• Nuclear Engineering and Technology
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• 제54권11호
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• pp.4244-4252
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• 2022

The accuracy of Monte Carlo (MC) simulations in estimating the computed tomography radiation dose is highly dependent on the accuracy of CT scanner model. A system was developed to observe the 3D model intuitively and to calculate the X-ray energy spectrum and the bowtie (BT) filter model more accurately in Monte Carlo N-particle (MCNP). Labview's built-in Open Graphics Library (OpenGL) was used to display basic surfaces, and constructive solid geometry (CSG) method was used to realize Boolean operations. The energy spectrum was calculated by simulating the process of electronic shooting and the BT filter model was accurately modeled based on the calculated shape curve. Physical data from a study was used as an example to illustrate the accuracy of the constructed model. RMSE between the simulation and the measurement results were 0.97% and 0.74% for two filters of different shapes. It can be seen from the comparison results that to obtain an accurate CT scanner model, physical measurements should be taken as the standard. The energy spectrum library should be established based on Monte Carlo simulations with modifiable input files. It is necessary to use the three-segment splicing modeling method to construct the bowtie filter model.

• Journal of Microbiology and Biotechnology
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• 제33권8호
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• pp.1091-1100
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• 2023

Human papillomavirus (HPV) types 16 and 18 are the major causes of cervical lesions and are associated with 71% of cervical cancer cases globally. However, public health infrastructures to support cervical cancer screening may be unavailable to women in low-resource areas. Therefore, sensitive, convenient, and cost-efficient diagnostic methods are required for the detection of HPV16/18. Here, we designed two novel methods, real-time ERA and ERA-LFD, based on enzymatic recombinase amplification (ERA) for quick point-of-care identification of the HPV E6/E7 genes. The entire detection process could be completed within 25 min at a constant low temperature (35-43℃), and the results of the combined methods could be present as the amplification curves or the bands presented on dipsticks and directly interpreted with the naked eye. The ERA assays evaluated using standard plasmids carrying the E6/E7 genes and clinical samples exhibited excellent specificity, as no cross-reaction with other common HPV types was observed. The detection limits of our ERA assays were 10⁰ and 10¹ copies/µl for HPV16 and 18 respectively, which were comparable to those of the real-time PCR assay. Assessment of the clinical performance of the ERA assays using 114 cervical tissue samples demonstrated that they are highly consistent with real-time PCR, the gold standard for HPV detection. This study demonstrated that ERA-based assays possess excellent sensitivity, specificity, and repeatability for HPV16 and HPV18 detection with great potential to become robust diagnostic tools in local hospitals and field studies.

• 디지털융복합연구
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• 제11권5호
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• pp.347-354
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• 2013

양질의 의료 서비스를 요구하는 환자들은 증가하는 반면 의사나 간호사와 같은 전문 의료 인력은 한정되어 있어 그들에게 가해지는 업무 부담이 과중하게 부여되고 있는 실정이다. 이러한 문제를 해결하기 위한 대안으로 USN(Ubiquitous Sensor Network)을 이용한 환자 모니터링 시스템이 대두되고 있다. 본 논문에서는 USN을 산부인과에 적용하여 간호사의 업무 부담을 줄이기 위해 산모 모니터링 시스템 모델을 설계하였다. 효율성 평가는 서울소재 대학병원(S, K 병원) 두 곳을 모델로 설정하여 의사의 처방에 따른 측정 주기를 산출하여 실시하였으며, 그 결과는 간호사 1인이 12명의 환자(자연분만 6명, 자연분만 외 출산 6명)를 케어하는 경우 입원기간(5일 기준) 동안에 1,260분이 경감되는 것으로 나타났다. 또한 간호사의 기존 업무량과 모니터링 시스템 적용 후 업무량을 비교해 보았을 때 자연분만 산모의 경우 산모 수가 1명씩 증가함에 따라 하루에 50분씩, 자연분만 외 수술 산모의 경우 산모 수가 1명씩 증가함에 따라 하루에 130분씩 업무량 감소 효과가 있는 것으로 나타났다.

