• 제목/요약/키워드: MegaStudy

검색결과 471건 처리시간 0.028초

Development of Strain-Specific Primers for Identification of Bifidobacterium bifidum BGN4

  • Youn, So Youn;Ji, Geun Eog;Han, Yoo Ri;Park, Myeong Soo
    • Journal of Microbiology and Biotechnology
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    • 제27권5호
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    • pp.909-915
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    • 2017
  • Bifidobacterium bifidum BGN4 (BGN4) has many proven beneficial effects, including antiallergy and anticancer properties. It has been commercialized and used in several probiotic products, and thus strain-specific identification of this strain is very valuable for further strain-dependent physiological study. For this purpose, we developed novel multiplex polymerase chain reaction (PCR) primer sets for strain-specific detection of BGN4 in commercial products and fecal samples of animal models. The primer set was tested on seven strains of B. bifidum and 75 strains of the other Bifidobacterium species. The BGN4-specific regions were derived using megaBLAST against genome sequences of various B. bifidum databases and four sets of primers were designed. As a result, only BGN4 produced four PCR products simultaneously whereas the other strains did not. The PCR detection limit using BGN4-specific primer sets was $2.8{\times}10^1CFU/ml$ of BGN4. Those primer sets also detected and identified BGN4 in the probiotic products containing BNG4 and fecal samples from a BGN4-fed animal model with high specificity. Our results indicate that the PCR assay from this study is an efficient tool for the simple, rapid, and reliable identification of BGN4, for which probiotic strains are known.

Tracing the Giant Metal-poor Halo Around the Sombrero

  • Kang, Jisu;Lee, Myung Gyoon;Jang, In Sung;Ko, Youkyung;Sohn, Jubee;Hwang, Narae
    • 천문학회보
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    • 제41권2호
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    • pp.30.2-30.2
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    • 2016
  • M104 (NGC 4594, the Sombrero) is an intriguing disk galaxy classified as an elliptical galaxy nowadays. It hosts a luminous bulge and a massive disk, but it is still mysterious how M104 acquired such peculiar structures. Globular clusters are an useful tracer to investigate the formation history of early-type galaxies. In this study we present a wide field imaging study of the globular clusters in M104. Using wide ($1^{\circ}{\times}1^{\circ}$) and deep ugi images of M104 obtained with the CFHT/MegaCam observations, we detect a large number of globular clusters. The color distribution of these globular clusters shows that there are two subpopulations: a metal-poor system and a metal-rich system. The radial number density of the metal-poor globular clusters shows a long tail reaching R ~ 30' (~ 80 kpc), indicating clearly the existence of a giant metal-poor halo in M104. This result is consistent with the previous studies on the dual halos of massive early-type galaxies. We will discuss implications of these results in relation with the formation history of M104.

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시뮬레이션 교육이 간호사의 전문심장소생술 수행능력에 미치는 효과 (Effects of simulation-based training on the critical care nurses' competence of advanced cardiac life support)

  • 백지윤
    • 중환자간호학회지
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    • 제1권1호
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    • pp.59-71
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    • 2008
  • Purpose: This study was to identify the effects of simulation-based training for advanced cardic life support on the competence of nurses in critical care settings. Methods: In this study, a nonequivalent control pretest-post test quasi-experimental design was used. Data were collected from May 1 to June 1, 2006 at one general hospital in W city. Among 40 nurses in critical care settings, twenty were assigned to the experimental group and twenty to the control group. Nurses in the experimental group received simulation-based training for advanced cardiac life support. Measurement tool were ACLS related knowledge and skills developed by AHA & Mega Code (2005) and some items were modified. The collected data were statistically processed using SPSS version 12.0 for Windows, and analyzed using descriptive statistics, $X^2$test, t-test, paired ttest, Pearson correlation coefficients. Results: 1) Hypothesis 1“: Nurses who received simulationbased training would have more knowledge of advanced cardiac life support than nurses who received traditional training”, was supported (t=11.51, p=.00). 2) Hypothesis 2: “Nurses who received simulation-based training would have better advanced cardiac life support skills than nurses who received traditional training”, was supported (t=2.38, p=.00). Conclusion: Simulation-based training for advanced cardiac life support is an effective strategy for increasing the competence of nurses in advanced cardiac life support in critical care settings.

