• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.14 no.1
• /
• pp.275-279
• /
• 2014

Due to a modern medical technology developement and the stability of social welfare policy, the current population of old person in Korea reaches to 550 million with the increasing elderly population rate(11.8%). But the living standard of elderly people does not meet to their needs of convenience on the proportion of the percentage of elderly people. Accordingly, this study mainly focuses on the research to find various advanced IT technologies to make elderly people more convient to use. Advanced IT industry makes it possible the convinence of elderly people using NFC, Wi-Fi, cardiac measurement technology.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.10 no.1
• /
• pp.9-15
• /
• 2005

A bioartificial liver (BAL) is a medical device entrapping living hepatocytes or immortalized cells derived from hepatocytes. Many efforts have already been made to maintain the functions of the hepatocytes in a BAL device over a long term. However, there is still some uncertainty as to their efficacy. and their limitations are unclear. Therefore, it is important to quantitatively evaluate the metabolic functions of a BAL. In previous studies on in vitro BAL devices, two test methods, an initial bolus loading and constant-rate infusion plus initial bolus loading, were theoretically carried out to obtain physiologic data on drugs. However, in the current study, the same two methods were used as a perfusion model and derived the same clearance characterized by an interrelationship between the perfusate flow rate and intrinsic clearance. The interrelationship indicated that the CL increased with an increasing perfusate flow rate and approached its maximum value, i.e. intrinsic clearance. In addition, to set up an in vivo BAL system, the toxic plateau levels in the BAL system were calculated for both series and parallel circuit models. The series model had a lower plateau level than the parellel model. The difference in the toxic plateau levels between the parallel and series models increased with an increasing number of BAL cartridges.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.12
• /
• pp.4859-4862
• /
• 2015

Background: Fatigue, stress and pain are common symptoms among cancer patients, affecting the quality of life. The purpose of the present study was to determine the effect of distant Reiki on pain, anxiety and fatigue in oncology patients. Materials and Methods: Participants in the control group received usual medical and nursing care during their stay. The intervention group received usual care plus five distant Reiki sessions, one each night for 30 min. A face to face interview was performed and patient personal and illness related characteristics were evaluated using the Patient Characteristics form. Pain, stress and fatigue were evaluated according to a numeric rating scale. Results: The experimental group was predominantly composed of women (71.4%), married individuals (40%), and primary school graduates (40%). The control group was predominantly male (72.7%), married (60%), and primary school graduates (60%). The control group demonstrated greater levels of pain (p=0.002), stress (p=0.001) and fatigue (p=0.001). The Reiki group pain score (p <0.0001), stress score (p <0.001) and fatigue score were also significantly lower. Conclusions: The results of this study indicate that Reiki may d ecreasepain, anxiety and fatigue in oncology patients.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.2
• /
• pp.561-568
• /
• 2014

Background: The skin is the largest body organ that regulates excretion of metabolic waste products, temperature, and plays an important role in body protection against environmental physical and chemical, as well as biological factors. These include agents that may act as oxidants or catalysts of reactions producing reactive oxygen species (ROS), reactive nitrogen species (RNS), and other oxidants in skin cells. An increased amount of the oxidants, exceeding the antioxidant defense system capacity is called oxidative stress, leading to chronic inflammation, which, in turn, can cause collagen fragmentation and disorganization of collagen fibers and skin cell functions, and thus contribute to skin diseases including cancer. Moreover, research suggests that oxidative stress participates in all stages of carcinogenesis. We report here a summary of the present state of knowledge on the role of oxidative stress in pathogenesis of dermatologic diseases, defensive systems against ROS/RNS, and discuss how physical activity may modulate skin diseases through effects on oxidative stress. The data show duality of physical activity actions: regular moderate activity protects against ROS/RNS damage, and endurance exercise with a lack of training mediates oxidative stress. These findings indicate that the redox balance should be considered in the development of new antioxidant strategies linked to the prevention and therapy of skin diseases.

• The Journal of Asian Finance, Economics and Business
• /
• v.7 no.9
• /
• pp.659-672
• /
• 2020

The outbreak of a recent strain of Coronavirus, known as 'COVID-19', has spread sharply from China across the globe, resulting in a dramatic recession in the global economy. This uncertainty has therefore negatively influenced the business perspective and the various formulated strategies that may not considered such [extreme] circumstances. Using baseline analysis and archival data, this paper reports some of the major implications of COVID-19 on global business and strategy and puts forward suggested research agenda as potential future directions for organizations. In order to survive and remain sustainable, this paper argues that businesses need to revisit their strategies during current COVID-19 crises from three perspectives, including supporting human resources financial commitment, forming cross-functional teams and connecting with their supply chains, as well as investing in corporate social responsibility and doubling down efforts with regard to partnerships. The study also represents a preliminary analysis to the implications of COVID-19 on the business and strategies across the globe and is considered the first such in the field of business, as to date all research papers on COVID-19 have been published in medical-related journals. Directions for future research are also proposed at the end of this study.

