• 대한간호학회지
• /
• 제25권2호
• /
• pp.244-258
• /
• 1995

아기의 출생은 부모에게 환경적, 신체적, 정신적 부담을 준다. 이렇게 부모가 된 사람들은 부모역할 수행시 어려움을 겪고 있고, 그 중에서도 어머니가 아버지보다 역할수행시 더 많은 어려 움을 겪고 있다고 한다. 본 연구는 생후 8개월 된 아기 어머니들을 대상으로 역할이 론을 토대로 모성역할 획득에 영향을 주는 요인들로 가설적 모형을 구축하고, 이의 적합성을 검정하므로 써 어머니들의 모성역할 획득을 촉진하기 위하여 필요한 간호 정보를 제공하려고 한다. 본 연구는 문헌고찰을 통하여 모성역할 긴장과 모성역할 획득에 영향을 주는 요인으로 일상생활의 시간적 여유, 아기 기질, 사회적 지지가 포함되었고, 모성역할 긴장이 모성역할 획득에 영향을 주는 것으로 이론적 기틀을 구성하였다. 연구도구로는 모성역할 획득 중 모성 정체감을 측정하기 위해 Osgood(Walker et al., 1986a에서 인용)도구, 모성역할 수행을 측정하기 위해 수정보완 된 Gibaud-Wallston(1977)도구와 어머니가 지각한 모아 상호작용정도 도구를 이용하였고, 모성역할 긴장측정에는 수정 보완된 Hobbs(정, 1985에서 인용)도구를 이용하였다. 아기 기질은 수정 보완한 The degree of thor inventory(Mercer, 1986 에서 인용), 남편의 정신적지지 측정은Taylor(Durrett, 1986에서 인용)의 도구를 이용하였고, 일상생활의 시간적 여유, 남편의 신체적 지지 및 주위의 지지측정은 연구자가 개발한 도구를 사용하였다. 1993년 1월부터 1994년 1월까지 대전시 5개 보건소에 등록된 대상자들에게 우편으로 설문지를 보내어 221명이 회수되어 회수율이 약72%였다. 일반적인 서술적 자료 분석은 SPSS PC+ 를 이용하였고, 가설적 모형은PC-LISREL 7.13 (Joreskkog & Sorbom,1988)프로그램을 이용하여 공변량구조분석을 하였다. 연구결과는 다음과 같다. 모성역할 획득에 모성역할 긴장, 일상생활의 시간적 여유, 아기 기질, 사회적 지지가 영향을 주며, 모성역할 긴장에는 일상생활의 시간적 여유, 아기 기질, 사회적지지가 영향을 준다고 설정된 가설적 모형〈Figure 1〉의 분석 결과 전반적 지수는 자유도 23에 카이자승치 60.17, GFI와 AGFI의 값은 .944, .891였고, NFI와 NNFI의 값은 .8823, .7932 이었다. 그러나 세부적 지수 중 모성역할 긴장에서 모성역할획득으로의 경로, 일상생활의 시간적 여유에서 모성역할 획득으로의 경로, 아기 기질에서 모성역할 획득으로의 경로의 고정지수가 절대치 2에 미치지 못하여, 세 경로계수를 영(0)으로 고정시킬 필요가 있었다. 따라서 더 간명하며 부합도가 좋은 모형을 찾기 위하여 가설적모형에서 고정지수가 낮은 경로 부터 고정시켜 나가 세경로(모성 역할 긴장에서 모성역할 획득, 일상생활의 시간적 여유에서 모성역할 획득, 아기 기질에서 모성역할획득)를 고정시킨 수정 모형 의 PFI (간명도)가 .5986으로서 가설적모형의 PFI(간명도) .5636보다 커 부합도 를 손상하지 않고 더 간명한 모형으로 나타났다. 수정모형 의 고정 지수를 살펴 본 결과 절대 치 2에 미치지 못하는 경로는 나타나지 않았다. 공변량구조분석 결과 나타난 변인간의 관계를 보면 가) 모성역할 긴장은 사회적 지지가 많을수록(Lisrel Estimates=-1.591), 아기 기질이 순하다고 생각할수록(Lisrel Estimates=-.266), 일상생활의 시간적 여유가 많을수록(Lisrel Estimstes=-1.771) 낮았고, 나) 모성역할 획득은 사회적 지지가 많을수록(Lisrel Estimates=1.120) 잘 되었다.

