• Preventive Nutrition and Food Science
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• 제8권3호
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• pp.289-293
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• 2003

Antioxidant activity and nicotine degradation activity (NDA) of 21 medicinal herbs were determined by using a 1,1-diphenol-2-picrylhydrazyl (DPPH) method and a PLC/PRF5 human liver cell line method, respectively, to develop an anti-smoking aid. The highest and lowest antioxidant activities represented by $IC_{50}$/ value were 30 $\mu$g/mL of Eugenia caryophyllus and 3,270 $\mu$g/mL of Panax ginseng C. A. Meyer, respectively. Antioxidant activity of Eugenia caryophyllus was equal to 38.0$\pm$1.2 mg VCEAC(vitamin C equivalent antioxidant capacity)/ g herb. The highest and lowest NDA values were 1.81 of Astrgalus membranaceus Bunge and 1.01 of Raphani seed and Lespedeza tomentosa Sieb, respectively. Eleven medicinal herbs with high antioxidant activity and/or NDA were selected to make an herbal tea. The herbal tea had high antioxidant activity (50 $\mu$g/mL $IC_{50}$/ and 22.4$\pm$1.4 mgVCEAC/g) and NDA (1.243). The medicinal herb tea could help smokers quitting smoking by degrading and exhausting nicotine accumulated in body and removing reactive oxygen species.

• 동의생리병리학회지
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• 제25권5호
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• pp.759-764
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• 2011

Through analyzing the frequencies of medicinal herb combinations in the prescriptions of "wenrejingwei(溫熱經緯)", we could understand the characteristics of prescription composition and author's medical thoughts. So we conducted this study that analyze combination of 187 medicinal herbs in 113 prescriptions, and found meaningful combinations of 273. Among these, the most meaningful combinations are the one of 7 herbs, Glycyrrhiza uralensis Fischer, Zingiber Rhizoma, Ziziphus jujube Mille, Pinellia ternata Breitenbach, Panax ginseng C.A.Meyer, Cyprinus carpio, Coptis chineis Franch. These are the same medicinal herbs which consist of Banhasasim-tang(banxiaxiexin-tang). It means these combinations are effective in stuffiness caused by stomach deficiency. In conclusion, prescriptions of "wenrejingwei(溫熱經緯)" involve herbs mostly used to treat stuffiness caused by stomach deficiency, and this is the author's important one of medical view points.

• 생약학회지
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• 제48권1호
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• pp.56-62
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• 2017

The aim of this study was to screen the contamination by ochratoxin A of mycotoxins in various medicinal herbs. We conducted a survey of ochratoxin A in medicinal herb on the retail market in Incheon in 2016. 116 medicinal herb samples were evaluated for the ochratoxin A contamination. They were analyzed for ochratoxin A using immunoaffinity column and high-performance liquid chromatography(HPLC)-fluorescence detection and the positive samples were confirmed using HPLC-tandem mass spectrometry. Ochratoxin A was detected in 4 medicinal herb samples; the concentrations of ochratoxin A were containing between 20.11 and $372.90{\mu}g/kg$. This study shows that in general, this kind of commodity may be contaminated by mycotoxins. Also this contamination is not limited to only aflatoxin of mycotoxins.

• 대한한의학회지
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• 제35권1호
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• pp.99-113
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• 2014

Objectives: To provide theoretical basis for the classification of medicinal moxibustion(藥灸劑) in Health Insurance Medical Benefit in Korea through investigating trend of judicial precedents on indirect moxibustion and usage of medicinal moxibustion in "Donguibogam". Methods: We analyzed statistical data of moxibustion from Health Insurance Review & Assessment Service and National Health Insurance Statistical Yearbook. We investigated major judicial precedents on indirect moxibustion to find out some trend and we searched the usages of medicinal moxibustion in "ZhenJiuDaCheng" and "Donguibogam". Results: According to recent judicial precedents, indirect moxibustion with equipment is no loner regarded as Korean Medical Procedure. In composition of 'Oriental Health Treatment', amount for acupuncture has gradually decreased instead, amount for moxibustion has increased steadily for 5 years. Medicinal moxibustion(藥灸劑) is often used as a form of indirect medicinal moxibustion with moxa in "Donguibogam". Argyi Folium, Moschus, Natrii Chloridium, Radix Preparata, Realgar and Olibanum are most frequently used for medicinal moxibustion in "Donguibogam". Medicinal moxibustions are composed of simple prescription or herb-pair or multiple prescription in "Donguibogam". Conclusions: In Health Insurance Medical Benefit in Korea, under the division of moxibustion, direct medicinal moxibustion and indirect medicinal moxibustion should be classified in addition.

