• 대한한의학회지
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• 제23권2호
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• pp.1-18
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• 2002

Objectives : The objective of this study was to examine the academic informationseeking behavior and demand of the oriental medical researcher and to create the base data for establishing a library environment providing a high-quality information service which would aid the activity of such researchers, Methods : We distributed a questionnaire to the one hundred professors of the college of oriental medicine on the method of acquisition of information data, the environment of the library belonging to the college, and the like. Results : $\circled1$ The main class using the academic information service of oriental medicine was revealed to be researchers having a career of 10 to 15 years who had a domestic doctorate in oriental medicine. $\circled2$ When accessing information, the primary information resource used was academic journals. $\circled3$ Of the data forms mentioned in the study, periodicals was used most in number of printed data; computer databases among non-printed data. $\circled4$ The purpose of using an information resource was for performing a research project. $\circled5$ The path of acquisition of information was usually through the materials in their possession. $\circled6$ The greatest difficulty in gathering information was first of all the lack of information owned by the library, and next a lack of time and insufficient knowledge of information search and use. $\circled7$ More than 90% of respondents on the necessity of an expert library answered as "necessary" or "certainly necessary", indicating that the foundation of an expert library is very urgent. Conclusions : This study is beneficial for researchers engaged in oriental medicine to activate the use of information and also it will form a base of data for researchers to establish an environment of expert library in oriental medicine.

• 한국임상약학회지
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• 제25권4호
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• pp.254-263
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• 2015

Objectives: The present study assessed the prevalence of the potentially inappropriate medication (PIM) use in Korean elderly patients with Parkinson's disease. In addition, this study examined risk factors that affect PIM use. Method: A retrospective, observational study was conducted using Korean National Health Insurance claims database of 2009. PIM use in Parkinson's disease patients aged 65 years or older was examined based on 2012 Beers Criteria. Multivariable logistic regression was conducted to identify risk factors for PIM use. Results: Among 5,277 elderly patients with Parkinson's disease, 88.9% of patients used PIM(s) at least once. The average number of PIM items used per patient was 4.2. PIM use ratio, the proportion of total amount of PIMs to all medications per patient, was 12.6%. Frequently used PIM therapeutic classes were benzodiazepines (32.7%), first-generation antihistamines (19.2%), and prokinetics (17.5%). Individual PIMs most commonly used included chlorpheniramine (11.4%), levosulpiride (10.9%), diazepam (9.0%), and alprazolam (7.6%). Women (odds ratio [OR] 1.14, 95% confidence interval [CI] 1.11-1.16), medical aid (OR 1.18, 95% CI 1.15-1.21), and long-term facilities (OR 2.43, 95% CI 2.22-2.65) were shown to be risk factors associated with PIM use. Of particular, wide variation in PIM use was associated with the types of healthcare facility. Conclusion: The PIM prevalence was very high in elderly Parkinson's disease patients. Nationally effective and systematic efforts to identify and prevent PIM use should be made to ensure patient safety and to improve quality of care in the elderly.

• 약학회지
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• 제57권3호
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• pp.199-204
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• 2013

This study aimed to quantify antibiotic consumption and expenditures for acute upper respiratory tract infections (URIs) (J00-J06) in outpatients from 2009 to 2011. We used WHO ATC classification and DDDs in measuring antibiotic consumption. National Health Insurance and Medical Aid claims data were analyzed. Antibiotic consumption has decreased from 4.44 DDD/1,000inhabitants/day in 2009, to 4.43 in 2010 and 3.74 in 2011. The estimated expenditures were 8,206 won/1,000inhabitants/day in 2009, 8,379 in 2010, and 7,004 in 2011. Clinics accounted for 89.8% and 86.0% of antibiotic consumption and expenditures respectively for the acute URIs in 2011. We need to monitor antibiotic consumption consistently, and promote judicious antibiotic use.

• IMMUNE NETWORK
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• 제14권2호
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• pp.73-80
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• 2014

Because autoimmune diseases (AIDs) result from a complex combination of genetic and epigenetic factors, as well as an altered immune response to endogenous or exogenous antigens, systems biology approaches have been widely applied. The use of multi-omics approaches, including blood transcriptomics, genomics, epigenetics, proteomics, and metabolomics, not only allow for the discovery of a number of biomarkers but also will provide new directions for further translational AIDs applications. Systems biology approaches rely on high-throughput techniques with data analysis platforms that leverage the assessment of genes, proteins, metabolites, and network analysis of complex biologic or pathways implicated in specific AID conditions. To facilitate the discovery of validated and qualified biomarkers, better-coordinated multi-omics approaches and standardized translational research, in combination with the skills of biologists, clinicians, engineers, and bioinformaticians, are required.

• Archives of Plastic Surgery
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• 제41권3호
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• pp.213-217
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• 2014

The widespread use of microsurgery in numerous surgical fields has increased the need for basic microsurgical training outside of the operating room. The traditional start of microsurgical training has been in undertaking a 5-day basic microsurgery course. In an era characterised by financial constraints in academic and healthcare institutions as well as increasing emphasis on patient safety, there has been a shift in microsurgery training to simulation environments. This paper reviews the stepwise framework of microsurgical skill acquisition providing a cost analysis of basic microsurgery courses in order to aid planning and dissemination of microsurgical training worldwide.

