• Journal of Haehwa Medicine
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• v.29 no.2
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• pp.30-37
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• 2020

Objectives : In this case, the knee joint inconvenience with deteriorating pain has been relieved by acupuncture treatment for a patient was 51-year-old male with a left medial meniscal posterior horn rupture in 2012. Methods : Twenty-four times of acupuncture treatments were performed for Twelve weeks from July 2016 to improve the disease. SP8(Jigi; 地機), BL63(Geummun; 金門), KI3(Taegye; 太谿), LI4(Hapgok; 合谷) were chosen for treatment by principles of Traditional Korean Medicine. Results : Numeric Rating Scales, which means subjective pain, decreased from 6 points to 3 points out of 10 points in total. Pressure Pain Threshold, which means sensitivity to pressure applied to the affected area, increased from 21N to 47N on the lateral-inferior side and from 19N to 50N on the lateral side. K-WOMAC, which indicates discomfort of knee-related activity, was 56 points out of 96 points in total before treatment and 4 points after treatment, 13 points after two years, and 15 points after four years. However, MRI tests conducted before and after treatment did not identify any significant changes. As a result, we confirmed that a total of 24 acupuncture treatments had resulted in the relief objective and subjective pain and functional recovery, especially in the case of the knee function, maintained until after four years later. There was no significant substrate recovery in meniscal rupture.

• The Journal of Korean Obstetrics and Gynecology
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• v.31 no.2
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• pp.31-48
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• 2018

Objectives: This study was performed to observe the correlations between the results of ABR-2000 and DSOM / 3D-MAC to evaluate the feasibility of ABR-2000 as a oriental medical diagnostic criteria. Methods: We studied 547 women visiting ${\bigcirc}{\bigcirc}$ hospital from December 2012 to June 2015. The subjects were categorized in two groups, 'Hypotonia' and 'Non-Hypotonia' by the result of ABR-2000 and assessed the result of DSOM, 3D-MAC for each group. The differences of pulse wave factors by group also studied. Results: 1. There was no significant difference between two groups about the output frequency of pathogenic factors in DSOM while the result showed the higher correlation in Hypotonia group in terms of the companion tendency of pathogenic factors and syndromes formed by the combination of pathogenic factors. 2. The pulse waves of Hypotonia group were mostly slow, weak, tense and stiff than Non-Hypotonia group. Conclusions: 1. In Hypotonia group, yin deficiency (陰虛) factor was frequently accompanied and consumption (虛損) of various organs based on the yin deficiency (陰虛) was observed. It means chronic and severe condition of exhaustion syndrome (虛勞). 2. The result of 3D-MAC also means pathological feature of yin syndrome (陰 證) and consumption (虛損). Besides, lower scores of Body Surface Area (BSA), body weight, and Body Mass Index (BMI) were associated with body weakness (體瘦), a symptom of exhaustion syndrome (虛勞).

• Journal of Sasang Constitutional Medicine
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• v.16 no.3
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• pp.46-58
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• 2004

1. Objectives This study was performed by means of perceptual evaluation of the voices of Sasang Constitution. 2. Methods 73 female subjects were classified by means of 3 kinds of Questionnaire papers(QSCCII, QSCCI, Sasang Pattern Identification Questionnaire). So they were categorized into 3 groups, 23 Soyangin, 28 Taeumin and 22 Soeumin. 73 voice samples were presented three times to a group of 5 judges. The time interval between ratings was 14 days. The four goals of this study were to evaluate the intraobserver reliability between each rating, to evaluate the interobserver reliability, to evaluate the reliability between the each rating and Questionnaire result and to make the notion of the consensus of Sasang Constitution's Voice. 3. Results & Conclusions The intraobserver reliability between the first and second rating showed significance statistically among all observers. And the intraobserver reliability between the second and third rating showed significance except one observer. The interobserver reliability among the three ratings showed significance statistically except one to two observers in the first rating and other one to another one in the second rating. In the reliability between the each rating and Questionnaire result, one in the first rating, other one in the second rating and another two in the third rating showed significance. To make the notion of the consensus of Sasang Constitution's Voice, classification into 4 categories was made: clear/hoarse, high/low, fast/slow, powerful/powerless. The voice of Soyangin group was classified as powerful and fast, and that of Taeumin group as powerful, hoarse and low and that of Soeumin group as powerless and slow.

