• 한국발생생물학회지:발생과생식
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• 제4권1호
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• pp.29-35
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• 2000

A phosphatidylinositol 3-kinase (PI3K)는 인슐린 신호전달의 상위구성 요소로 다양한 세포에서 단백질합성을 촉진한다. PI3K와 하위의 mammalian target of rapamycin (mTOR)가 착상전 생쥐 배아의 인슐린 신호전달에 관여하고 있는지의 여부를 조사하고자 하였다. 생쥐의 8-세포기 배아를 인슐린 또는 PI3K및 mTOR의 억제제를 포함한 조건에서 배양하면서 발생율, 할구수, 단백질합성 및 인산화를 조사하였다. 인슐린의 첨가는 포배형성과 부화 등 형태발생을 촉진하며 포배내 평균 할구수, 8-세포기 배아의 단백질 합성과 인산화를 유의하게 증가시켰다. PI3K의 억제제인 wortmannin과 mTOR를 억제하는 rapamycin은 인슐린에 의한 발생율, 포배내, 할구수, 단백질합성의 증가 효과를 상쇄하였다. 오토라디오그라피에서 두종의 인산화단백질인 pp22와 pp30의 인산화가 인슐린 처리에 의해 증가함을 확인하였다. 이상의 결과에서 생쥐 8-세포기 배아의 발생을 촉진하는 인슬린 신호의 전달에 PI3K와 mTOR가 관여함을 알 수 있다.

• Fisheries and Aquatic Sciences
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• 제11권1호
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• pp.7-14
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• 2008

The sanitary quality of a shellfish-growing area in Kamak Bay, Korea, was assessed through a bacteriological examination of seawater and oysters from January 2004 to December 2006. From seawater samples collected at 28 stations, the range of geometric mean (GM) and the estimated 90th percentile for most-probable-number (MPN) values of fecal coliforms were <1.8-2.4 MPN/100 mL and 1.8-6.0 MPN/100 mL, respectively. The observed fecal coliform GM and the estimated 90th percentile did not exceed the fecal coliform water quality standards of 14 MPN/100 mL and 43 MPN/100 mL. Therefore, the bacteriological quality of seawater at this shellfish-growing area met the Korean Shellfish Sanitation Program (KSSP) criteria for a growing area used for export. The range of the fecal coliform GM and the estimated 90th percentile MPN values of oyster samples were 19.2-160 MPN/100 g and 20.2-166.9 MPN/100 g, respectively, and the range of the viable cell count was 30-1900 CFU/g. Thus, the fecal coliform value for the oysters and the viable cell count were less than the current shellfish quality standards of 230 MPN/100 g and 50,000 CFU/g, respectively. The bacteriological quality of the oysters complied with the criteria for domestic use and export of shellfish.

• 대한골관절종양학회지
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• 제3권1호
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• pp.47-55
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• 1997

During the last decade, the use of primary amputation has decreased, and a larger number of patients are being treated with resection and reconstruction with limb preservation. The advantage of chemotherapy, improvements in diagnostic imaging methods and newer techniques for reconstruction have made limb salvage an alternative to amputation for most patients with malignant bone tumor. Clinical results and functional results of the limb salvage operation of bone tumors treated at the Department of Orthopaedic Surgery, Guro Hospital, Korea university was reviewed. Eighteen bone tumors(seven giant cell tumors and eleven malignant bone tumors.) were studied over a period of five years. The limb salvage group included fourteen endoprothesis, two pasteurized autograft, one near total scapulectomy and one rotationplasty. Functional evaluation was performed according to the Enneking's modified system. The results were as followed; 1. At a mean follow-up of thirty two months (15-77 months), fourteen(83%) of the eighteen patients with limb salvage procedures had been continuously disease free. 2. There are no local recurrence but deep infection developed in two patients and three patients with distant metastasis. 3. Thirteen(87%) of the fifteen patients showed above 60% of functional results. 4. Fourteen(93%) of the fifteen patients were satisfied with the limb salvage procedures.

• 대한수의학회지
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• 제39권3호
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• pp.635-644
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• 1999

The effect of isoprothiolane(di-isopropyl-1,3-dithiolan-2-ylidenemalonate) aganist fat necrosis in Hanwoo(Korean Cattle) sire was evaluated. The 10 heads of Hanwoo sire suffering from fat necrosis were given 50mg/kg body weight of isoprothiolane(0.2g/kg of Fujix, Japan) orally once a day for 8 weeks. In 30% of these, the size of the necrotic fat masses had decreased significantly 7 months after the adminstration. Isoprothiolane did not affect on live body weight and semen characteristics. However the sire affected with fat necrosis had higher MCHC(Mean corpuscular hemoglobin concentration) than normal sire in hematologic values 10 weeks after administration. Number of RBC(red blood cell) and PCV(packed cell volume) 10 weeks after administration had been increased than those before administration(p < 0.05). The serum concentrations of creatinine, triglyceride, and total cholesterol 10 weeks after administration were higher than those before administration while the concentration of glucose was vice versa. The isoprothiolane may reduce the oxidation of glucose, increase the glucose transfer to lipids, and increase blood supply to necrotic masses. These results indicate that isoprothiolane may be useful as the therapeutic agent aganist fat necrosis.

