• Biotechnology and Bioprocess Engineering:BBE
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• v.10 no.4
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• pp.372-377
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• 2005

Aralia elata is an edible mountain vegetable. Angiogenesis, the formation of new blood vessels, is a process involving migration, proliferation and cell differentiation, as well as the formation of new capillary structures. Matrix metalloproteinases (MMPs) plays an important role in angiogenesis. The development of a functional vascular system requires a variety of growth factors, their receptors, and intracellular signals. This study examines the effects of water extracts from: (i) A. elata root bark (Aralia extracts); (ii) a combination of Aralia extracts and fibroblast growth factors (FGF-2) on cultured porcine coronary artery endothelial cells (PCAECs). Aralia extracts induced the migration of PCAECs, which was inhibited by MMPs inhibitors. Combining Aralia extracts and FGF-2 enhanced the migration and the secretion of MMP-2 and MMP­9 from PCAECs. We postulated that the Aralia extracts, which induced migrating activity in PCAECs, may be accomplished by increased secretion levels of MMP-2 and MMP-9.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.58 no.4
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• pp.795-800
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• 2009

Surface plasmon resonance (SPR) has been widely used for biological and chemical sensing applications. The present study investigates numerically the optical characteristics for the single Au film and bimetallic Ag/Au film SPR configurations by using the multiple beam interference matrix (MBIM) method. We use the prism coupling method, especially Kretschmann configuration for excitation of surface plasmon wave (SPW). The estimated results of reflectance, phase shift and magnetic field intensity enhancement factor are provided for finding out the optimum configuration with high sensitivity for SPR measurement. As a result, the optimum thicknesses are found to be 52 nm for a single Au film and 5 nm to 36 nm for bimetallic Ag-Au film. From the comparison of full width half maximum (FWHM) values for reflectance, phase shift, and enhancement of magnetic field intensity, it is concluded that the highest sensitivity can be obtained when using the phase shift for SPR sensor.

• Journal of Power System Engineering
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• v.19 no.1
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• pp.50-55
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• 2015

This study takes AC8A, which is a representative light weight alloy as matrix, and nickel as reinforcement for its superior properties. The manufacturing method applied in this study required low pressure for the infiltration of the metal matrix into the reinforcement. Porous Ni was applied as preform. The fabrication was conducted under 0.3 MPa at 600, 700 and 750 degrees centigrade, respectively. Intermetallic compounds Al3 generated between Al and Ni were observed in the composites. Microstructure, Vickers' hardness and wear characteristics of the composites were also investigated. The result indicates that the structures of compounds created at 650 degree centigrade were distributed densely; the grain size of the substances and the compounds was increased with the infiltration temperature.

• Korean Management Science Review
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• v.15 no.1
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• pp.49-62
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• 1998

The purpose of this paper is to develope a large-scale simplex method program LPAKO. Various up-to-date techniques are argued and implemented. In LPAKO, basis matrices are stored in a LU factorized form, and Reid's method is used to update LU maintaining high sparsity and numerical stability, and further Markowitz's ordering is used in factorizing a basis matrix into a sparse LU form. As the data structures of basis matrix, Gustavson's data structure and row-column linked list structure are considered. The various criteria for reinversion are also discussed. The dynamic steepest-edge simplex algorithm is used for selection of an entering variable, and a new variation of the MINOS' perturbation technique is suggested for the resolution of degeneracy. Many preprocessing and scaling techniques are implemented. In addition, a new, effective initial basis construction method are suggested, and the criteria for optimality and infeasibility are suggested respectively. Finally, LPAKO is compared with MINOS by test results.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.1
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• pp.156-160
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• 2007

Surface plasmon resonance(SPR) has been widely studied for biological and chemical sensing applications. The present study conducts numerical simulation for the single and bimetallic layer SPR configurations by using the multiple beam interference matrix(MBIM) method to investigate the influence of wave interference and complex refractive indices of materials on optical characteristics such as reflectance and optical phase shift which are used for sensing. First, calculated reflectances are compared with experimental data for validation. In addition, in the single film structures this study finds out the appropriate film thicknesses with minimum reflectance for cases of gold film and silver film. For a bimetallic silver-gold film structure, in particular, the bimetallic film thicknesses that has the minimum reflectance are found 36 nm for silver and 5 nm for gold. From the results, the use of phase shift would be useful compared to reflectance in determining the SPR configuration because the phase shift becomes more sensitive than reflectance.