• 모자간호학회지
• /
• 제2권1호
• /
• pp.5-20
• /
• 1992

This study was undertaken to identify the levels and affecting factors of the maternal role attainment(MRA) in the primipara during the postpartum period. The healthy ninety primiparous from the one university hospital and two local clinics in KwangJu city were selected and two Semantic Differential Scales (SD-Myself as Mothers, SD-My Baby) and the Pharis Self Confidence Scale were used in this study. Questionnaires were distributed at the 3rd days and the 4-6 weeks of the primiparous not showing any complication after normal delivery. The data collected were analysed statistically using t-test, Pearson's Product Moment Correlation Coefficient and ANOVA. The results obtained were summarized as follows; 1) On the 3rd day after the delivery, the scores of SD-myself as mother, SD-baby and Pharis Self Confidence were 70.6 points, 73.6 points and 78.6 points, respectively, showing the low level of MRA. 2) On the 4-6 weeks after delivery, the score of SD-myself as mother, SD-baby and Pharis Self Confidence were 72.8 points, 77.9 points, and 86.9 points, respectively, indicating the moderate level of MRA. 3) The mean scores of the SD scale and the Pharis Self Confidence during the postpartum periods were higher than those of the 3rd days, showing the SD-myself as mother (t=-2.09, P<.05), SD-baby(t=-4.12, P<.001), Pharis Self Confidence(t=-6.59, P<.001), respectively. 4) Positive correlations (r=.24$\sim$.69) were shown in the concepts related to the MRA and the cognitive-motor skill components and cognitive-affective skill components of the MRA became harmonious over time. 5) The relationships between the score of the MRA and the demographic and obstetric variables were as follows ; a) the score of the MRA in the twenties was higher than those of the thirties. b) the group with higher educational background showed higher MRA socres than the group with lower one. c) those who wanted pregnancy sustenance had higher MRA scores than those who did not. d) the group that did think of festus-feature represented higher MRA scores than those who did not. e) the group of mothers who have the daughters showed higher MRA scores than those who have boys. It can be concluded from the results that the MRA in the primiparous increased gradually, and that the cognitive-motor skills and cognitive-affective skills became harmonious over time. The level of the MRA was affected partly by the mothers general, obstetrical variables. Following suggestion were made oil the basis of the present study ; a) The longitudinal study on the MRA is needed. b) Multivariate analyses should be done for the identification of the factors influcening on the MRA. c) Education program for primiparous mother should be designed and developed to improve the MRA.

• Asian-Australasian Journal of Animal Sciences
• /
• 제26권10호
• /
• pp.1379-1387
• /
• 2013

In a majority of mammals, male infants have heavier body mass and grow faster than female infants. Accordingly, male offspring nursing requires a much greater maternal energy contribution to lactation. It is possible that the maternal-fetal immunoendocrine dialog plays an important role in female preparation for lactation during pregnancy. Immune system genes are an integral part of gene regulatory networks in lactation and tumor necrosis factor alpha ($TNF{\alpha}$) is a proinflammatory cytokine that also plays an important role in normal mammary gland development. The aim of this study was to evaluate the influence of the sex of calf and/or the -824A/G polymorphism in the promoter region of $TNF{\alpha}$ gene on milk performance traits in Black Pied cattle over the course of lactation. We also studied the allele frequency differences of -824A/G variants across several cattle breeds, which were bred in different climatic conditions. The G allele frequency decreased gradually over the course of lactation events in the Black Pied dairy cattle because of a higher culling rate of cows with the G/G genotype (p<0.001). In contrast to the genotypes A/A and A/G, cows with G/G genotype showed significant variability of milk and milk fat yield subject to sex of delivered calf. Milk yield and milk fat yield were significantly higher in the case of birth of a bull calf than with a heifer calf (p<0.03). The G allele frequency varies from 48% to 58% in Grey Ukrainian and Black Pied cattle to 77% in aboriginal Yakut cattle. Our results suggest that the $TNF{\alpha}$-824A/G gene polymorphism may have an influence on the reproductive efforts of cows over the course of lactation events depending on the sex of progeny. Allocation of resources according to sex of the calf allows optimizing the energy cost of lactation. This may be a probable reason for high G allele frequency in Yakut cattle breeding in extreme environmental conditions. Similarly, the dramatic fall in milk production after birth of a heifer calf increases the probability of culling for the cows with the G/G genotype in animal husbandry.

