• Journal of Periodontal and Implant Science
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• v.31 no.2
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• pp.299-315
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• 2001

Application of membranes for guided tissue regeneration(GTR) have been confined to the subgingival barrier functions; however, many studies have provided evidence that some drugs, including tetracycline, initially can promote the growth of periodontal ligament or alveolar bone in peridontal therapy. Osseous regeneration in periodontal defects is increased by local administration of tetracycline due to its anti-collagenolytic effect, which enhances bone-forming ability via osteoblast cell chemotaxis and reduced bone resorption. The aim of this study was to evaluate effects of tetracycline loaded poly-L-lactide(PLLA) barrier membranes for guided bone regenerative potential. Tetracycline was incorporated into the PLLA membrane with the ratio 10% to PLLA by weight. Ability to guided bone regeneration of the membranes were tested by measuring new bone in the tibial defects($7{\times}10{\times}5\;mm^3$) of the beagle dog for 4,5, and 6 weeks. In control, drug-unloaded PLLA membranes were used in same size of defect. In histologic finding of the defect area, a few inflammatory cells were observed in both groups. These membrane were not perforated by connective tissue and maintained their mechanical integrity for the barrier function for 4-6 weeks. New bone formation was greater in defects covered by tetracycline-loaded membrane than in defects covered by drug- unloaded membranes. In bone regeneration guiding potential test, tetracycline-loaded membrane was more effective than drug- unloaded membranes(p<0.05). These results suggest that tetracycline-loaded PLLA membranes potentially enhance guided bone regenerative efficacy and might be a useful barrier for GTR in periodontal treatment.

• Journal of the Korean Society of Safety
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• v.26 no.1
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• pp.1-7
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• 2011

When the pumps stopped in the operation by the power failure, the hydraulic transients take place in the sudden change of a velocity of pipe line. Each and every water hammer problem shows the critical stage to be greatly affected the facts of safety and reliability in case of power failure. The field tests of the water hammer executed at Cheong-Yang booster pump station having an air chamber. The effects were studied by both the practical experiments and the CFD(Computational Fluid Dynamics : Surge 2008). The result states that the system with water hammering protection equipment was much safer when power failure happens. The following data by a computational fluid dynamic analysis are to be shown below, securing the system stability and integrity. (1) With water hammering protection equipment. (1) Change of pressure : Up to $15.5\;kg/cm^2$ in contrary to estimating $16.88\;kg/cm^2$. (2) Change rate of water level : 52~33% in contrary to estimating 55~27%. (3) Note that the operational pressure of pump runs approx. 145 m, lowering 155 m of the regularity head of pump. (4) Note that the cycle of water hammering delays from 80 second to 100 second, together with easing the function of air value at the pneumatic lines. (2) Change of pressure without water hammering protection equipment : Approximate $22.86\;kg/cm^2$. The comprehensive result says that the computational fluid dynamics analysis would match well with the practical field-test. It was able to predict Max. or Min. water hammering time in a piping system. This study aims effectively to alleviate water hammering in a pipe line to be installed with air chamber at the pumping station and results in making the stability of pump system in the end.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.1
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• pp.1-6
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• 2013

Three Surface cracks are among the more common flaws in aircraft and pressure vessel components. Accurate stress intensity analyses and crack growth rate data of surface-cracked components are needed for reliable prediction of their fatigue life and fracture strengths. Three Dimensional finite element method (FEM) was used to obtain the stress intensity factor for surface cracks existing in structures. A geometry model, i.e. a solid containing one or several 3D cracks is defined. Nodes are generated by bucket method, and quadratic tetrahedral solid elements are generated by the Delaunay triangulation techniques. To examine accuracy and efficiency of the present system, the stress intensity factor for a semi-elliptical surface crack in cylindrical structures subjected to pressure is calculated. Analysis results by present system showed good agreement with those by ASME equation and Raju-Newman's equation.

• Journal of the Korean Institute of Gas
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• v.12 no.2
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• pp.57-62
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• 2008

Difference of failure modes was studied by finite element analysis for elbows with local wall thinning area particularly at inner surface of intrados of the elbow. Longitudinal wall thinning length, minimum thickness were kept constant but circumferential wall thinning width was varied to get $90^{\circ}$, $180^{\circ}$ and $360^{\circ}$ thinning width. Elastic-plastic analysis were carried out under the combined loading conditions of internal pressure and in-plane bending moment closing the elbow. Von Mises stress were obtained from the outer surface central surface location in intrados, extrados and crown parts in elbow. The results showed that the plastic deformation and failure started from the crown location when the thinning width small ($90{\sim}180^{\circ}$). However, plastic collapse started from the intrados location when the thinning width is approaching $360^{\circ}C$. This should be reflected to assess structural integrity of elbows after wall thinning measurement is made.

• Journal of the Korean Institute of Gas
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• v.24 no.4
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• pp.10-17
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• 2020

The structural reliability assessment can be used to improve the reliability in the asset integrity management of the pipeline by using a geometric variation, mechanical characteristics, load change and operating condition as evaluation factors. When evaluating structural reliability, the failure probability of the natural gas pipe is evaluated by the relationship of the resistance of the pipe material to external loads. The failure probability of the natural gas pipe due to the combined stresses such as the internal pressure, thermal stress and bending stress was evaluated by using COMREL program. When evaluating the failure probability of the natural gas pipe, a buried depth of 1.5 to 30 m, a wheel load of 2.5 to 20 ton, a temperature difference of 45℃, an operating pressure of 6.86MPa, and a soil density of 1.8 kN/㎥ were used. The failure probabilities of the natural gas pipe were evaluated by the Von-Mises stress criterion as the maximum allowable stress criterion under the combined stresses.

