• Korean Journal of Clinical Pharmacy
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• v.20 no.1
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• pp.66-71
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• 2010

주의력결핍 과잉행동장애는 미국에서 약 200만 명의 어린이에게 나타나는 심각한 만성 신경행동학적 장애이다. 주의력결핍 과잉행동장애 치료의 중심은 약물요법이다. 그러나 현재 환자의 약 30%는 주의력결핍 과잉행동장애를 적응증으로 갖도록 허가된 의약품들을 사용해도 적절한 치료효과를 얻지 못하고 있는 상황이다. Modafinil은 methylphenidate나 amphetamines와 같은 각성제와는 다른 약리학적 기전으로 중추신경계를 항진시킨다. 본 연구는 modafinil의 주의력결핍 과잉행동장애 치료효과에 대한 최신 지견을 얻고자, 1990년부터 2010년 3월까지 MEDLINE에 등재된 논문을 ADHD와 Modafinil이라는 MeSH terms로 검색하여 추출한 자료 중에서 대조군이 사용된 무작위 배정 및 이중맹검 임상연구 사례만을 선별하여 임상적 유용성을 평가하였다. 현재 modafinil은 주의력결핍 과잉행동 장애 치료제로 허가된 의약품은 아니지만 최근 여러 국가에서 시행된 연구들은 modafinil이 안전하고 효과적인 주의력결핍 과잉행동장애 치료제일 수 있다는 결과를 보여주고 있다.

• Perspectives in Nursing Science
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• v.1 no.1
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• pp.85-102
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• 2004

Purpose: The purpose of this study was to identify the trend of nursing research by analyzing doctoral dissertations of nursing college at Seoul National University. Method: The doctoral dissertations used in this study were 69 thesis from 1989 to 2001. The methodological characteristics, theory, philosophy and world view in these thesis were explored. Key words were classified according to metaparadigm and were compared with MeSH term. Result: There were 54 dissertations of quantitative research and 12 dissertations of qualitative research. Most of subjects of the thesis were patients with 20~65 years old. The written consent to participate in research was not described in great part of thesis. As to measurement, questionnaire was most frequent used. In independent variables cognitive nursing interventions were used frequently. Psychosocial variables as a dependent variable were used mainly. In theory level of research, situation-producing research was performed. In type of nursing knowledge according to Caper many dissertations studied about empirical knowledge. More than half of doctoral dissertations used borrowed theory from nursing related disciplines. Most of studies were done within empirical positivism and organic viewpoint. Key words related to the concept of environment among four metaparadigm has been insufficiently studied. English key words in doctoral thesis were out of accordance largely with MeSH term English. Conclusion: These results show that it is necessary to develop the nursing theory for nursing knowledge body.

• Research in Community and Public Health Nursing
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• v.29 no.4
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• pp.429-439
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• 2018

Purpose: The aim of this study is to identify core keyword of frailty research in the past 35 years to understand the structure of knowledge of frailty. Methods: 10,367 frailty articles published between 1981 and April 2016 were retrieved from Web of Science. Keywords from these articles were extracted using Bibexcel and social network analysis was conducted with the occurrence network using NetMiner program. Results: The top five keywords with a high frequency of occurrence include 'disability', 'nursing home', 'sarcopenia', 'exercise', and 'dementia'. Keywords were classified by subheadings of MeSH and the majority of them were included under the healthcare and physical dimensions. The degree centralities of the keywords were arranged in the order of 'long term care' (0.55), 'gait' (0.42), 'physical activity' (0.42), 'quality of life' (0.42), and 'physical performance' (0.38). The betweenness centralities of the keywords were listed in the order of depression' (0.32), 'quality of life' (0.28), 'home care' (0.28), 'geriatric assessment' (0.28), and 'fall' (0.27). The cluster analysis shows that the frailty research field is divided into seven clusters: aging, sarcopenia, inflammation, mortality, frailty index, older people, and physical activity. Conclusion: After reviewing previous research in the 35 years, it has been found that only physical frailty and frailty related to medicine have been emphasized. Further research in psychological, cognitive, social, and environmental frailty is needed to understand frailty in a multifaceted and integrative manner.

• International Journal of Advanced Culture Technology
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• v.9 no.2
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• pp.47-55
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• 2021

The coronavirus disease 2019 (COVID-19) pandemic continuously influences on the health and well-being of people and communities worldwide. The purpose of this study was to explore the published research articles in the fields of nursing and health during the COVID-19 pandemic. The research design is an exploratory study. Samples are the abstracts of the articles from a literature database, PubMed, that were published from January 1st, 2020 to April 15th, 2021. We used a MeSH term, 'nursing' and "COVID-19" to retrieve articles that are related to COVID-19. Five hundred and fifty-five articles were retrieved. Two hundred and sixteen articles were excluded as they were not met the inclusion criteria. The total number of articles used in this study was three hundred and thirty-nine. The average number of articles published during the data collection period was 21.9. Seven topics were discovered from the abstracts of the articles: COVID-19 management and guidance; Perinatal COVID-19 and breastfeeding; Nurse; Health service and support; Patient care; Research; and Education and experience. This study revealed some interesting topics from the articles related to COVID-19 and provided some sense of research areas that may be interesting and allow us to develop important research questions about nursing science and nursing practice.

