• Archives of Plastic Surgery
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• v.43 no.3
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• pp.242-247
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• 2016

Background Median cleft lip is a rare anomaly consisting of a midline vertical cleft through the upper lip. It can also involve the premaxillary bone, the nasal septum, and the central nervous system. In our current report, we present the clinical features of 6 patients with a median cleft lip and their surgical management according to the accompanying anomalies. Methods From December 2010 to January 2014, 6 patients with a median cleft lip were reviewed. Five of these cases underwent surgical correction; alveolar bone grafting was performed in a patient with a median alveolar cleft. The surgical technique included inverted-U excision of the upper lip and repair of the orbicularis oris muscle. The mean follow-up period was 20.4 months (range, 7.4-44.0 months). Results The study patients presented various anomalous features. Five patients received surgical correction, 4 with repair of the median cleft lip, and one with iliac bone grafting for median alveolar cleft. A patient with basal sphenoethmoidal meningocele was managed with transoral endoscopic surgery for repair of the meningocele. Successful surgical repair was achieved in all cases with no postoperative complications. Conclusions Relatively mild forms of median cleft lip can be corrected with inverted-U excision with good aesthetic outcomes. In addition, there is a broad spectrum of clinical features and various anomalies, such as nasal deformity, alveolar cleft, and short upper frenulum, which require close evaluation. The timing of the operation should be decided considering the presence of other anomalies that can threaten patient survival.

• Clinical and Experimental Pediatrics
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• v.62 no.9
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• pp.353-359
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• 2019

Background: Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic cutoff values of EPO for use as a one-time test for allergic diseases such as allergic rhinitis have not been established. Purpose: To identify the correlation between nasal eosinophil count and EPO in children and adolescents with rhinitis. Methods: We recruited patients <18 years of age with rhinitis for more than 2 weeks or more than 2 episodes a year whose nasal eosinophil and EPO were measured at a single allergy clinic. The eosinophil percentage was calculated by dividing the eosinophil count by the number of total cells under light microscopy at ${\times}1,000$ magnification. EPO and protein were measured from nasal secretions. We retrospectively analyzed the correlation between nasal eosinophils and protein-corrected EPO (EPO/protein) value. Results: Of the 67 patients enrolled, 41 were male (61.2%); the mean age was $8.2{\pm}4.0years$. The median nasal eosinophil count was 1 and percentage was 1%. The median protein-corrected EPO value was $12.5ng/{\mu}g$ (range, $0-31ng/{\mu}g$). There was a statistically significant correlation between eosinophil count and percentage (P<0.001). However, the eosinophil percentage and EPO did not correlate. The eosinophil count and EPO had a statistically significant correlation (P=0.01). The EPO cutoff value examined for nasal eosinophil counts of 2, 5, 10, and 20 was $17.57ng/{\mu}g$ regardless of the reference count. The largest area under the curve value was obtained when the receiver operating characteristic curve was drawn using the eosinophil count of 2. Conclusion: Nasal eosinophil count was significantly associated with protein-corrected EPO.

• The Korean Journal of Applied Statistics
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• v.17 no.2
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• pp.327-336
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• 2004

Many researchers have used the robust variogram to reduce the effect of outliers in spatial data analysis. Recently it is known that estimating the variogram after replacing outliers is more efficient. In this paper, we suggest a new data cleaner for geostatistic data analysis and compare the efficiency of outlier cleaners.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.18 no.8
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• pp.1094-1101
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• 1993

We show that image compression possibilities of BDPCM which reduces information and increases correlation with signal-blurring. Under the same quantization steps, signal flow at the coder is analyzed and complete signal reconstruction properties are shown. Dynamic range characteristics of the differences by the conventional DPCM predictor are analyzed. In order to improve the median filter reduces impulse noise with blurring, adaptive filtering for the differences is proposed. By means of the difference range, transmission impulse noises are detected and corrected by the filtering. Therefore, low bit rate image codec with noise eliminations is proposed.

