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Breast Radiotherapy with Mixed Energy Photons; a Model for Optimal Beam Weighting

  • Birgani, Mohammadjavad Tahmasebi;Fatahiasl, Jafar;Hosseini, Seyed Mohammad;Bagheri, Ali;Behrooz, Mohammad Ali;Zabiehzadeh, Mansour;meskani, Reza;Gomari, Maryam Talaei
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.17
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    • pp.7785-7788
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    • 2015
  • Utilization of high energy photons (>10MV) with an optimal weight using a mixed energy technique is a practical way to generate a homogenous dose distribution while maintaining adequate target coverage in intact breast radiotherapy. This study represents a model for estimation of this optimal weight for day to day clinical usage. For this purpose, treatment planning computed tomography scans of thirty-three consecutive early stage breast cancer patients following breast conservation surgery were analyzed. After delineation of the breast clinical target volume (CTV) and placing opposed wedge paired isocenteric tangential portals, dosimeteric calculations were conducted and dose volume histograms (DVHs) were generated, first with pure 6MV photons and then these calculations were repeated ten times with incorporating 18MV photons (ten percent increase in weight per step) in each individual patient. For each calculation two indexes including maximum dose in the breast CTV ($D_{max}$) and the volume of CTV which covered with 95% Isodose line ($V_{CTV,95%IDL}$) were measured according to the DVH data and then normalized values were plotted in a graph. The optimal weight of 18MV photons was defined as the intersection point of $D_{max}$ and $V_{CTV,95%IDL}$ graphs. For creating a model to predict this optimal weight multiple linear regression analysis was used based on some of the breast and tangential field parameters. The best fitting model for prediction of 18MV photons optimal weight in breast radiotherapy using mixed energy technique, incorporated chest wall separation plus central lung distance (Adjusted R2=0.776). In conclusion, this study represents a model for the estimation of optimal beam weighting in breast radiotherapy using mixed photon energy technique for routine day to day clinical usage.

Trail and Campground Deteriorations, and Their Environmental Changes of Soil and Vegetation in Chiak Mountain National Park (치악산 국립공원의 등산로 및 야영장 훼손과 주변 토양 및 식생환경의 변화)

  • 권태호;오구균;권영선
    • Korean Journal of Environment and Ecology
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    • v.2 no.1
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    • pp.50-65
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    • 1988
  • Trail and campground deteriorations and their environmental changes of soil and vegetation were studied in Guryong district of Mt. Chiak National Park in 1988. The Widths of both the entire trail and the bare portion as the trail condition were significantly greater on the more heavily used trail. and regressions showed the significant positive relationship between slope along the trail and maximum depth of the trail($R^2$=0.35). Deterioration types of trail which had higher frequency for a total of 63 observations were rock exposure(48%), trail deepening(29%) and root exposure(27%) in the high order. And occurence of trail deterioration was considerably influenced by slope along the trail Ecological changes of soil and vegetation of trailsides were not found at a uniform tendency but could be grouped, by the types of user's disturbance. On campsites. tree damage types and their frequencies were basic as a means of which grasp the limits of user's impact. The area with damaged trees on campsite in pine forest were larger than that in mixed forest and the frequency by damage type of trees varied according to the distance from the core of campsite and to the crown layer. Water content, pH and hardness of soil. coverage of lower trees, species and individuals per 100$m^2$, basal areas of upper and middle layer of trees had significant relationship with the distance from campsite to forest. The range influenced by user's disturbance was more than 70-80m, md Staphylea bumalda, Morns bombycis, Stephanandra incisa and Securinega suffruticosa were considered as tolerant species to user's impact.

