• Title/Summary/Keyword: Mean Reduction Method

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A Simple Calculational Method by using Modified Von Mises Transformation applied to the Coaxial Turbulent Jet Mixing (유동함수를 이용한 난류제트혼합유동 계산에 관한 연구)

  • Choi Dong-Whan
    • Journal of the Korean Society of Propulsion Engineers
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    • v.9 no.2
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    • pp.97-104
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    • 2005
  • A simple but efficient grid generation technique by using the modified compressible form of stream function has been formulated. Transformation of a physical plane to a streamline plane, the Von Mises Transformation, has been widely used to solve the differential equations governing flow phenomena, however, limitation arises in low velocity region of boundary layer, mixing layer and wake region where the relatively large grid spacing is inevitable. Modified Von Mises Transformation with simple mathematical adjustment for the stream function is suggested and applied to solve the confined coaxial turbulent jet mixing with simple $\kappa-\epsilon$ turbulence model. Comparison with several experimental data of axial mean velocity, turbulent kinetic energy, and Reynolds shear stress distribution shows quite good agreement in the mixing layer except in the centerline where the turbulent kinetic energy distributions were somewhat under estimated. This formulation is strongly suggested to be utilized specially for free turbulent mixing layers in axisymmetric flow conditions such as the investigation of mixing behavior, jet noise production and reduction for Turbofan engines.

Computational predictions of improved of wall mechanics and function of the infarcted left ventricle at early and late remodelling stages: comparison of layered and bulk hydrogel injectates

  • Kortsmit, Jeroen;Davies, Neil H.;Miller, Renee;Zilla, Peter;Franz, Thomas
    • Advances in biomechanics and applications
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    • v.1 no.1
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    • pp.41-55
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    • 2014
  • Acellular intra-myocardial biomaterial injections have been shown to be therapeutically beneficial in inhibiting ventricular remodelling of myocardial infarction (MI). Based on a biventricular canine cardiac geometry, various finite element models were developed that comprised an ischemic (II) or scarred infarct (SDI) in left ventricular (LV) antero-apical region, without and with intra-myocardial biomaterial injectate in layered (L) and bulk (B) distribution. Changes in myocardial properties and LV geometry were implemented corresponding to infarct stage (tissue softening vs. stiffening, infarct thinning, and cavity dilation) and injectate (infarct thickening). The layered and bulk injectate increased ejection fraction of the infarcted LV by 77% (II+L) and 25% (II+B) at the ischemic stage and by 61% (SDI+L) and 63% (SDI+B) at the remodelling stage. The injectates decreased the mean end-systolic myofibre stress in the infarct by 99% (II+L), 97% (II+B), 70% (SDI+L) and 36% (SDI+B). The bulk injectate was slightly more effective in improving LV function at the remodelling stage whereas the layered injectate was superior in functional improvement at ischemic stage and in reduction of wall stress at ischemic and remodelling stage. These findings may stimulate and guide further research towards tailoring acellular biomaterial injectate therapies for MI.

Functional Outcomes of Subaxial Spine Injuries Managed With 2-Level Anterior Cervical Corpectomy and Fusion: A Prospective Study

  • Jain, Vaibhav;Madan, Ankit;Thakur, Manoj;Thakur, Amit
    • Neurospine
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    • v.15 no.4
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    • pp.368-375
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    • 2018
  • Objective: To evaluate the results of operative management of subaxial spine injuries managed with 2-level anterior cervical corpectomy and fusion with a cervical locking plate and autologous bone-filled titanium mesh cage. Methods: This study included 23 patients with a subaxial spine injury who matched the inclusion criteria, underwent 2-level anterior cervical corpectomy and fusion at our institution between 2013 and 2016, and were followed up for neurological recovery, axial pain, fusion, pseudarthrosis, and implant failure. Results: According to Allen and Ferguson classification, there were 9 cases of distractive extension; 4 of compressive extension; 3 each of compressive flexion, vertical compression, and distractive flexion; and 1 of lateral flexion. Sixteen patients had a score of 6 on the Subaxial Injury Classification system, and the rest had a score of more than 6. The mean follow-up period was 19 months (range, 12-48 months). Neurological recovery was observed in most of the patients (78.21%). All patients experienced relief of axial pain. None of the patients received a blood transfusion. Twenty-one patients (91.3%) showed solid fusion and 2 (8.69%) showed possible pseudarthrosis, with no complications related to the cage or plate. Conclusion: Two-level anterior cervical corpectomy and fusion, along with stabilization with a cervical locking plate and autologous bone graft-filled titanium mesh cage, can be considered a feasible and safe method for treating specific subaxial spine injuries, with the benefits of high primary stability, anatomical reduction, and direct decompression of the spinal cord.