• Journal of Korean Critical Care Nursing
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• v.9 no.1
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• pp.40-50
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• 2016

Purpose: Continuous renal replacement therapy (CRRT) has become the preferred dialysis method to support critically ill children and neonates with acute kidney injury. Using CRRT on neonates has increased, but reports about experience are limited. The aim of this study is to describe the clinical application, outcomes, and complications of CRRT in children and neonates. Methods: A retrospective review was performed in 135 children and 36 neonates who underwent CRRT at a tertiary hospital from 2008 to 2015. Results: At the initiation of CRRT, the median age of children was 72 months and the corrected age of neonates was 37.1 weeks. Median body weight of neonates was 3.2 kg. In neonates, initial degree of fluid overload [FO%], blood flow rate [BFR] and ultrafiltration rate [UFR] rate during CRRT were higher than in children. Median real time of CRRT was 90.5 and 53.5 hours in children and neonates, respectively. Downtime of CRRT was 0.7 and 1.3 hours/day. Median mortality rates (44.4% vs.47.2%) and complication rates were similar between the groups. Conclusion: CRRT can be used for a wide range of critically ill children and neonates. Different application methods of CRRT can contribute to increased survival of neonates.

• 제어로봇시스템학회:학술대회논문집
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• 2003.10a
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• pp.789-792
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• 2003

Pipe inspection has a great importance to ensure safety for the nuclear power plant. In this paper, we designed visual inspection module for the tube internal, which diameter is 15${\sim}$20mm. And we made inspection module which consisted of CCD camera and light. And the relation between image and real world coordinate is established. Image processing is performed to calculate mapping parameter and analyze the size of defect. For the calculation of mapping parameter, experiment is performed using grid type test pattern. Acquired image is processed to extract image coordinate. Edge detection, thresholding, median filtering and morphology filtering is applied to extract grid pattern. Extracted image coordinate is used to calculate image to real world mapping. Lens distortion was considered and corrected to get exact data. Coordinate transformation data is provided for the users to recognize easily. Experiment was performed using grid type test pattern, we extracted lens distortion parameter and real coordinate of defect point. Radial distortion of lens was corrected but tangential distortion was not considered. As continuum to this study, the tangential distortion of lens is considered and improvement of analy zing technique for the tube internal be explored continuously.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.18 no.4
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• pp.238-245
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• 2015

Purpose: The aim of this study was to evaluate bolus transit during esophageal swallow (ES) and gastroesophageal reflux (GER) events and to investigate the relationship between the characteristics of ES and GER events in a population of term and preterm newborns with symptoms of gastroesophageal reflux disease (GERD). Methods: The study population consisted of term and preterm newborns referred to combined multichannel intraluminal impedance (MII) and pH monitoring for GERD symptoms. The frequency and characteristics of ES and GER events were assessed by two independent investigators. Statistical significance was set at p<0.05. Results: Fifty-four newborns (23 preterm) were included in the analyses. Median bolus head advancing time corrected for esophageal length (BHATc) was shorter during mealtime than during the postprandial period (median, interquartile range): 0.20 (0.15-0.29) s/cm vs. 0.47 (0.39-0.64) s/cm, p<0.001. Median bolus presence time (BPT) was prolonged during mealtime: 4.71(3.49-6.27) s vs. 2.66 (1.82-3.73) s, p<0.001. Higher BHATc (p=0.03) and prolonged BPT (p<0.001) were observed in preterm newborns during the postprandial period. A significant positive correlation between BHATc and bolus clearance time was also observed (${\rho}=0.33$, p=0.016). Conclusion: The analysis of ES and GER events at the same time by MII provides useful information to better understand the physiopathology of GERD. In particular, the analysis of BHATc during the postprandial period could help clinicians identify newborns with prolonged esophageal clearance time due to impaired esophageal motility, which could allow for more accurate recommendations regarding further tests and treatment.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.23 no.1
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• pp.20-26
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• 2013