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Planning and Dosimetric Study of Volumetric Modulated Arc Based Hypofractionated Stereotactic Radiotherapy for Acoustic Schwannoma - 6MV Flattening Filter Free Photon Beam

  • Swamy, Shanmugam Thirumalai;Radha, Chandrasekaran Anu;Arun, Gandhi;Kathirvel, Murugesan;Subramanian, Sai
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.5019-5024
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    • 2015
  • Background: The purpose of this study was to assess the dosimetric and clinical feasibility of volumetric modulated arc based hypofractionated stereotactic radiotherapy (RapidArc) treatment for large acoustic schwannoma (AS >10cc). Materials and Methods: Ten AS patients were immobilized using BrainLab mask. They were subject to multimodality imaging (magnetic resonance and computed tomography) to contour target and organs at risk (brainstem and cochlea). Volumetric modulated arc therapy (VMAT) based stereotactic plans were optimized in Eclipse (V11) treatment planning system (TPS) using progressive resolution optimizer-III and final dose calculations were performed using analytical anisotropic algorithm with 1.5 mm grid resolution. All AS presented in this study were treated with VMAT based HSRT to a total dose of 25Gy in 5 fractions (5fractions/week). VMAT plan contains 2-4 non-coplanar arcs. Treatment planning was performed to achieve at least 99% of PTV volume (D99) receives 100% of prescription dose (25Gy), while dose to OAR's were kept below the tolerance limits. Dose-volume histograms (DVH) were analyzed to assess plan quality. Treatments were delivered using upgraded 6 MV un-flattened photon beam (FFF) from Clinac-iX machine. Extensive pretreatment quality assurance measurements were carried out to report on quality of delivery. Point dosimetry was performed using three different detectors, which includes CC13 ion-chamber, Exradin A14 ion-chamber and Exradin W1 plastic scintillator detector (PSD) which have measuring volume of $0.13cm^3$, $0.009cm^3$ and $0.002cm^3$ respectively. Results: Average PTV volume of AS was 11.3cc (${\pm}4.8$), and located in eloquent areas. VMAT plans provided complete PTV coverage with average conformity index of 1.06 (${\pm}0.05$). OAR's dose were kept below tolerance limit recommend by American Association of Physicist in Medicine task group-101(brainstem $V_{0.5cc}$ < 23Gy, cochlea maximum < 25Gy and Optic pathway <25Gy). PSD resulted in superior dosimetric accuracy compared with other two detectors (p=0.021 for PSD.

Selection Criteria of Harvesting and Logging Methods in Consideration of Forest Terrain Characteristics (산림지형특성(山林地形特性)을 고려한 산림수확방법(山林收穫方法) 및 집재방법(集材方法)의 선정기준)

  • Kim, Ki Weon
    • Journal of Korean Society of Forest Science
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    • v.82 no.2
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    • pp.195-206
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    • 1993
  • The purpose of this study is to provide a basis for establishing regional harvesting systems that ist the prerequisites for the forest mechanization. The factors restricting to the forest harvesting and logging methods from topographical aspects are studied for this purpose. Three main harvesting methods studied in this paper are : shortwood method, longwood method and full tree method. This study shows : the shortwood method is suitable for low, the longwood method for medium, the full tree method for high topographical conditions. For the logging methods, the focus of the study is on various ground based logging systems by animalpower, manpower, gravitation, wheeled & crawler vehicle and cable. The factors limiting the coverage of logging operation are slope and logging distance. The cable crane logging methods are classified by logging distance into short distance(to 300 or 400m), middle distance(to 700 or 800m) and long distance cable crane methods (over 700 or 800m). The wheeled vehicle method shows serious damages to forest resources, whereas the logging by log-line of the gravitation logging method and cable crane method tend to minimize such damages. The wheeled & crawler vehicle method also shows difficult to apply in the high slope conditions, whereas cable crane method can be applied to maximum 120% steep slope and uphill conditions.

