• Journal of the Korean Society of Safety
• /
• 제30권5호
• /
• pp.74-79
• /
• 2015

The purpose of this study is to find out its effect on changes in the joint angle and the success rate of cardiopulmonary resuscitation by conducting cardiopulmonary resuscitation (CPR) when wearing and not wearing PPE (personal protective equipment) targeting 20 paramedics with more than 5 years of experience. The subjects carried out CPR in 30:2 for 4 minutes and collected images were digitized by Kwon3D XP Software Package(Version 4.0) and then data were obtained. Data, which were collected by analyzing the motion when starting in one cycle, when pressing to the maximum, in the final position (relaxed), were analyzed by using SPSS 18.0. In conclusion, during CPR, the angle of the both shoulder joints was not significant (p>.05) and the angle of the right elbow joint was reduced in all positions and was statistically significant (p<.05) and the angle of the left was significantly reduced in the maximum pressure posture and the final position (p>.05). In the case of the trunk, the angle increased statistically significantly at all stages (p<.01, p<.001). Also, during CPR, the average compression rate was significantly reduced after wearing PPE (p<.05) and average hand escape time by cycle increased statistically significantly (p<.05) but chest compression execution rate at the correct depth did not show any significant difference between the two groups (p>05).

• Journal of the Korea Society of Computer and Information
• /
• 제23권11호
• /
• pp.143-149
• /
• 2018

The purpose of this study is to propose a management method to maintain the pleasant indoor air quality of the dental clinic by measuring and analyzing the indoor air quality of the dental clinic. The measurement was conducted in two rooms, a lobby where many residents stay in the reception room for waiting for medical treatment, and a VIP room where treatment activities are mainly performed. Measurement items are Temperature, Humidity, $CO_2$, CO, $NO_2$, $CH_2O$, VOC, $PM_{10}$ and measurement were taken on April 27, 2018. As a result of analyzing the temperature and humidity of the dental clinic, it was analyzed that the average indoor temperature was maintained at $25^{\circ}C$ and the humidity was kept at around 50%, maintaining proper indoor temperature and humidity environment. $CO_2$ was 855ppm in the VIP Room, which satisfied the maintenance standard. In the case of the lobby, it was analyzed to be 1,160ppm, which exceeded the maintenance standard and it is judged that the carbon dioxide generated by the respiration of the people staying in the lobby is the main reason. The mean concentration of formaldehyde in the VIP room was analyzed as $436{\mu}g/m^3$, exceeding the maintenance standard, and $2,100{\mu}g/m^3$ for the VOC exceeded the recommended standard. It was analyzed that the concentration was relatively higher due to the use of disinfectant and other drugs. The mean concentration of PM-10 in the lobby was analyzed as $65{\mu}g/m^3$ and it was analyzed that it satisfied the maintenance standard. To maintain a pleasant indoor air quality in a dental clinic it is necessary to minimize the effects of formaldehyde, VOC, $CO_2$ in the VIP rooms and lobby. For this purpose, the entire ventilation system and air purification system of the dental clinic should be installed. In case of the VIP room, local exhaust ventilation should be installed and workers should wear personal protective equipment.

• Safety and Health at Work
• /
• 제7권4호
• /
• pp.317-321
• /
• 2016

Background: This study was conducted with aim of providing an overview of the current status of occupational health services and identifying the most common harmful agents at workplaces of Iranian self-employed enterprises (Nano-Scale Enterprises). Methods: A cross-sectional study was performed among a random sample including 1,758 employees engaging in self-employed enterprises with 5 and less employees. Results: Coverage of occupational health surveillance was very poor, annual health examinations were been conducted only for 64 (3.64%) of males and 31 (1.76%) of females, and occupational health trainings were not included of the services at all. Personal Protective Equipment were available in 462 (26.3%) of the enterprises. only in 0.4% of the enterprises working processes were been equipped by a local exhaust ventilation system. Difficult postures were the most common (81.5%) adverse working conditions. Conclusion: This study revealed a poor level of the implementation of occupational health services in Iranian self-employed enterprises. Based on the findings, providing basic training on the occupational health, more enforcing in conduction of health examinations and providing PPE, and taking appropriate strategies aimed at eliminating or minimizing work environment harmful agents are the major factor that should be considered to improve the level of occupational health services among the studied enterprises.

