• 한국산업보건학회지
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• 제23권1호
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• pp.20-26
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• 2013

Objectives: This study was conducted to evaluate the health risk of workers exposed to butyl glycidyl ether to prevent them from developing occupational diseases. Methods: The workplaces that coat floor with epoxy were selected and the samples were collected and analyzed with NIOSH 1616 Method. We calculate workplace reference concentration using with NOAEL estimated by the study of Anderson et al. in 1978. Risk was calculated by the ratio of exposure to workplace reference concentration. Monte-Carlo simulation was performed to derivate the median, cumulative 90%, and cumulative 95% value by using Crystal Ball. Results: Butyl glycidyl ether is a skin, eye irritator and can result in central nervous system depression, allergic reaction. NOAEL was 38 ppm and workplace reference concentration was calculated as 0.73 ppm corrected with uncertainty factors. Geometric mean was 1.152 ppm and geometric standard deviation was 1.522 by the workplace environment measurement. The median, cumulative 90%, and cumulative 95% value of risk were calculated as 1.617, 1.934, and 2.092, respectively. Conclusions: Not only cumulative 90% and cumulative 95% value but also the median of risk is higher than 1.0 by the risk characterization, so it can do a lot of harm to workers. Therefore, the process of derivating workplace reference concentration and the appropriacy of the uncertainty factors should be re-examined.

• 산업경영시스템학회지
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• 제15권25호
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• pp.11-14
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• 1992

This paper presents a method for establishing an initial value of redundancy optimization problem to maximize system reliability of multiconstraint mixed parallel-series system. The constraints not be linear. This paper proposes a new initial value which is near to optimal solution by considering the relative median rate of the unreliability and amount of consumed resources for each subsystem. To show the efficiency of this model. numerical example and comparison with Narasimhalu is illustrated in chapter 4.

• Journal of Korean Neurosurgical Society
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• 제54권3호
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• pp.232-235
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• 2013

Objective : Major complaints of carpal tunnel syndrome (CTS) are sensory components. However, motor deficit also impedes functional status of hand. Contrary to evaluation of sensory function, the objective, quantitative evaluation of median nerve motor function is not easy. The motor function of median was evaluated quantitatively using load cell and its correlation with findings of electrodiagnostic study (EDS) was evaluated. Methods : Objective motor function of median nerve was evaluated by load cell and personal computer-based measurement system. All of the measurement was done in patients diagnosed as having idiopathic CTS by clinical features and EDS findings. The strength of thumb abduction and index finger flexion was measured in each hand three times, and the average value was used to calculate thumb index ratio (TIR). The correlation of TIR with clinical, EDS, and ultrasonographic findings were evaluated. Results : The TIR was evaluated in 67 patients (119 hands). There were 14 males and 53 females, mean age were 57.6 years (range 28 to 81). The higher preoperative nerve conductive studies grade of the patients, the lower TIR was observed [p<0.001, analysis of variance (ANOVA)]. TIR of cases with thenar atrophy were significantly lower than those without (p<0.001, t-test). TIR were significantly lower in patients with severe median nerve swelling in ultrasonography (p=0.042, ANOVA). Conclusion : Measurements of median nerve motor function using load cell is a valuable evaluation tool in CTS. It might be helpful in detecting subclinical motor dysfunction before muscle atrophy develops.

• 보건행정학회지
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• 제33권2호
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• pp.203-213
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• 2023

This study examined the trend of healthcare status and compared the status of South Korea and other member of the Organization for Economic Cooperation and Development (OECD) using the OECD health statistics 2022. We used the OECD health statistics from 2022 and a position value for relative comparison (PARC) index to compare the five elements of the healthcare system. The study also used a Mann-Kendall test to analyze the trend of the PARC values from 2000 to the present year. The findings of the study indicate that many South Korea's PARC values were higher than the OECD median. But practicing physician in supply part and medical cost were lower than OECD median but the trend significantly increased. Medical accessibility part and quality of care part except primary care, and mental health had a high relative position but the trend did not increased significantly. After outbreak of coronavirus disease 2019, there were changes in medical accessibility. Health screening and vaccinations showed an overall decline in 2020 compared to 2019. These results suggest that policymakers need to take necessary steps for a sustainable healthcare system in the country.