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Flock composition, breeding strategies and farmers' traits of interest evaluation of Wollo highland sheep and their F1 crosses

  • Amare, Tadesse;Goshu, Gebeyehu;Tamir, Berhan
    • Journal of Animal Science and Technology
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    • v.60 no.5
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    • pp.14.1-14.12
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    • 2018
  • Background: Sheep production is a major component of the livestock sector in Ethiopia. The country owing to the large population of 30.70 million estimated numbers of sheep in the country and out of which about 72.14% are females, and 27.86% are males with diverse genetic resources. The real value of indigenous breeds was often under-estimated mostly due to their poor appearance and relatively low productivity. Developing countries in most cases opt for exotic breeds to increase animal productivity through crossbreeding or breed substitution without properly investigating the production potential of the indigenous breeds. The main objective of the research was to identify sheep flock composition and structure, farmers' traits of interest and breeding objective of Wollo highland sheep, and their $F_1$ crossbreed progenies. Results: Smallholder farmers' flock synthesized from breeding ewes, breeding rams, pre-weaned ewe lambs, pre-weaned ram lambs, unproductive ewes, castrated and fattened rams, with the percentage coverage of 29.2, 13.3, 15.5, 16.5, 12.4, and 12.5%, respectively. The maximum number of flock size was 289.0 sheep per flock and higher in the third stratum. The off-take rate percentage of the three strata presented as 21.9% in 1st stratum, 12% in the 2nd stratum, and 16.4% in the 3rd stratum and higher off-take rate recorded in the first stratum. Sheep producer's traits of interest ranked by growth rate (first), body size (second) and marketing value was third rank. Communal breeding (random mating), village based controlled breeding, mixed type and private ram controlled breeding practice were comprised of 39.7, 61.7, 52 and 71.3%, respectively. The percentages of ewes per flock composition were presented as 36.5, 27.1 and 25.5%, respectively in the 3rd stratum, 2nd stratum and 3rd stratum in the order of their importance's. Conclusion: Genetic improvement practices at smallholder sheep producers situation was showing promising outcome with indigenous Washera $F_1$ crossbred lambs and which designated for weaning rate, body size, marketing age, age at first lambing, good temperament and large litter size in the order of their rank. The contemporary breeding practice tendency indicated that, reduced flock size to improve flock productivity via crossbreeding practices.

Sequential localization with Beacon Nodes along the Seashore for Marine Monitoring Sensor Network (해안에 설치된 비콘 노드를 이용한 해양 모니터링 센서의 순차적인 위치 파악)

  • Kim, Chung-San;Kim, Eun-Chan;Kim, Ki-Seon;Choi, Young-Yoon
    • Journal of the Korea Society of Computer and Information
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    • v.12 no.4
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    • pp.269-277
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    • 2007
  • Wireless sensor network system is expected to get high attention in research for now and future owing to the advanced hardware development technology and its various applicabilities. Among variety of sensor network systems, the seashore and marine sensor network, which are extended to get sampling of marine resources, environmental monitoring to prevent disaster and to be applied to the area of sea route guidance. For these marine applications to be available, however, the provision of precise location information of every sensor nodes is essential. In this paper, the sequential localization algorithm for obtaining the location information of marine sensor nodes. The sequential localization is done with the utilization of a small number of beacon nodes along the seashore and gets the location of nodes by controling the sequences of localization and also minimizes the error accumulation. The key idea of this algorithm for localization is that the localization priority of each sensor nodes is determined by the number of reference nodes' information. This sequential algorithm shows the improved error performance and also provide the increased coverage of marine sensor network by enabling the maximum localization of sensor nodes as possible.

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A Study on the Current Status of National Library of Korea Subject Headings List through Utilization Analysis of Subject Headings (주제명 활용 분석을 통한 국립중앙도서관 주제명표목표의 현황 연구)

