• Journal of the Korean Home Economics Association
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• v.43 no.12 s.214
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• pp.153-163
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• 2005

The purposes of this study were to investigate the differences of appearance behavior and ego integrity of elderly women according to demographic variables, and health, and to examine how the ego integrity of elderly women was influenced by appearance behavior, health, and demographic variables. The subjects were 117 elderly women(aged 60 to 70) in Jinju, Korea who were interviewed face-to face with a survey questionnaire. The results of the study were as follows. There were significant differences in appearance adornment and ego integrity (wise living and attitude toward life) according to age. After controlling for age, there were significant differences in appearance interest, makeup, and ego integrity according to education. There was a significant difference in ego integrity (attitude toward life) according to the presence of a spouse or mate. There were significant differences in appearance interest, makeup, and ego integrity according to health. Health and education had a significant effect on satisfaction with the present living. Health, age(-), and appearance behavior had a significant effect on wise living. Health, age(-), and education had a significant effect on attitude toward life. Education and health had a significant effect on appearance behavior. The present findings indicate that health state and appearance behavior, such as appearance interest and makeup, had a significant effect on the ego integrity of elderly women. On the whole, the ego integrity of elderly women was positively correlated with the level of health state, education, and appearance behavior.

• Journal of the Korean Chemical Society
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• v.52 no.1
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• pp.36-46
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• 2008

cyclization of primary arylselenocarboxylic amides with a-bromoketones afforded a variety of new 2,4-diaryl-1,3-selenazoles. Halogenation of the 2,4-diaryl-1,3-selenazoles with chlorine, bromine and iodine gave the new 1,1-dihalo-2,4-diaryl-1,3-selenazoles in good yields. Antiviral activity of some 1,1-dihalo-2,4-diaryl-1,3-selenazoles has been tested against AIDS virus (HIV-1 and HIV-2). They showed some bioactivity against HIV-1. All compounds were characterized by their elemental analysis, 1H NMR and mass spectroscopic data. The crystal structure of 2-(3,4-dimethoxyphenyl)-4-(4-bromophenyl)-1,3-selenazole displays the molecular configuration.

• Journal of Acupuncture Research
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• v.18 no.6
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• pp.53-58
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• 2001

Objective : The purpose of this study is to investigate the characteristics of patients with fracture admitted in oriental hospital. Methods : From october 1996 to october 2001, we retrospectively evaluated the simple radiographic proven 8441 patients with musculoskeletal pain in oriental hospital. The patients included 3899 men and 4542 women. All fractures were analyzed in terms of location, age and sex. Results : 1. The fracture rate of radiologic study was relatively high in foot, chest, upper extremity and hand. The frequent fractures were in spine (257 cases), foot (119 cases), upper extremity (83 cases). and chest (68 cases). 2. The male patients with fracture were significantly higher than female in 0-40 years group: in 0-20 years group(8.5 % vs 4.0 %, p<0.01), in 21-40 years group (4.1 % vs 2.6, p<0.05), while female patients with fracture were significantly higher than male patients in more than 60 years group( 10.1 % vs 15.4 %, p<0.01). 3. The incidence of fracture showed significant association with increased age except 0-20 years group(p<0.01). Spine and chest cage in mate, and upper extremity, pelvis, spine, ankle and chest cage in female were significantly higher on older age groups. Conclusion : The overall fracture rate of radiologic study was 6.6 % for patients with musculoskeletal problem admitted in oriental hospital. The distribution of fracture showed significant difference in terms of age, sex and site. So we believe the radiologic study is helpful to evaluate fracture in oriental hospital.

• Journal of The Korean Association For Science Education
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• v.5 no.1
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• pp.63-79
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• 1985

The purpose of our survey study was to investigate the status on perception and actual state toward science educational evaluation and objectives of middle school science teachers in Pusan. The perception and actual state were surveyed by the questionaire which was developed by Jong-Ok Woo et. al. We developed two kinds of questionaire. One is designed to use Likert type scale and is composed of two main category(SE; Science educational evaluation, SO; Science educational objectives) which contains 21 question items, and the other has 16 question items From 313 science teacger's responses of 75 middle schools in pusan, the tendency. of total(SE+SO) and each sub category, and the contrast with their background and actual state were analized by SPSS program of KAIST. Some results of our survey study can be summarized as follows; 1. Total tendency of science educational evaluation(SE) and objectives(SO) of middle school science teachers in pusan shows a positive and right tendency of conception in general(m-85.8/100). 2. Tendency of SE(m-87.8/100) are slightly higher than SO(m-81.7/100). At the level of 5% significance, there are correlated but shows low correlation (r=0.12(4). 3. In each correlation toward total tendency(SE+SO), SE is highly correlated(r-0.8486) but SO is moderately correlated(r=0.6297) at the level of 0.1% significance. 4. Tendencies of 5sub category (PE, PC, PD, PO, PB) shows considerably right tendencies (m=$73.4/100{\sim}92.7/100$), there are moderately correlated foward total tendency(SE+SO) at the level of 0.1% significance (r=$0.49{\sim}0.60$). 5. At the level of 5%significance, total means are no differences which their background(Sex, Final alma mate, Major, Difference of training), but there is differences to teaching career at the level of 5% significance.

