• 한국방사선학회논문지
• /
• 제17권5호
• /
• pp.693-699
• /
• 2023

초음파는 의료분야에서 비파괴적 및 비침습적인 질병 진단에 널리 활용되고 있다. 진단의료영상의 질병진단 정확도를 향상시키기 위하여 공간 분해능을 향상시키는 것은 매우 중요하다. 본 연구에서는 초음파 영상에서의 초고분해능 합성곱 신경망 알고리즘 (super resolution convolutional neural network, SRCNN)을 모델링하여 적용 가능성을 분석하고자 한다. 연구는 Field II 시뮬레이션과 open source로 제공되는 임상 간 혈관종 초음파 영상을 사용한 실험 연구로 수행되었다. 제안하는 SRCNN 알고리즘은 저분해능 (low resolution, LR)에서 고분해능 (high resolution)으로 end-to-end 방식의 학습이 적용될 수 있도록 모델링하였다. 시뮬레이션 결과 Field II 프로그램을 통한 팬텀 영상에서의 반치폭 값은 SRCNN을 사용하였을 때 LR에 비하여 41.01% 향상되는 것을 확인하였다. 또한, 최대신호대잡음비 (peak to signal to noise ratio, PSNR)와 구조적 유사도 지표 (structural similarity index, SSIM)) 평가 결과는 시뮬레이션과 실제 간 혈관종 영상에서 SRCNN이 가장 우수한 값으로 도출되었다. 결론적으로 SRCNN의 초음파 영상에서의 적용 가능성을 증명하였고, 나아가 다양한 진단의료분야에서의 사용이 가능할 것으로 기대한다.

• 대한의용생체공학회:의공학회지
• /
• 제31권2호
• /
• pp.94-98
• /
• 2010

In magnetic resonance electrical impedance tomography (MREIT), a current-injection MR imaging method is adopted to produce a cross-sectional image of an electrical conductivity distribution in addition to MR images. The purpose of this study was to test the feasibility of MREIT for differentiating the canine lung parenchyma without and with pneumonia. Three normal healthy beagles and two mixed breed dogs with pneumonia were used. After attaching electrodes around the chest, we placed the dog inside our MR scanner. We injected as much as 30 mA current in a form of short pulses into the chest region. Reconstructed conductivity images of normal canine lungs exhibit a peculiar pattern of a relatively coarse salt and pepper noise. On the contrary, conductivity images of pneumonic canine lungs show significantly enhanced contrast of the lesions while the corresponding MR images show a little bit of contrast in the middle and caudal lung parenchyma due to the accumulation of pleural fluid. This preliminary study indicates that MREIT imaging of the chest may deliver unique new diagnostic information.

• 대한의용생체공학회:의공학회지
• /
• 제18권2호
• /
• pp.121-126
• /
• 1997

Endoscopy has become a crucial diagnostic and therapeutic procedure in clinical areas. Over the past three years, we have developed a computerized system to record and store clinical data pertaining to endoscopic surgery of laparascopic cholecystectomy, pelviscopic endometriosis, and surgical arthroscopy. In this study, we developed a computer system, which is composed of a frame yabber, a sound board, a VCR control board, a LAN card and EDMS(endoscopic data management software. Also, computer system has controled peripheral instruments such as a color video printer, a video cassette recorder, and endoscopic input/output signals(image and doctor's comment). Digital endoscopic data management system is based on open architecture and a set of widely available industry standards, namely: windows 3.1 as a operating system, TCP/IP as a network protocol and a time sequence based database that handles both images and doctor's cotnments. For the purpose of data storage, we used MOD and CD-R. Digital endoscopic system was designed to be able to store, recreate, change, and compress signals and medical images.