  • HyeKyung Lee;Yong-Gu Lee
    • Journal of the Korean Society for information Management
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    • v.40 no.2
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    • pp.157-182
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    • 2023
  • This study analyzed the structure and utilization of subject headings in the National Library of Korea Subject Headings List (NLSH) based on an analysis of subject headings assigned to 1,218,867 national bibliographies from 2003 to 2022. The findings of the study are as follows: Firstly, among all subject headings in the NLSH, there were 257,103 preferred terms, accounting for 50.2% of the total terms. Foreign language terms constituted 33% (169,466), while non-preferred terms comprised 12% (61,442). Among the preferred terms, 57,312 subject headings were used, accounting for 22.3%. However, it was observed that 54.7% (31,351) of these subject headings were assigned less than 5 times, indicating that only a small number of subject headings were frequently utilized. Secondly, the frequency of relationship indicators appeared in the order of RT, BT, and NT. The NLSH consisted of 12,602 top-level subject headings and 143,704 lowest-level subject headings, with a maximum depth of 17 levels. Thirdly, on average, 1.72 subject headings were assigned per bibliographic record. The number of subject headings assigned and the depth of the hierarchy increased for materials with more specific contents. Recent bibliographic records have been assigned more subject headings and deeper into the hierarchy of the NLSH. It was also found that the number of subject headings assigned per bibliography varied depending on the main class of KDC. Based on the findings, it is recommended to evaluate the coverage of terms in the NLSH, reorganize hierarchical relationships and depth of subject headings, and enhance the development of subdivisions within the NLSH.

Hospital-based home care reinbursement and service use for the elderly (노인의 의료기관 가정간호 급여청구 및 서비스 이용 현황)

  • Chin, Young-ran
    • 한국노년학
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    • v.29 no.2
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    • pp.645-656
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    • 2009
  • The purpose of this study was to address the current status of hospital-based home care(HBHC). We analyzed the data on HBHC from national electronic data information of Health Insurance Review Agency. Beside, we surveyed 75 hospital-based home care agency. In 2006, 20,343 elderly(64.0% from all HBHC user) used 333,889 visits(76.8%from all visits). Medical diagnosis was composed of circulatory disease including cerebrovascular diseases 41.3%, endocrine system disease including Diabetes mellitus 10.4%, neoplasm 9.7%. Some of subjects used HBHC in excess of maximum covered 8 visits a month by National Health Insurance, decubitus 7.0%, the cancer 5.4%, the diabetes 2.5%, the hypertension 1.1%, and the stroke 0.9%. This results will contribute to expand the coverage of hospital-based home care by National Health Insurance. There was distribution difference in medical diagnosis and nursing intervention between HBHC and Public health center-based home care(PBHC) subjects. Therefore, HBHC subjects had more severe medical diagnosis, and were intervened more injections, examinations, than PBHC subjects. These differences must be considered to set up functional role among the three types of home visit care.

The Gradient Variation of Thermal Environments on the Park Woodland Edge in Summer - A Study of Hadongsongrim and Hamyangsangrim - (여름철 공원 수림지 가장자리의 온열환경 기울기 변화 - 하동송림과 함양상림을 대상으로 -)