• Journal of Applied Biological Chemistry
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• v.55 no.2
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• pp.95-101
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• 2012

Nutritional components of Ojuk leaf tea and Ojuk shoot tea prepared from the leaves and shoots of black bamboo (Phyllostachys nigra Munro) by tea manufacturing process were evaluated. In addition, the extraction yield of water soluble components from these teas in the general tea brewing condition (water extraction in $80^{\circ}C$ for 10 min.) and the contents of polyphenol and flavonoid were compared with not only the dried raw materials, but also green tea and mate tea. Finally, offline and online scavenging activities against 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) and di(phenyl)-(2,4,6 trinitrophenyl)iminoazanium free radicals were investigated to evaluate the antioxidant activity and explore the components showing ABTS free radical scavenging activity from tea infusion. These results demonstrated that these teas from black bamboo contain various nutritional components and can be used as traditional tea beneficial to human health.

• Resources Recycling
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• v.8 no.5
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• pp.51-58
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• 1999

The sbdy iwestlgaled ihc propa-ties of Lhe dust\ulcorner rrom fe~~oallomya ~~ufacturTeh. e chemical composition, cornpasitlon material, p d c l e sire md shapes of the bulk dust, sired dust and magnetically separated durl were mvesligaled. As the re\ulcornerulL, we suppose that the dust from &gh Carbon Fenama~~gunesMc anuiact~vingP rocess is not sufiicient as solulce material of Mn because of ale low Mn canlenl (13.5%) and complicaled composition mate~ial. The dust from Bug F!lter or AOD Proccss is mi~inlym ade up of 0.2-2 pm Mn30, (Hausmam~iu)p iutlde in spherical shape and thc Mn content is 63.190.The dust from Cooler of AOD Process is inninly made up of coarse Ca(O1-Or)zM. n,FeyO,, SiO, and fine Mn30d.

• Resources Recycling
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• v.8 no.5
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• pp.44-50
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• 1999

The sbdy iwestlgaled ihc propa-ties of Lhe dust\ulcorner rrom fe~~oallomya ~~ufacturTeh. e chemical composition, cornpasitlon material, p d c l e sire md shapes of the bulk dust, sired dust and magnetically separated durl were mvesligaled. As the re\ulcornerulL, we suppose that the dust from &gh Carbon Fenama~~gunesMc anuiact~vingP rocess is not sufiicient as solulce material of Mn because of ale low Mn canlenl (13.5%) and complicaled composition mate~ial. The dust from Bug F!lter or AOD Proccss is mi~inlym ade up of 0.2-2 pm Mn30, (Hausmam~iu)p iutlde in spherical shape and thc Mn content is 63.190.The dust from Cooler of AOD Process is inninly made up of coarse Ca(O1-Or)zM. n,FeyO,, SiO, and fine Mn30d.

• Proceedings of the Korea Water Resources Association Conference
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• 2012.05a
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• pp.930-930
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• 2012