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발전용 대형 엔진 적용을 위한 천연가스-디젤 혼소에 대한 수치 해석적 연구 (Numerical Study on Co-Combustion in Diesel Engine for Heavy-Duty Power Generation)

  • 서동균;허광범;정연태;김의현
    • 한국수소및신에너지학회논문집
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    • 제26권4호
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    • pp.369-376
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    • 2015
  • Recently KEPCO, KOGAS and other institutions are jointly conducting an R&D for the development and demonstration of the power generation system based on a natural gas/diesel engine on an island. As a preliminary study, co-combustion in the dual fuel engine, which is expected to produce a few mega-watts of electricity, was modeled and calculated using computational fluid dynamics (CFD). The applied key assumptions are 2-dimensional axisymmetric, transient and static volume chemical reaction. Based on the selected blending ratio, which is the key operating condition, natural gas is substituted instead of diesel fuel (basis of high heating value). Results showed that as the blending ratio increases, the reaction rate of the combustion increases and thus maximum temperature is reached more rapidly. For the optimal performance, various geometric or operational studies will further be conducted.

ARIMA-Intervention 시계열모형을 활용한 제주 국내선 항공여객수요 추정 (A Study on the Air Travel Demand Forecasting using time series ARIMA-Intervention Model)

  • 김민수;김기웅;박성식
    • 한국항공운항학회지
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    • 제20권1호
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    • pp.66-75
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    • 2012
  • The purpose of this study is to analyze the effect of intervention variables which may affect the air travel demand for Jeju domestic flights and to anticipate the air travel demand for Jeju domestic flights. The air travel demand forecasts for Jeju domestic flights are conducted through ARIMA-Intervention Model selecting five intervention variables such as 2002 World Cup games, SARS, novel swine-origin influenza A, Yeonpyeongdo bombardment and Japan big earthquake. The result revealed that the risk factor such as the threat of war that is a negative intervention incident and occurred in Korea has the negative impact on the air travel demand due to the response of risk aversion by users. However, when local natural disasters (earthquakes, etc) occurring in neighboring courtiers and global outbreak of an epidemic gave the negligible impact to Korea, negative intervention incident would have a positive impact on air travel demand as a response to find alternative due to rational expectation of air travel customers. Also we realize that a mega-event such as the 2002 Korea-Japan World Cup games reduced the air travel demand in a short-term period unlike the perception in which it will increase the air travel demand and travel demands in the corresponding area.

IDEF 방법론을 이용한 발주자 공정관리 프로세스 규명에 관한 연구 (A Study of the Identify about Scheduling Process at Owner's Position)

  • 이태식;김영현
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2001년도 학술대회지
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    • pp.454-457
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    • 2001
  • 성공적인 공사수행을 위하여 공정관리는 건설공사 참여주체 모두가 관심가지고 지속적으로 관리해나가야 하는 부분이다. 또한 세부공정을 관리하는 시공자의 책임만 중요한 것이 아니라 정해진 공기 내의 공사수행으로 그 목적한 바를 이뤄야하는 발주자에게 있어서도 지속적으로 관리해야하는 부분이다. 특히, 대형공사의 경우 발주자는 시공자를 지휘 · 감독하기 위해 공정관리 프로세스를 이용하여 진도율을 관리해야 한다 이때 공정이 지연되거나 변경될 경우 빠른 시간 내에 만회대책을 수립하여야 한다. 본 연구에서는 이러한 발주자의 공정관리 프로세스를 IDEF 방법론을 이용하여 규명하여 건설 프로세스 모델을 제시하고자 한다.

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DOE를 적용한 카메라폰 모듈용 비구면 Glass 렌즈의 가압성형조건 연구 (A Study on Pressing Conditions in the molding of Aspheric Glass Lenses for Phone Camera Module using Design of Experiments)

  • 김혜정;차두환;이준기;김상석;김정호
    • 한국전기전자재료학회논문지
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    • 제20권8호
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    • pp.720-725
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    • 2007
  • This study investigated the pressing conditions in the molding of aspheric glass lenses for the mega pixel phone camera module using the DOE method. Tungsten carbide (WC; Japan, Everloy Co., 002K),which contained 0.5 w% cobalt (Co), was used to build the mold. The mold surface was ultra-precision ground and polished, and its form accuracy (PV) was 0.85um in aspheric surface. We selected four factors, pressing temperature, force and time of first step, and force of second step, respectively, as the parameters of the pressing process. in order to reduce the number of experiments, we applied fractional factorial design considering the main effects and two-way interactions. The analysis results indicate that the only two main effects, the pressing temperature and the time of pressing step 1, are available for the form accuracy (PV) of the molded lens. The analysis results indicated that the best combination of the factors for lowering the form accuracy(PV) value of molded lens was to have them at their low levels.