• Herbal Formula Science
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• v.22 no.2
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• pp.1-13
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• 2014

Objectives : ShangHanLun is a clinical guideline, and its core is in the part of Six-meridian Diseases. In recent philological sutdies, independent textual analysis of Shanghanlun is essential to define the scope of research. Methods : By the textual study, I defined the Shanghanlun clinic model. And I researched about medical range of Shanghanlun, and relations between Shanghanlun and JinGuiYaoLue, and between Shanghanlun and Huangdineijing. Results : In six topic sentences, the word '-之爲' means 'a process'. In provisions following topic sentences, the word '者' means 'a person'. So Shanghanlun is describing processing factors of Six-meridian Diseases and related human changes with clinical therapy. In the philological studies, meaning of '傷寒' was possibly just the 3rd provision of the greater yang disease part. Practically Shanghanlun's study range is over the concept of Cold damage today. Additionally Jinguiyaolue deals diseases, but Shanghanlun deals human. Gangpyeong-Shanghanlun's phrases can be separated into five part, and oldest part is independent of Huangdineijing. Conclusions : So we need to set a new and independent clinic model of Shanghanlun to verify it. The Shanghanlun's clinic model has a 3 steps. 1st step is to find 6 type defined symptoms, which act as processing factors of Six-meridian Diseases. 2nd step is to confirm a human changes after a Disease appeared. 3rd step is to treat a patient as a provision suggests. Philologically Shanghanlun's clinic range is not limited by the word '傷寒'. And many concepts in Shanghanlun should be independent of Huangdineijing.

• Korean Journal of Biological Psychiatry
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• v.25 no.2
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• pp.38-43
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• 2018

Objectives Dopamine dysregulation has been regarded as one of the core pathologies in patients with schizophrenia. Since dopamine synthesis capacity has found to be inconsistent in patients with schizophrenia, current classification of patients based on clinical symptoms cannot reflect the neurochemical heterogeneity of the disease. Here we performed new subtyping of patients with first-episode psychosis (FEP) through biotype-based cluster analysis. We specifically suggested basal ganglia structural changes as a biotype, which deeply involves in the dopaminergic circuit. Methods Forty FEP and 40 demographically matched healthy participants underwent 3T T1 MRI. Whole brain parcellation was conducted, and volumes of total 6 regions of basal ganglia have been extracted as features for cluster analysis. We used K-means clustering, and external validation was conducted with Positive and Negative Syndrome Scale (PANSS). Results K-means clustering divided 40 FEP subjects into 2 clusters. Cluster 1 (n = 25) showed substantial volume decrease in 4 regions of basal ganglia compared to Cluster 2 (n = 15). Cluster 1 showed higher positive scales of PANSS compared with Cluster 2 (F = 2.333, p = 0.025). Compared to healthy controls, Cluster 1 showed smaller volumes in 4 regions, whereas Cluster 2 showed larger volumes in 3 regions. Conclusions Two subgroups have been found by cluster analysis, which showed a distinct difference in volume patterns of basal ganglia structures and positive symptom severity. The result possibly reflects the neurobiological heterogeneity of schizophrenia. Thus, the current study supports the importance of paradigm shift toward biotype-based diagnosis, instead of phenotype, for future precision psychiatry.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.62-70
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• 2011

Objectives: The purpose of this study is to investigate the relationship between cold hypersensitivity and common health indexes including dyspepsia, headache, defecation, leucorrhea, and menstruation in young women. Methods: 40 outpatients who visited Kangnam Kyung-Hee Oriental Hospital from January, 2010 to November, 2011 were analyzed. The experimental group consisted of 20 patients diagnosed with cold hypersensitivity, while the control group consisted of 20 patients who were not. All patients were subjected to Digital Infrared Thermal Imaging(DITI), and those with thermal difference greater than $2^{\circ}C$ between anterior thigh and top of feet were diagnosed with cold hypersensitivity. The subjective characteristics of dyspepsia, headache, defecation, leucorrhea, and menstruation were obtained through inquiry by residents at the hospital. The relationship between cold hypersensitivity, dyspepsia, headache, defecation, leucorrhea, and menstruation was analyzed with Independent T-test using SPSS for Windows (version 17.0). Results: Means of defecation, leucorrhea, dysmenorrhea in cold hypersensitivity group were higher than control group without significant statistical difference. Dyspepsia appeared statistically higher in experimental group with significance while headache was the same in both groups. Means of menstrual cycle and menstrual coagulation were higher in non-cold hypersensitivity group, but there was no statistical difference. Conclusions: Results suggest that dyspepsia is common in cold hypersensitivity and treatment of cold hypersensitivity may relieve accompanying digestive problems.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.23 no.1
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• pp.35-40
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• 2013

Objectives: Asbestos contents of crushed serpentine rocks and airborne fiber concentrations of workers were determined at two serpentine quarries and a steel mill. Methods: Bulk samples of uncrushed and crushed serpentine rocks were collected and analyzed by PLM and TEM. Airborne asbestos samples were collected from the breathing zone of workers and the vicinity of working area and analyzed by PCM and TEM. Results: Chrysotile was identified with antigorite, lizardite and non-asbestiform actinolite in bulk samples. The arithmetic means of chrysotile contents in crushed serpentines were 0.11, 0.01, 0.42%(W/W) by quarry A, quarry B and a steel mill, respectively. The asbestos concentrations of all personal samples were less than 0.1 f/cc which is the permissible exposure limit of workers in Korea. The arithmetic means of airborne asbestos concentrations were 0.017 f/cc and 0.009 f/cc in personal samples collected from two serpentine quarries. The asbestos concentrations of all personal samples collected from a steel mill were less than LODs by PCM analysis but asbestos was detected in area samples by TEM. By the job tasks of serpentine quarries, crusher/separator operation generated the highest exposure to airborne asbestos. Conclusions: Although chrysotile contents in crushed serpentines of quarries were less the permissible level, the highest exposure of workers in serpentine quarries reached up to 76% of the permissible level of airborne asbestos. There were also possibilities of occupational exposure to airborne asbestos in a steel mill. The present exposure study should encourage further survey and occupational control of quarries producing serpentine or other types of asbestos-bearing rocks.