• 한국통신학회논문지
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• 제25권9A호
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• pp.1332-1339
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• 2000

본 논문에서는 MCNS(Multimedia Cable N$\xi$twork System)의 DOCSIS(Data Over Cable Service Interface S Specification) 표준안의 물리계층을 지원하는 비대칭형 기저대역 모댐 ASIC 칩의 아키텍쳐와 설계에 대해 기술한다. 구현한 모뎀 칩은 크게 QPSK/16-QAM 방식의 상향 스트림용 송신부와 64/256-QAM 방식의 하향 스트림용 수신부로 구성되어 있으며, 심볼 타이밍 복구회로, 반송파 복구회로. MMA(Multi Modulus Algorithm)와 LMS(Least Mean Square) 알고리즘을 적용한 결정 궤환 구조의 블라인드 등화기를 포함한다. 구현한 모뎀 칩은 64/256-QAM 변복조 방식에서 각각 48Mbps, 64Mbps의 데이터 전송률을 지원하고, 심볼 전송률은 기존의 QAM 수신기들보다 빠른 8MBaud를 갖는다. 구현한 칩은 $0.35\mu\textrm{m}$ 표준 셀(Standard Cell) 라이브러리를 사용하여 논리합성을 수행하였으며, 총 게이트 수는 약 29만 게이트이며, 현재 ASIC 칩으후 제작중이다.

• Nuclear Engineering and Technology
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• 제54권6호
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• pp.2276-2296
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• 2022

This study validates the applicability of the CUPID code for simulating subcooled wall boiling under high-pressure conditions against number of DEBORA tests. In addition, a new numerical technique in which the interfacial momentum non-drag forces are calculated at the cell faces rather than the center is presented. This method reduced the numerical instability often triggered by calculating these terms at the cell center. Simulation results showed good agreement against the experimental data except for the bubble sizes in the bulk. Thus, a new model to calculate the Sauter mean diameter is proposed. Next, the effect of the relationship between the bubble departure diameter (D_dep) and the nucleation site density (N) on the performance of the Wall Heat Flux Partitioning (WHFP) model is investigated. Three correlations for D_dep and two for N are grouped into six combinations. Results by the different combinations show that despite the significant difference in the calculated D_dep, most combinations reasonably predict vapor distribution and liquid temperature. Analysis of the axial propagations of wall boiling parameters shows that the N term stabilizes the inconsistences in D_dep values by following a behavior reflective of D_dep to keep the total energy balance. Moreover, ratio of the heat flux components vary widely along the flow depending on the combinations. These results suggest that separate validation of D_dep correlations may be insufficient since its performance relies on the accompanying N correlations.

• 한국수산과학회지
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• 제27권1호
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• pp.69-82
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• 1994

해조류를 첨가한 사료가 조피볼락의 어린 시기에 미치는 생리적 효과를 알아보기 위하여, 전장 $2.99{\pm}0.23\;cm$, 체중 $1.03{\pm}0.18\;g$의 인공종묘에게 미역분말을 각각 $3\%,\;5\%,\;7\%$ 첨가한 사료와 비첨가 사료를 주면서 140일간 사육하여 전장$18.52{\pm}1.07\;cm$, 체중 $120.64{\pm}19.32\;g$이 될 때까지의 어체 성장, 생존율, 체조성, 혈액조성을 서로 비교하고, 저산소 및 기아 내성에 관한 생리활성을 연구하였다. 1. 전장과 체중의 성장은 $5\%$의 미역 첨가시 가장 좋았으며, $3\%,\;7\%$, 대조구인 $0\%$ 순이었다. 2. 실험구별 사료효율은 $3\%,\;5\%,\;7\%,\;0\%$구의 순으로 높았으며, 생존율은 $7\%,\;5\%,\;3\%,\;0\%$구 순이었다. 3. 사육종료시의 체조성에 있어 등 근육의 수분, 조단백질, 조지방 및 조회분은 실험구별로 큰 차이를 보이지 않았으나, 전내장의 조지방 함량은 미역 첨가구가 대조구에 비해 많았다. 4. 미역 첨가구는 $0\%$구 보다 헤마토크릿트값이 크고, 평균적혈구수도 많았다. 5. 실험종료시 사료별 어체의 저산소내성은 미역 첨가구가 대조구에 비해 강했다. 6. 사육실험 종료후 31일간의 기아 실험에서 미역 첨가구의 어체중은 대조구에 비해 적게 감소하였다. 7. 조피볼락 양식에서 사료에 미역을 첨가해 줄 경우, 그 비율은 $5\%$가 가장 적합하며 어체의 생리조건에 좋은 영향을 줄 수 있는 것으로 판단되었다.

