• Tuberculosis and Respiratory Diseases
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• 제72권1호
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• pp.68-71
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• 2012

Untreated massive hemoptysis, especially in patients with tuberculous-destroyed lung, is a serious complication resulting in considerable morbidity and mortality. We report a case of a patient who had active tuberculosis and a destroyed left lung with massive bleeding. He was transferred to our clinic with intubation of a right-sided Robertshaw double lumen tube and right upper lobe collapse likely due to tube malposition that was presented on chest X-ray. Because hemoptysis had persisted after bronchial arterial embolizaton, we replaced the double lumen tube with a conventional endotracheal tube and inserted an endobronchial blocker into the left main bronchus through an endotracheal tube guided by bronchoscopy to prevent aspiration of blood into the right lung. Left pneumonectomy was performed and hemotpysis was ceased. We suggest that the use of an endobronchial blocker followed by surgery may be a safe and effective modality of treatment in patients with persistent bleeding after bronchial arterial embolization.

• 대한두개안면성형외과학회지
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• 제17권1호
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• pp.28-30
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• 2016

Major maxillofacial bone injury itself can be life threatening from both cardiovascular point of view, as well as airway obstruction. Significant hemorrhage from facial fracture is an uncommon occurrence, and there is little in the literature to guide the management of these patients. We report a 73-year-old male driver who was transported to our hospital after a motor vehicle collision. The patient was hypotensive and tachycardic at presentation and required active fluid resuscitation and transfusion. The patient was intubated to protect the airway. All external attempts to control the bleeding, from packing to fracture reduction, were unsuccessful. Emergency angiogram revealed the bleeding to originate from terminal branches of the sphenopalatine artery, which were embolized. This was associated with cessation of bleeding and stabilization of vital signs. Despite the age and severity of injury, the patient recovered well and was discharged home at 3 months with full employment. In facial trauma patients with intractable bleeding, transcatheter arterial embolization should be considered early in the course of management to decrease mortality rate.

• 한국해양공학회지
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• 제17권2호
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• pp.8-13
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• 2003

Soil, ground water, and sea bed are exposed to a continuous accumulation of polluted materials, causing serious environmental damage. It has been reported that such pollution causes a massive mortality of fish stock in rivers due to the resuspension of toxic chemicals, occurring during strong wind conditions. Therefore, it becomes apparent that there is an immediate demand for the restoration treatment of polluted river bed (or sea bed) sediment layers. Pollution levels of major rivers and ports, such as Paldang, Kyungan rivers, and Masan port, are becoming of great public concern, and are posing a serious environmental threat. In particular, the pollution of the Shi-hwa river has become a nation wide issue for the last few years. In spite of such public concern, the pollution levels of such rivers or ports are worsening everyday. In this study, an environmentally sound engineering package is introduced that helps to restore the polluted river bed or sea bed sediments. This engineering package consists of a suction facility, followed by a series of mechanical, chemical, and biological treatment units. The suction facility is designed to minimize secondary pollution that occurs from the resuspension of toxic materials during suction. The sea bed cleaning engineering package is designed to be installed on the top of a floating barge. Such a combination of environmental plant and shipbuilding technology provides a cost-effective solution, minimizing the transportation between suction and treatment facilities.

• Journal of Microbiology and Biotechnology
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• 제11권3호
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• pp.394-398
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• 2001

Because of the great concern over the possibility of contamination from the rod-shaped nuclear virus (PRDV) from Japan and white spot virus (WSSV) from Taiwan, most eggs used in Korean shrimp farms are currently obtained from local broodstock. In addition, the screening of imported broodstock for any viral presence at the National Fisheries Research and Development Institute is also mandatory. Nonetheless, massive mortality from white spot syndrome continues in Korea. In the present study, we present an improved PCR method to use tissue-extracted DNA instead of viral DNA extracted from a purified virus based on a sucrose density gradient, and produced results within 8 h. In 1998, this modified PCR method was able to detect that diseased Penaeus japonicus were infected within 8 h. In 1998, this modified PCR method was able to detect that diseased Penaeus japonicus were infected only with PRDV, while Fenneropenaeus chinensis were infected with both PRDV and WSSV. In 1999, PRDV and WSSV were detected in F. chinensis with signs of infection, but not with WSSV alone.

• Mycobiology
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• 제38권4호
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• pp.229-237
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• 2010

Members of the genus Aspergillus are the most common fungi and all reproduce asexually by forming long chains of conidiospores (or conidia). The impact of various Aspergillus species on humans ranges from beneficial to harmful. For example, several species including Aspergillus oryzae and Aspergillus niger are used in industry for enzyme production and food processing. In contrast, Aspergillus flavus produce the most potent naturally present carcinogen aflatoxins, which contaminate various plant- and animal-based foods. Importantly, the opportunistic human pathogen Aspergillus fumigatus has become the most prevalent airborne fungal pathogen in developed countries, causing invasive aspergillosis in immunocompromised patients with a high mortality rate. A. fumigatus produces a massive number of small hydrophobic conidia as the primarymeans of dispersal, survival, genome-protection, and infecting hosts. Large-scale genome-wide expression studies can now be conducted due to completion of A. fumigatus genome sequencing. However, genomics becomes more powerful and informative when combined with genetics. We have been investigating the mechanisms underlying the regulation of asexual development (conidiation) and gliotoxin biosynthesis in A. fumigatus, primarily focusing on a characterization of key developmental regulators identified in the model fungus Aspergillus nidulans. In this review, I will summarize our current understanding of how conidiation in two aspergilli is regulated.