• 한국식품저장유통학회지
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• 제5권1호
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• pp.13-21
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• 1998

Korean medicinal herb extracts(KMHE) were applied to the preservation of greenhouse produce in order to prove their effectiveness. KMHE showed remarkable antimicrobial effects against Bacillus cereus, Peudomonas syringae, and Corynebacterium xerosis causing the postharvest decay of greenhouse produce. Among KMHE the extracts of Rheum palmatum L. and Coptis chinensis Franch most obviously inhibited the growth of microorganims causing the Postharvest decay of greenhouse produce, which destroyed to undetectable levels when treated with more than 500ppm of KMHE. The activities of KMHE were stable in the wide spectrum of pH and temperature. Direct visualization of microbial cells by using both transmission electron microscope and scanning electron microscope showed microbial cell membrane the function of which was destroyed by treating with the dilute solutions of KMHE. This change of cellular membrane permeability could be identified in the experiment that O-nitrophenyl-$\beta$-D-galactopyranoside(ONPG), the artificial substrate of $\beta$-galactosidase, was hydrolyzed in the presence of KMHE, indicating that the membrane was perturbed by KMHE.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2007년도 춘계학술발표회
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• pp.243-244
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• 2007

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2011년도 춘계학술발표회
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• pp.374-375
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• 2011

• 식품산업과 영양
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• 제18권2호
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• pp.1-6
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• 2013

• 한국약용작물학회지
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• 제6권1호
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• pp.28-32
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• 1998

본 연구는 국내에서 재배한 서양 향신 허브식물의 무기물 함량과 항산화 활성 효과를 비교검토하기 위하여 시험한 바 그 결과를 요약하면 다음과 같다 1. 서양 허브식물은 여러 가지 종류의 무기물을 함유하고 있었으며 허브 종류별 무기물 함량은 매우 상이하였다. 캄슘함량은 borage, chicory에서 높았고 칼륨은 comfrey, borage, Parsley에서 철분은 coriander, comfrey에서 높았다. 2. 19종의 서양 허브식물에 대한 DPPH Radical 소거작용 검색에 의한 항산화 활성을 검색한 결과 spearmint, marjoram, sweet basil 및 rosemary 식물의 추출물에서 tocopherol, BHA와 유사한 활성을 나타내었다. 용매별 분획에 의한 항산화효과를 검토한 결과 MeOH ext.에서 효과를 타나내지 못한 herb종류도 용매분획에 의해 항산화 활성을 나타낼수 있음을 알 수 있었다.

• 한국약용작물학회지
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• 제27권3호
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• pp.167-172
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• 2019

Background: Angelica acutiloba Kitagawa belongs to the flowering plant family Apiaceae. Its young leaves are consumed as a vegetable, and its roots have medicinal properties. This study was conducted to analyze the seed germination characteristics of A. acutiloba according to its ripening stages. Methods and Results: The seeds were harvested from a research farm managed by the Department of Herbal Crop Research, Rural Development Administration in 2018 and were divided into six groups according to their specific gravities. In particular, we studied the effect of harvesting periods and umbel orders on seed characteristics. The results showed that the rates of germination, emergence, and early growth improved as the specific gravity of the seeds increased. In addition, the germination rates of the seeds harvested in mid July and early August were significantly higher than those harvested in the other seasons, and the seeds obtained from the first floret had the greatest mass and weight. Conclusions: In this study, we demonstrated that it is possible to improve the germination rate by appropriate selection of seeds and harvesting period both of which are closely related to seed maturity.