• 한국임상수의학회지
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• 제26권2호
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• pp.166-169
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• 2009

11년령의 수컷 비글(10.5 kg)이 사고로 과량의 딜티아젬을 섭취한 후 급작스러운 서맥과 심한 저혈압으로 내원하였다. 환자는 경피용 체외 심박조절기의 적용하에서 등장성 crystalloid 용액, 아트로핀, calcium gluconate, 도부타민, 글루카곤, 위세척의 처치를 받았다. 단기간의 경피용 체외심박조절기의 사용과 약물적 치료요법으로 환자의 심장 리듬과 상태는 안정화 되었다.

• 대한약침학회지
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• 제23권3호
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• pp.142-157
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• 2020

Cannabis is a historical plant which has been used as a medicine in East Asia. These days, there are active debates about using cannabis in clinical field. Collecting and comparing cannabis research articles which had been published in the Opening of Japan to spot the interactions between the traditional medicine of Japan, Rangaku which was established in Edo Period and the European medicine which is transferred after Perry Expedition is academically meaningful. This study searched publications, which were listed on Open-Access databases by Dec. 11^th, 2019. We collected research articles which had been published from January 3^rd, 1867 to July 30^th, 1912 also known as Meiji era and uploaded on OpenAccess databases. Our searching databases were J-stage, CiNii (Scholarly and Academic Information Navigator), Tokyo Metropolitan Library, The National Diet Library, IRDB (Institutional Repositories DataBase) and KAKEN (Grant-in-Aid for Scientific Research Database). Searching keywords were cannabis, hemp and all their Japanese synonyms and available combinations. We selected final 15 studies which met every selection criteria in the 346,393 collected studies. Cannabis was prescribed in Meiji era of Japan to alleviate pain and cure the digestive, respiratory, urinary, and nervous system diseases such as indigestion, asthma, tuberculosis, gonorrhea and its complications, insomnia, and nervous prostration. Cannabis was medically used in Meiji era of Japan and the reporting and sharing of its clinical effect was published on the medical journals like present days. There were already Cannabis regulations in that era, but its medicinal use was more liberated than nowadays. It may be a chance to reconsider the current legal system, which strictly controls the use of Cannabis.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• 제26권1호
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• pp.30-36
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• 2024

Objective: This study aims to investigate the efficacy of microsurgery with intraoperative indocyanine green (ICG) angiography as a treatment approach for ethmoidal dural arteriovenous fistula (DAVF). Methods: Between January 2010 and July 2021, our institution encountered a total of eight cases of ethmoidal DAVF. In each of these cases, microsurgical treatment was undertaken utilizing a bilateral sub-frontal interhemispheric approach, with the aid of intraoperative ICG angiography. Results: ICG angiography identified bilateral venous drainage with single dominance in four cases (50%) of ethmoidal DAVF, a finding that eluded detection during preoperative transfemoral cerebral angiography (TFCA). The application of microsurgical treatment, in conjunction with intraoperative ICG angiography, resulted in consistently positive clinical outcomes for all patients, as evaluated using the Glasgow Outcome Scale (GOS) at the 6-month postoperative follow-up assessment; six patients showed GOS score of 5, while the remaining two patients attained a GOS score of 4. Conclusions: The use of intraoperative ICG angiography enabled accurate identification of both dominant and non-dominant venous drainage patterns, ensuring complete disconnection of the fistula and reducing the risk of recurrence.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제25권4호
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• pp.295-303
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• 1999

Presented in this paper are the experimental results that measure rapid prototyping (RP) errors in 3D medical models. We identified various factors that can cause dimensional errors when producing RP models, specifically in maxillofacial areas. For the experiment, we used a human dry skull. A number of linear measurements based on landmarks were first obtained on the skull. This was followed by CT scanning, 3D model reconstruction, and RP model fabrication. The landmarks were measured again on both the reconstructed models and the physical RP models, and these were compared with those on dry skull. We focused on major sources of errors, such as CT scanning, conversion from CT data to STL models, and RP model fabrication. The results show that the overall error from skull to RP is $0.64{\times}0.36mm(0.71{\times}0.66%)$ in absolute value. This indicates that the RP technology can be acceptable in the real clinical applications. A clinical case that has applied RP models successfully for treatment planning and surgical rehearsal is presented. Although the use of RP models is rare in the medical area yet, we believe RP is promising in that it has a great potential in developing new tools which can aid diagnosis, treatment planning, surgical rehearsal, education, and so on.

• 한국산학기술학회논문지
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• 제14권2호
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• pp.707-712
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• 2013

급성심근경색환자에서 증상발병후 병원도착지연이 질병과 사망률에 중요한 관련이 있다. 이 연구에서는 환자의 증상 인식 등 응급의료체계 활성화 이전 단계의 의료기관 내원 지연의 원인을 연구하여, 향후 내원지연 시간 감소를 위해 적절한 보건교육 및 치료의 방향을 찾고자 하였다. 연구 샘플은 2009년 6월에서 9월까지 급성심근경색으로 입원한 환자를 대상으로 하였다. 인구통계, 의료기록 및 임상자료는 병원진료기록를 이용하였으며, 병원전 지연은 6시간이전과 이후로 분류하였다. 급성심근경색증 환자들에서 내원시간 지연에 영향을 미치는 요인으로는 고령인 경우, 낮은 사회경제적 위치, 응급의료체계의 이용하지 않고 내원 한 경우와 급성심근경색을 위한 응급처치의 지연등이다. 따라서 사회경제적 위치가 낮은 계층과 고령층에 대한 급성관상동맥 증후군의 증상에 대한 지식을 높이고 증상발생시 의료기관을 빠르게 이용하도록 교육이 필요하다.