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Transcutaneous Cardiac Pacing in a Dog with Diltiazem Intoxication  

Lee, Seung-Keun (Korea Animal Hospital)
Hyun, Chang-Baig (Section of Small Animal Internal Medicine, School of Veterinary Medicine, Kangwon National University)
Publication Information
Journal of Veterinary Clinics / v.26, no.2, 2009 , pp. 166-169 More about this Journal
Abstract
An 11-year-old male Beagle, weighing 10.5 kg, was presented with sudden bradyarrhthmia and severe hypotension after incidental ingestion of diltiazem. The dog was treated with intravenous(IV) isotonic crystalloid solution, atropine, calcium gluconate, dobutamine, glucagon and gastric lavage under the aid of temporary transcutaneous cardiac pacing. With the short-term use of transcutaneous cardiac pacing and medical treatment, the heart rhythm and the condition of the patient were stabilized.
Keywords
Diltiazem intoxication; calcium channel blocker; cardiac pacing; temporary pacing;
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1 Niemann JT, Rosborough JP, Garner D. External noninvasive cardiac pacing: a comparative hemodynamic study of two techniques with conventional endocardial pacing. Pacing Clin Electrophysiol 1984; 7: 230-236   DOI   ScienceOn
2 Ramoska EA, Spiller HA, Winter M, Borys D. A one-year evaluation of calcium channel blocker overdoses: toxicity and treatment. Ann Emerg Med 1993; 22: 196–200   DOI   ScienceOn
3 Romano G, Barbera N, Rossitto C, Spadaro G. Lethal diltiazem poisoning. J Anal Toxicol 2002; 26: 374–377   DOI   PUBMED   ScienceOn
4 Kittleson MD, Kienle RD. Drug used in treatment of cardiac arrhythmia. In: Small Animal Cardiovascular Medicine. St. Louis: Mosby, 1998: 502-524
5 TC, Hansen BD, Atkins CE, Sidley JA, Keene BW. Noninvasive transthoracic temporary cardiac pacing in dogs. J Vet Intern Med 2003; 17: 663-667   DOI   PUBMED   ScienceOn
6 Zoll PM, Belgard AH, Weintraub MJ, Frank HA. External mechanical cardiac stimulation. N Engl J Med 1976; 294: 1274-1275   DOI   PUBMED   ScienceOn
7 Plumb DC. Plumb's Veterinary Drug Handbook, London: Blackwell Publishers, 2005; 369-371
8 Gelzer AR, Kraus MS. Management of atrial fibrillation. Vet Clin North Am Small Anim Pract 2004; 34: 1127–1144   DOI   ScienceOn
9 Isbister GK. Delayed asystolic cardiac arrest after diltiazem overdose; resuscitation with high dose intravenous calcium. Emerg Med J 2002; 19: 355–357   DOI   ScienceOn
10 Holder T. Calcium channel blocker toxicosis. Vet Med 2000; 95: 912–915
11 Roberts D, Honcharik N, Sitar DS, Tenenbein M. Diltiazem overdose: pharmacokinetics of diltiazem and its metabolites and effect of multiple dose charcoal therapy. J Toxicol Clin Toxicol 1991; 29: 45–52   DOI   PUBMED   ScienceOn
12 Schoffstall JM, Spivey WH, Gambone LM, Shaw RP, Sit SP. Effects of calcium channel blocker overdose-induced toxicity in the conscious dog. Ann Emerg Med 1991; 20: 1104–1108   DOI   ScienceOn
13 Hussain MD, Tam YK, Finegan BA, Coutts RT. Simple and sensitive high-performance liquid chromatographic method for the determination of diltiazem and six of its metabolites in human plasma. J Chromatogr 1992; 582: 203–209   DOI   PUBMED   ScienceOn
14 Proano L, Chiang WK, Wang RY. Calcium channel blocker overdose. Am J Emerg Med 1995; 13: 444–450   DOI   ScienceOn
15 Syring RS, Costello MF, Poppenga RH. Calcium channel blocker toxicity. J Vet Emerg Crit Care. 2008; 18: 75-80   DOI   ScienceOn
16 Lee S, Hyun C. Evaluation of changes in cardiac biomarkers and serum enzymes after short (1 hr) and long-duration (3 hr) transcutaneous cardiac pacing. Am J Vet Res 2008; in press
17 Syverud SA, Dalsey WC, Hedges JR. Transcutaneous cardiac pacing: determination of myocardial injury in a canine model. Ann Emerg Med 1983; 12: 745–748   DOI   ScienceOn
18 Cooke KL, Snyder PS. Calcium channel blockers in veterinary medicine. J Vet Intern Med 1998; 12: 123–131   DOI   ScienceOn