• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권6호
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• pp.616-621
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• 2008

Osseointegration is a result of bone formation and bone regeneration processes, which takes place at the interface between bone and implant, and it indicates a rigid fixation that can be stably maintained while functional loading is applied inside the oral cavity as well as after implant placement. Although many researches were carried out about osseointegration mechanism, but cellular and molecular events have not been clarified. With recent development of molecular biology, some researches have examined biological determinants, such as cytokine, growth factors, bone matrix proteins, during osseointegration between bone and implant surface, other researches attempted to study the ways to increase bone formation by adhering protein to implant surface or by inserting growth factors during implant placement. Cellular research on the reaction of osteoblast especially to surface morphology (e.g. increased roughness) has been carried out and found that the surface roughness of titanium implant affects the growth of osteoblast, cytokine formation and mineralization. While molecular biological research in dental implant is burgeoning. Yet, its results are insignificant. We have been studying the roles of growth factors during osseointegration, comparing different manifestations of growth factors by studying the effect of osseointegration that varied by implant surface. Of many growth factors, $TGF-{\beta}$, IGF-I, BMP2, and BMP4, which plays a significant role in bone formation, were selected, and examined if these growth factors are manifested during osseointegration. The purpose of this article is to present result of our researches and encourage molecular researches in dental implant.

• 동의생리병리학회지
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• 제29권5호
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• pp.353-360
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• 2015

In a essay that was published on 'Science' in December 2014 as a part of the supplement "The Art and Science of Traditional Medicine," the eastern and western medical theories are discussed with reference to the model-dependent realism suggested by Stephen Hawking and Leonard Mlodinow. This paper examines what the model-dependent realism is, and how it affects the future direction of researches in traditional Korean medical theories. The model-dependent realism holds a meaning in that it puts traditional medical theories in a perspective of models, and allows for application of recent studies in scientific philosophy for researches in traditional medical theories. Especially, the model studies by R. Giere et al. will help elaborate the traditional medical theories from a model perspective. From a model perspective, the 'visceral manifestation', 'meridian and collateral', 'qi-blood', 'eight principles' and 'constitution' theories of traditional medicine have the potentials to develop into valid models, and the traditional medical theory's phenomenological and holistic perspective distinguishes it from western medicine, giving it a competitive edge. In addition, the epistemological pluralism of model-dependent realism can serve as an alternative to relativism or rationalism perspective which put eastern and western medicine in opposition until now.

• 한국컴퓨터정보학회논문지
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• 제21권6호
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• pp.83-88
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• 2016

In this research aimed to deduce internal marketing factors, purpose, and their practical application by analyzing preceding researches on internal marketing of Korean medical service organization and investigating the recent trend of its research. Subjects of research are ten preceding researches that have been published in KCI records for the last five years from 2011 to 2016. Summarize result of researches, first, internal factors that were most frequently used were internal communication, compensation system, and education and training, which were used by 8(.8). Second, occupations that had most interest in the internal marketing research appeared to be nursing(.9) and administration(.3). Third, the practical application of the internal marketing appeared to be job satisfaction(.8), followed by customer orientation(.6), and organizational commitment(.4). Suggestion do, necessary to develop subordinate factors regarding the realistic internal marketing, such as both-sided internal communication enhancement, education and training, compensation system differentiated by individuals and teams, fairness in performance rating, work environment improvement, delegation of authority, career development, shared organizational vision in order to maximize job satisfaction, job commitment, and organizational commitment of employees as internal customers, before establishing strategies to satisfy patients and guardians who are external customers.

• Korean Journal of Acupuncture
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• 제25권3호
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• pp.167-174
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• 2008

Objective : To make comprehensive feature of previous researches on moxibustion, then build a basis of strategy for development of moxibustion-derived therapeutics. Methods : Surveyed 326 abstraction-containing literatures from total 467 of moxibustion-related papers in PubMed and 29 papers in Korea. Analysis was performed according to distribution by study subject, number by year, nation, research method, and its efficacy. Results : Moxibustion-related researches have been rapidly increased since 2001. The main contributive country for moxibustion research was China whileas few researches was done by Korea. The main subjects of moxibustion research are associated with immunity, inflammation, neurosystem, and digestive function. The most therapeutic roles of moxibustion were on pain control, modulation of immunity, anti-fatigue and anti-stress. Conclusion : This study will help Korean Oriental medical doctors to systematically review the moxibustion researches, and to develop more competitive therapeutics using moxibustion in global CAM field.