• Clinical and Experimental Pediatrics
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• 제62권12호
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• pp.450-455
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• 2019

Background: Lipid accumulation product (LAP) is associated with the presence and severity of nonalcoholic fatty liver disease (NAFLD) in adults. Purpose: Here we evaluated the ability of LAP to predict NAFLD in obese children. Methods: Eighty obese children (38 girls; age 6-18 years) were included. Anthropometric measurements and biochemical values were obtained from the patients' medical records. LAP was calculated as [waist circumference (WC) (cm) - 58]×triglycerides (mmol/L) in girls; [WC (cm) - 65]×triglycerides (mmol/L) in boys. The minLAP and adjLAP were described (3% and 50% of WC values, respectively) and the total/high-density lipoprotein cholesterol index (TC/HDL-C) was calculated. NAFLD was observed on ultrasound, and patients were divided into 3 groups by steatosis grade (normal, grade 0; mild, grade 1; moderate-severe, grade 2-3). The area under the curve (AUC) and appropriate index cutoff points were calculated by receiver operator characteristic analysis. Results: LAP was positively correlated with puberty stage (rho=0.409; P<0.001), fasting insulin (rho= 0.507; P<0.001), homeostasis model assessment of insulin resistance (rho=0.470; P<0.001), uric acid (rho=0.522; P<0.001), and TC/HDL-C (rho=0.494; P<0.001) and negatively correlated with HDL-C (rho=-3.833; P<0.001). LAP values could be used to diagnose hepatosteatosis (AUC=0.698; P=0.002). The LAP, adjLAP, and minLAP cutoff values were 42.7 (P=0.002), 40.05 (P=0.003), and 53.47 (P= 0.08), respectively. For LAP, the differences between the normal and mild groups (P=0.035) and the normal and moderate-severe groups were statistically significant (P=0.037), whereas the difference between the mild and moderate-severe groups was not (P>0.005). There was a statistically significant difference between the normal and mild groups for adjLAP (P=0.043) but not between the other groups (P>0.005). There was no significant intergroup difference in minLAP (P>0.005). Conclusion: LAP is a powerful and easy tool to predict NAFLD in childhood. If LAP is ≥42.7, NAFLD should be suspected. This is the first study to assess LAP diagnostic accuracy for childhood obesity.

• 비교문화연구
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• 제43권
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• pp.79-113
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• 2016

본고는 근대 일본 여성운동의 궤적을 '모성' '참정권' '전쟁'이라는 세 가지 키워드를 중심으로 통시적으로 고찰하되, 궁극적으로는 이 모든 것이 일본이라는 '국가'와 어떤 관계를 이루었는가라는 관점에서 다룬 것이다. 특히 국가의 입장에서 여성에 대한 정책 등을 살핀 것이 아니라 여성들의 입장에서, 즉 이들이 '국가를 향해 어떠한 기대를 품었는가'라는 관점에서 히라쓰카 라이초(平塚らいてう)와 이치카와 후사에(市川房枝)라는 두 인물을 축으로 삼아 다루었다는 특징이 있다. '국가에 의한 모성의 보호'를 기대했던 히라쓰카는 신부인협회(新婦人協會)를 통해 전개했던 의회 청원운동의 실패를 끝으로 국가에 대한 기대를 사실상 접게 된다. 반면 미국 여성참정권 획득에 자극을 받은 이치카와는 여성의 참정권 획득을 위한 의회 청원운동을 포기하지 않았으며, 이 때문에 - 비록 대개는 생활문제의 개선이라는 방식이기는 했지만 - 당국으로부터의 전쟁협력 요구에도 응하지 않을 수 없었다. 이처럼 국가를 향한 '기대'는 근대 일본 여성운동을 견인하는 주된 원동력이었지만, 한편으로는 - 이치카와가 공직에서 추방되는 것으로 상징되듯- 침략전쟁의 협력의 오명을 쓰게 되는 원인이 되기도 했다.

• 가족자원경영과 정책
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• 제20권1호
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• pp.61-87
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• 2016

The purpose of this study is to demonstrate how having a family care program in the workplace for working women with preschool children affects these women's work and family life. This study employs a panel analysis based on data from the Korean Longitudinal Survey of Women and Families. The major results are as follows. First, financial support for nursery care is only significantly related to the turnover of married women with preschool children. Second, the negative effects of work on the family are significantly influenced by financial support for nursery care and maternity leave. Third, financial support for nursery care is also significantly related to the positive effects of work on the family. In conclusion, a family-friendly care program including financial support for nursery care and maternity leave in the workplace is an important support system for working mothers in raising their children.

• 한국의류학회지
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• 제44권4호
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• pp.708-726
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• 2020

This study develops leggings patterns for pregnant women with increased needs in utilization and necessity. It provides basic data for the development of leggings for pregnant women. The pattern was deformed by analyzing the leggings of U company, and simulated using the DC Suite Program. SPSS 24.0 was used for the analysis. As a result of the appearance evaluation, the primary pattern had many spaces in the thighs, calves, and the upper part; in addition, wrinkles occurred in the upper part and the knee part. The length of the leggings was long and agglomeration in the ankle appeared. Wrinkles were reduced by setting the hip circumference, hip width, and leggings length to reflect the results of the primary in the case of the secondary pattern. A pattern was developed that closely adhered to the body without any wrinkles in the appearance evaluation of the final pattern. Future studies should examine legging patterns of pregnant women according to the material change. Wearing evaluation and appearance evaluation should be done by making actual leggings for pregnant women, not 3D simulation.