• Steel and Composite Structures
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• v.15 no.2
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• pp.175-202
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• 2013

The super convergent laminated composite beam element is newly derived for the lateral stability analysis. For this, a theoretical model of the laminated composite beams is developed based on the first-order shear deformation beam theory. The present laminated beam takes into account the transverse shear and the restrained warping induced shear deformation. The second-order coupling torque resulting from the geometric nonlinearity is rigorously derived. From the principle of minimum total potential energy, the stability equations and force-displacement relationships are derived and the explicit expressions for the displacement parameters are presented by applying the power series expansions of displacement components to simultaneous ordinary differential equations. Finally, the member stiffness matrix is determined using the force-displacement relationships. In order to show accuracy and superiority of the beam element developed by this study, the critical lateral buckling moments for bisymmetric and monosymmetric I-beams are presented and compared with other results available in the literature, the isoparametric beam elements, and shell elements from ABAQUS.

• Structural Engineering and Mechanics
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• v.26 no.2
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• pp.163-178
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• 2007

In practical engineering, the uncertain concept plays an important role in the control problems of the vibration structures. In this paper, based on matrix perturbation theory and interval finite element method, the closed-loop vibration control system with uncertain parameters is discussed. A new method is presented to develop an algorithm to estimate the upper and lower bounds of the real parts and imaginary parts of the complex eigenvalues of vibration control systems. The results are derived in terms of physical parameters. The present method is implemented for a vibration control system of the frame structure. To show the validity and effectiveness, we compare the numerical results obtained by the present method with those obtained by the classical random perturbation.

• Structural Engineering and Mechanics
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• v.67 no.4
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• pp.327-336
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• 2018

In this study, an efficient damage index is proposed to identify multiple damage cases in structural systems using the concepts of frequency response function (FRF) matrix and strain energy of a structure. The index is defined based on the change of strain energy of an element due to damage. For obtaining the strain energy stored in elements, the columnar coefficients of the FRF matrix is used. The new indicator is named here as frequency response function strain energy based index (FRFSEBI). In order to assess the performance of the proposed index for structural damage detection, some benchmark structures having a number of damage scenarios are considered. Numerical results demonstrate that the proposed index even with considering noise can accurately identify the actual location and approximate severity of the damage. In order to demonstrate the high efficiency of the proposed damage index, its performance is also compared with that of the flexibility strain energy based index (FSEBI) provided in the literature.

• The Journal of Korea Robotics Society
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• v.9 no.3
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• pp.178-184
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• 2014

Tendon driven robot mechanisms have many advantages such as allowing miniaturization and light-weight designs and/or enhancing flexibility in the design of structures. When designing or analyzing tendon driven mechanisms, it is important to determine how the tendons should be connected and whether the designed mechanism is easily controllable. Graph representation is useful to view and analyze such tendon driven mechanisms that are complicatedly interconnected between mechanical elements. In this paper, we propose a method of generalized graph representation that provides us with an intuitive analysis tool not only for tendon driven manipulators, but also various other kinds of mechanical systems which are combined with tendons. This method leads us to easily obtain structure matrix - which is the one of the most important steps in analyzing tendon driven mechanisms.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2004.10a
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• pp.175-179
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• 2004

Since the electromagnetic properties of fiber reinforced polymeric composites can be tailored effectively by adding small amount of electromagnetic powders to the matrix of composites, they are plausible materials for fabricating the radar absorbing structures (RAS) of desired performance. In order to design the effective electromagnetic wave (EM) absorber with the fiber reinforced polymeric composites, the electromagnetic characteristics with respect to the constituents of the composite should be available in the target frequency band. In order to describe the dielectric behavior of low loss unidirectional fiber reinforced composite, theoretical models and mixture equations for estimating its dielectric constant were proposed with respect to the fiber, matrix volume fractions and fiber orientations, and verified by the experiments. From the investigation, it was found that the suggested binary mixture rules agreed well with the experimental results.