• 대한의생명과학회지
• /
• 제2권2호
• /
• pp.211-222
• /
• 1996

수태기간중 태아가 모체에 의해 면역학적으로 거부반응을 일으키지 않고 동종이식 상태로 유지되는 기작을 밝히는 연구의 일환으로 C3H/HeJ계의 암컷 생쥐와 DBA/2계의 수컷 생쥐를 교배하여 모체에서 발생되는 체계적인 면역기능 및 국소적 면역기능현상에 대하여 연구하고자 수태기 간별로 비 장 및 자궁으로 들어가는 림프절에서 T세포 및 B세포의 아형을 측정하였고 자연살해 세포의 활성도를 측정하였다. 또한 수태혈청 및 수태성 호르몬이 자연살해세포의 활성도에 미치는 영향을 알아보았다. 각 수태기간별로 비장세포에 있어서 T세포와 B세포의 아형을 관찰한 결과, Thy-1.2$^{+}$세포는 수태기간중 중기 이후에 감소하기 시작하여 수태 4기에는 대조군에 비하여 유의하게 감소하였으며 수태말기에는 회복하였다. L3T4$^{+}$세포도 Thy-1.2$^{+}$ 세포와 비교하여 비슷한 경향으로 감소 또는 증가하였다. Ly2$^{+}$세포는 수태중기 이후부터 대조군에 비하여 유의하게 증가하였으며 B세포는 수태중기 이후부터 수태말기까지 계속 증가하였다. 비장에 있어서 자연살해세포의 세포독성은 수태 5일에서 수태 8일 사이에 가장 증가하였으며 그 이후는 대조군 수준으로 감소하였다. 정상혈청 및 수태혈청의 자연살해세포의 세포독성에 대한 영향을 수태시기별로 조사한 결과, 정상혈청과 수태혈청 모두 자연살해세포의 세포독성을 유의하게 억제하였으며, Progesterone은 시험관내실험과 생체내 실험 모두 약리적인 농도이상에서 농도에 의존적으로 자연살해세포의 세포독성을 증가시켰으며, HCG는 5 unit/ml에서 5000 unit/ml까지 처리농도에 비례하여 자연살해세포의 세포독성을 억제하였다. 자궁으로 들어가는 림프절에서 T세포의 아형은 Thy-1.2$^{+}$세포는 수태 2기부터 증가하여 대조군에 보다 유의하게 증가하였으며, L3T4$^{+}$세포의 유의한 변화없이 Ly2$^{+}$세포가 수태 2기 이후부터 대조군에 비하여 유의하게 증가하였고 분만 직전에는 조금 감소하였다. 자궁으로 들어가는 림프절에서의 자연살해세포의 세포독성은 착상직후 대조군에 비하여 유의하게 증가하였으며, 수태중기와 수태후기에도 대조군에 비하여 세포독성이 증가하였으며, 같은 시기의 비장세포의 자연살해세포의 세포독성보다 높게 나타났다.