• 한국노년학
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• 제38권3호
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• pp.705-723
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• 2018

본 연구의 목적은 "한국노년학" 학회지에 40년간 게재된 보건 의료 건강분야 연구의 동향을 전반적으로 고찰하고 "한국노년학" 연구의 다학문적 특성과 관련하여 보건 의료 건강 부분이 나아갈 방향을 조망하기 위함이다. 이를 위해 한국노년학 창간호부터 2017년 12월 말까지 40년간 게재된 논문 중 2008년 30주년에 "한국노년학" 1권(1980년)부터 28권(2008년) 2호까지에 게재된 논문 중 건강 간호분야 및 노인보건정책 논문 분석 연구를 검토하고, 최근 10년간 게재된 논문(2008년 3호~2017년 4호) 총 655편 중 237편(전체의 36.2%)을 대상으로 분석하였고, 다음과 같은 연구동향을 확인하였다. 첫째, 최근 10년간의 연구 주제를 대표저자의 전공별로 분석한 결과 보건, 의료, 간호, 체육 분야 저자들은 주로 신체적 건강 주제의 연구를 수행하였고 복지분야 저자들은 정신적 건강 주제의 연구를 주로 다뤘다. 즉, 전반적으로 보건 의료 건강 영역에서는 신체적 건강의 연구가 주로 수행되었다. 둘째, 연구방법 분석결과, 최근 10년간 연구에서는 양적연구가 89.9%를 차지하고 있었고, 지난 30년간(1980-2008)의 연구에서도 양적연구가 81.5%로 대다수를 차지하고 있다. 최근 10년간 수행 된 질적연구는 총 11편으로 나타나 양적연구에 비해 비중이 작은 것으로 나타났으며, 포커스그룹 인터뷰 방법을 활용한 연구가 33.3%로 가장 많은 비중을 차지하는 것으로 나타났다. 셋째, 연구유형은 지난 30년간의 분석에서는 비실험연구가 82.7%였지만, 최근 10년간의 연구에서는 비실험연구가 65.4%를 차지하고 있는 것으로 나타나 보건 의료 건강영역에서 문제해결을 위한 실험연구가 증가하고 있는 것을 알 수 있었다. 넷째, 연구대상은 최근 10년간의 연구에서 건강한 노인, 도시거주 노인, 재가 노인 대상으로 한 연구가 많은 비중을 차지하였으며, 대상노인의 연령은 65세 이상 노인을 대상으로 한 연구가 60.0%로 지난 30년간의 연구에서의 42.7%보다 그 비중이 증가하였다. 대상노인의 성별에 따라 연구동향은 최근 10년간의 연구에서 남녀 모두를 대상으로 한 연구가 81.6%로 나타나 지난 30년 연구의 88.5%에 비해 조금 감소한 것으로 나타났다. 이와 같은 연구결과는 최근 10년간 보다 다양한 연구 접근이 시도되긴 하였으나 여전히 신체건강을 주제로 비실험연구설계를 적용하는 연구가 주를 이루고 있었다. 향후 노인 건강증진연구에서 통합적 다학제적 접근 및 예방적 사전적 관점의 필요성과 함께 급속한 고령화를 경험하고 초고령화가 임박한 한국적 상황을 다각적으로 분석할 수 있는 종단 연구, 질적 연구, 메타 분석 등 다양한 연구방법을 통한 심층적이고 체계적인 연구설계의 필요성을 시사하고 있다.

