• Journal of Acupuncture Research
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• 제33권1호
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• pp.1-7
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• 2016

Objectives : This study was conducted to analyze the single dose toxicity of Mecasin (Gami-Jakyak Gamcho buja Decoction) herbal acupuncture administered in the vein of Sprague-Dawley rats. Methods : All experiments were performed at the Medvill, an institution licensed to conduct nonclinical studies, under the Good Laboratory Practice (GLP) regulations. Sprague-Dawley rats were chosen in this pilot study. In the experiment, Sprague-Dawley rats were divided into four groups of five male and five female animals per group. Doses of Mecasin herbal acupuncture, at 0, 500, 1,000, and 2,000 mg/kg, were given to the experimental groups, and a dose of normal saline solution, at 2 ml/kg, was administered to the control group. Mecasin herb acupuncture and normal saline were injected into the vein at once, and we observed mortality, clinical signs, weights, and gross findings for 14 days after injection. This study was conducted under the approval of the Institutional Animal Ethics Committee. Results : There is no death or abnormality in any of the four groups. All groups put on weights favorably. There are no significant gross findings in necropsy examinations. Conclusions : The above results showed that intravenous injection of 500-2,000 mg/kg of Mecasin herb acupuncture did not cause any changes in weight or, in the results of necropsy examinations, in mortalities. Therefore, the toxicity of Mecasin herb acupuncture was not confirmed, and the presumptive lethal dose of Mecasin herb acupuncture was higher than 2,000 mg/kg. The outcomes suggest that treatment with Mecasin herbal acupuncture is relatively safe. Further evaluations on this subject are needed to yield more concrete evidence.

• 의료법학
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• 제10권2호
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• pp.455-492
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• 2009

(Background) Recent biotechnological breakthroughs are shedding new lights on various ethical and legal issues about human biological material. Since Rudolph Virchow, a German pathologist, had founded the medical discipline of cellular pathology, issues centering around human biological materials began to draw attention. The issues involving human biological materials were revisited with more attention along with series concerns when the human genome map was finally completed. Recently, with researches on human genes and bioengineering reaping enormous commercial values in the form of material patent, such changes require a society to reassess the present and future status of human tissue within the legal system. This in turn gave rise to a heated debate over how to protect the rights of material donors: property rule vs. no property rule. (Debate and Cases) Property rule recognizes the donors' property rights on human biological materials. Thus, donors can claim real action if there were any bleach of informed consent or a donation contract. Donors can also claim damages to the responsible party when there is an infringement of property rights. Some even uphold the concept of material patents overtaking. From the viewpoint of no property rule, human biological materials are objects separated from donors. Thus, a recipient or a third party will be held liable if there were any infringement of donor's human rights. Human biological materials should not be commercially traded and a patent based on a human biological materials research does not belong to the donor of the tissues used during the course of research. In the US, two courts, Moore v. Regents of the University of California, and Greenberg v. Miami Children's Hospital Research Institute, Inc., have already decided that research participants retain no ownership of the biological specimens they contribute to medical research. Significantly, both Moore and Greenberg cases found that the researcher had parted with all ownership rights in the tissue samples when they donated them to the institutions, even though there was no provision in the informed consent forms stating either that the participants donated their tissue or waived their rights to ownership of the tissue. These rulings were led to huge controversy over property rights on human tissues. This research supports no property rule on the ground that it can protect the human dignity and prevent humans from objectification and commercialization. Human biological materials are already parted from human bodies and should be treated differently from the engineering and researches of those materials. Donors do not retain any ownership. (Suggestions) No property rule requires a legal breakthrough in the US in terms of donors' rights protection due to the absence of punitive damages provisions. The Donor rights issue on human biological material can be addressed through prospective legislation or tax policies, price control over patent products, and wider coverage of medical insurance. (Conclusions) Amid growing awareness over commercial values of human biological materials, no property rule should be adopted in order to protect human dignity but not without revamping legal provisions. The donors' rights issue in material patents requires prospective legislation based on current uncertainties. Also should be sought are solutions in the social context and all these discussions should be based on sound medical ethics of both medical staffs and researchers.