• The Journal of Internal Korean Medicine
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• v.41 no.6
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• pp.1141-1161
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• 2020

Objectives: Parkinson's disease (PD) is a neurodegenerative disease of the elderly characterized by impaired behavior from lack of dopamine secretion. However, no accurate quantitative diagnosis method has been established. The purpose of this study was to analyze the patent trends (PTs) of health examination and daily monitoring/healthcare technology for PD. Methods: For analyzing PTs, a search summary for classifying each analysis target technology was set, and a final search formula was constructed by collecting keywords. After constructing a database of related patents through the final search formula, noise was removed to extract valid patents. PTs by major countries were analyzed using the valid patents, and PTs and growth stages were analyzed by the detailed technologies. Results: The survey analysis showed that, despite the existence of unpublished patents between 2018 and 2020, patent activity has increased rapidly in the recent period, and this increasing trend was led by the USA. This technology is considered to be in its early- or mid-stage growth period, which means that the marketability is high and the barriers are low. Korea's market share is only about 25%, but it has a larger number of applications than those of Europe and Japan. Integrated monitoring and diagnosis technologies for PD have a share of 34%. Conclusion: The advances in diagnosis and healthcare technology for PD means that traditional Korean medicine must continue to pay attention to related technologies and to review plans that are applicable to clinical practice.

• Journal of Korean Medicine for Obesity Research
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• v.21 no.2
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• pp.80-94
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• 2021

Objectives: The purpose of this study is to re-evaluate the importance of questions of obesity syndrome differentiation (OSD) questionnaire based on real-world survey and to explore the possibility of simplifying OSD types. Methods: The OSD frequency was identified, and variance threshold feature selection was performed to filter the questions. Filtered questions were clustered by K-means clustering and hierarchical clustering. After principal component analysis (PCA), the distribution patterns of the subjects were identified and the differences in the syndrome distribution were compared. Results: The frequency of OSD in spleen deficiency, phlegm (PH), and blood stasis (BS) was lower than in food retention (FR), liver qi stagnation (LS), and yang deficiency. We excluded 13 questions with low variance, 7 of which were related to BS. Filtered questions were clustered into 3 groups by K-means clustering; Cluster 1 (17 questions) mainly related to PH, BS syndromes; Cluster 2 (11 questions) related to swelling, and indigestion; Cluster 3 (11 questions) related to overeating or emotional symptoms. After PCA, significant different patterns of subjects were observed in the FR, LS, and other obesity syndromes. The questions that mainly affect the FR distribution were digestive symptoms. And emotional symptoms mainly affect the distribution of LS subjects. And other obesity syndrome was partially affected by both digestive and emotional symptoms, and also affected by symptoms related to poor circulation. Conclusions: In-depth data mining analysis identified relatively low importance questions and the potential to simplify OSD types.

• Korean Journal of Community Nutrition
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• v.29 no.4
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• pp.318-335
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• 2024

Objectives: Despite the growing market share of online grocery shopping, there is a need to understand customer perceived value due to the ongoing advancements in information technology. This study explores the connections between attributes, consequences, and values. Additionally, it conducts a cross-country comparison of consumers' online grocery shopping behaviors to gain a deeper understanding of consumer market segments and any potential variations among them. Methods: Data was collected through an online questionnaire survey conducted from May 1 to 15, 2024, targeting 400 consumers in Seoul, Korea, and Shanghai, China, who have experience with online grocery shopping. The survey utilized the Means-End Chain theory and association pattern technique hard laddering. Data collation and analysis were conducted using the IBM SPSS Statistics 28.0 program. The LadderUX software was employed to analyze the links between attributes, consequences, and values and create the consumer purchasing process's implication matrix and hierarchical value map (HVM). Results: The study identified key attributes that influence online grocery shopping decisions, including delivery service, price, freshness, and quality. Korean consumers demonstrated a higher sensitivity to price (19.0%) and delivery service (17.0%). In contrast, Chinese consumers prioritized delivery service (15.0%) and after-sales service (14.8%). Commonly cited consequences included time saving (12.6% for Koreans, 11.3% for Chinese), whereas prevalent values encompassed convenience (36.8% for Koreans, 19.6% for Chinese) and economic value (26.6% for Koreans, 14.7% for Chinese). The HVM underscored these insights, highlighting diverse consumer preferences and country-specific nuances. Conclusions: The findings highlight the current state of online food consumption and consumers' value systems, revealing variations among countries. These findings offer empirical insights that can be used to create customized global marketing strategies that resonate with various consumer preferences and market dynamics.