• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제35권2호
• /
• pp.106-111
• /
• 2009

Bisphosphonates have been approved for Paget's disease, cancer-related hypercalcemia, bone involvement in multiple myeloma or solid tumors and osteoporosis. Although, underlying pathophysiological mechanisms remain unclear, it seems that bisphosphonates inhibit osteoclast precursor cells, modulate migratory and adhesive characteristics and induce apoptosis of osteoclasts. Furthermore impacts on angiogenesis, microenvironment and signal transduction between osteoclasts and osteoblasts. In this report, we present a case of oral bisphosphonates induced osteonecrosis of the mandible in a 84-year-old patient who received for two years. Two tapered screw vent implants(Zimmer, USA) were placed in the area of first and second molar. Two weeks later after crowns restored, some inflammatory signs and symptoms were observed on the second molar area. Sequestrum was formed and the sequestrum was removed with the implant. Frequent follow-up checks and oral hygiene maintenances were done and the first molar implant was restored. There is insufficient evidence suggests that duration of oral bisphosphonate therapy correlates with the development and severity of osteonecrosis. Therefore, dentists should not overlook the possibility of development of bisphosphonate induced osteonecrosis in patients who have taken oral forms of medication for less than three years.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제33권5호
• /
• pp.430-434
• /
• 2011

Extraskeletal osteochondroma is an uncommon benign tumor that arises in soft tissues lacking continuity with an adjacent bone and joint. Due to similar histopathological findings, extraskeletal osteochondroma is often misdiagnosed for a conventional osteochondroma, the most common benign tumor that arises from the epiphyseal plates of long bones. The pathogenesis of extraskeletal osteochondroma is unclear, but metaplasia of synovial mesenchymal tissue is the best supported etiology. The most common sites of extraskeletal osteochondroma are the hands and feet, and it is rarely found in the maxillofacial area. We present a case of a two-year-old boy with a giant extraskeletal osteochondroma that developed in the masticatory space of the mandible along with a review of the relevant literature.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제16권3호
• /
• pp.303-308
• /
• 1994

The ameloblastoma is considered to be a slowly growing locally invasive tumor with a high rate of recurrence if not removed adequately. Ameloblastoma generally dose not metastasize to distant places. In very rar case, ameloblastoma changed its histologic appearance to carcinoma or showed distant metastasie, these generally called malignant ameloblastoma. Inadequate surgical procedures, radiation therapy, and a long duration of this tumor seem to have significant relation to the development of metastasis. Therefore, adequate surgical treatment of the primary lesion plays an important role in the prevention of metastasis postoperatively. This report described an instance of malignant ameloblastoma and review of literature.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제38권6호
• /
• pp.379-383
• /
• 2012

Oromandibular dystonia (OMD) is a rare focal form of dystonia caused by prolonged muscles spasms in the mouth, face, and jaw. OMD can develop after dental treatment, as poorly aligned dentures or multiple tooth extraction may cause an impairment of proprioception in the oral cavity, leading to the subsequent development of dystonia. These repetitive involuntary jaw movements may interfere with chewing, swallowing, and speaking. We report here two cases of OMD after dental procedures.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제23권5호
• /
• pp.406-414
• /
• 2001

현재 악안면 보철 제작에 있어 재료로 실리콘이 제일 많이 사용되고 있으나 이 재료는 시간이 지남에 따라 점차 굳어져 가고 탄력성을 잃으며 원래의 색도 노랗게 변색되어 간다는 단점이 있다. 이러한 재료의 화학적 구성 단점 때문에 보철 생명력을 유지하기 위하여 환자들은 매 3년마다 새로운 보철물을 재 제작하여야 한다. 그렇다면 복잡했던 악안면 기공 과정을 다시 반복해야 하는 시간적, 물질적 손실을 감수해야 했다. 이러한 단점들을 보완하고 환자 피부색과 적합이 잘 되는 다양한 색의 실리콘 개발과 아울러 눈동자를 깜빡일 수 있는 인공 눈동자의 개발 등이 필요하며, 눈동자를 만드는데 사용되는 인공 수정체의 발전이 향후 악안면 보철 분야의 큰 과제라 할 수 있다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제29권5호
• /
• pp.298-300
• /
• 2003

Ameloblastomas are generally considered to be benign tumors of odontogenic epithelial origin with high local recurrence. Rarely ameloblastomas exhibit malignant behavior with development of metastases. In this report, we present a 19-year-old woman with ameloblastoma in the right ascending ramus and multiple recurrences. Eleven years after first therapy, ameloblastoma metastasized to ipsilateral submandibular lymph node. We also review literature about cause, treatment and work-up of malignant ameloblastoma.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제47권4호
• /
• pp.337-338
• /
• 2021

During recent decades, the three-dimensional (3D) approach in orthognathic surgery were introduced and adopted in clinical practice, providing practical advantages to orthognathic surgeons. Even when the 3D approach is assessed based on the current state of technological development, it has advantages in orthognathic surgery and has become an essential method. It is not sure what to come next in the development of the 3D approaches, It is clear that the 3D approach represents a milestone in the development of orthognathic surgery.

