• BMB Reports
• /
• v.42 no.5
• /
• pp.286-292
• /
• 2009

Arginine deiminase (ADI), an arginine-degrading enzyme, has anti-proliferative and anti-tumor activities and is capable of inhibiting the production of nitric oxide (NO). Modulation of nitric oxide (NO) production is considered a promising approach for the treatment of various diseases including cancer, inflammation and neuronal disorders. In this study, an ADI gene was fused with an HIV-1 Tat peptide in a bacterial expression vector to produce an genetic in-frame Tat-ADI fusion protein. When added exogenously to the culture media, the expressed and purified Tat-ADI fusion proteins were efficiently transduced into macrophage Raw 264.7 cells in a time- and dose-dependent manner. Furthermore, transduced Tat-ADI fusion proteins markedly increased cell viability in cells treated with lipopolysaccharide (LPS). This increase in viability was mediated by an inhibition of NO production. These results suggest that this Tat-ADI fusion protein can be used in protein therapies of NO-related disorders such as cancer, inflammation and neuronal diseases.

• The Journal of the Korea Contents Association
• /
• v.11 no.8
• /
• pp.211-220
• /
• 2011

The study conducted a survey on the perception level for radiological technologists with 321 nurses and auxiliary nurses working at university hospitals in Busan in order to supply preliminary data to enhance the status as well as professional images of radiological technologists. The result shows the perception level of $3.02{\pm}0.42$ with the highest score for the professional image and the lowest score for the business image. By question, 'they are professional' gets the highest score while 'they understand problems of patients well' gets the lowest. Among respondents, those who are well aware of education courses as well as leading organization of examination and who answer as a health care provider or a medical technician under the medical law show a high level of perception while those who answer as technician show a low perception level. Those who agree with radiologists as a career and consider their status as high in medical institutions have a high level of perception. In order to improve the perception level, individuals as well as associations' promotion and strategies are required to fix the title and enhance the negative images through active interests and kind attitudes toward patients. Also, efforts to escape from previous images limited to technical colleges, to vitalize academic conference and remedial education, and to frame the law of professional radiological technologists system are asked to heighten the qualification and status of radiological technologists. More than that, advertising and monitoring via mass media are needed to develop the image as professional career men as well.

• Journal of Broadcast Engineering
• /
• v.16 no.3
• /
• pp.510-519
• /
• 2011

Intra mode decision is a useful coding tool in Distributed Video Coding (DVC) for improving DVC coding efficiency for video sequences having fast motion. A major limitation associated with the existing intra mode decision methods, however, is that its efficiency highly depends on user-specified thresholds or modeling parameters. This paper proposes an entropy-based method to address this problem. The probabilities of intra and Wyner?Ziv (WZ) modes are determined firstly by examining correlation of pixels in spatial and temporal directions. Based on these probabilities, entropy of the intra and the WZ modes are computed. A comparison based on the entropy values decides a coding mode between intra coding and WZ coding without relying on any user-specified thresholds or modeling parameters. Experimental results show its superior rate-distortion performance of improvements of PSNR up to 2 dB against a conventional Wyner?Ziv coding without intra mode decision. Furthermore, since the proposed method does not require any thresholds or modeling parameters from users, it is very attractive for real life applications.

• Journal of Internet Computing and Services
• /
• v.19 no.2
• /
• pp.77-88
• /
• 2018

In order to prevent cervical cancer, free vaccination against cervical cancer(HPV vaccine) for 12-year-old girls has been ongoing since June 2016. The purpose of this study is to investigate how the media reported the risk information of HPV vaccine side effects and to suggest implications for government's risk communication and policy PR. The time frame was divided into two stages, stage 1(policy formation stage, 6 months before the start of free HPV vaccination) and stage 2(policy execution stage, 6 months after the free HPV vaccination was implemented). A total of 314 news articles on HPV vaccine safety and HPV Vaccine side effects were analyzed by content analysis and network analysis. The number of articles increased at stage 2 and the Centers for Disease Control and Prevention emphasized the safety of HPV vaccine and encouraged the inoculation while highlighting the effectiveness of the vaccine. Regarding HPV vaccine side effects, cases against vaccination in Japan were mainly reported at stage 1, whereas cases of HPV vaccine side effects from other countries such as Europe and USA were frequently reported at stage 2. In order to increase vaccination rate of HPV vaccine, it is time to take a strategic approach to prevent vague fear or anxiety about the vaccine.