• 대한간호학회지
• /
• 제26권1호
• /
• pp.165-176
• /
• 1996

The purpose of this study was to contribute to family nursing in the areas of reducing stress and improving coping for parents of mentally retarded children. Data were collected through self-report questionnaires during a period of 2 months between November 1994 and January 1995 in the Kyoung-in area. The subjects consist of 176 parents (88 mothers and 88 fathers) of mentally retarded children attending schools for the handicapped. The levels of general stress and of parental role stress were measured with the General stress scale and the Parental role stress scale, respectively. The coping scale developed by Folkman ＆ LaZarus was adopted to measure the level of coping, and the patterns of adaptation scale developed by Damrosch ＆ Perry was adopted to measure the patterns of adaptation. The data were analyzed by a SAS program using Fisher's exact test, paired t-test, and oneway ANOVA. The results are as follows ; 1. The level of general stress was significantly higher in mothers than in fathers. Mothers experienced a significantly greater level of parental role stress than fathers did. No significant difference in the level of coping was observed between mothers and fathers. There were differences in maternal and paternal patterns of adaptation. 2. The adaptation pattern of fathers was different according to their level of general stress, parental role stress and coping. The adaptation pattern of mothers was not different according to their level of general stress and parental role stress, but was according to their level of coping. 3. General stress experienced by fathers was different according to education, health status and support from their spouses. Satisfaction with family life, satisfaction with spouse and the support from spouse influenced coping used by fathers. Their level of parental role stress was not associated with any of their general characteristics. 4. In mothers, the level of general stress was different according to their health status, the level of parental role stress was related to satisfaction with family life and satisfaction with spouse. Their level of coping was associated with the sup port from spouse. The above findings indicate that mothers did not have more coping strategies than fathers did, despite the results which showed that mothers experienced greater stress than fathers did. Especially, the adaptation pattern of mothers was different according to their level of coping. Hence, nursing interventions directed at managing stress and improving coping should be used with mothers who use adaptation pattern 1. In particular, fathers should actively participate in parenting, and support their spouses.

• 대한간호학회지
• /
• 제26권4호
• /
• pp.917-929
• /
• 1996

The purpose of this study is to explore types of postpartum depression and to understand the nature and structure of the postpartum depression by using Q-methodological approach. As a way of research, 55 statements concerning postpartum depression were selected through individual interviews with postpartum mothers and literature review. 30 women were chosen as a subject group for the study, with opinions shown in 55 statements divided into 9 scales by forced distribution. PC QUANL Program was used for analysis and Q-factors were analyzed by using principal component analysis. As a result, postpartum depression experience was classified into 5 types. There are "Role-Strain Type", "Unattributional Depression Type", "Psychosomatic Symptoms Type", "Self-Compassion Type", and "Role-Crisis Type". Type I was named "Role-Strain Type", referring to the strain generally experienced by mothers with regard to the new role as a mother and as a social member. Type II was named "Unattributional Depression Type", referring to the symptom experienced by people who were in a state of vanity and a sense of loss. They often break into tears for no specific reasons. In case of Type III, people in a state of "Psychosomatic Symptoms Type" develop physical symptoms after suffering from inherent emotional conflict. Type IV was named "Self-Compassion Type" refers to the symptom shown by those who feel pity for their children and for themselves. And they show inability to cope with the reality properly. Type V was named "Role -Crisis Type", which is experienced by people who have a burden and a severe fear of their own job and their children in their mind, also showing serious conflict with maternal role. Futhermore, it was carried out to examine structure of postpartum depression in terms of degree of depression and adjustment ability. Type I showed mild degree of depression and relatively good adjustment ability. Type II showed broad range of degree in depression and moderate adjustment ability. Type III showed moderate depression and relatively low adjustment ability. Type IV revealed relatively serious degree of depression and the lowest adjustment ability. Type V revealed very serious degree of depression and the lowest adjustment ability. As a result, considering the structure of postpartum depression. Type I is considered to be a normal depression sympton which most mothers generally experience, followed by Type II, Type III, Type IV and Type V, each of which show increasingly worse degree of depression and lower adjustment ability. In conclusion, it seems to be it is necessary to understand distinct symptoms of postpartum depression and to examine the characteristics and structure of those types, so that it could lead to more individual nursing approach.cteristics and structure of those types, so that it could lead to more individual nursing approach.