• Journal of Nutrition and Health
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• 제15권3호
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• pp.171-180
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• 1982

The nutritional survey and blood sampling was conducted from May 23 to 27, 1971, in order to investigate the state of the nutritional intake in relation to blood contents of rural women. This survey covered a total of 47 women residing in Youngam-gun, Cholla-namdo, Korea. The daily diet of these subjects was observed by 24-hour recall method and weighing method for 3 days and hemoglobin (Hb), hematocrit(Hct), mean corpuscular hemoglobin concentration (MCHC), serum protein, serum albumin, A/G ratio, serum iron, total iron binding capacity (TIBC), transferrin saturation (TS), serum cholesterol and blood specific gravity (SG) were measured. The results were summarized as follows ; The rate of intake of vegetable foods was high, especially cereals, and that of animal foods was low, especially eggs and milk and milk products. The daily intake of niacin was sufficient, and the intakes of energy and iron were also tend to be adequate. On the contrary, the intakes of vitamin A, $B_2$ and C, calcium and protein were insufficient. The mean red blood cell number was $410.8{\pm}26.4{\times}10^{4}/mm^{3},$ the mean values of Hb, Hct and MCHC were $12.5{\pm}0.9gm%$, $37.5{\pm}2.4%$ and $33.2{\pm}0.5%$ thus the anemic prevalences were 21.3%, 12.8% and 93.6% comparing with the anemic criteria of WHO. The levels of serum protein and serum albumin were $7.1{\pm}0.4gm\;%$ and $4.3{\pm}0.3gm\;%$so the A/G ratio was indicated $1.6{\pm}0.2.$. The levels of serum iron and TIBC were $91.9{\pm}27.5{\mu}g/100ml and $297.5{\pm}31.4{\mu}g/100ml,$ so TS was calculated $31.2{\pm}9.7\;%$. The mean value of SG was $1.044{\pm}0.002,$ and the level of serum cholesterol was $164.3{\pm}25.4mg/dl$. In the relation between each of bloood content, Hb showed positive correlation not only with Hct but also protein at the level of significance of 1 per cent and 5 per cent, and protein also showed a positive correlation with serum cholesterol at the 1 per cent level of significance. In the relation between the nutrient intake and blood contents, vitamin C intake showed a positive correlation with Hb, serum protein and serum iron at the level of significance of 1 per cent, iron intake also showed a positive correlation with serum iron and serum cholesterol at the same significant level, and protein intake showed a positive correlation with serum iron at the at the level of significance of 5 per cent.

• 한국항해항만학회지
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• 제27권3호
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• pp.283-288
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• 2003

Recently, the growth of applications and services over high-speed Internet increases, ATM networks as wide area back-bone has been a major solution. As the conventional TCP/IP suite is still the standard protocol used to support upper application on current. Internet, the issues regarding whether TCP/IP will operate efficiently on top of an ATM infrastructure and how to control its QoS still remain for studies. TCP uses a window-based protocol for flow control in the transport layer. When TCP uses the UBR service in ATM layer, the control method is only buffer management. If a cell is discarded in ATM layer, one whole packet of TCP will be lost; this fact occur the most TCP performance degradation. Several dropping strategies, such as Tail Drop, EPD, PPD, SPD, FBA, have been proposed to improve the TCP performance over ATM. In this paper, to improve the TCP performance, we propose a packet dropping scheme that is based on comparison with EPD, SPD and FBA. Our proposed scheme is applied to schemes discussed in the previous technology. Our proposed scheme does not need to know each connection's mean packet size. When the buffer exceeds the given threshold, it is based on comparison between the number of dropped packet and the approved packet. Our results are reported and discussed for comparing these discarding schemes under similar conditions. Although the number of virtual channel (VC) is increased, the simulation results showed that the proposed scheme can allocate more fairly each VC than other scheme.

• 에너지공학
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• 제20권1호
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• pp.44-53
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• 2011

본 논문에서는 마주보는 두 벽면들이 서로 다른 온도로 유지되는 2차원 사각형 공간 내 공기의 층류 자연대류를 수치해석 방법을 사용하여 $10^6$의 Rayleigh 수까지 조사하였다. 사각공간의 폭과 높이의 비가 1, 2, 4인 경우와 $0^{\circ}{\leq}{\theta}{\leq}90^{\circ}$의 경사각도 범위에서 계산을 수행하였다. $10^3{\leq}Ra{\leq}10^6$의 범위에서 공간의 경사각도가 유동 구조와 열전달에 미치는 영향을 각 종횡비에 대하여 조사하였다. 작은 종횡비의 경우에는 공간 구석에서 발달되는 2차 유동 셀들이 총괄 열전달의 감소를 초래하는 것으로 나타났으며, 큰 종횡비의 경우에는 3개의 유동 셀이 1개로 전이되는 과정에서 스텝모양과 비슷한 열전달의 급 감소가 일어났다. 수직의 경우인 ${\theta}=90^{\circ}$에 대해서 새로운 평균 Nusselt 수 상관식이 제공되었다.