• International Journal of Highway Engineering
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• v.12 no.4
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• pp.139-145
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• 2010

An integrity testing for stone columns was attempted using crosshole S-wave logging. The method is conceptionally quite similar to the crosshole sonic logging (CSL) for drilled piers. The critical difference in the logging is the use of S-wave rather than P-wave, which is used in CSL, because swave is the only wave sensing the stiffness of slower unbounded materials than water. An electro-mechanical source, which can generate reversed Swave signals, was utilized in the logging. The stone column was delineated using the S-wave travel times across the stone column, the S-wave velocity profile of the crushed stone($V_{cs}$-profile) and that of surrounding soil($V_s$-profile). In the calculation of $V_{cs}$-profile of the crushed stone, its friction angle and Ko (coefficient of lateral earth pressure at rest) are recommended to be used. The calculation of the column diameter is not much affected by the values of friction angle and Ko.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2005.07a
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• pp.369-370
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• 2005

LTCC (Low Temperature Cofired Ceramic) technology is one of technologies which can realize SIP (System-In-a-Package). In this paper realization of gas sensor using LTCC technology was described. In the conventional gas sensor structure, wire bonding method is generally used as an interconnection method whereas in the LTCC sensor structure, via was used for the interconnection. As sensing materials, $SnO_2$ was adopted. The effect of frit glass portion on the adhesion of the sensing material to the LTCC substrate and the electrical conductivity of the sensing material were analyzed. AgPd, PdO, Pt was added to the sensing material as an additive for improving the gas sensitivity and electrical conductivity and the effect of the amount of additives in the sensing material on the electrical conductivity was investigated. The effect of the amount of frit glass in the termination on the sensor performance, especially mechanical integrity, was considered and the crack initiation and propagation in the boundary between the sensing material and the termination was studied.

• Journal of Korean Society of Steel Construction
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• v.26 no.1
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• pp.1-10
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• 2014

In this study, out-of-plane flexural test was performed to analyze behavior properties for a beam specimen which imitated a structure with connection member between reinforced concrete and steel plate concrete part. Tie bars between a upper and a lower steel plate, and tie wide flange shapes between upper and lower ribs were designed to prevent the steel plate or the ribs from breakaway in the connection of the specimen. As a result of the test, ductile failure behavior of the specimen and the functionality of the tie members were conformed as originally intended. Also, tension tests were performed to evaluate the design appropriateness of two specimens produced to anchor and connect mechanically #14 bars. The two test results showed that the anchorage connection system behaves in elastic limit during the main bars yielded, and the integrity of the designed system was verified.

• Journal of Korean Society of Steel Construction
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• v.23 no.4
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• pp.483-491
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• 2011

The fabrication of steel structural members always involves welding process such as flux cored arc welding. Therefore, for the application of structural steels to cold regions, it is a prerequisite to clarify the service temperature of the welded joints in order to ensure the structural integrity of the welded parts. In this study, the Charpy impact test was conducted to evaluate the service temperature of structural steel weld. The Charpy impact test is a commercial quality control test for steels and other alloys used in the construction of metallic structures. The test allows the material properties for service conditions to be determined experimentally in a simple manner with a very low cost. Standard V-notch Charpy specimens were prepared and tested under dynamic loading condition. The service temperatures of the weld metal, HAZ (heat affected zone) and base metal were derived by the absorbed energy and the impact test requirements; thus the applicability of the structural steels to cold regions was discussed in detail.

• Journal of Chest Surgery
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• v.25 no.7
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• pp.693-701
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• 1992

Extracorporeal cardiopulmonary bypass[CPB] has been associated with a wide variety of hematologic derangements, including a transient deformation and hemolysis of red blood cells[RBCs], which is supposed to be due to mechanical trauma and/or metabolic alterations. Since membrane integrity is, in part, maintained by energy requiring process, inadequate function of erythrocyte glycolytic pathway, which is inevitalble during CPB, may cause depletion of high energy phosphate pool and result in hemolysis. The authors performed an investigation to assess whether administration of Fructose-l, 6-diphsphate [FDP], which has been known to enhance intracellular glycolytic activities, could counteract erythrocyte hemolytic events caused by CPB. Sixty pateints with cyanotic congenital heart diseases, who underwent open heart surgery under CPB longer than 60 minutes, were randomly divided into two groups depending on whether use of FDP[Group FDP] or not[Group Control]. The age, sex, CPB time, preoperative hemoglobin level, disease entities were all similar[Table 1], and membrane type oxygenators were used in all patients. In Group, FDP, a dose of 250mg/kg body weight of FDP was administered by intravenous dripping every 12 hours from the morning of the operation to postoperative 48 hours, To demonstrate the degree and pattern of hemolysis of erythrocyte, reticulocyte count, indirect /direct bilirubin, haptoglobin, plasma hemoglobin, lactate dehydrogenase were measured every 12 hours from the time of cessation of CPB to 48 hours and RBC morphologic study, osmotic fragility test were done every 24 hours. All parameters revealed less hemolytic in group FDP [Fig. 1~5], though the differences between two groups were not significant, except plasma hemoglobin, lactate dehydrogenase changes. A pattern of sequential changes of plasma hemoglobin, lactate deh-ydrogenase showed the highest level at the time of CPB stop and abrupt decrease in following 24 hours in both groups, and statistically significant differences were demonstrated in group FDP at least for the first 12 hours postoperatively[p<0.05]. The authors conclude that they can expect the benificial effect of FDP on the maintenance of membrane stability of RBC probably by energy enhancement during the shock status of CPB, but FDP could not completely prevent the damaging effect on RBC by cardiopulmonary bypass