최근 기후변화로 인하여 전 세계적으로 물 부족현상이 대두되고 있는 가운데 우리나라 또한 물 부족국가에 편재되어 있다. 더군다나 제주도는 최대 다우지임에도 불구하고 다른 타 지역과 마찬가지로 제주도 곳곳에서 물 부족 현상이 야기되고 있다. 이러한 현상은 제주도의 강우가 대부분 년 중 6월~9월에 집중되고, 그 기간 홍수유출 역시 경사가 급하고 15km 미만의 짧은 유로연장을 갖는 대부분의 하천의 특성상 홍수유출 지속시간이 단 시간에 불과하여 수자원 관리에 큰 어려움이 있기 때문으로 사료된다. 다만 일부하천의 경우 해안과 가까운 지점의 하상과 측벽에서 기저유출 성분인 용천수가 유출됨으로 1970년대부터 상수원으로 개발하여 일부분 이용되고 있다. 하지만 이 또한 정확한 용출량 산정이 어려워 수자원으로써의 활용이 미흡한 실정이다. 따라서 본 연구에서는 대상유역의 기저유출로 발생되는 용천수의 용출량을 산정하여 용천수의 이용 및 보전관리계획을 수립하는 중요한 척도를 제시함은 물론 제주 수자원의 대부분을 차지하는 지하수의 함양, 배출, 순환연구에 중요한 기초자료로 활용하기 위하여 진행되었다. 본 연구는 제주도 중서귀수역 주요 기저유출유역(강정천, 악근천)에 대하여 연구대상기간(2011.7~2011.12) 동안 하천의 유출량을 ADCP(Accoustic Doppler Current Profiler, SonTek사)와 전자기식 유속계(FLOW-MATE)를 이용하여 매월 2회 현장 계측을 실시하여 유출량 자료를 확보하였고, 일 단위의 모의가 가능한 유역단위의 준 분포형 장기 강우-유출 모델(continuous rainfall-runoff model)인 SWAT(Soil Water & Assessment Tool) 모델을 적용한 물수지 결과값과 비교 검정하여 제주도 기저유출 하천의 유출율 및 수문곡선의 특성을 분석하고 SWAT 모델을 통한 물수지 산정을 실시하였다. 중서귀수역의 기저유출 대상유역에 대한 지속적인 관측자료와 세계적인 SWAT모델을 이용한 정밀 수자원 해석결과는 서귀포시의 주 식수원으로 이용되고 있는 대상유역의 물순환 및 물수지분석과 통합 수자원의 연구진행, 향후 기후변화에 대비한 효율적인 수자원의 이용 및 확보를 위한 귀중한 자료로 이용될 수 있을 것으로 사료된다.

• Food Science and Biotechnology
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• v.27 no.6
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• pp.1843-1856
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• 2018

Tea is one of the most frequently consumed drinks due to its favourite taste and the health benefit. Tea is produced by several processes and drying is very important step to develop the flavour and destroys the enzymes in tea. However, during drying tea, polycyclic aromatic hydrocarbons some of which are carcinogen and genotoxin are naturally produced. The risk of PAHs by drinking tea was characterized by determining contents of 4 PAHs in tea. 4 PAHs including Benz(a)anthracene (BaA), Chrysene (CHR), Benzo(b)fluoranthene (BbF) and Benzo(a)pyrene (BaP) were investigated by GC-MS in total 468 tea products, which were contaminated up to $4.63ng\;g^{-1}$. Mate tea was the most highly contaminated by BaA, CHR, BbF and BaP and followed by Solomon's seal and Chrysanthemum. The Margin of Exposures calculated by the concentration of BaA, CHR, BbF and BaP and consumption amount of tea were higher than 10,000, and the risk of PAHs in tea were low concern to public health.

• Journal of Gastric Cancer
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• v.23 no.1
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• pp.207-223
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• 2023

Gastric cancer (GC) is the fourth leading cause of cancer-related deaths worldwide. Under the standard of care, patients with advanced GC (AGC) have a median survival time of approximately 12-15 months. With the emergence of immunotherapy as a key therapeutic strategy in medical oncology, relevant changes are expected in the systemic treatment of GC. In the phase III ATTRACTION-2 trial, nivolumab, a monoclonal anti-programmed cell death 1 (PD-1) antibody, as a third- or later-line treatment improved overall survival (OS) compared with placebo in patients with AGC. Furthermore, nivolumab in combination with 5-fluorouracil and platinum as a first-line treatment improved OS in patients with human epidermal growth factor receptor-2 (HER2)-negative AGC in the global phase III CheckMate-649 study. Another anti-PD-1 antibody, pembrolizumab, in combination with trastuzumab and cytotoxic chemotherapy as a first-line treatment, significantly improved the overall response rate in patients with HER2-positive AGC. Therefore, immune checkpoint inhibitors (ICIs) are essential components of the current treatment of GC. Subsequent treatments after ICI combination therapy, such as ICI rechallenge or combination therapy with agents having other modes of action, are being actively investigated to date. On the basis of the success of immunotherapy in the treatment of AGC, various clinical trials are underway to apply this therapeutic strategy in the perioperative and postoperative settings for patients with early GC. This review describes recent progress in immunotherapy and potential immunotherapy biomarkers for GC.