• Journal of Broadcast Engineering
• /
• v.5 no.1
• /
• pp.113-122
• /
• 2000

It is sometimes necessary to remove the captions and recover original images from video images already broadcast, When the number of images requiring such recovery is small, manual processing is possible, but as the number grows it would be very difficult to do it manually. Therefore, a method for recovering original image for the caption areas in needed. Traditional research on image restoration has focused on restoring blurred images to sharp images using frequency filtering or video coding for transferring video images. This paper proposes a method for automatically recovering original image using BMA(Block Matching Algorithm). We extract information on caption regions and scene change that is used as a prior-knowledge for recovering original image. From the result of caption information detection, we know the start and end frames of captions in video and the character areas in the caption regions. The direction for the recovery is decided using information on the scene change and caption region(the start and end frame for captions). According to the direction, we recover the original image by performing block matching for character components in extracted caption region. Experimental results show that the case of stationary images with little camera or object motion is well recovered. We see that the case of images with motion in complex background is also recovered.

• Korean journal of communication and information
• /
• v.40
• /
• pp.249-286
• /
• 2007

This study examines the main characteristics and differences on people's page in selected four national dailies, such as Chosun Ilbo, Joongang Ilbo, Seoul Shinmum and Hankyoreh Shinmun. Both Chosun Ilbo and Joongang Ilbo are categorized as the conservatives; while Seoul Shinmum and Hankyoreh Shinmun as the progressive. This study has been done by applying methods of content analysis to reveal the differences in terms of people's occupations, types of reports, their philosophies, and standards of selecting people by the dailies for the people's pages. The results shows that the conservative newspapers are very similar to the progressive newspapers in terms of occupations and the types of reports, covering the people on people's pages. More specifically, both the conservative dailies and the progressive dailies report the people for whose jobs are related to both social and cultural works. However, the conservative newspapers have much more coverages than the progressive papers in terms of the publicity reporting on the people. The conservatives are also much more reports on the people who are eager to economic success than the progressive dailies; while the progressives papers have much coverages on those who are interesting in helping others than the conservatives papers. Finally, this study reveals that the conservative dailies mainly cover those who are in publicity activities and social elite groups, while the progressive newspapers are the social celebrities and persons of fame in society.

• BMB Reports
• /
• v.41 no.7
• /
• pp.537-541
• /
• 2008

Epilepsy is characterized by the presence of spontaneous episodes of abnormal neuronal discharges and its pathogenic mechanisms remain poorly understood. Recently, we found that the expression of creatine kinase (CK) was markedly decreased in an epilepsy animal model using proteomic analysis. A human CK gene was fused with a HIV-1 Tat peptide to generate an in-frame Tat-CK fusion protein. The purified Tat-CK fusion protein was efficiently transduced into PC12 cells in a time- and dose-dependent manner when added exogenously to culture media. Once inside the cells, the transduced Tat-CK fusion protein was stable for 48 h. Moreover, the Tat-CK fusion protein markedly increased endogenous CK activity levels within the cells. These results suggest that Tat-CK provides a strategy for the therapeutic delivery of proteins in various human diseases including the delivery of CK for potential epilepsy treatment.

• Journal of Science and Technology Studies
• /
• v.14 no.2
• /
• pp.127-164
• /
• 2014

This essay examines the motivations, goals, and assumptions of those who are participating in the appropriate technology movement in contemporary South Korea. In addition to analyzing books, articles, presentation materials, and media reports written by or about the "appropriate technologists," I have interviewed a few of them to hear their thoughts on appropriate technologies as well as inappropriate technologies. They choose to work on appropriate technology out of their good will for people in need, their Christian faith, and their pride in Korea's rapid and successful development. As a result, the appropriate technology movement in Korea does not engage in a critical evaluation of current sociotechnical systems, but instead takes an ethical and paternalistic stance in accepting and improving the given situation. Its apolitical character is effective in drawing a large number of participants, but it also limits their imagination and the movement's potential influence. Moreover, the movement's focus on "the other 90%" leads the participants to frame appropriate technology as something for "them" or "locals" rather than as something for "all of us." This essay concludes by suggesting that the appropriate technology movement in Korea should expand its scope from an ethical pursuit of technology to a political engagement with technology.

