• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.81-85
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• 2016

Globally, the burden of breast cancer (BC) continues to increase. BC related lymphedema (BCRL) is currently non curable and as a life time risk it affects at least 25% of BC patients. Knowing more about BCRL and appropriate control of its modifiable risk factors can improve quality of life (QOL) of the affected patients. In this case control study to detect factors, 400 women with BCRL (as the case group) and 283 patients with BC without lymphedema (as the control group) that were referred to Shiraz University of Medical Sciences affiliated BC clinic center were assessed. The data were analyzed in SPSS. The mean age of the case group was $52.3{\pm}11.0years$ and of the control group was $50.1{\pm}10.9years$. In patients with BCRL, 203(50.7%) had left (Lt) side BC and in non- lymphedema group 151 (53.3%) had Lt side BC. Out of all BCRL patients, 204 (51%) had lymphedema in all parts of their affected upper extremities, 100 (25%) had swelling in the arm and forearm and 23 (5.7%) had edema in both the upper extremity and trunk. Edema, heaviness, concern about changing body image, pain and paresthesia were the most common signs/symptoms among patients with BCRL. In BCRL patients, the difference of circumference between the affected upper limb and non-affected limb was $4.4{\pm}2.5cm$ and the difference in volume displacement was $528.7{\pm}374.4milliliters$. Multiple variable analysis showed that moderate to severe activity (OR; odds ratio =14, 95% CI :2.6-73.3), invasiveness of BC (OR =13.7, 95% CI :7.3-25.6), modified radical mastectomy (OR=4.3, 95% CI :2.3-7.9), BMI =>25 (OR=4.2, 95% CI :2-8.7), radiotherapy (OR=3.9, 95% CI :1.8-8.2), past history of limb damage (OR=1.7, 95% CI :0.9-3.1) and the number of excised lymph nodes (OR=1.06, 95% CI :1.02-1.09) were the significant predictors of lymphedema in women with BC. Modifiable risk factors of BCRL such as non-guided moderate to severe physical activity, high BMI and trauma to the limb should be controlled as early as possible in BC patients to prevent development of BCRL and improve QOL of these patients.

• Parasites, Hosts and Diseases
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• v.44 no.3
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• pp.177-185
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• 2006

Soil-transmitted helminths (STH), namely Ascaris, Trichuris and hookworms (Ancylostoma and Necator), present a global health problem to about a half of the earth's population. In the Republic of Korea, STH were highly prevalent and were considered a high priority target for national control. To promote the control, a non-governmental organization named Korea Association for Parasite Eradication (currently Korea Association of Health Promotion) was founded in 1964, and mass fecal examination followed by selective mass chemotherapy with anthelmintics was performed twice a year from 1969 to 1995 targeting whole nationwide schoolchildren. Meanwhile, decreasing patterns of national STH infections have been monitored by 7 times' quinquennial national surveys targeting general population. In 1971, the overall intestinal helminth egg positive rate was 84.3% (Ascaris 58.2%, Trichuris 65.4%, and hookworms 10.7%), which became 63.2% in 1976, 41.1% in 1981, 12.9% in 1986, 3.8% in 1992, 2.4% in 1997, and 4.3% (Ascaris 0.03%, Trichuris 0.02%, and hookworms 0%) in 2004. During the control period, national economy rapidly developed, and living standards including environment, sanitation, and agricultural technology greatly improved, which undoubtedly boosted the STH control effects. Our experience indicates that social driving force to establish an eligible national control system to conduct repeated mass chemotherapy, together with improvement of environment and sanitation, is important for initiating and achieving STH control in a developing community.

• Journal of the korean veterinary medical association
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• v.17 no.1
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• pp.51-54
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• 1981

The study was conducted to investigate the effects of Fenbendazol(FBZ) for the control of Cysticercus cellulosae in Jeju native swine. The results abtained were as follows: 1. The swine (S-l) has been 0.1g FBZ/kg body weight for 14 days and slaughtered in

• Progress in Medical Physics
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• v.4 no.1
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• pp.23-28
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• 1993

Radiation physics quality programs operate in a data rich enviranment. In quality control/quality assurance of treatment planning systems, quality indicators include isodose planning system, isodose calculation system, data set and equipment.

• The korean journal of orthodontics
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• v.24 no.1 s.44
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• pp.1-15
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• 1994

This study was attempted to explore the relationship between locus of control and the discomfort of the patients at the initial stage of the orthodontic treatment. Locus of control was measured by 'Locus of Control(LOC) scale for children' and 'Orthodontic Locus of Control(OLOC) scale for children'. The discomfort was measured by 'discomfort index card' in 52 children and adolescent patients who initiate orthodontic treatment. In addition, locus of control of the patients' mothers was measured by 'Orthodontic Locus of Control(OLU) scale for parents'. The results were as follows : 1. The test-retest reliability of 'Locus of Control(LOC) scale for children' and 'Orthodontic Locus of Control(OLOC) scale' was in the moderate to high range. 2. Out of 52 patients, 47 showed moderate to severe discomfort following placement of an initial archwire. The patients showed the most severe discomfort on the first day, and most of the discomfort was manifested within the first 3 days, then decreased until the 7th day. There was no significant difference in the discomfort according to sex and age. 3. The discomfort of the patients was the highest in the morning session when a day was divided into 4 sessions, i.e., morning, afternoon, evening, and night. 4. In the score of 'Locus of Control(LOC) scale for children' and 'Orthodontic Locus of Control(OLOC) scale for children', the group of internal locus of control expressed more discomfort than the group of external locus of control. And there was no significant correlation between locus of control of the patients and that of their mothers. 5. There was no significant difference in the score of locus of control according to sex and me. However, the score of boys tended to be lower than that of girls and the score of primary school students higher than that of middle and high school students.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7595-7600
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• 2013