• Child Health Nursing Research
• /
• 제6권2호
• /
• pp.224-239
• /
• 2000

This descriptive study was conducted to understand the contents and degree of parental stress level in the NICU patients, and to give a baseline data in developing nursing intervention program. Subjects were the 62 mother of hospitalized newborn in NICU of 1 University Hospital in Taejon City from May 1st, 1999 to November 30th, 1999, who agreed to take part in this study. The instrument used in this study were Parental Stressor Scales : NICU(PSS:NICU) developed by Miles et al. and validated by 3 NICU practitioners and 3 child health nursing faculties. The questionnaire has 4 dimensions and 45 items; sight and sounds of NICU(5 items), babies' appearance and behavior(19 items), parental role alteration and relationship with their baby(10 items), communication with health team(11 items). The questionnaire asks parents to rate each item on a five-point Likert type scale that ranges from (1) to (5). Total scores representing overall stress from the NICU environment are calculated by summing response to each item. A high score indicates high stress. A subscale score is calculated by summing the responses to each item in the subscale. Cronbach's α coefficients were .93. The data was analyzed as average, Frequency, Standard deviation, t-test, ANOVA, Pearson correlation coefficient by use of SPSS/PC+. The results of this study is summarized as follows ; 1. The total perceived stress level score of mothers was slightly high(3.6±.7). The highest scored dimension was 'appearance and behavior of the baby'(3.9±1.5), and next were 'relationship with their baby and parental role change'(3.5±1.4), 'communication with health team'(3.4±.9), 'sight and sounds of NICU'(3.2±.8). 2. Two variables were statistically significant with PSS:NICU total scale ; mother's perceived severity of the baby's condition (r=.482, P=.002) and mother's religious attendance(t=2.83, P=.01). The more the mother perceive their baby's condition severe, the higher the total stress score. There were high stress score noted in the mother of no religious attendance. 3. Four variables were statistically significant with NICU environment subscale ; mother's educational background(F=3.45, P=.04), religious attendance(t=2.28, P=.04), sex of the baby(t=2.83, P=.01) and NICU patients' hospital day(r=.359, P=.004). That is mother with high educational background and girl baby were high NICU environment subscale score. 4. Four variables were statistically significant with appearance and behavior of the baby subscale ; when first saw baby(F=3.52, P=.04), incubator care(t=2.83, P=.01), mother's perceived severity of the baby's condition(r=.303, P=.017), number of NICU visit(r=.441, P=.002). That is, seeing the baby first in the NICU and recieved incubator care was very stressful. Also, the more the mother perceive their baby's condition severe and more NICU visit, the higher the appearance and behavior of the baby subscale stress score. 5. Four variables were statistically significant with relationship with their baby and parental role change subscale ; when first saw baby(F=3.37, P=.04), sex of the baby(t=2.36, P=.03), incubator care(t=5.60, P=.00), mother's perceived severity of the baby's condition(r=.401, P=.001). That is, seeing the baby first in the NICU and girl baby was very stressful. Also, the more the mother perceive their baby's condition severe, the higher the relationship with their baby and parental role change subscale stress score. 6. Three variables were statistically significant with communication with health team subscale ; mother's educational background (F=3.63, P=.04), incubator care(t=4.24, P=.00), gestational age(r=-.394, P=.047), and birth weight(r=-.460, P=.004). That is, mother with high educational background and receiving incubator care were high communication with health team subscale score. Also, the shorter the gestational age and smaller the baby's birth weight, the higher the communication with health team subscale score. In conclusion, information about physical environment of NICU, the mother's perceived severity of baby's illness state, maternal role change related variables and the knowledge of characteristics of NICU patients must be included in nursing intervention program of mother's of NICU patients in reducing the maternal stress and anxiety level.