• 한국지하수토양환경학회지:지하수토양환경
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• 제18권3호
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• pp.82-92
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• 2013

This study has investigated naturally occurring radioactive materials (N.O.R.M; $^{238}U$, $^{222}Rn$) for 353 drinking groundwater wells in metamorphic rock areas in Korea. Uranium concentrations ranged from N.D (not detected) to 563.56 ${\mu}g/L$ (median value, 0.68 ${\mu}g/L$) and radon concentrations ranged from 108 to 11,612 pCi/L (median value, 1,400 pCi/L). Uranium and radon concentrations in the groundwater generally are similar to USA with similar geological setting. Uranium concentrations in 9 wells (2.6%) exceeded 30 ${\mu}g/L$, which is the maximum contaminant level (MCL) by the US environmental protection agency (EPA), radon concentrations in 46 wells (13%) exceeded 4,000 pCi/L, which is the Alternative MCL (AMCL) by the US.EPA. The log-log correlation coefficient between uranium and radon was 0.32. The correlation coefficient between uranium and pH was 0.12 and the correlation coefficient between radon and temperature was -0.01. The correlation coefficient between uranium and $HCO_3$ was 0.09 and the correlation coefficient between uranium and Ca was 0.11. The median value of uranium was high Chung-Buk (1.78 ${\mu}g/L$), Gyeong-Buk (1.37 ${\mu}g/L$), In-Cheon (1.06 ${\mu}g/L$) for each province. On the other hand, the median value of radon was high In-Cheon (2,962 pCi/L), Chung-Buk (2,339 pCi/L), Jeon-Buk (2,165 pCi/L) for each province. Jeon-Buk for log-log correlation coefficient is the highest (0.63) among provinces.

• 한국산학기술학회논문지
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• 제19권3호
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• pp.141-146
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• 2018

최근에 위치 인식 기술이 많은 관심을 받고 있다. 특히 실내에서 주변 환경에 영향을 받지 않고 사람이나 사물의 위치를 파악하고, 유용한 서비스를 제공하는 기술이 대두되고 있다. 기존에 물체나 사람의 위치를 인식하는 방법으로 보편적으로 GPS기술을 많이 사용하였다. GPS는 매우 효율적으로 위치를 감지하지만 실내에서의 위치를 파악하기는 어렵기 때문에 실내에서 위치 인식을 위한 방법으로 RFID의 사용이 대두되었다. RFID는 무선주파수를 이용하여 태그가 부착된 사물 또는 사람의 위치정보를 파악하는 기술이다. 본 논문에서는 RFID 시스템을 구성하고 태그를 이용하여 위치를 측정했다. 이때 실제위치와 측정된 위치간의 오차가 발생한다. 본 논문에서는 오차를 줄이기 위해 측정된 위치 데이터와 실제 위치 데이터를 이용하여 신경망을 훈련하였다. 이때 측정된 태그의 개수가 일정하지 않아 신경망을 훈련시키기 위한 입력값으로 적합하지 않으므로 무게중심 입력과 중앙값 입력으로 변환하여 입력하여 신경망을 훈련시켰다. 그 결과 신경망에 의한 위치 오차가 줄어든 것을 확인하였다. 또한 훈련시킨 개수를 50, 100, 200, 300개로 실험하여 데이터입력 개수와 오차의 상관관계를 확인하고, 신경망을 이용하여 훈련시켰을 때 무게중심 입력과 중앙값 입력을 사용했을 때의 오차를 비교하였다. 그 결과 훈련시킨 데이터 개수가 많을수록 오차가 줄어들고, 무게중심 입력보다 중앙값 입력을 사용했을 때 오차가 줄어드는 것을 확인하였다.

• 한국임상약학회지
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• 제25권3호
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• pp.151-158
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• 2015