• Journal of Chest Surgery
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• 제43권4호
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• pp.433-436
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• 2010

폐절제후 발생하는 급성폐동맥색전증은 매우 드물지만 높은 사망률을 보인다. 이는 폐절제후 발생하는 가장 위험한 합병증 중에 하나이다. 폐엽절제 후 아무런 합병증 없이 회복 중이던 환자에서 갑자기 발생한 급성폐동맥색전증으로 보존적 치료에도 악화되어 응급 색전제거술로 치료하여 좋은 결과를 얻었기에 문헌 고찰과 함께 발표하는 바이다.

• 한국가금학회지
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• 제30권1호
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• pp.55-59
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• 2003

경기도 소재 산란종계 농장에서 심한 운동실조와 급격한 폐사율 증가 등의 임상증상이 발현되어 국립수의과학검역원 조류질병과에 38주령 닭 15수가 질병진단을 목적으로 의뢰되어 병리해부검사, 조직검사, 임상병리 검사를 실시한 결과 아래와 같은 결과를 얻을 수 있었다. 각 1만수씩 입식된 3개 계군의 폐사율은 17.7％(A동), 12.3％(B동), 21.1％(C동)이었으며 폐사 직전 닭들의 특이적인 임상증상으로는 침울, 식욕결핍, 다리마비, 기립불능 등이 관찰되었다. 병리해부검사상에서는 대퇴부와 다리부위 골격근의 변성과 괴사로 변색, 긴장도 상실, 연화 등이 확인되었다. 조직검사 결과 근섬유의 괴사와 함께 심한 염증세포의 침윤이 특징적인 괴사성 근증이 관찰되었다. 또한 혈청내 creatine kinase, asparte aminotransferase, akaline phosphatase 농도검사에서도 정상적인 조류의 범위보다 2배 이상 상승된 농도가 확인되어 간접적으로 괴사성 근증임을 확인할 수 있었다.

• Journal of Chest Surgery
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• 제41권4호
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• pp.520-522
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• 2008

원발성 대동맥-식도 누공은 드문 질환으로 식도 내로 대량의 출혈을 일으키는 치명적인 질환이다. 원인으로는 흉부 대동맥류가 가장 흔하며, 암에 의한 궤양, 염증 등이 있다. 수술이 근치적 치료 방법이지만 유병률과 사망률이 높으며, 최근에는 스텐트-그라프트를 이용한 비수술적 치료 방법이 소개되고 있다. 저자들은 수술을 통해 누공을 박리하고 식도와 대동맥을 일차 봉합하여 치료한 원발성 대동맥-식도 누공 1예를 문헌 고찰과 함께 보고한다.

• Journal of Chest Surgery
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• 제21권2호
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• pp.307-315
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• 1988

A clinical analysis was performed on 97 cases of chest injuries experienced at Department of Thoracic and cardiovascular Surgery, Armed Forces Capital Hospital during 2 years period from 1986 to 1988. Of 97 patients of chest trauma, 39 cases were result from penetrating injuries whereas 58 cases were from non-penetrating injuries, and there were 77 cases of hemothorax and / or pneumothorax, 47 of rib fracture, 8 of foreign body, 6 scapular and clavicle fracture, 5 of diaphragmatic injuries, 4 of paraplegia. The majority of chest injuries were encounted in the age group between 21 and 30 years-old, mean age was 25.9 years-old and all cases were male except one. Gun-shot wound was the most common cause in the penetrating injuries and the majority of non-penetrating chest injury patients were traffic accident and fist or kick accounted for next. The principles of therapy for chest trauma were rapid expansion of the lung by closed thoracostomy[45 cases] and thoracentesis only[3 cases] but thoracotomy done at 27 cases because of massive bleeding or intrapleural hematoma, foreign body, cardiac injury, diaphragmatic injury and bronchial rupture. The over-all mortality was 2.07 percent[2 cases among all], a case was from penetrating injuries and another was from non-penetrating injuries.

• Journal of Chest Surgery
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• 제15권4호
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• pp.422-427
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• 1982

A clinical analysis of 82 cases who were sustained the penetrating gun-shot wound in the chest by 8 bullets was done during 4~ year-period from January 1978 to August 1982 in the department of thoracic surgery, CA FGH. Among 82 cases, 61 cases [74.4%] of them were brought to the Hospital by ambulance, 21 cases [25.6%] were by Helicopter and 76 cases [92.7%] of them were admitted within 4 hours after wounding. Thirty eight [46.3%] patients were treated by closed thoracotomy only, 19 cases [23.2%]by open thoracotomy, 18 cases [22.0%] by primary closure with debridement, and 7 cases [8.5%] by vascular surgery. Causes of open thoracotomy were due to massive intrapleural bleeding in 16 cases, rupture of diaphragm in 2 Gases, and heart injury in one case. Among 25 cases of surgical complications, wound infection was most common in 16 cases [53.5%] and recurrent pneumothorax in 3 cases [10%], empyema in 3 cases [10%], and BPF in one case [3.3%]. Hospital mortality was seen in 6 cases due to hypovolemic shock and respiratory insufficiency in 4 cases, spinal shock in 2 cases due to spinal injury.