• 농업과학연구
• /
• 제43권1호
• /
• pp.52-60
• /
• 2016

In animal reproduction, the quality of oocytes and embryos has been evaluated by the expression of specific molecules. Follistatin (FST), which was isolated from follicular fluid, binds and bio-neutralizes the TGF-${\beta}$ superfamily members. Previous studies using the bovine model showed FST could be an important molecular determinant of embryo developmental competence. However, the effect of FST treatment on porcine embryo developmental competence has not been established. In this study, the effect of exogenous FST on porcine embryo developmental competence was investigated during in vitro culture. FST (10 ng/ml) treatment induced a significant decrease in the rate of cell arrest at the 4-cell stage. The expression levels of DNA-methyltransferase 1 (DNMT1), histone deacetylase 1 (HDAC1), and histone deacetylase 2 (HDAC2) were decreased in 4-cell stage embryos. FST treatment also resulted in significant improvements in developmental competence of embryos in terms of blastocyst formation rate and OCT-4 mRNA levels, the latter being related to pluripotency. In conclusion, during in vitro culture, FST treatment significantly ameliorated 4-cell block during embryonic development and improved embryo developmental competence. Therefore, FST treatment may potentially have a functional role in porcine embryogenesis that is broadly applicable to enhance in vitro embryo development.

• 한국보건간호학회지
• /
• 제7권1호
• /
• pp.1-16
• /
• 1993

The objective of this study is to review the role and function of the village health worker in the wake of the recent social changes in Korea. The stud}' also aimed at' elucidating' the characteristics of the village health worker organizations developed through community participation in this country. The study methods employed were: a review of literature and other existing information related to VHW's activities ; the use of Questionnaire and interview with VHW's on their activities in one selected county in 1992. The major findings obtained are as follows: 1. So far the community health care activities have been carried out by medical colleges, foreign aid agencies and religious organizations with a view to improving health care for the population in rural area. 2. The VHWs employed by the local community health services received remuneratiorin cash or in kind. However, presently no remuneration is paid to VHWs employed by the government village health projects. The training for VHWs is organized by County Health Center once a year for 1-2days regardless of pre-employment or refresher. 3. The needs of care for maternal and child health and family planning has been decline due to the decrease of the target population, but on the other hand, the needs of care by VHW for prevention of infectious diseases, health of the aging, management of geriatric diseases, prevention of poisoning of pesticides and environmental sanitation has beer increased. 4. It was felt strongly that the training for VHWs should be strengthened by means of developing a problem-solving oriented educational program in order to improve practical skills of VHWs.

• 한국발생생물학회지:발생과생식
• /
• 제22권3호
• /
• pp.263-273
• /
• 2018

Aquaporin (AQP) 3, a facilitated transporter of water and glycerol, expresses in placenta and fetal membranes, but the detailed localization and function of AQP3 in placenta remain unclear. To elucidate a role of AQP3 in placenta, we defined the expression and cellular localization of AQP3 in placenta and fetal membranes, and investigated the structural and functional differences between wild-type and AQP3 null mice. Gestational sacs were removed during mid-gestational period and amniotic fluid was aspirated for measurements of volume and composition. Fetuses with attached placenta and fetal membranes were weighed and processed for histological assessment. AQP3 strongly expressed in basolateral membrane of visceral yolk sac cells of fetal membrane, the syncytiotrophoblasts of the labyrinthine placenta and fetal nucleated red blood cell membrane. Mice lacking AQP3 did not exhibit a significant defect in differentiation of trophoblast stem cells and normal placentation. However, AQP3 null fetuses were smaller than their control litter mates in spite of a decrease in litter size. The total amniotic fluid volume per gestational sac was reduced, but the amniotic fluid-to-fetal weight ratio was increased in AQP3 null mice compared with wild-type mice. Glycerol, free fatty acid and triglyceride levels in amniotic fluid of AQP3 null mice were significantly reduced, whereas lactate level increased when compared to those of wild-type mice. These results suggest a role for AQP3 in supplying nutrients from yolk sac and maternal blood to developing fetus by facilitating transport of glycerol in addition to water, and its implication for the fetal growth in utero.