAPD (Continuous Ambulatory Peritoneal Dialysis). Methods: Data were collected from 81 patients on CAPD either as out-patients or in-patients between July and September 2004. Data were analyzed to identify relevant frequencies, percentages, averages, and standard deviations, and t-test and logistic regression were done using SPSS WIN 10.0 Results: a) Mean score for self-care behavior was 2.9 (of a possible 4.0), for general self-efficacy, 3.2 (of a possible 5.0), for specific self-efficacy 3.5 (of a possible 5), and for family support, 3.7 (of a possible 5). Family support generally showed the most positive results. b) Occurrence of peritonitis was not affected by general characteristics. c) There was a significant difference in the occurrence of peritonitis in terms of self-efficacy. Patients with peritonitis had lower self-efficacy than those who did not. 4) Of the four factors reviewed in relation to peritonitis, only self-efficacy was statistically significant: an increase in self- efficacy by 1 point increased the occurrence of peritonitis by 0.90. Conclusion: Among the four factors potentially affecting peritonitis in CAPD patients, general self-efficacy was found to be the main factor influencing the occurrence of peritonitis.

• 대한통합의학회지
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• 제8권1호
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• pp.87-99
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• 2020

Purpose : This study aims to investigate the effect of somatosensory stimulation on the upper limb sensory and function and self-esteem of stroke patients. Methods : This study period was march 4 to april 4 (5 weeks). The subject were 20 stroke patients with somatosensory impairment in B hospital, seongnam, gyeonggi province. They were devided into two group-experimental and control-with 10 members each. The members of the experimental group underwent somatosensory stimulation, whereas the members of the control group underwent an occupation-based intervention for 5 weeks. Thirty-minute therapy was provided 3 times per week for 5 weeks. Before and after the intervention, both groups were evaluated via light touch, static two-point discrimination, stereognosis, Fugl-Meyer assessment (FMA), and self-esteem scale Results : In this study, light touch was not significant in both groups. Static two-point discrimination was significant among the experimental group member's index fingers. Among the control group members, it was significant in the ring finger. The comparison between the two groups was significant in the index finger. The stereognosis results were significant in the experimental group but not in the control group. The comparison between the groups after the intervention was not significant. FMA was significant in the shoulder/ elbow/ forearm (SEF), hand and coordination among the experimental group. Among the control group, it was significant in the SEF and hand. The comparison between the groups was significant in the SEF, hand and coordination. The self-esteem scale results were significant among both groups, and the comparison between the group's score was likewise significant. Conclusion : In conclusion, somatosensory stimulation therapy increases the static two-point discrimination, stereognosis, upper extremity function, and self-esteem of patients with stroke. Therefore, while somatosensory stimulation therapy is not the best therapy, it is one of the best occupational therapies for stroke patients.