• 의료법학
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• 제19권1호
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• pp.81-111
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• 2018

최근 우리나라에서는 연속적으로 발생한 환자안전사건으로 인해 환자안전에 대한 사회적 관심이 높아졌다. 더불어 환자안전사건 발생 후 의료인 및 의료기관의 대응방식이 논란이 되면서, 사과법 및 디스클로져법 도입의 필요성이 제기되고 있다. 본 연구에서는 미국의 사과법과 디스클로져법 내용을 분석하고, 우리나라의 입법 움직임에 대하여 비판적으로 검토하고자 한다. 먼저 사과법은 의료인 등이 환자측에게 불편감, 통증, 손상, 사망 등에 대해 사과나 위로, 공감 등을 표하는 경우, 사과 등의 표현은 민사재판 및 행정절차에서 법적인 증거로 사용할 수 없도록 하는 것을 그 주요 내용으로 한다. 사과법은 실수, 오류, 잘못, 책임, 법적 책임의 표현과 같은 규범적 평가요소를 증거법의 보호 범위에 포함하는지 여부에 따라 '완전한 사과법'과 '부분적 사과법'으로 구분된다. 한편, 디스클로져법은 의료기관이 심각한 위해가 발생한 사건 등에 있어 사건의 공개, 발생원인, 보상계획, 재발방지대책 등에 관하여 환자 측과 소통하는 것을 법률상 강제하거나 자율적으로 유도하는 것을 그 주요 내용으로 한다. 한편, 최근 우리나라에서도 환자안전사고에 관한 관심이 증폭되고, 의료인 측과 환자측의 의사소통의 중요성이 인식되면서, 위와 같은 미국의 사과법 또는 디스클로져법을 수용한 "환자안전법" 개정법률안이 국회에 제출되기도 하였다. 본 연구에서는 미국의 사과법 및 디스클로져법의 분석을 토대로 위 개정법률안의 내용을 비판적으로 검토함으로써 향후의 입법방향에 시사점을 제시하고자 한다.

• 대한약침학회지
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• 제18권1호
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• pp.63-71
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• 2015

Objectives: This study was carried out to analyze the single-dose toxicity of Eun-Bi San pharmacopuncture injected into the muscle of Sprague-Dawley (SD) rats. Methods: All experiments were performed at Biotoxtech, an institution certified to conduct non-clinical studies under the Good Laboratory Practice (GLP) regulations. Six week old SD rats reared by ORIENTBIO were chosen for this pilot study. The reason SD rats were chosen is that they have been widely used in safety tests in the field of medicine, so the results can be easily compared with many other databases. The Eun-Bi San pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (KPI, K-GMP). The constituents of the Eun-Bi San pharmacopuncture are Angelicae gigantis radix, Strychni semen and Glycyrrhizae radix. These were extracted at low temperature and low pressure in an aseptic room at the KPI. Doses of Eun-Bi San pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. This study was performed under the approval of the Institutional Animal Ethics Committee of Biotoxtech Co., Ltd. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To determine if abnormalities existed in any organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The results of this study suggest that treatment with Eun-Bi San pharmacopuncture is relatively safe and that its clinical use may be beneficial. Further evaluations and studies on this subject will be needed to provide more concrete evidence in support of these conclusions.

• 기본간호학회지
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• 제9권1호
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• pp.76-85
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• 2002

Purpose: This study has been designed to identify attitudes to euthanasia held by Korean nurses. Method: Data were collected through a survey, and the participants in the study were 234 Korean nurses. Convenience sampling method was used and analysis of the data was done with SPSS PC for descriptive statistics, t-test and ANOVA. Results : 1. The mean score for euthanasia was 2.80. and the sub dimension mean scores were, patients' rights. 3.24, quality of life, 2 78, respect for life, 2.68, medical ethics, 2.50. 2. With respect to the general characteristics of participants there were statistically significant difference in total score according to religion (P= .01), and degree of influence of religion on behavior (P= .00). 3. There were statistically significant difference in score of quality of life according to religion (P= .04), degree of influence of religion on behavior (P= 00), decisions in euthanasia (P=.04), and legal permission (P= .04). 4. There was statistically significant difference in score of patient's right according to legal permission (P = .04). 5 There were statistically significant difference in the score of respect for life according to religion (P= .00), degree of influence of religion on behavior (P= .00), decision in euthnasia (P= .00), and legal permission (P= .00).

• 한국간호교육학회지
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• 제14권2호
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• pp.167-175
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• 2008

Purpose: The purpose of this study was to explore the structure and characteristics of male college nursing students' personality-based career attitudes. Method: The Q-methodology was used to identify factors in male nursing students' personality-based career attitudes. A Q sample was collected from literature reviews (Kim & Kim, 2005). The subjects consisted of 30 male nursing students. Result: The results of the study show that male nursing students can be categorized into four types. The five factors extracted all had eigen values greater than 1.0 and explained approximately 50.84% of the variation in responses (32.62, 7.59, 5.70 and 4.93% respectively). The categories were labeled 'Repair intention style', 'Belief intention style', 'Stability intention style', and 'Self-regulation intention style'. Conclusion: Through a process that analyzes subjective structure, male nursing students' personality based career attitudes create occupational consciousness, professional accomplishment and professional ethics as a nursing profession. Content of curriculum and development of a reasonable and realistic course consultation program should be done.