• Journal of Families and Better Life
• /
• v.2 no.1
• /
• pp.93-109
• /
• 1984

The purpose of this study is to investigate the direction and strategy of education for sex role concepts of children on the basis of factor analysis of the present situation in sex role concepts and their formation. Although some maintain that sex role concept of our society has been changing slowly, the traditional sex role concept still dominates and is potentially immanent. the analysis of present condition of our society indicates that the formal as well as informal education are facing with various crucial problems in providing the direction of behavior demanded for carrying out the role. The close analysis of the three theories, psychoanalytic theory , social learning theory, cognitive development theory, lends a support to the laim of the study that cognitive development theory provide an integrated frame of reference for us to see the sex role education analytically Furthermore, the factors which are found to have influences on the formation of sex role have been analyzed in three areas: Family, School and society. 1)The factors in family such as parental behavior of upbringing and their concepts of sex role have a direct relationship with the nature of sex tole concept of children. Therefore, the first step to make children to habe a new type of sex-role conception appropriate for modern societies is to change that of parental conception and attitudes. 2)the quantitative as well as the qualitative aspects of school education showed no exceptional trend from the dominant conception of the society, although school are expected to lead the society as formal education institution rather than just reflect the society. The educational activities and contents such as the conceived goal of education for eoch sex, textbook constitation, teaching behavior and sex-role concepts of teacher are found to be still dominated by the traditional sex-role assumption. 3) The social factors that have direct relationship with children's sex-role formation are social and cultural, which include social milieu, condition of employment, family structure and mass-media. Since family and school do not educate the young in a social vacuum. their educational function of sex-role formation are doomed to be limited and determined by these social factors. Unfortunately, the analysis of present conditions showed the dominance of traditional types of sex-role concepts in all these social factors. The education of sex-role concept for children should be treated as one of the most crucial value problems related with many other important problems, such as direction and patterns of behaviors of each sex, the degree of self-development and capabilities, and consequently human right, equality, humanization and the quality of happiness. Neverthless, the analysis of researches on sex-role education which have been surveyed in this study lead to a conclusion that concerted effort to change the education, formal as well as informal should be provided in every aspect of social life. If the sex role education of the past has aimed at the "feminization"of girls which indoctrinate girls into a limited and fixed role of house wives, the new education in the future should be directed foward "humanization" of both sexes which opens the diversity of roles for both boys and girl on equal levels and provide future possibilities in accordance to their individual capabilities and interests.

• Journal of Broadcast Engineering
• /
• v.10 no.3
• /
• pp.413-421
• /
• 2005

As the population of HDTV is growing, among many useful features of modern set top boxes (STBs) or digital video recorders (DVRs), video browsing, visual bookmark, and picture-in-picture capabilities are very frequently required. These features typically employ reduced-size versions of video frames, or thumbnail images. Most thumbnail generation approaches generate DC images directly from a compressed video stream. A discrete cosine transform (DCT) coefficient for which the frequency is zero in both dimensions in a compressed block is called a DC coefficient and is simply used to construct a DC image. If a block has been encoded with field DCT, a few AC coefficients are needed to generate the DC image in addition to a DC coefficient. However, the bit length of a codeword coded with variable length coding (VLC) cannot be determined until the previous VLC codeword has been decoded, thus it is required that all codewords should be fully decoded regardless of their necessary for DC image generation. In this paper, we propose a method especially for fast DC image generation from an I-frame using multiple-symbol lookup table (mLUT). The experimental results show that the method using the mLUT improves the performance greatly by reducing LUT count by 50$\%$.