High-Rise Urban Form and Environmental Performance - An Overview on Integrated Approaches to Urban Design for a Sustainable High-Rise Urban Future

  • Yang, Feng
    • 국제초고층학회논문집
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    • 제5권2호
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    • pp.87-94
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    • 2016
  • High-rise as a building typology is gaining popularity in Asian mega-cities, due to its advantages in increasing volumetric density with limited land resources. Numerous factors contribute to the formation of high-rise urban form, from economical and institutional, environmental to socio-political. Environmental concerns over the impact of rapid urbanization in developing economies demand new thought on the link between urban environment and urban form. Outdoor and indoor climate, pedestrian comfort, and building energy consumption are all related to and impacted by urban form and building morphology. There are many studies and practices on designing individual "green" high-rise buildings, but far fewer studies on designing high-rise building clusters from the perspective of environmental performance optimization.. This paper focuses on the environmental perspective, and its correlation with the evolution of the high-rise urban form. Previous studies on urban morphology in terms of environmental and energy performance are reviewed. Studies on "parameterizing" urban morphology to estimate its environmental performance are reviewed, and the possible urban design implications of the study are demonstrated in by the author, by way of a microclimate map of the iconic Shanghai Xiao Lujiazui CBD. The study formulates the best-practice design guidelines for creating walkable and comfortable outdoor space in a high-rise urban setting, including proper sizing of street blocks and building footprint, provision of shading, and facilitating urban ventilation.

도시재생사업 성과지표와 위험요인 연계 방안 연구 (A Study on the Mapping of Risk Factor with Performance Index in Urban Regeneration Project)

  • 유영정;김선규
    • 한국건설관리학회:학술대회논문집
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    • 한국건설관리학회 2008년도 정기학술발표대회 논문집
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    • pp.497-500
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    • 2008
  • 최근 국내외에서 도시재생사업이 활발히 진행되고 있다. 이러한 도시재생사업은 사업주체 및 이해관계자가 다양하고, 복잡하며, 대규모의 긴 생애주기를 가지고 있다. 또한 대부분 입체 복합공간 개발 형태의 메가프로젝트라는 특징을 나타내고 있다. 이러한 대규모의 도시재생사업은 사업수행과정에서 많은 위험요인들이 존재하며, 그와 더불어 효율적이고 지속적인 성과관리가 필요하다. 그러나 국내의 성과관리는 건설업의 특성을 반영하지 못하고 있으며, 위험과 연계된 연구는 미비하다. 그래서 본 연구는 효율적인 성과관리를 위한 위험과 연계된 성과측정지표를 도출하기 위한 기초연구로 맵핑(mapping)을 통해 성과측정을 위한 성과지표와 위험요인을 연계하는 방법을 제시하고자 한다.

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인공지능(AI) 산업의 VC 투자 동향과 시사점 (Trends and Implications of Venture Capital Investment in the Artificial Intelligence Industry)

  • 최새솔;주보라;연승준
    • 전자통신동향분석
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    • 제37권6호
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    • pp.1-10
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    • 2022
  • Artificial intelligence (AI) has rapidly diffused across industries and societies as nations' essential strategic technology. In innovative technology, such as AI, a startup leads to technological innovation and significantly impacts the expansion of relevant industries. Thus, this study examined the trend of AI startup venture capital (VC) investments globally, focusing on ① noteworthy VC investment statuses (the number and size of the investment, company establishment, and corporate collection), ② the characteristics of each key nation's investments, and ③ the characteristics of each submarket's investments. Among the 11 countries, the results showed that Korea ranked near the bottom for absolute quantitative measures, including the number and size of investments, company establishment, and corporate collection. However, Korea has built a foundation of catching up with what AI-leading countries have established, considering Korea's high growth rate in the number and size of investments and a recent mega-round. This study has practical implications in that it determined the AI startup VC investment status of Korea's rival countries, not only G2 (US and China). The results can be used in policy-making. Furthermore, identifying the AI industry's submarkets and analyzing each market's VC investment status could be used to establish strategies for the AI industry and R&D.