Objectives: This study was conducted to evaluate the health risk of workers exposed to butyl glycidyl ether to prevent them from developing occupational diseases. Methods: The workplaces that coat floor with epoxy were selected and the samples were collected and analyzed with NIOSH 1616 Method. We calculate workplace reference concentration using with NOAEL estimated by the study of Anderson et al. in 1978. Risk was calculated by the ratio of exposure to workplace reference concentration. Monte-Carlo simulation was performed to derivate the median, cumulative 90%, and cumulative 95% value by using Crystal Ball. Results: Butyl glycidyl ether is a skin, eye irritator and can result in central nervous system depression, allergic reaction. NOAEL was 38 ppm and workplace reference concentration was calculated as 0.73 ppm corrected with uncertainty factors. Geometric mean was 1.152 ppm and geometric standard deviation was 1.522 by the workplace environment measurement. The median, cumulative 90%, and cumulative 95% value of risk were calculated as 1.617, 1.934, and 2.092, respectively. Conclusions: Not only cumulative 90% and cumulative 95% value but also the median of risk is higher than 1.0 by the risk characterization, so it can do a lot of harm to workers. Therefore, the process of derivating workplace reference concentration and the appropriacy of the uncertainty factors should be re-examined.

• Journal of The Korean Astronomical Society
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• v.27 no.2
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• pp.119-132
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• 1994

The BVR CCD photometry was performed for the globular cluster M13 down to $V=19^m$ over the region from the center to the west 13 arcmin and the CMD of M13 is investigated. The major photometric error in the crowded field which is due to the variation in the sky background was corrected by the median filtering method and the direct sky method. Some characteristics of the CMD of M13 obtained in the present study are as follows: Firstly, the distribution of stars on the CMD is well consistent with the mean lines of Sandage(1970) along the red giant branch(RGB), horizontal branch(HB) and asymtotic giant branch(AGB). Secondly, some gaps exists along the RGB and blue horizontal branch(BHB). Thirdly, the UV-bright stars are more concentrated at the inner region of the cluster.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1044-1053
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• 2021

Objective: Motion-corrected averaging with a single-shot technique was introduced for faster acquisition of late-gadolinium-enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging while free-breathing. We aimed to evaluate the image quality (IQ) of free-breathing motion-corrected single-shot LGE (moco-ss-LGE) in patients with hypertrophic cardiomyopathy (HCM). Materials and Methods: Between April and December 2019, 30 patients (23 men; median age, 48.5; interquartile range [IQR], 36.5-61.3) with HCM were prospectively enrolled. Breath-held single-shot LGE (bh-ss-LGE) and free-breathing moco-ss-LGE images were acquired in random order on a 3T MR system. Semi-quantitative IQ scores, contrast-to-noise ratios (CNRs), and quantitative size of myocardial scar were assessed on pairs of bh-ss-LGE and moco-ss-LGE. The mean ± standard deviation of the parameters was obtained. The results were compared using the Wilcoxon signed-rank test. Results: The moco-ss-LGE images had better IQ scores than the bh-ss-LGE images (4.55 ± 0.55 vs. 3.68 ± 0.45, p < 0.001). The CNR of the scar to the remote myocardium (34.46 ± 11.85 vs. 26.13 ± 10.04, p < 0.001), scar to left ventricle (LV) cavity (13.09 ± 7.95 vs. 9.84 ± 6.65, p = 0.030), and LV cavity to remote myocardium (33.12 ± 15.53 vs. 22.69 ± 11.27, p < 0.001) were consistently greater for moco-ss-LGE images than for bh-ss-LGE images. Measurements of scar size did not differ significantly between LGE pairs using the following three different quantification methods: 1) full width at half-maximum method; 23.84 ± 12.88% vs. 24.05 ± 12.81% (p = 0.820), 2) 6-standard deviation method, 15.14 ± 10.78% vs. 15.99 ± 10.99% (p = 0.186), and 3) 3-standard deviation method; 36.51 ± 17.60% vs. 37.50 ± 17.90% (p = 0.785). Conclusion: Motion-corrected averaging may allow for superior IQ and CNRs with free-breathing in single-shot LGE imaging, with a herald of free-breathing moco-ss-LGE as the scar imaging technique of choice for clinical practice.