• The Journal of Pediatrics of Korean Medicine
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• v.26 no.1
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• pp.70-78
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• 2012

Objectives Recently, vitamin D supplements to breast-fed infants are being encouraged in Korea, and other countries. However, the reliability and validity assessment of supplements is insufficient. Therefore, this study suggests new Korean guidelines for vitamin D supplements of breast-fed infant. Methods The roles of Vitamin D for bone metabolism in children and the correlation between breast milk and Vitamin D were examined throughout domestic and international literature review. In addition, the efficacy and safety of vitamin D supplements were reviewed. Results Preventive effects of rickets by vitamin D supplementation remain unclear. Furthermore, concerns about the safety of vitamin D supplements intake have been raised. Korean guideline suggests breast-fed infants can get vitamin D through the skin safely, but maternal intake of vitamins through sunbath and diet is more effective and safe. Conclusions Limiting sunlight excessively and applying foreign countries' medical guideline for vitamin D supplements are not valid to apply as a domestic guideline for Korean breast-fed infants without considering ethnic and cultural characteristics.

• Neonatal Medicine
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• v.16 no.1
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• pp.89-93
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• 2009

Maternal diabetes is known to have teratogenic effects which increase the risk for congenital anomalies, such as caudal dysplasia, cardiac defects, hydronephrosis, and small left colon syndrome. Infants of diabetic mothers have a 10-fold higher frequency of anomalies in the central nervous system and a 5-fold higher frequency of congenital heart defects. However, jejunal atresia combined with multiple anomalies of the face, ears, and hands has rarely been reported. Herein we report a neonate born to a diabetic mother, who had hemifacial microsomia, displacement of the lacrimal ducts, polydactyly of the right hand, microtia of the right ear and proximal jejunal atresia presenting as bile regurgitation on the 1st day of life.

• Korean Journal of Community Nutrition
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• v.5 no.1
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• pp.120-129
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• 2000

Very little is known about the relation between isoflavone intake and menopausal symptoms in Korean woman To find the effects and correlations between these factors, questionnaires(maternal factors, menopausal symptoms) anthropometric measurement, 24hr dietary recalls, and urinary isoflavones analysis were conducted in 100 postmenopausal women residing in the Kyunggi-do rural area. The average age hight and weight of the subject were 61.5 years, 153.6 cm and 56.2kg. The average age at menarche, menopause, and menstrual cycle were 16.7 years, 47.2 years, 29.8 years, respectively. Most of the postmenopausal women experienced mildly menopausal symptoms. The mean calorie, protein and calcium intake were 1417.6 kcal(74.7% of the Korean RDA) 53.2 g(88.6% of the Korean RDA) and 454.0mg(65.6% of the Korean RDA) respectively. The ration of energy from carbohydrate, protein, and fat was 68: 15: 17 The average isoflavone intake from soy foods was 27.27 mg. The major food source of the isoflavone were soybeans and soybean curd. The average urinary isoflavone excretion was 2. 78nmol/mg Cr and showed significant positive correlation with isoflavone intake. Isoflavone intake from soy foods had a negative correlation with the severity of menopausal symptoms. Therefore, soy foods which contain isoflavone may have a protective effect on menopausal symptoms of women in Korea.

• Clinical and Experimental Pediatrics
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• v.54 no.2
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• pp.55-63
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• 2011

Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder that is caused by the lack of expression of paternally inherited imprinted genes on chromosome 15q11-q13. This syndrome has a characteristic phenotype including severe neonatal hypotonia, early-onset hyperphagia, development of morbid obesity, short stature, hypogonadism, learning disabilities, behavioral problems, and psychiatric problems. PWS is an example of a genetic condition caused by genomic imprinting. It can occur via 3 main mechanisms that lead to the absence of expression of paternally inherited genes in the 15q11.2-q13 region: paternal microdeletion, maternal uniparental disomy, and an imprinting defect. Over 99% of PWS cases can be diagnosed using DNA methylation analysis. Early diagnosis of PWS is important for effective long-term management. Growth hormone (GH) treatment improves the growth, physical phenotype, and body composition of patients with PWS. In recent years, GH treatment in infants has been shown to have beneficial effects on the growth and neurological development of patients diagnosed during infancy. There is a clear need for an integrated multidisciplinary approach to facilitate early diagnosis and optimize management to improve quality of life, prevent complications, and prolong life expectancy in patients with PWS.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.545-552
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• 2016

Background: The purpose of this study was to explore the effectiveness of a spiritual care training package in maternal caregivers of children with cancer. Materials and Methods: This study was a quasi-experimental study with pretest and posttest design consisting of a sample of 42 mothers of children diagnosed as having cancer. Participants were randomly assigned to either an experimental or a control group. The training package consisted of seven group training sessions offered in a children's hospital in Tehran. All mothers completed the Spirituality & Spiritual Care Rating Scale (SSCRS) and the Depression, Anxiety and Stress Scale (DASS-21) at pre and post test and after a three month follow up. Results: There was significant difference between anxiety and spiritual, religious, Personalized care and total scores spiritual care between the intervention and control groups at follow-up (P<0.001).There was no statistically significant difference in stress and depression scores between the intervention and the control groups at follow-up. Conclusions: Findings show that spiritual care training program promotes spirituality, personalized care, religiosity and spiritual care as well as decreasing anxiety in mothers of children with cancer and decreases anxiety. It may be concluded that spiritual care training could be used effectively in reducing distressful spiritual challenges in mothers of children with cancer.

