• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.36 no.5
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• pp.434-437
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• 2010

A melanotic neuroectodermal tumor of infancy (MNTI) is a uncommon osteolytic pigmented neoplasm that primarily affects the jaws of newborn infants. Most patients (> 90%) present with the tumor in the first year of life. Approximately 65% form in the maxilla, 11% in the mandible, 5% in the brain and elsewhere. MNTI is normally benign, but up to 15% may recur and a few have metastasized. Approximately 200 cases of MNTI have been reported but only 2 of them presented as multifocal. A case of MNTI in a 7 month old boy was encountered. The chief complaint was maxillary anterior ridge swelling. The incisional biopsy findings were MNTI. Two months after the first operation, mild swelling of another site was observed. The infant was examined periodically since undergoing two procedures with no recurrence. This case demonstrates the possibility of a multicentric MNTI. We report a multicentric MNTI with a review of the relevant literature.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.13 no.4
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• pp.436-443
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• 1991

A case of melanotic neuroectodermal tumor of infancy(MNTI) in 5 month old girl is presented with review of the literature. The review of literature indicated that there have been 189 reported cases of this lesion and there were 9 cases of malignant tumor for a rate of 4.8%. This rate of malignancy is very high in view of the fact that the tumor has been described as benign. And immunohistochemical study using avidin-biotin conjugate method demonstrated that this tumor had been originated from neural crest.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.13 no.1
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• pp.77-81
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• 1991

The melanotic neuroectodermal tumor of infancy(MNTI) is a rare childhood neoplasm with a clinical presentation. Because of its rapid growth pattern and bone resorption, the lesion can be mistaken for a malignant neoplasm. Although an aggressive growth rate and radiographic appearance, the MNTI almost always behaves in a benign fashion and can be treated with total excision. We presented the MNTI occured in the left maxillary alveolar ridge of 5 month old female infant. showing bluish enlargenent of alveolar mucosa with the displacement of central decidious incisor. And after the surgical excision of the mass, there is no recurrent tendency.