Types of Hazardous Factors and Time-trend of Exposure Levels from the Working Environment at a Shock Absorber Manufacturing Facility (자동차 쇼크업소바 제조사업장의 작업자 노출 유해인자의 종류 및 노출수준의 경시적 변화)

  • Na, Gyu-Chae;Moon, Chan-Seok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.28 no.4
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    • pp.393-405
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    • 2018
  • Objective: This study examines the types of hazardous factors in the working environment and the time-trend for their exposure levels over 10 years (2007 to 2016). Study Design and Method: The types of hazardous factors and exposure levels were drawn from the 19 measurement reports on the working environment over 10 years at a shock absorber manufacturing facility. Risk assessment of the types of factors and time-trend of exposure levels were evaluated using the factors and exposure levels. Results: A total of 34 hazardous factors were evaluated. The types were noise, 15 organic compounds, seven kinds of acid sand alkalis, eight kinds of heavy metals, and three other compounds. Special management materials used were nickel, hexavalent chrome, and sulfuric acid. Human carcinogens (1A) used were trichloroethylene, nickel, and sulfuric acid. There were six types of substances belonging to the IARC's 2B (body carcinogens) classification or higher, including, methyl isobutyl ketone, ethyl benzene, and trichloroethylene. No detection was found for 627 out of the 2065 total measurements in 19 exposure survey reports, representing 30.4%. Organic solvents, acid and alkali products, and heavy metals showed continuous low exposure concentrations. Noise, welding fumes, and the evaluation of mixed solvents show a gradual decrease in geometric mean and maximum over the time-trend of 10 years. Conclusions: In the case of a shock absorber manufacturing facility, the hazardous factors of noise and the evaluation of mixed solvents still indicate high concentrations exceeding the exposure limits and necessitate reduction studies. These two factors and welding fumes showed a continuous decrease in their ten-year tendency. Organic compounds, acids/alkalis, and heavy metals were managed smoothly in a work environment of continuous low concentrations.

The Risk Factors Associated with Nonunion after Surgical Treatment for Distal Fibular Fractures (원위 비골 골절의 수술 후 발생한 불유합의 관련 인자)

  • Lee, Jun Young;Choi, Kwi Youn;Kang, Sinwook;Ko, Kang Yeol
    • Journal of Korean Foot and Ankle Society
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    • v.22 no.3
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    • pp.95-99
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    • 2018
  • Purpose: The purpose of this study was to evaluate the radiologic outcomes of distal fibular fractures and to analyze the risk factors associated with nonunion. Materials and Methods: Between January 2009 and March 2016, 13 patients who had final nonunion with ankle fracture were included. In the control group, 370 patients who had undergone bony union and removed metal implants were included. All patients underwent the same surgical procedure and had the same treatment method, ultimately achieving satisfactory open reduction results with less than 2 mm fracture gap. Surgical treatment of fracture was considered to have the same effect on nonunion, and factors that might be associated with nonunion were evaluated. SPSS ver. 13.0 (SPSS Inc., USA) was used for all statistical analyses. Pearson's chi-square test and multi-variate regression analysis were performed to determine the factors affecting nonunion of distal fibular fracture. A p-value less than 0.05 was considered statistically significant, and relative risk was assessed. Results: The mean age of 13 patients was 46.9 years (range, 16~57 years); there were 8 men and 5 women. Among the 13 patients with nonunion, atrophic was the most common (12 cases). The association between the injury mechanism and the Lauge-Hansen classification and diabetes mellitus was not statistically significant. Distal fibular fractures with tibia shaft fracture (p=0.015) and Danis-Weber type C fracture (p=0.023), open fracture (p=0.011), and smoking (p=0.023) were significantly associated with nonunion. Conclusion: In this study, the combined injury of the ipsilateral tibia shaft fracture, open fracture, and Danis-Weber type C fracture may increase the possibility of nonunion. Therefore, caution is advised to prevent nonunion.

Effects of different wind deflectors on wind loads for extra-large cooling towers