• 대한한의학원전학회지
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• 제21권3호
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• pp.43-58
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• 2008

Wanghogo(王好古) is a prominent doctor in Geum-Won(金元) Dynasty. He is also the inheritor of Jangwonso(張元素) and Igo(李杲) in study, and studied "Hwangjenaegyeong(黃帝內經)", "Sanghallon(傷寒論)". So, he contributed to a later age. Although we have some researches of Wanghogo, but the researches in his books are insufficient as yet. More, the publication year of his books have some different views, so I tried to study this. By this study, We can understand that Wanghogo published "Uiruwonyung(醫壘元戎)" which is for exogenous febrile disease and miscellaneous diseases in general plan of twelve meridians in 1297, "Eumjeung-yangnye(陰證略例)" which is for harm and diagnosis and treatment of Eum syndromes of exogenous febrile disease in 1303, and "Tang-aekboncho(湯液本草)" which is for property and flavor and meridian tropism of Herb and five kind of flavor's tonification and reduction, the meaning of prescription, care of health by food, "Chasananji(此事難知)" which is for meridian, Jangbu(臟腑), pathology, pathogen, clinical distinction, medical care in 1308.

• 대한한의학회지
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• 제40권4호
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• pp.84-90
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• 2019

Objectives: Chronic fatigue syndrome (CFS) is a debilitating illness impairing seriously quality of life, while CFS would be an optimized target disorder of Korean medicine. This study aims to present the recent information especially in aspect of medical policy and new diagnosis criteria for CFS. Methods: The literature survey was conducted using the terms of "chronic fatigue syndrome", "myalgic encephalomyelitis" and "fibromyalgia" in PubMed database and Google database in its entirety from January 2011 to February 2019. The in-depth review was made focusing on the changes in policy and medical perspective for CFS. Results: Recently large medical attentions and researches for CFS have been existed worldwide. By supporting of USA government, IOM made a report which leaded to a turning point in clinical practices and research in 2015. This report recommended a new name of CFS to systemic exertion intolerance disease (SEID), and new diagnostic criteria focusing on post-exertional malaise, unrefreshing sleep, cognitive impairment and orthostatic intolerance. The medical perspective also was changed into "a serious, chronic, complex, systemic disease" from a psychological-like disorder, and then UAS and EU governments sharply increased the research grants. Conclusions: This study provided practitioners in Korean medicine (KM) a core information about the recent changes in CFS-related perspectives. This review would be helpful for KM-derived researches or therapeutics development for CFS.

• 대한암한의학회지
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• 제13권1호
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• pp.43-54
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• 2008

Objectives: The purpose of this study is to suggest better directions in experimental researches about finding new drug derived from herbs in South Korea. Methods: We investigated available manuscripts on anti-lung cancer herbal extracts which is used in South Korea by using available electric library, and made diagrams. Results: Many herbs are used in treatment of lung cancer based on traditional oriental medical theory. In Korea, researches for this field have been activated since 2000. But we haven't found the substance showing remarkable anti-tumor effect on lung cancer. And many of the experiment have been designed similar way and also have similar weak points in explanation about the apoptotic mechanism. Conclusions: From this results, we have found 10 herbs, 4 pharmacopunctures and 13 herbal decoctions to be conducted experimental studies for lung cancer from 2000 to 2008 in South Korea.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.310-315
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• 2009

Large hospitals such as medical centers provide not only medical services, but also carry the responsibilities for emergency refuges, medical researches and education. The function of large hospitals is as important as other infrastructure systems such as highways, bridges, and utilities. When disasters occur, the hospitals have to provide emergency medical services for victims and support the patient's needs of health. In order to keep a smooth operation of hospitals, the maintenance management of hospital buildings should be carefully investigated. However, there are few researches focused on maintenance management issues of hospital buildings. This paper investigated the National Taiwan University Hospital (NTUH) and established a maintenance cost database. The NTUH is the best-known and most high-renowned medical center in Taiwan in which more than 4,000 employees serving approximately 2,000 in-patients and 7,000 out-patients daily. The data were collected from the NTUH which consisted of 16,228 maintenance records in the past ten years. This paper analyzed these data to obtain various characteristics of maintenance records, and revealed the key items of maintenance cost for large hospital buildings, which can provide the facility manager of hospital buildings to execute a proper maintenance policy for hospital buildings.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1999년도 제51차 추계 학술대회 연제집
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• pp.83-84
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• 1999