• 가정과삶의질연구
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• 제27권2호
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• pp.191-201
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• 2009

The Korean Government has recently prepared the comprehensive five-year basic plan (2006-2010) to deal with low fertility and population ageing. The basic plan aims at recovering the fertility rate to the appropriate level and improving the social and economic systems in preparation for the aged society. The main objective of this study was to examine the effects of fertility policies on childbirth by birth order. The data came from 1,729 adults who gave birth to babies in 2007 and 991 adults as the control group. The serial logistic regression analyses revealed that establishing the health and nutrition system for maternity and children, and expanding of tax and social insurance benefit were effective policy measures to increase childbirths of first children, while the policy measures establishing the health and nutrition system for maternity and children, supporting for daycare and pre-school education, and work-life balance were effective to childbirths of second or third children in 2007. However, the policies of supporting for costs of test-tube baby and expanding childcare infra didn't have any significant influences on childbirths in 2007. The implications of study results were discussed.

• 가족자원경영과 정책
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• 제14권1호
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• pp.97-118
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• 2010

The purpose of this study is to provide background information to help develop family-friendly policies which aid in the ability for employees to balance family and work, and to increase the effectiveness and feasibility of these policies at work sites. We surveyed the performance and usage of work-family balance policies among working mothers with young children. We also examined the factors influencing the job satisfaction of working mothers. The study sample consisted of 237 working mothers with young children. We found that family economic status, working mother's experience of family leave or maternity leave, and easiness of policy use are important factors in a working mother's job satisfaction. Especially when individual and job characteristics are controlled, the most influential factor on working mothers' job satisfaction was the experience of family leave or maternity leave. In addition, the easiness of family-friendly policy use was a significant factor in working mothers' job-satisfaction.

• 대한간호
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• 제36권2호
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• pp.49-63
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• 1997

This study was performed to provide preliminary data for the development of a useful instrument to measure the effect of sex education. The study was conducted with the voluntary participation of 155 college students enrolled in the course "Sexuality and Relationship" at Y university in Seoul. At the end of that course, they were asked to write freely about the change they had experienced on sexuality. All meaningful statements were elicited and classified into 7 categories; "Change of Knowledge", "Enlightenment", "Change of Attitude on Sexuality", "Buildup of Ability", "Buildup of. Identity", "Change of Emotion", "Change of Behavior:' There were significant changes in the areas of knowledge(28. 6%), enlightenment(27.4%), and attitudes(20.3%) about sexuality among these 7 categories. The Change of Knowledge category consists of 3 areas: "concretion of knowledge", "increase of information", and "correction of misunderstanding." In the category of Enlightenment, total 12 areas are included: "sex role", "erception of lack of knowledge", "importance of family", "life plan", "parent role", "value of life", "equality", "sexual autonomy", "importance of sexuality", "freedom of sexuality", "perception of sexual problem", and "meaning of love." The Attitude Change category consists of 8 areas. These are "being natural", "being progressive", "being sensitive", "being truthful", "being expressive", "being cautious", "being responsible", and "being confident". The category of Buildup of Ability includes 4 areas: "problem solving", "sex education", "relationship", and "communication". The category of Buildup of Identity includes "sexual identity", and "value of sexuality". The Emotional Change category includes 3 areas: "positive feeling", "negative feeling", and "breaking from negative feeling on sexuality". The Behavior Change category includes "sex-related behavioral change". In conclusion, up to now most researches on sex education effect measures only changes of knowledge, attitude, and behavior. But we believe the changes in "Enlightenment", "Buildup of Ability", "Buildup of Identity", "Change of Emotion", should be included in addition to knowledge, attitude, and behavior in the development of an instrument to measure the sex education effects. And the effect of sex education should measure the degree of learning of autonomy, enlightenment, and ability of behavior and so on rather than studying the simple changes in sexuality.enment", "Buildup of Ability", "Buildup of Identity", "Change of Emotion", should be included in addition to knowledge, attitude, and behavior in the development of an instrument to measure the sex education effects. And the effect of sex education should measure the degree of learning of autonomy, enlightenment, and ability of behavior and so on rather than studying the simple changes in sexuality.ng the simple changes in sexuality.