Objective: This study was designed to compare pegfilgrastim and filgrastim in diffuse large B-cell lymphoma (DLBCL) patients treated with a rituximab with cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisone (R-CHOP) regimen in terms of clinical efficacy and cost-effectiveness. Method: Clinical efficacy was measured by trough level of absolute neutrophil count (ANC), days of ANC under 50% of baseline value, days of ANC under 90% of baseline value, duration of ANC recovery to baseline value, days of ANC less than $0.5{\times}10^9cells/L$, and difference of peak and trough level of ANC during 1 cycle of R-CHOP regimen. To evaluate cost-effectiveness, total prices of used filgrastim and pegfilgrastim within 1 cycle of R-CHOP were analyzed. Results: In terms of clinical efficacy, trough level of ANC and days to ANC recovery showed statistical significance. The median trough levels of ANC with administration of filgrastim and pegfilgrastim were 0.18 and 1.94 (p = 0.021), respectively, and the median durations of ANC recovery to baseline value were 5.5 days and 2 days (p = 0.023), respectively. For the median days of ANC under 50% of baseline value, days of ANC under 90% of baseline value, days of ANC less than $0.5{\times}10^9cells/L$, and difference of peak and trough level of ANC during 1 cycle of R-CHOP, the pegfilgrastim group performed better than the filgrastim group. However the difference was not statistically significant. In terms of overall expense during 1 cycle of R-CHOP, pegfilgrastim is about 3.43 times more expensive than filgrastim. Conclusion: Pegfilgrastim is more efficient than filgrastim in terms of clinical efficacy. In terms of prices, pegfilgrastim is more expensive than filgrastim for patients, but it is more convenient in clinical use. Therefore, pegfilgrastim should be the preferred choice of G-CSF for neutropenic patients. Further comparative study of pegfilgrastim and filgrastim is needed.

• 한국의학물리학회지:의학물리
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• 제26권4호
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• pp.229-233
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• 2015

정위 방사선치료를 받은 폐암환자에서 결과를 후향적으로 분석하고자 하였다. 연속된 흉부 컴퓨터단층촬영(CT)의 종양의 크기변화 분석을 통해 치료 반응 평가를 조사하였다. 11명의 초기 비소세포폐암환자를 대상으로 정위 방사선치료 선량의 중앙값은 6,000 cGy이고 분할 조사 회수의 중앙값은 5회였다. 경과 관찰기간의 중앙값은 28개월로 치료후 종양의 크기 변화는 총 51회의 CT를 통해 분석하였고, 각 환자당 중앙값 3회의 CT 촬영이 시행되었다. 본 연구에서 치료의 총 반응률은 90.9%로 5명의 환자에서 완전관해와 5명에서 부분관해가 관찰되었다. 부분관해와 완전관해까지의 기간의 중앙 값은 각각 3개월과 5개월이었다. 경과관찰에서 3명의 환자가 병의 진행양상을 나타내었다. 본 연구에서 초기 폐암의 정위방사선치료후 CT 분석을 통해 반응 평가와 함께 치료 반응 시점을 확인할 수 있었다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2005년도 추계종합학술대회
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• pp.981-984
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• 2005

현재, 영상처리에 있어서 잡음을 제거함과 동시에 영상의 에지성분을 보존하는 필터링 방법에 대한 연구가 활발히 진행되고 있다. 그리고 임펄스 노이즈 환경에서는 SM(standard median) 필터가우수한 잡음 제거 성능을 나타내었으나, 영상의 에지성분에 대한 오류가 발생하고 있다. 이에 따라, SM 필터를 개선한 다양한 방법들이 제안되었으며, CWM(center weighted median) 필터가 대표적이다. 또한, 에지의 보존이나 처리속도의 관점에서 더욱 향상된 성능을 나타내기 위한 방법으로 min-max 연산에 기반한 방법들이 있다 본 논문에서는 임펄스 노이즈에 의해 훼손된 화소에 대해, 그 화소를 둘러 싼 surrounding band의 최대 또는 최소 값을 이용하여 처리하였으며, 시뮬레이션을 통해 제안한 필터의 성능을 기존의 방법과 비교하였다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2014년도 추계학술대회
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• pp.798-801
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• 2014

현재, 디지털 시대의 급속 발전과 함께 멀티미디어 서비스에 대한 수요가 증가되고 있다. 그러나 영상 데이터를 처리, 전송, 저장하는 과정에서 여러 외부 원인에 의해 영상의 열화가 발생되며, 영상 열화의 주된 원인은 잡음에 의한 것으로 알려져 있다. 잡음을 제거하는 대표적인 방법은 CWMF(center weighted median filter), A-TMF(alpha-trimmed mean filter), AWMF(adaptive weighted median filter) 등이 있으며, 이러한 방법들은 복합잡음 환경에서의 잡음제거 특성이 다소 미흡하다. 따라서 본 논문에서는 복합잡음을 제거하기 위하여 잡음 판단을 거친 후, 마스크의 메디안 값 및 거리에 의해 적응 가중치를 설정하여 처리하는 영상복원 필터 알고리즘을 제안하였다. 그리고 객관적 판단을 위해 기존의 방법들과 비교하였으며, 판단의 기준으로 PSNR(peak signal to noise ratio)을 사용하였다.