• Journal of Korean Medical classics
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• v.22 no.1
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• pp.191-205
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• 2009

Objective : Up to the present, theories of medical books is too difficult to understand thoroughly. However, these study methods have some problems in dealing with lots of meaning because the comprehension of theories are dependent upon one's memory. Especially, comparison distinct medical books are more difficult matter. So, we have attempted to solve a problem. Method : We have researched medical terms in the "Piweilun" according to below the procedure. (1) Making a terms list: We have selected constituent of sentence. And we have made term list on the basis of concept of term. (2) Making a synonym list: We have collected identical conception and made a synonym list. So, using an synonym tables of DB, it is possible to search for the non-standard terms of medical theory. (3) Making a classification system: Using UMLS(Unified Medical Language System), MeSH(Medical Subject Headings), IST(International Standard Terminology) ect., we have made a classification system of oriental medicine terms in the "Piwelun". Analysis of relation between terms. Result : In the "Piweilun", there are more than 1,790s concepts. Parts of those are belonged to UMLS-Semantic Type, the other parts of those are not belonged to UMLS-Semantic Type. And those include predicate more than UMLS-Semantic Relations.

• Korean Journal of Clinical Pharmacy
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• v.20 no.2
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• pp.138-144
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• 2010

The results from eight randomized controlled studies demonstrate that venlafaxine is effective in the treatment of hot flashes with tolerable adverse effects. Based on the results of the above studies, venlafaxine can be recommended for the treatment of hot flashes. However, there are limitations in the above studies. The inclusion criteria of 5 studies reviewed in this paper was breast cancer patients, so it's hard to apply the results to the general population in clinical practice. Also 5 studies had less than 100 subjects included, and 18-week study was the longest one among studies reviewed in this paper. Therefore, large and long-term clinical studies with the general population should be conducted to use venlafaxine for the treatment of hot flashes in clinical practice.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.5171-5176
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• 2012

We here performed a systematic review of PBIC literature using terms analysis in a hope of both identifying potential trends and patterns and exploring methods leveraging traditional literature reviews in this specific area. Articles meeting inclusion criteria were retrieved from PUBMED and translated into dichotomized article records representing presence or non-presence of MeSH terms and a metric consisting of numbers of times of co-occurrence between all pairs of terms identified using a self-designed program. The occurrence of and relations among the terms were calculated and visualized using Excel2007 and UCINET respectively. A total of 1,742 terms were identified from 997 articles retrieved. Put in a descending order, the lines representing the times of term occurrence formed a typical hyperbolic curve; when plotted along the x-axis of whole MESH terms, the lines clustered within four specific regions. Comparison of term occurrence between 2002 and 2011 revealed priority changes in population and subjects (from general groups to priority groups), intervention approaches (from medicine to exercise and psychotherapy), methodology and techniques (from cohort studies to randomized controlled trials) and outcomes (from health and mental health to quality of life, depression etc.). Networks of the terms featured a number of closely linked groups of topics including method and questionnaires, therapy and outcomes, survival management, psychological assessment and intervention, behavioral intervention (individual and community oriented). Terms analysis revealed interesting trends and patterns about PBIC publications and both the analysis methods and findings have implications for future research and literature reviews.

• Korean Journal of Clinical Pharmacy
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• v.21 no.4
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• pp.376-382
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• 2011

The results from eight clinical studies demonstrate that citalopram and escitalopram could be an effective option in the treatment of hot flashes with tolerable adverse effects. However, there are limitations in the above studies. The inclusion criteria of 2 studies reviewed in this paper was breast cancer patients, so it's hard to apply the results to the general population in clinical practice. Also 4 studies had less than 50 subjects included, and the duration of study was 8 weeks or less in 7 studies reviewed in this paper. Moreover, only 4 studies were randomized, placebo-controlled trials (3 for citalopram and 1 for escitalopram). Therefore, further randomized, double-blind, placebo-controlled studies with the general population should be needed to use citalopram and escitalopram for the treatment of hot flashes in clinical practice.

• Journal of Practical Engineering Education
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• v.15 no.2
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• pp.495-502
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• 2023

Despite the fact that Korea has supported national cancer screening worldwide for a long time, the cancer screening screening rate is low compared to other health screenings and infant screening. In particular, women with disabilities show a lower screening rate for cervical cancer screening compared to women without disabilities. Therefore, from 2011 to 2019, this study investigated the trends in cervical cancer screening rates of women with disabilities and non-disabled women aged 30 and older, and analyzed the factors affecting cervical cancer screening of women with disabilities at the individual and regional level through the cervical cancer screening rates among regions. The purpose of this study is to identify the factors that affect regional variation by dividing into regions. From 2011~2019, the cervical cancer screening rate of people with disabilities was the highest in Daejeon and the lowest in Sejong and Jeju, and the gap in cervical cancer screening rate of people with disabilities by region was analyzed to be up to 13.1%.