• 한국의학물리학회지:의학물리
• /
• 제24권1호
• /
• pp.76-83
• /
• 2013

진단 및 치료분야에서 호흡 움직임이 미치는 영향에 대한 연구는 외부 움직임을 관찰하여 실시되었으나, 이러한 외부 움직임은 내부 장기의 실제 움직임을 반영하지 못한다. 이에 본 연구에서는 개의 흉부 내 비침습적 이식이 가능한 인공 폐결절을 제작하여 동물실험에 대한 적용가능성을 확인하고 PET 영상 획득 및 방사선조사 시 움직임의 영향을 평가하고자하였다. 인공폐결절은 8 Fr 일회용 위장용 영양공급튜브를 개조하여 제작하였다. 제작된 결절모델은 마취된 개 4마리에 기관을 경유하여 기관지에 삽입한 뒤 방사선투시장치를 이용하여 위치를 확인하였다. PET 촬영용 인공폐결절은 내강에 $^{18}F$-FDG를 주입한 뒤 호흡운동 모사체에 장착하여 정지 상태, 10 rpm과 15 rpm의 종축 왕복운동간 PET 촬영을 실시하였다. 방사선조사용 인공폐결절은 유리선량계를 이식한 뒤 PET 촬영 시와 동일한 호흡운동 모사체에 장착하여 정지 상태, 10 rpm과 15 rpm의 종축 왕복운동간 1 Gy 선량을 조사하였다. 인공폐결절은 방사선투시장치 영상에서 실험동물의 후엽 근위부 세기관지에 이식되며 호흡에 따라 결절의 위치가 변화함을 확인하였다. PET 영상에서의 인공폐결절은 모사된 호흡 움직임에 따라 움직임에 의한 인공산물을 나타내었으며, 호흡동조게이트 시 SNR은 7.21로 기준영상의 SNR 10.15에 비해 감소하였으나 프로파일상 게이트영상의 영상계수는 정적영상에 비해 기준영상과 유사하여 PET 영상의 질을 개선함을 확인하였다. 방사선조사 실험간 인공폐결절 내 삽입된 유리선량계에 조사된 조사선량은 정지 상태와 10 rpm의 종축 왕복운동에서 0.91 Gy로 차이를 보이지 않았으나, 15 rpm의 종축 왕복운동에서 0.90 Gy로 오차범위 내 감소를 나타내었으며, 이온 전리함을 통한 조사선량 검출에서도 근소한 감소를 나타내었다. 본 실험에서 제작된 인공폐결절은 실험동물의 후엽 근위부 세기관지에 높은 재현성을 보이며 방사선투시 영상에서 폐의 내부 움직임을 반영하였다. PET 영상 내 움직임에 의한 인공산물이 관찰되며, 방사선 조사연구에서는 호흡운동이 미약한 영상 흐림을 일으킴을 확인하였다. 따라서 본 인공폐결절은 진단 및 치료분야에서 실험동물을 이용한 움직임 기반 진단 및 치료 평가에 유용한 도구로 사용될 것으로 기대된다.

• Journal of Magnetics
• /
• 제22권1호
• /
• pp.55-59
• /
• 2017

The purpose of this study was to quantitatively evaluate image quality using intensity profile, coefficient of variation (COV), and peak signal to noise ratio (PSNR) with respect to noise reduction techniques in the ultrasound images. For that purpose, we compared with the median filter, Rudin-Osher-Fatemi (ROF), Anscombe and proposed patch group prior based denoising (PGPD) techniques. To evaluate image quality, the Shepp-Logan phantom and the ultrasound image were acquired using simulation and experiment, respectively. According to the results, the difference of intensity profile using PGPD technique is lowest compared with original Shepp-Logan phantom. In simulation, the measured COV was 0.249, 0.198, 0.198, 0.177, and 0.080 using noisy, median, ROF, Anscombe and PGPD technique, respectively. Also, in experimental image, the measured COV was 0.245, 0.230, 0.231, 0.242 and 0.187 using noisy, median, ROF, Anscombe and PGPD technique, respectively. Especially, when we used PGPD technique, the PSNR has highest value in both simulation and experiment. In this study, we performed simulation and experiment study to compare various denoising techniques in the ultrasound image. We can expect the PGPD technique to improve in medical diagnosis with excellent noise reduction.

• 대한디지털의료영상학회논문지
• /
• 제7권1호
• /
• pp.33-38
• /
• 2005

Modern hospitals have been greatly facilitated with information technology (IT) such as hospital information system (HIS). One of the most prominent achievements is medical imaging and image data management so-called Picture Archiving and Communication Systems (PACS). Due to inevitable use of diagnostic images (such as X-ray, CT, MRI), PACS made tremendous impact not only on radiology department but also nearly all clinical departments for exchange and sharing image related clinical information. There is no doubt that better use of PACS leads to highly efficient clinical administration and hospital management. However, due to rapid and widespread acceptance of PACS storage and management of digitized image data in hospital introduces overhead and bottleneck when transferring images among clinical departments within and/or across hospitals. Despite numerous technical difficulties, financing for installing PACS is a major hindrance to overcome. In addition, a mirroring or a clustering backup can be used to maximize security and efficiency, which may not be considered as cost-effective approach because of extra hardware expenses. In this study therefore we have developed a new based on grid of distributed PACS in order to balance between the cost and network performance among multiple hospitals.