• 대한구순구개열학회지
• /
• 제10권1호
• /
• pp.17-22
• /
• 2007

The vertebrate upper lip forms from initially freely projecting maxillary, medial nasal, and lateral nasal prominences at the rostral and lateral boundaries of the primitive oral cavity. These facial prominences arise during early embryogenesis from ventrally migrating neural crest cells in combination with the head ectoderm and mesoderm and undergo directed growth and expansion around the nasal pits to actively fuse with each other. Initial fusion is between lateral and medial nasal processes and is followed by fusion between maxillary and medial nasal processes. Fusion between these prominences involves active epithelial filopodial and adhering interactions as well as programmed cell death. Slight defects in growth and patterning of the facial mesenchyme or epithelial fusion result in cleft lip with or without cleft palate, the most common and disfiguring craniofacial birth defect. This review will summarize the current understanding of the basic morphogenetic processes and molecular mechanisms underlying upper lip development.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제42권
• /
• pp.7.1-7.8
• /
• 2020

Maxillomandibular advancement (MMA) is effective for the treatment of obstructive sleep apnea (OSA). In previous studies, the airway was increased in the anteroposterior and transverse dimensions after MMA. However, the effect of the opposite of mandibular movement (mandibular setback) on the airway is still controversial. Mandibular setback surgery has been suggested to be one of the risk factors in the development of sleep apnea. Previous studies have found that mandibular setback surgery could reduce the total airway volume and posterior airway space significantly in both the one-jaw and two-jaw surgery groups. However, a direct cause-and-effect relationship between the mandibular setback and development of sleep apnea has not been clearly established. Moreover, there are only a few reported cases of postoperative OSA development after mandibular setback surgery. These findings may be attributed to a fundamental difference in demographic variables such as age, sex, and body mass index (BMI) between patients with mandibular prognathism and patients with OSA. Another possibility is that the site of obstruction or pattern of obstruction may be different between the awake and sleep status in patients with OSA and mandibular prognathism. In a case-controlled study, information including the BMI and other presurgical conditions potentially related to OSA should be considered when evaluating the airway. In conclusion, the preoperative evaluation and management of co-morbid conditions would be essential for the prevention of OSA after mandibular setback surgery despite its low incidence.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제40권
• /
• pp.18.1-18.6
• /
• 2018

Background: Clefts in newborns are associated with severe morphological and functional impairment. Especially the lip is of importance as if the treatment result is unsatisfactory, it can lead to psychological changes in the patient. Different operative procedures have been developed over the last decades. The aim of the presented study was the comparison of the surgical techniques according to Millard and Pfeifer regarding the temporal development of the postoperative symmetry of the lip height and mouth width. Methods: Digitized photographs of patients from the department of oral and maxillofacial surgery at the University of Göttingen were evaluated from 1979 to 1996. With a video analysis program, the lip height and mouth width were analyzed regarding the symmetry. We demonstrated the symmetry values over a period of 8 years in order to show the influence of growth on postoperative results. Results: The development of the vertical symmetry of the Philtrum and the lip vermillion on the cleft side in comparison to the healthy side behaves differently depending on Pfeifer and Millard. The lip height of the cleft lip was shorter in both techniques than on the healthy side, but Pfeifer's difference was significantly more pronounced. The lip vermillion height on the cleft side was slightly shorter in the Millard group and markedly larger in the Pfeifer group. Both techniques can achieve good symmetry results for the vertical dimension of the lip. According to Pfeifer, the development of the horizontal dimension on the cleft side is bigger within the first 4 years than on the healthy side; according to the Millard technique, the horizontal development is smaller. These differences are greater within the first 6 years and approach between the 6th and 8th year. Conclusions: The Millard technique demonstrates better results concerning the philtrum and vermillion symmetry during growth within the first 6 years. Over the whole study period, growth corrects the philtrum and vermillion symmetry within the Pfeifer group.