  • Ke, S.T.;Zhu, P.;Ge, Y.J.
    • Wind and Structures
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    • v.28 no.5
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    • pp.299-313
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    • 2019
  • In order to examine the effects of different wind deflectors on the wind load distribution characteristics of extra-large cooling towers, a comparative study of the distribution characteristics of wind pressures on the surface of three large cooling towers with typical wind deflectors and one tower without wind deflector was conducted using wind tunnel tests. These characteristics include aerodynamic parameters such as mean wind pressures, fluctuating wind pressures, peak factors, correlation coefficients, extreme wind pressures, drag coefficients and vorticity distribution. Then distribution regularities of different wind deflectors on global and local wind pressure of extra-large cooling towers was extracted, and finally the fitting formula of extreme wind pressure of the cooling towers with different wind deflectors was provided. The results showed that the large eddy simulation (LES) method used in this article could be used to accurately simulate wind loads of such extra-large cooling towers. The three typical wind deflectors could effectively reduce the average wind pressure of the negative pressure extreme regions in the central part of the tower, and were also effective in reducing the root of the variance of the fluctuating wind pressure in the upper-middle part of the windward side of the tower, with the curved air deflector showing particularly. All the different wind deflectors effectively reduced the wind pressure extremes of the middle and lower regions of the windward side of the tower and of the negative pressure extremes region, with the best effect occurring in the curved wind deflector. After the wind deflectors were installed the drag coefficient values of each layer of the middle and lower parts of the tower were significantly higher than that without wind deflector, but the effect on the drag coefficients of layers above the throat was weak. The peak factors for the windward side, the side and leeward side of the extra-large cooling towers with different wind deflectors were set as 3.29, 3.41 and 3.50, respectively.

Genotype by environment interaction for somatic cell score in Holstein cattle of southern Brazil via reaction norms

  • Mulim, Henrique Alberto;Pinto, Luis Fernando Batista;Valloto, Altair Antonio;Pedrosa, Victor Breno
    • Animal Bioscience
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    • v.34 no.4
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    • pp.499-505
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    • 2021
  • Objective: The objective of this study was to evaluate the genetic behavior of a population of Holstein cattle in response to the variation of environmental temperature by analyzing the effects of genotype by environment interaction (GEI) through reaction norms for the somatic cell score (SCS). Methods: Data was collected for 67,206 primiparous cows from the database of the Paraná Holstein Breeders Association in Brazil, with the aim of evaluating the temperature effect, considered as an environmental variable, distinguished under six gradients, with the variation range found being 17℃ to 19.5℃, over the region. A reaction norm model was adopted utilizing the fourth order under the Legendre polynomials, using the mixed models of analysis by the restricted maximum likelihood method by the WOMBAT software. Additionally, the genetic behavior of the 15 most representative bulls was assessed, in response to the changes in the temperature gradient. Results: A mean score of 2.66 and a heritability variation from 0.17 to 0.23 was found in the regional temperature increase. The correlation between the environmental gradients proved to be higher than 0.80. Distinctive genetic behaviors were observed according to the increase in regional temperature, with an observed increase of up to 0.258 in the breeding values of some animals, as well as a reduction in the breeding of up to 0.793, with occasional reclassifications being observed as the temperature increased. Conclusion: Non-relevant GEI for SCS were observed in Holstein cattle herds of southern Brazil. Thus, the inclusion of the temperature effect in the model of genetic evaluation of SCS for the southern Brazilian Holstein breed is not required.

Optimizing Hydrological Quantitative Precipitation Forecast (HQPF) based on Machine Learning for Rainfall Impact Forecasting (호우 영향예보를 위한 머신러닝 기반의 수문학적 정량강우예측(HQPF) 최적화 방안)

  • Lee, Han-Su;Jee, Yongkeun;Lee, Young-Mi;Kim, Byung-Sik
    • Journal of Environmental Science International
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    • v.30 no.12
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    • pp.1053-1065
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    • 2021
  • In this study, the prediction technology of Hydrological Quantitative Precipitation Forecast (HQPF) was improved by optimizing the weather predictors used as input data for machine learning. Results comparison was conducted using bias and Root Mean Square Error (RMSE), which are predictive accuracy verification indicators, based on the heavy rain case on August 21, 2021. By comparing the rainfall simulated using the improved HQPF and the observed accumulated rainfall, it was revealed that all HQPFs (conventional HQPF and improved HQPF 1 and HQPF 2) showed a decrease in rainfall as the lead time increased for the entire grid region. Hence, the difference from the observed rainfall increased. In the accumulated rainfall evaluation due to the reduction of input factors, compared to the existing HQPF, improved HQPF 1 and 2 predicted a larger accumulated rainfall. Furthermore, HQPF 2 used the lowest number of input factors and simulated more accumulated rainfall than that projected by conventional HQPF and HQPF 1. By improving the performance of conventional machine learning despite using lesser variables, the preprocessing period and model execution time can be reduced, thereby contributing to model optimization. As an additional advanced method of HQPF 1 and 2 mentioned above, a simulated analysis of the Local ENsemble prediction System (LENS) ensemble member and low pressure, one of the observed meteorological factors, was analyzed. Based on the results of this study, if we select for the positively performing ensemble members based on the heavy rain characteristics of Korea or apply additional weights differently for each ensemble member, the prediction accuracy is expected to increase.

