• 대한기계학회논문집A
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• 제33권7호
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• pp.629-636
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• 2009

Mechanical stimulation is known to play a vital role on the differentiation of mesenchymal stem cells (MSCs) to pre-osteoblasts. In this research, we developed a tensile cell stimulator, composed of a DC motor-driven actuator and LVDT sensor for measuring linear displacement, to study the effects of tensile stress on osteogenic differentiation of MSCs. First, we demonstrated the reliability of this device by showing the uniform strain field in the silicon substrate. Secondly, we investigated the effects of tensile stretching on osteogenic differentiation. We imposed a pre-set cyclic strain at a fixed frequency on cell monolayer cultured on a flexible silicon substrate while varying its amplitude and duration. 60 min of resting period was allowed between 30 min of cyclic stretching and this cycle is repeated up to 7 days. Under the combined stimulation with osteogenic media and mechanical stretching, the osteogenic markers such as alkaline phosphatase (ALP), osterix, and osteopontin began to get expressed as early as 4 days of stimulation, which is much shorter than what is typically required for osteogenic media induced differentiation. Moreover, different markers were induced at different magnitudes of the applied strains. Lastly, for the case of ALP, we observed the antagonistic effects of osteogenic media when combined with mechanical stretching.

• 한국융합학회논문지
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• 제12권11호
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• pp.207-220
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• 2021

최근 센서 경험을 위한 새로운 매체들의 발전은 프로젝션맵핑, 가상현실과 같은 비디오 설치 미술의 시각적 표현을 더욱 확장시키고 있다. 예술가들은 새로운 매체들들 통해 새로운 시각적 표현 기법을 개발하고 발전시킬 수 있다. 프로젝션맵핑 기술은 지속적으로 미디어아트 작품의 시각적 표현에 다양한 가능성을 부여하고 있다. 본 논문은 프로젝션맵핑 기술에 기반한 시각 표현이 인간의 감각 체험으로 전이되고 확장되는 과정을 연구하기 위해서, 매체가 갖는 '복제성,' '전파성,' '가상성' 그리고 '인터랙션'의 특징을 분석함으로써 시각적 표현을 정의하고 의미를 기술하였다. 작품 분석을 통해 '반복과 중첩,' '시뮬라이크롬과 은유,' '치환과 전환'의 시각적 표현 기법에 대해 분석하고, 프로젝션맵핑 작품인 에 적용함으로써 시각 표현 기법이 인간의 감각 체험으로 확장되는 과정을 연구하였다. 시각적 표현의 확장성 연구는 작품을 제작하는 예술가들이나 관람하는 관객들에게 작품의 의미를 전달하거나 해석하는데 필요한 핵심 요소이다.

• Geomechanics and Engineering
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• 제23권3호
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• pp.217-225
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• 2020

In this paper, the thermoelastic interactions in a two-dimension porous body are studied. This problem is solved by using the Green and Lindsay (GL) generalized thermoelasticity model under fractional time derivative. The derived approaches are estimated. with numeral results which are applied to the porous mediums in simplifying geometrical. The bounding plane surface of the present half-space continuum is subjected to a pulse heat flux. We use the Laplace-Fourier transforms methods with the eigenvalues approach to solve the problem. The numerical solutions for the field functions are obtained numerically using the numerical Laplace inversion technique. The effects of the fractional parameter and the thermal relaxation times on the temperature field, the displacement field, the change in volume fraction field of voids distribution and the stress fields have been calculated and displayed graphically and the obtained results are discussed.

• Structural Engineering and Mechanics
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• 제73권6호
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• pp.725-735
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• 2020

The present investigation deals with the thermomechanical interactions in an orthotropic thermoelastic homogeneous body in the context of fractional order theory of thermoelasticity due to time harmonic sources. The application of a time harmonic concentrated and distributed sources has been considered to show the utility of the solution obtained. Assuming the disturbances to be harmonically time dependent, the expressions for displacement components, stress components and temperature change are derived in frequency domain. Numerical inversion technique has been used to determine the results in physical domain. The effect of frequency on various components has been depicted through graphs.