• The Journal of Korean Society for School & Community Health Education
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• v.14 no.1
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• pp.37-47
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• 2013

Objectives: A descriptive correlational study was designed to examine the relationship of anger to psychosomatic symptoms. In addition, this study investigated the mediating effect of parental attachment in relation to anger and other variable. Methods: Data were collected from 112 subjects in grade 4 or 6, and descriptive statistics, Pearson correlation coefficient, and hierachical multiple regression were used with SPSS/PC 18.0 program to analyze the data. Results: There was a significantly positive effects between state-trait anger and psychosomatic symptoms. Father attachment negatively correlated state-trait anger and psychosomatic symptoms. Also, mother attachment negatively correlated state anger and psychosomatic symptoms. However, maternal attachment was not significantly associated with trait anger. Parental attachment had a significant mediating effect in relation to state-trait anger and psychosomatic symptoms. Conclusions: For the effective management of multi-cultural children's psychosomatic symptoms, programs including parental attachment increasing strategies should be established. These programs can increase parental attachment security which is mediator role between anger and psychosomatic symptoms.

• Molecules and Cells
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• v.25 no.2
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• pp.211-215
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• 2008

To gain a better understanding of the methylation imprinting changes associated with heat stress in early development, we used bisulfite sequencing and bisulfite restriction analysis to examine the DNA methylation status of imprinted genes in early embryos (blastocysts). The paternal imprinted genes, H19 and Igf-2r, had lower methylation levels in heat-stressed embryos than in control embryos, whereas the maternal imprinted genes, Peg3 and Peg1, had similar methylation pattern in heat-stressed embryos and in control embryos. Our results indicate that heat stress may induce aberrant methylation imprinting, which results in developmental failure of mouse embryos, and that the effects of heat shock on methylation imprinting may be gene-specific.

• Korean Journal of Child Studies
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• v.35 no.4
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• pp.103-122
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• 2014

The purpose of this study was to identify the variables affecting parenting efficacy of North Korean refugee mothers. The selected variables were marital satisfaction, social support, and acculturation. The participants consisted of 105 mothers who had defected from North Korea with preschool children living in Seoul, Gwangmyeong-si, and Gyeongsangnam-do provinces. The data thus collected were analyzed by descriptive statistics, t-tests, correlation, and multiple regression analysis. The results indicated that the marital satisfaction and social support had meaningfully positive effects on the parenting efficacy of North Korean refugee mothers. However, marginalization was found to be a predictor of competence-anxiety in parenting. The selected variables derived from the environmental systems in maternal parenting were significant factors in the parenting efficacy of North Korean refugee mothers and furthermore, their sociocultural environments were also important in parenting. These findings clearly showed that marital satisfaction and social support were the most significant variables of parenting efficacy of North Korean refugee mothers. The results of this study appear to have a great deal of utility as preliminary data to improve the parenting efficacy of North Korean refugee mothers.

• Korean Journal of Child Studies
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• v.34 no.2
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• pp.83-99
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• 2013

The premise underpinning this research is that cognitive evaluation is the starting point of children's emotional experience. It then went on to investigate how parents' person-oriented guidance affects children's emotional intelligence. Additionally, children's ego-resilience was analyzed as a variable that affects children's emotional intelligence and as a mediator between parents' person-oriented guidance and children's emotional intelligence. A purposive sampling was conducted in 4 elementary schools in metropolitan areas and made use of 466 students in 4th and 5th grade as research subjects. The results are summarized as follows：firstly, the more frequently parents used person-oriented guidance, the more children exhibited higher levels of ego-resilience and emotional intelligence. Secondly, vitality, peer relations, optimism, curiosity, emotional regulation, maternal person-oriented guidance were found to affect emotional intelligence in the order of relative significance of that influence. Thirdly, children's ego-resilience was found to intermediate parents' person-oriented guidance and children's emotional intelligence. In conclusion, individual children's evaluations of parental verbal stimuli was found to influence children's emotional intelligence, especially more significantly through the mediation of children's ego-resilience.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.6
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• pp.767-771
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• 2002

Breeding efficiencies were compared among three population schemes: a single population, a population with two subpopulations and a population with three sub-populations. A simulation experiment of selection was carried out for 10 generations with 20 replications each by comparing average breeding values and inbreeding coefficients among the three population schemes. Phenotypes of three traits were generated with a model comprising 36 loci, each with additive genetic effects and residuals distributed normally. Among the three population schemes, the single population scheme was definitely superior to the other two with regards to selection response and inbreeding. The multiple sub-population scheme was, however, considered to be an alternative population scheme when the difference in economic weights of the traits was small among the sub-populations, assuming moderate inbreeding depression for traits and crossbreeding. The scheme with two sub-populations had a higher genetic value than that with three subpopulations; however, the genetic values of the schemes were comparable when maternal heterosis was taken into account. The choice of population schemes may depend on the cost-sharing policy between the breeding population and the commercial population rather than just the breeding efficiency.