• 간호행정학회지
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• 제12권1호
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• pp.131-139
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• 2006

Purpose: This study was carried out to understand the degree of moral distress of nurses and to provide scientific data for searching measures to efficiently manage their moral distress. Method: The survey was conducted with 302 nurses at the general hospital in City D by using the self-report type of questionnaire composed of 66 questions of 5-point Likert scale in four dimensions. Result: The mean scores of moral distress of nurses showed higher than average in all four dimensions: $80.54{\pm}14.82$ of 150 in the situational dimension, $52.99{\pm}9.98$ of 90 in the cognitive dimension, $13.30{\pm}2.85$ of 25 in the behavioral dimension, and $48.06{\pm}7.76$ of 65 in the emotional dimension. In addition, moral stress of each factor in the situational area showed $34.20{\pm}7.27$ in negative medical behavior, $10.98{\pm}2.53$ in lack of respect for autonomy of patients, excessive economic burden $10.86{\pm}2.94$, $7.40{\pm}1.89$ in irrational organizational administration and $17.10{\pm}3.50$ in negative nursing behavior. Conclusion: It is necessary to develop the intervention program to help nurses to reduce their moral distress since its degree showed considerably high.

• 대한물리의학회지
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• 제11권3호
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• pp.59-63
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• 2016

PURPOSE: The purpose of the present study is to examine the effects of sole Pilates based breathing on the thicknesses of the abdominal muscles. METHODS: Twenty adults aged in their 20-30s were randomly selected. The selection criteria were those who had no medical history of pain due to musculoskeletal system, neurologic, or orthopedic diseases within six months before the selection. The thicknesses of the abdominal muscles (the transversus abdominis muscle, internal oblique abdominal muscle, and external oblique abdominal muscle) of the subjects were measured using ultrasonography before and after Pilates breathing. The study was approved by the research ethics committee of the Catholic University of Pusan. RESULTS: After Pilates based breathing, the thicknesses of the transversus abdominis muscle, the internal oblique abdominal muscle, and the external oblique abdominal muscle increased significantly. In particular, the thickness increase rate of the transversus abdominis muscle was shown to be the highest. CONCLUSION: Sole Pilates based breathing is expected to be effective for the improvement of trunk stability through strengthening of abdominal muscles, because it induces the coordinated contraction of the transversus abdominis muscle and other abdominal muscle. It will be need the Longitudinal study for identify to long term effects of Pilates based breathing.

• 지역사회간호학회지
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• 제22권1호
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• pp.33-44
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• 2011

Purpose: This study examined the characteristics and service utilization of home nursing care beneficiaries under the Korean Long-Term Care Insurance (LTCI). Methods: We used assessment data and claim data of National Health Insurance Corporation from July to August 2008. Data were composed of subjects who were the beneficiaries of home nursing care. Results; A total of 634 subjects were analyzed. Of the subjects, 57.1% were 75 years and over. The average score of nursing care need was only 0.71 and the percentage of those whose nursing care need score was zero was 58.0%. More than half of the subjects had partially dependent musculoskeletal conditions, and 75.5% had two or more comorbidities. A third of them usedonly home nursing care, and another third used both home nursing care and general home care at the same time. Those who needed sore care used the largest home nursing care benefits. Conclusion: Home nursing care of LTCI performs community-based healthcare services under LTCI. Throughout the past two years, however, it has not been active. Understanding the characteristics of its users is important in order to develop effective strategies for activating home nursing care.

• 보건교육건강증진학회지
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• 제11권2호
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• pp.146-159
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• 1994

The conecpt of hospice care for the terminally ill is a development of relatively modern times, although it has its origins in antiquity. The hospice will be able to handle progressively more and more patient, to the limit of its resources. The purposes of this study were to review of demand and issues of the hospice care programes and to recommand the hospice care approaches in south Korea that using the book-review method. At this point, although at present there is a general unawareness of hospice throughout Korean society, the public will become gradually aware of hospice. This will thus aid the development of hospices. Awareness will come about because of the educational efforts of medical schools, nursing schools, allied health training programs, practicing hospice care giver, universities, and others interested in hospice education. At present, there are many issues of the hospice care program that are hospice resources problems of manpower, facilities, finances, and cost of hospice services, quality of care, and ethics. Additional studies are needed to determine the most efficacious organizational hospice models for varying conditions. They will insist upon reasonable regulatory agency regulations that will promote the hospice idea and. permit adequate remuneration for services provided. More research is needed on health professionals', patients', and others' attitudes towards death.