• 대한의용생체공학회:의공학회지
• /
• 제42권5호
• /
• pp.201-210
• /
• 2021

In Korean medicine, tongue diagnosis is one of the important diagnostic methods for diagnosing abnormalities in the body. Representative features that are used in the tongue diagnosis include color, shape, texture, cracks, and tooth marks. When diagnosing a patient through these features, the diagnosis criteria may be different for each oriental medical doctor, and even the same person may have different diagnosis results depending on time and work environment. In order to overcome this problem, recent studies to automate and standardize tongue diagnosis using machine learning are continuing and the basic process of such a machine learning-based tongue diagnosis system is tongue segmentation. In this paper, image data is augmented based on the main tongue features, and backbones of various famous deep learning architecture models are used for automatic tongue segmentation. The experimental results show that the proposed augmentation technique improves the accuracy of tongue segmentation, and that automatic tongue segmentation can be performed with a high accuracy of 99.12%.

• Journal of Korean Neurosurgical Society
• /
• 제53권1호
• /
• pp.39-42
• /
• 2013

Objective : Obtaining real-time image is essential for neurosurgeons to minimize invasion of normal brain tissue and to prompt diagnosis of intracranial event. The aim of this study was to report our three-year experience with a mobile computed tomography (mCT) for intraoperative and bedside scanning. Methods : A total of 357 mCT (297 patients) scans from January 2009 to December 2011 in single institution were reviewed. After excluding postoperative routine follow-up, 202 mCT were included for analysis. Their medical records such as diagnosis, clinical application, impact on decision making, times, image quality and radiologic findings were assessed. Results : Two-hundred-two mCT scans were performed in the operation room (n=192, 95%) or intensive care unit (ICU) (n=10, 5%). Regarding intraoperative images, extent of resection of tumor (n=55, 27.2%), degree of hematoma removal (n=42, 20.8%), confirmation of catheter placement (n=91, 45.0%) and monitoring unexpected complications (n=4, 2.0%) were evaluated. A total of 14 additional procedures were introduced after confirmation of residual tumor (n=7, 50%), hematoma (n=2, 14.3%), malpositioned catheter (n=3, 21.4%) and newly developed intracranial events (n=2, 14.3%). Every image was obtained within 15 minutes and image quality was sufficient for interpretation. Conclusion : mCT is feasible for prompt intraoperative and ICU monitoring with enhanced diagnostic certainty, safety and efficiency.

• 대한디지털의료영상학회논문지
• /
• 제14권2호
• /
• pp.39-46
• /
• 2012

Purpose : The purpose of this study was to reduce Entrance Surface Dose and maintain image quality by changing Source to Image receptor Distance. And we'd like to compare ESD on this study to DRLs in other contries. Materials and Methods : We used indirect DR system(Definium 8000, General Electric, USA)and phantom(ART-200X, Flukebiomedical, USA),glass dosimeters(GD-352M, Asahi Techno Glass, Japan)for this study. The imagies were obtained throuh 80kVp fixed, and different tube currents using AEC mode in $16{\times}16$(inch) field size and changing Source to Image receptor Distance from 100 cm to 130 cm per 10 cm unit. The phantom with attaching 5 glass dosimeters on abdomonal skin was set at supine and erect position as a anterioposterial projection on detector For measuring Entrance Surface Dose. Image analysis was conducted by histograms of Image J(1.46r) which was given from National Institutes of Health(NIH). Results : Due to inverse square law of distance, the tube currents were increasing 42.6 % in supine position and 32.6 % in erect position according to the change of Source to Image receptor Distance. While Entrance Surface Doses were rapidly decreasing 14.2 % in supine position and 29.4 % in erect position according to the change of Source to Image receptor Distance. As the results of histogram using Image J, pixel mean values from 100 cm to 110 cm, 120 cm and 130 cm were decreasing each 1.4%, 2.5%, 2.7%, 4.5%, 2.2 %, 5.8 % in supine, erect position. While standard deviations from 100 cm to 110 cm, 120 cm and 130 cm were increasing each 1.4 %, 2.5 %, 2.5 %, 4.0 %, 2.0 %, 4.9 % Consequently, there are no significant differences in abdomen images taken. Conclusion: As the results described above, we strongly recommend using long Sourceto Image receptor Distance than 100cm that we have been using. So, we should deliver less Entrance Surface Dose to the patients while maintaining image quality in abdomen radiography.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권15호
• /
• pp.6177-6186
• /
• 2015

Sensitivity and specificity are the two most important indicators in selection of medical imaging devices for cancer screening. Breast images taken by conventional or digital mammography, ultrasound, MRI and optical mammography were collected from 2,143,852 patients. They were then studied and compared for sensitivity and specificity results. Optical mammography had the highest sensitivity (p<0.001 and p<0.006) except with MRI. Digital mammography had the highest specificity for breast cancer imaging. A comparison of specificity between digital mammography and optical mammography was significant (p<0.021). If two or more breast diagnostic imaging tests are requested the overall sensitivity and specificity will increase. In this literature review study patients at high-risk of breast cancer were studied beside normal or sensitive women. The image modality performance of each breast test was compared for each.