• Safety and Health at Work
• /
• 제14권1호
• /
• pp.118-123
• /
• 2023

Background: Chronic exposure to silica is related with the provocation of an inflammatory response and oxidative stress mechanism. Vitamin D has multiple benefits in biological activities particularly respiratory system disease. Method: In this research, 20 male Wistar rats were randomly allocated into four groups (5 rats /group) as follow: Group1 received saline as (negative control) group. The group 2 received a single IT instillation of silica (positive control) group; the group 3 was co-administrated with single IT silica and Vitamin D (20 mg/kg/day) daily for a period of 90 days. The rats of group 4 received Vitamin D daily for a period of 90 days. Results: Silica significantly increased serum and lung total Oxidant Status (TOS). Meanwhile, silica reduced serum and lung total antioxidant capacity (TAC), GSH and tumor necrosis factor-α (TNF-a). Vitamin D treatment meaningfully reversed oxidative stress, antioxidants status and inflammatory response. Also, Vitamin D improved histopathological changes caused by silica. Conclusion: These findings indicate that Vitamin D exerts protective effects against silica-induced lung injury. It seems that Vitamin D has potential use as a therapeutic object for silica induced lung injure.

• Proceedings of the Korean Society for Applied Microbiology Conference
• /
• 한국미생물생명공학회 2003년도 2003 Annual Meeting, BioExhibition and International Symposium
• /
• pp.55-62
• /
• 2003

The mucosal immune system provides a first line of defense against invasion of infectious agents via inhalation, ingestion and sexual contact. For the induction of protective immunity at these invasion sites, one must consider the use of the CMIS, which interconnects inductive tissues, including PP and NALT, and effector tissues of the intestinal, respiratory and genitourinary tracts. In order for the CMIS to induce maximal protective mucosal immunity, co-administration of mucosal adjuvant or use of mucosal antigen delivery vehicle has been shown to be essential. When vaccine antigen is administered via oral or nasal route, antigen-specific Th 1 and Th2 cells, cytotoxic T lymphocytes(CTLs) and IgA B cell responses are effectively induced by the CMIS. In the early stages of induction of mucosal immune response, the uptake of orally or nasally administered antigens is achieved through a unique set of antigen-sampling cells, M cells located in follicle-associated epithelium(FAE) of inductive sites. After successful uptake, the antigens are immediately processed and presented by the underlying DCs for the generation of antigen-specific T cells and IgA committed B cells. These antigen-specific lymphocytes are then home to the distant mucosal effector tissues for the induction of antigen-specific humoral(e.g., IgA) and cell-mediated (e.g., CTL and Th1) immune responses in order to form the first line of defense. Elucidation of the molecular/cellular characteristics of the immunological sequence of mucosal immune response beginning from the antigen sampling and processing/presentation by M cells and mucosal DCs followed by the effector phase with antigen-specific lymphocytes will greatly facilitate the design of a new generation of effective mucosal antigen-specific lymphocytes will greatly facilitate the design of a new generation of a new generation of effective mucosal adjuvants and of a vaccine deliver vehicle that maximizes the use of the CMIS.

• Natural Product Sciences
• /
• 제15권4호
• /
• pp.185-191
• /
• 2009

Intestinal epithelial cells (IEC) play an important role in the mucosal immune system. IEC-derived mediators of inflammatory cascades play a principal role in the development of colon inflammation. The aim of this study was to investigate the inhibitory effect of aqueous extracts of Schizandra chinensis fruits (SC-Ex) on the production of inflammatory mediators by the human colonic epithelial cells. HT-29 cells were stimulated with dextran sulfate sodium in the presence or absence of SC-Ex to examine the cytoprotection and production of IL-8 and reactive oxygen species (ROS). It was shown that dextran sulfate sodium (DSS) caused the reduction of cell viability and production of IL-8 and ROS in DSS-treated HT-29 cells. We observed that the treatment of SC-Ex protected significantly cell proliferation from DSS-induced damage in dose-dependent manner. SC-Ex (10 and 100 ${\mu}g$/ml) also suppressed DSS-induced production of IL-8 mRNA and protein. Moreover, DSS-induced ROS production was inhibited markedly by the treatment of 100 ${\mu}g$/ml SC-Ex. These results suggest that SC-Ex has the protective effects on DSS-induced cell damage and the release of inflammatory mediators in the intestinal epithelial cells.