Cervical cancer is a serious public health problem in developing countries. We investigated possible risk factors for cervical cancer in rural areas of Wuhan China using a matched case-control study with 33 women diagnosed with cervical cancer and 132 healthy women selected from the same area as matched controls. A questionnaire, which included questions about general demography conditions, environmental and genetic factors, the first sexual intercourse, first marriage age, age at first pregnancy, pregnancy first child's age, female personal health history, social psychological factors, dietary habits, smoking and alcohol status and other living habits was presented to all participants. At the same time, HPV infection of every participant was examined in laboratory testing. Results showed HPV infection (P<0.000, OR=23.4) and pregnancy first child's age (P<0.000, OR=13.1) to be risk factors for cervical cancer. Menopause (P=0.003, OR=0.073) was a protective factor against cervical cancer. However, there was no indication of associations of environmental (drinking water, insecticide, disinfectant) genetic (cancer family history), or life-style factors (smoking status, alcohol status, physical training, sleep quality), including dietary habits (intake of fruit and vegetable, meat, fried food, bean products and pickled food) or social psychological factors with cervical cancer. The results suggest that the risk of cervical cancer in Chinese rural women may be associated with HPV infection, menopause and the pregnancy first child's age.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.1
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• pp.58-61
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• 2002

The degree of doctors' autonomy is decided by the relations between the profession and the state. The exclusive right required by doctors is based on knowledge, but it is most often decided by the relations between the profession and the state. The critical factor affecting the status of the medical profession is the span of its control on medical related areas. Therefore, the status of doctors depends on the degree of institutionalization and the span of their control. The status of Korean Oriental Medicine doctors has been largely affected by the governments medical policies. The dramatic change of the status of Korean Oriental Medicine in modern Korea dearly shows the effects of medical policy on the status of a medical system. Under the plural medical system every medical group lobbies for more favorable medical policies. Korean Oriental Medicine doctors have secured an enhanced status in government and expanded the range of medical insurance coverage. Also, they have accomplished the standardization of knowledge in their efforts to expand it. These achievements are the most important aspects of the professionalization of Korean Oriental Medicine. Therefore, we can conclude that the conflicts between Korean Oriental Medicine doctors and government representatives have had significantly positive effects on the professionalization of Korean Oriental Medicine.

• The Korean Journal of Emergency Medical Services
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• v.20 no.1
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• pp.57-70
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• 2016

Purpose: This study aims to analyze the current state of emergency care for patients with anaphylaxis and to identify problems and areas for improvement in prehospital care. Methods: This study was conducted using 119 emergency running sheets and medical records of 109 patients diagnosed with anaphylaxis. Questionnaires were also given to emergency medical technicians (EMTs) and emergency physicians. The data were analyzed using SPSS 21.0. Results: Prehospital emergency care included oxygen administration in 64.2%, an intravenous line in 15.6%, and medication injection in 11.0%. The most commonly administered medications were antihistamines in 66.7% and epinephrine in 8.3%. Of EMTs surveyed, 47.0% suggested an epinephrine injection and using direct medical control, while 53.8% of the emergency physicians suggested an epinephrine injection and using indirect medical control. Most emergency physicians 88.8% responded that epinephrine could be administered by EMTs. Conclusion: The data support epinephrine injection of patients with anaphylaxis by EMTs, but a larger sample size of EMTs is required. Education about the treatment of anaphylaxis should be improved for EMTs. The scope of paramedic responsibilities should also be redefined.

• The Korean Journal of Physiology and Pharmacology
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• v.6 no.3
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• pp.161-163
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• 2002

Apoptosis has been hypothesized to be involved in the pathogenesis in schizophrenia. A large number of genes are known to mediate the apoptotic process; Apo-1/Fas (CD95) is a well-known example of such genes. In the present study, MvaI restriction fragment length polymorphism, a polymorphic marker present within the Apo-1/Fas gene, was examined in a population consisting of 226 control subjects and 110 schizophrenia patients, all of them Korean in ethnicity. No statistically significant difference in the genotypic distribution and allelic frequencies was observed between the control and the schizophrenia patient group. To find out the precise effect of Apo-1/Fas gene polymorphisms on the susceptibility to schizophrenia, further studies are warranted to investigate possible involvement of other polymorphisms with a larger sample population.

• Journal of Biomedical Engineering Research
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• v.44 no.2
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• pp.99-108
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• 2023

According to the COVID-19, development of various medical software based on IoT(Internet of Things) was accelerated. Especially, interest in a central software system that can remotely monitor and control ventilators is increasing to solve problems related to the continuous increase in severe COVID-19 patients. Since medical device software is closely related to human life, this study aims to develop central monitoring system that can remotely monitor and control multiple ventilators in compliance with medical device software development standards and to verify performance of system. In addition, to ensure the safety and reliability of this central monitoring system, this study also specifies risk management requirements that can identify hazardous situations and evaluate potential hazards and confirms the implementation of cybersecurity to protect against potential cyber threats, which can have serious consequences for patient safety. As a result, we obtained medical device software manufacturing certificates from MFDS(Ministry of Food and Drug Safety) through technical documents about performance verification, risk management and cybersecurity application.