• Communications for Statistical Applications and Methods
• /
• v.21 no.6
• /
• pp.471-486
• /
• 2014

This study introduces a new type of symbolic data, a candle chart-valued time series. We aggregate four stock indices (i.e., open, close, highest and lowest) as a one data point to summarize a huge amount of data. In other words, we consider a candle chart, which is constructed by open, close, highest and lowest stock indices, as a type of symbolic data for a long period. The proposed candle chart-valued time series effectively summarize and visualize a huge data set of stock indices to easily understand a change in stock indices. We also propose novel approaches for the candle chart-valued time series modeling based on a combination of two midpoints and two half ranges between the highest and the lowest indices, and between the open and the close indices. Furthermore, we propose three types of sum of square for estimation of the candle chart valued-time series model. The proposed methods take into account of information from not only ordinary data, but also from interval of object, and thus can effectively perform for time series modeling (e.g., forecasting future stock index). To evaluate the proposed methods, we describe real data analysis consisting of the stock market indices of five major Asian countries'. We can see thorough the results that the proposed approaches outperform for forecasting future stock indices compared with classical data analysis.

• International Journal of Industrial Entomology and Biomaterials
• /
• v.5 no.1
• /
• pp.123-126
• /
• 2002

More than three hundred million men in the world are suffering from erectile dysfunction. Korean ancient medical records say that the unmated male silkworm moth is effective in strengthening men's vitality, but no scientific examination has preyed its clinical efficacy. Currently, silkworm moths are not allowed for food-stuff. Thus, we selected silkworm of 14-days-after-metamorphosis, at which external morphology possesses that of pupae, but internal component is that of moths. To obtain the reliable source of unmated male silkworm moth, we used the sex-limited silkworm breed with larval marking. The body marker allows casual separation of sex during larval period, preventing mating right after emergence from cocoon. Using the extract prepared with the pupae of 14-days-after-metamorphosis, we investigated the tonic effect of the extract on the rat fed the extract for three weeks. The results showed that the testosterone levels in serum increased maximum by 19%, that of testicle increased maximum by 200%, and athletic endurance of the rats rose by 6%, suggesting positive tonic effect of the pupae prepared at the stage of 14 days after metamorphosis.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1998.11a
• /
• pp.22-26
• /
• 1998

The medicinal plants have been used as drugs for thousands of years and many of them are used in traditional medicines. How long are these medicinal plants used as drugs\ulcorner Ebers papyrus (BC 1550) is one of the oldest documents which described more than 700 kinds of herbal drugs. Some of herbal medicines described in the papyrus are familiar and ‘Opium’ is a good example. Some of the drugs described in the papyrus are hardly recognized as drugs by the standard of present day. We can trace back the history of medicinal plants from quite different approach. The investigations on group behavior of chimpanzees in Africa by ‘The Primate Institute of Kyoto University’ has revealed that chimpanzees suffered illness take specific plants which are not taken as daily food stuff. The chemical analysis clarified that the plants contain very bitter constituents and suggested that chimpanzees take medicinal plants to cure their illness. It is worth to note that young chimpanzees just learn what elder ones take when they suffer illness, but elders never teach to their children! It is no doubt that the chimpanzee's medicinal plants were found by random, and try and error screening. The medicinal plants found in this study have been used as herbal medicines by the peoples in the region.

• Applied Microscopy
• /
• v.29 no.3
• /
• pp.377-382
• /
• 1999

Osteoporosis means a deficiency in the amount of bone tissue in the skeleton or part of the skeleton. Osteoporosis is a lesion, not a specific disease. 'Osteoporotic' describes the slate of a bone or skeleton at a given time. Osteoporosis may be diagnosed subjectively by visual appraisal, or objectively by measurement of radiographs, sawn bones, or microscopic sections. This study was carried out to make clear of the influence of ovariectomy on time course of fibular osteoporosis in rats. Seven weeks after ovariectomy, osteoporosis was evident, when the size of the bone marrow cavities significantly increased and the width from the bone marrow cavity and cortex significantly decreased than normal.

• Animal cells and systems
• /
• v.8 no.2
• /
• pp.111-115
• /
• 2004

The epidermis of the mudskipper, Periophthalmus modestus, consists of three layers- the outermost layer, middle layer and stratum germinativum. Extensive fine blood capillaries are present near the superficial layer of epidermis and outermost layer in five fins and a sucking disc. The diffusion distance between the vascular capillaries and the surface of epidermis ranged from 3.6 to 10.9${\mu}$m: 3.6 ${\mu}$m in the sucking disc, 10.9 ${\mu}$m in the anal fin and 4.6 to 5.0 ${\mu}$m in the two dorsal fins. Rate of the surface area of respiratory epithelium, the surface area of the fine blood capillaries occupied per surface area of epidermis in 0.1mm, is 3.7 to 4.4% in two dorsal fins and 1.1% in the anal fin. The middle layer is simpler in structure consisting of small or voluminous cells swollen by epidermal cells, and this layer appeared web-like. Well-developed lymphatic spaces containing lymphocytes existed in the stratum germinativum. The five fins and sucking disc had no epidermal glands.