• Korean Journal of Pharmacognosy
• /
• 제50권3호
• /
• pp.175-184
• /
• 2019

Mast cells are crucial as effector cells in the immediate-type allergic reaction. Lentinus edodes has been the popular edible mushroom in oriental countries and reported to have immunomodulatory, anti-tumor, anti-atherogenic, anti-viral, and anti-allergic activities. However, the roles of L. edodes in mast cell-mediated anaphylactic reaction have not been fully elucidated. In this research, we have demonstrated the effects of the methanol extract of L. edodes (MELE) on mast cell-mediated anaphylaxis-like and anaphylactic reactions. MELE suppressed systemic anaphylaxis-like reaction, plasma histamine levels, and ear swelling response in mice treated with compound 48/80. MELE also suppressed passive systemic and cutaneous anaphylaxis mediated by anti-dinitrophenyl IgE. In accordance with these findings, MELE dose-dependently decreased histamine release from RPMC evoked by compound 48/80 or the antigen-antibody reaction. To clarify the mechanism of degranulation system, intracellular cAMP levels as well as calcium influx in RPMC was evaluated. In compound 48/80-treated RPMC, MELE blocked calcium uptake into the cells. In addition, MELE elevated the intracellular cAMP content and significantly attenuated compound 48/80-induced cAMP reduction in RPMC. Taken together, we propose the clinical use of MELE in mast cell-mediated immediate-type allergic diseases.

• Clinics in Shoulder and Elbow
• /
• 제25권4호
• /
• pp.282-287
• /
• 2022

Background: Muscular forces drive proximal humeral fracture deformity, yet it is unknown if arm position can help mitigate such forces. Our hypothesis was that glenohumeral abduction and humeral internal rotation decrease the pull of the supraspinatus and subscapularis muscles, minimizing varus fracture deformity. Methods: A medial wedge osteotomy was performed in eight cadaveric shoulders to simulate a two-part fracture. The specimens were tested on a custom shoulder testing system. Humeral head varus was measured following physiologic muscle loading at neutral and 20° humeral internal rotation at both 0° and 20° glenohumeral abduction. Results: There was a significant decrease in varus deformity caused by the subscapularis (p<0.05) at 20° abduction. Significantly increasing humeral internal rotation decreased varus deformity caused by the subscapularis (p<0.05) at both abduction angles and that caused by the supraspinatus (p<0.05) and infraspinatus (p<0.05) at 0° abduction only. Conclusions: Postoperative shoulder abduction and internal rotation can be protective against varus failure following proximal humeral fracture fixation as these positions decrease tension on the supraspinatus and subscapularis muscles. Use of a resting sling that places the shoulder in this position should be considered.

• Proceeding of Spring/Autumn Annual Conference of KHA
• /
• 한국주거학회 2005년도 추계학술대회 논문집
• /
• pp.371-374
• /
• 2005

As the aging of this society, instead of growing numbers old protective functions of families decreased according to increasing tendency of nuclear families, increasing rates of females' participation of economic activities. Now, the problem of supporting the old is in need of social supporting system the cope with this are based on these factors are like this: 1) It is necessarily the instruction of medical welfare service. 2) The overlapped service is avoided and the service of specialized. 3) Most of the welfare service institution is Seoul and local city hall, so it needs the institution is transferred. 4) It needs the increase the number of home helper. 5) When the service is offered, the government must considers finance, elderly health condition and preference. 6) It needs the department for the welfare service for the old who stay at home.

• Journal of Korean society of Dental Hygiene
• /
• 제20권6호
• /
• pp.875-888
• /
• 2020

Objectives: The purpose of this study was to investigate the infection control system and actual conditions according to the type of dental medical institution. Methods: From April 1st to May 10th, 2020, dental institutions were recruited through stratified random sampling. Each item constituting the infection control system by dental institution type was analyzed using the chi-square test and fisher's exact test. Results: The infection control system and operation level of each dental institution type was 89.0 points for university-general hospitals, 75.6 points for dental hospitals, and 34.4 points for dental clinics. The environment management levels were 76.1, 72.5, 73.0, and 74.0 points for university-general hospitals, similar to 77.2, 75.1, 71.0, and 73.8 points for dental hospitals, while dental clinics had 61.1, 40.0, 37.0, and 45.6 points. Prevention and management of staff infection exposure, wearing personal protective equipment, and hand hygiene levels were 90.7, 75.5, 88.5 points for university-general hospitals, 79.8, 79.5, 80.4 points for dental hospitals, and 50.2, 88.0, 61.5 points for dental clinics, respectively. Conclusions: Efforts are required to bring about improvement in the areas of insufficient infection control in order to raise the overall infection control levels, especially the management of dental clinics is urgently needed.