Comparison of Clinical Outcomes between Rebound Hyperthermia and Non-Rebound Hypertherma Groups in Postcardiac Arrest Syndrome Patients Undergoing Targeted Temperature Management (목표체온유지치료를 적용한 심정지 후 증후군 환자에서 반동성 고체온 발생군과 비발생군의 임상결과 비교)

  • Rhee, Ha Na;Park, Jeong Yun
    • Journal of Korean Critical Care Nursing
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    • v.16 no.3
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    • pp.99-108
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    • 2023
  • Purpose : This retrospective study aims to provide basic data for intervention to improve clinical outcomes and identify the characteristics of the rebound hyperthermia (RHG) and non-rebound hyperthermia (NRHG) groups by checking body temperature in patients with post-cardiac arrest syndrome. Method : The study involved 118 patients who completed target temperature management (TTM) in an acute-care unit. Data were analyzed for frequency, percentages, mean, standard deviation, median, and quartiles, and compared using the chi-squared test and Mann-Whitney U-test. Results : Rebound hyperthermia (RH) was observed in 74 (62.7%) patients, predominantly male (69.5%), with an average age of 64.54 ± 15.98, and a body mass index of 23.22 ± 4.75kg/m2 (overweight). Hypertension (50%) was the most common co-morbidity, followed by diabetes and heart disease (33.1%). Neuron-specific enolase levels were higher in the NRHG 24, 48, and 72 hours after recovery of spontaneous circulation (p = .037, p < .001, p = .008). The APHCHE IV was also higher in the NRHG (p < .001). RH occurred 25.49 (7.28-52.96) hours after TTM completion, lasting for 2 (1-3) hours. Temperature reduction strategies included notifying doctors, administering antipyretics, and nursing intervention, with the latter being the most common at 94.6%. Half of the subjects in the RHG and 77.3% in the NRHG fell into cerebral performance categories 3, 4, and 5 (p = .003). Conclusion : RH is more likely a body mechanism related to CPR and TTM than a result of pathogenic infection. Therefore, we require an active intervention for hyperthermia, and a patient-specific nursing intervention protocol.

Comparison of the Therapeutic Efficacy and Technical Outcomes between Conventional Fixed Electrodes and Adjustable Electrodes in the Radiofrequency Ablation of Benign Thyroid Nodules

  • Jae Ho Shin;Minkook Seo;Min Kyoung Lee;So Lyung Jung
    • Korean Journal of Radiology
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    • v.25 no.2
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    • pp.199-209
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    • 2024
  • Objective: This study aimed to compare therapeutic efficacy and technical outcomes between adjustable electrode (AE) and conventional fixed electrode (FE) for radiofrequency ablation (RFA) of benign thyroid nodules. Materials and Methods: Between 2013 and 2021, RFA was performed on histologically proven benign thyroid nodules. For the AE method, AE length ≥ 1 cm with higher power and < 1 cm with lower power were utilized for ablating feeding vessels and nodules, especially those near anatomical structures, respectively. The therapeutic efficacy (volume reduction rate [VRR], complication rate, and regrowth rate) and technical outcomes (total energy delivery, ablated volume/energy, RFA time, and ablated volume/time) of FE and AE were compared. Continuous parameters were compared using a two-sample t-test or Mann-Whitney U test, and categorical parameters were compared using a chi-squared test or Fisher's exact test. Results: A total of 182 nodules (FE: 92 vs. AE: 90) in 173 patients (mean age ± standard deviation, 47.0 ± 14.7 years; female, 90.8% [157/173]; median follow-up, 726 days [interquartile range, 441-1075 days]) were analyzed. The therapeutic efficacy was comparable, whereas technical outcomes were more favorable for AE. Both electrodes demonstrated comparable overall median VRR (FE: 92.4% vs. AE: 84.9%, P = 0.240) without immediate major complications. Overall regrowth rates were comparable between the two groups (FE: 2.2% [2/90] vs. AE: 1.1% [1/90], P > 0.99). AE demonstrated a shorter median RFA time (FE: 811 vs. AE: 627 seconds, P = 0.009). Both delivered comparable median energy (FE: 42.8 vs. AE: 29.2 kJ, P = 0.069), but AE demonstrated higher median ablated volume/energy and median ablated volume/time (FE: 0.2 vs. AE: 0.3 cc/kJ, P < 0.001; and FE: 0.7 vs. AE: 1.0 cc/min, P < 0.001, respectively). Conclusion: Therapeutic efficacy between FE and AE was comparable. AE demonstrated better technical outcomes than FE in terms of RFA time, ablated volume/energy, and ablated volume/time.