• Advances in aircraft and spacecraft science
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• 제4권6호
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• pp.711-727
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• 2017

This article is concerned with a two-dimensional problem of micropolar generalized thermoelasticity for a half-space whose surface is traction-free and the conductive temperature at the surface of the half-space is known. Theory of two-temperature generalized thermoelasticity with phase lags using the normal mode analysis is used to solve the present problem. The formulas of conductive and mechanical temperatures, displacement, micro-rotation, stresses and couple stresses are obtained. The considered quantities are illustrated graphically and their behaviors are discussed with suitable comparisons. The present results are compared with those obtained according to one temperature theory. It is concluded that both conductive heat wave and thermodynamical heat wave should be separated. The two-temperature theory describes the behavior of particles of elastic body more real than one-temperature theory.

• 대한기계학회논문집A
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• 제33권6호
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• pp.552-559
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• 2009

The effect of porosity on the crack propagation is studied by using the cohesive zone model. Standard mode I fracture test were done by using compact tension specimens with various porosities. Load-load line displacement curves and ${\delta}_5$-crack resistance curves for various porosities were obtained from experiments. The cohesive zone model proposed by Xu and Needleman was employed to describe the crack propagation in porous media, and the Gurson model is used for constitutive relation of porous materials. These models were implemented into user subroutines of a finite element program ABAQUS. The fracture mode changes from ductile fracture to brittle fracture as the porosity increases. Numerical calculations agree well with experimental results.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2002년도 추계학술대회논문집
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• pp.1015-1021
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• 2002

Optical disk is the media which is used generally in data storage device, but it has a disadvantage in the vibration by spinning and the shock. For overcoming these disadvantage, we must control the optical disk to minimize the focusing error and tacking error. The present study investigates the disk profile for minimizing the focusing error subjected to environmental shock and weight of the disk. In this study, the disk is assumed to be a cantilever beam to determine the disk profile for the minimum displacement as to the shock considering only the first mode. Also, for the optimally determined profile by ADS program this paper recalculate the robust caltilever profile by using orthogonal array and ANOM.

• Structural Engineering and Mechanics
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• 제49권1호
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• pp.41-64
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• 2014

The main objective of this article is the exploitation of a stochastic hybrid mesh-free method based on stochastic generalized finite difference (SGFD), Newmark finite difference (NFD) methods and Monte Carlo simulation for thermoelastic wave propagation and coupled thermoelasticity analysis based on GN theory (without energy dissipation). A thick hollow cylinder with Gaussian uncertainty in mechanical properties is considered as an analyzed domain for the problem. The effects of uncertainty in mechanical properties with various coefficients of variations on thermo-elastic wave propagation are studied in details. Also, the time histories and distribution on thickness of cylinder of maximum, mean and variance values of temperature and radial displacement are studied for various coefficients of variations (COVs).

• Structural Engineering and Mechanics
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• 제26권5호
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• pp.545-556
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• 2007

In this paper, a hybrid boundary element technique is implemented to analyze nonlinear transient pile soil interaction in Gibson type nonhomeogenous soil. Inelastic modeling of soil media is presented by introducing a rational approximation to the continuum with nonlinear interface springs along the piles. Modified $\ddot{O}$zdemir's nonlinear model is implemented and systems of equations are coupled at interfaces for piles and pile groups. Linear beam column finite elements are used to model the piles and the resulting governing equations are solved using an implicit integration scheme. By enforcing displacement equilibrium conditions at each time step, a system of equations is generated which yields the solution. A numerical example is performed to investigate the effects of nonlinearity on the pile soil interaction.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2001년도 춘계학술대회 논문집
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• pp.136-143
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• 2001

In this study, a numerical analysis for soil-pile interaction systems in multi-layered half planes under a forced vibration is presented. The soil-pile interaction system is divided into two parts, so called near field and far field. The near field soil using finite elements and piles using beam elements are modeled. The far field soil media is implemented using boundary elements those can automatically satisfy the condition of wave radiation. These two fields are numerically coupled by imposing displacement compatibility condition at the interface between the near field and the far field. For the verification, the forced vibration test was simulated and the response under horizontal and vertical harmonic loads at the pile cap in the layered half plane was determined. The results are compared to the theoretical and experimental results of the literatures to verify the proposed soil-pile interaction analysis formulation.