  • Ryu, Nam-Hyong;Lee, Chun-Seok
    • Journal of the Korean Institute of Landscape Architecture
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    • v.43 no.6
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    • pp.73-85
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    • 2015
  • This study investigated the extent and magnitude of the woodland edge effects on users' thermal environments according to distance from woodland border. A series of experiments to measure air temperature, relative humidity, wind velocity, MRT and UTCI were conducted over six days between July 31 and August 5, 2015, which corresponded with extremely hot weather, at the south-facing edge of Hadongsongrim(pure Pinus densiflora stands, tree age: $100{\pm}33yr$, tree height: $12.8{\pm}2.7m$, canopy closure: 75%, N $35^{\circ}03^{\prime}34.7^{{\prime}{\prime}}$, E $127^{\circ}44^{\prime}43.3^{{\prime}{\prime}}$, elevation 7~10m) and east-facing edge of Hamyangsangrim (Quercus serrata-Carpinus tschonoskii community, tree age: 102~125yr/58~123yr, tree height: tree layer $18.6{\pm}2.3m/subtree$ layer $5.9{\pm}3.2m/shrub$ layer $0.5{\pm}0.5m$, herbaceous layer coverage ratio 60%, canopy closure: 96%, N $35^{\circ}31^{\prime}28.1^{{\prime}{\prime}}$, E $127^{\circ}43^{\prime}09.8^{{\prime}{\prime}}$, elevation 170~180m) in rural villages of Hadong and Hamyang, Korea. The minus result value of depth means woodland's outside. The depth of edge influence(DEI) on the maximum air temperature, minimum relative humidity and wind speed at maximum air temperature time during the daytime(10:00~17:00) were detected to be $12.7{\pm}4.9$, $15.8{\pm}9.8$ and $23.8{\pm}26.2m$, respectively, in the mature evergreen conifer woodland of Hadongsongrim. These were detected to be $3.7{\pm}2.2$, $4.9{\pm}4.4$ and $2.6{\pm}7.8m$, respectively, in the deciduous broadleaf woodland of Hamyansangrim. The DEI on the maximum 10 minutes average MRT, UTCI from the three-dimensional environment absorbed by the human-biometeorological reference person during the daytime(10:00~17:00) were detected to be $7.1{\pm}1.7$ and $4.3{\pm}4.6m$, respectively, in the relatively sparse woodland of Hadongsongrim. These were detected to be $5.8{\pm}4.9$ and $3.5{\pm}4.1m$, respectively, in the dense and closed woodland of Hadongsongrim. Edge effects on the thermal environments of air temperature, relative humidity, wind speed, MRT and UTCI in the sparse woodland of Hadongsongrim were less pronounced than those recorded in densed and closed woodland of Hamyansangrim. The gradient variation was less steep for maximum 10 minutes average UTCI with at least $4.3{\pm}4.6m$(Hadongsongrim) and $3.5{\pm}4.1m$(Hamyansangrim) being required to stabilize the UTCI at mature woodlands. Therefore it is suggested that the woodlands buffer widths based on the UTCI values should be 3.5~7.6 m(Hamyansangrim) and 4.3~8.9(Hadongsongrim) m on each side of mature woodlands for users' thermal comfort environments. The woodland edge structure should be multi-layered canopies and closed edge for the buffer effect of woodland edge on woodland users' thermal comfort.

Characterization and annealing effect of tantalum oxide thin film by thermal chemical (열CVD방법으로 증착시킨 탄탈륨 산화박막의 특성평가와 열처리 효과)

  • Nam, Gap-Jin;Park, Sang-Gyu;Lee, Yeong-Baek;Hong, Jae-Hwa
    • Korean Journal of Materials Research
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    • v.5 no.1
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    • pp.42-54
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    • 1995
  • $Ta_2O_5$ thin film IS a promising material for the high dielectrics of ULSI DRAM. In this study, $Ta_2O_5$ thin film was grown on p-type( 100) Si wafer by thermal metal organic chemical vapo deposition ( MCCVD) method and the effect of operating varialbles including substrate temperature( $T_s$), bubbler temperature( $T_ \sigma$), reactor pressure( P ) was investigated in detail. $Ta_2O_5$ thin film were analyzed by SEM, XRD, XPS, FT-IR, AES, TEM and AFM. In addition, the effect of various anneal methods was examined and compared. Anneal methods were furnace annealing( FA) and rapid thermal annealing( RTA) in $N_{2}$ or $O_{2}$ ambients. Growth rate was evidently classified into two different regimes. : (1) surface reaction rate-limited reglme in the range of $T_s$=300 ~ $400 ^{\circ}C$ and (2: mass transport-limited regime in the range of $T_s$=400 ~ $450^{\circ}C$.It was found that the effective activation energies were 18.46kcal/mol and 1.9kcal/mol, respectively. As the bubbler temperature increases, the growth rate became maximum at $T_ \sigma$=$140^{\circ}C$. With increasing pressure, the growth rate became maximum at P=3torr but the refractive index which is close to the bulk value of 2.1 was obtained in the range of 0.1 ~ 1 torr. Good step coverage of 85. 71% was obtained at $T_s$=$400 ^{\circ}C$ and sticking coefficient was 0.06 by comparison with Monte Carlo simulation result. From the results of AES, FT-IR and E M , the degree of SiO, formation at the interface between Si and TazO, was larger in the order of FA-$O_{2}$ > RTA-$O_{2}$, FA-$N_{2}$ > RTA-$N_{2}$. However, the $N_{2}$ ambient annealing resulted in more severe Weficiency in the $Ta_2O_5$ thin film than the TEX>$O_{2}$ ambient.

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