• Title/Summary/Keyword: Mass regression

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The Response of Parenchymal Mass and Airway Obstruction from Lung Cancer to Radiation Therapy (단순 흉부 X-선 사진상 폐암 소견에 대한 방사선 치료의 효과 -단기 추적 조사를 중심으로-)

  • Kang, Cheol-Hoon;Shin, Sei-One;Kim, Myung-Se
    • Radiation Oncology Journal
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    • v.7 no.2
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    • pp.227-233
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    • 1989
  • From April 1986 to Dec 1988, fifty one patients with carcinoma of lung were treated by radiation therapy in Department of Therapeutic Radiology, Yeungnam University Hospital Of the 51 patients, $31(61\%)$ were squamous cell ca, $8(15.7\%)$ were small cell ca, and remained $4(7.9\%)$ were other cell types. Total radiation dose was average $64Gy (60\~75 Gy)$ for group A and 45Gy $(40\~59Gy)$ for group B. The mass regression and the response of airway obstruction to radiation therapy was established on the basis of follow up chest X-ray. The mass regression above $50\%$ of total volume was noted in 23 patients $(74.2\%)$ among 31 patients and the difference between two groups was not seen. In squamous cell ca, however, the mass regression rate (above $50\%$ of total volume) was $83.3\%$ (10/12) in group A compared to $50\%$ (3/6) in group B(p<0.05). The alleviation of airway obstruction was noted as follows. In group A, CR $42.9\%$, PR $35.7\%$, no response $21.4\%$ and in group B, CR $55.6\%,\;PR\;33.3\%$, no response $11.1\%$. But, in squamous cell ca, responsiveness is higher than group B. The study indicates that the importance of higher radiation dose in the management of primary tumor mass and airway obstruction caused by lung cancer especially squamous cell ca. So, meticulous treatment planning and multimodality combination therapy without increasing si.do elect or complication is recommended in management of inoperable bronchogenic carcinoma.

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Prediction of Quantitative Traits Using Common Genetic Variants: Application to Body Mass Index

  • Bae, Sunghwan;Choi, Sungkyoung;Kim, Sung Min;Park, Taesung
    • Genomics & Informatics
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    • v.14 no.4
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    • pp.149-159
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    • 2016
  • With the success of the genome-wide association studies (GWASs), many candidate loci for complex human diseases have been reported in the GWAS catalog. Recently, many disease prediction models based on penalized regression or statistical learning methods were proposed using candidate causal variants from significant single-nucleotide polymorphisms of GWASs. However, there have been only a few systematic studies comparing existing methods. In this study, we first constructed risk prediction models, such as stepwise linear regression (SLR), least absolute shrinkage and selection operator (LASSO), and Elastic-Net (EN), using a GWAS chip and GWAS catalog. We then compared the prediction accuracy by calculating the mean square error (MSE) value on data from the Korea Association Resource (KARE) with body mass index. Our results show that SLR provides a smaller MSE value than the other methods, while the numbers of selected variables in each model were similar.

A Study on Combustion Characteristic with Mass Flux of Solid fuel in Single Port Hybrid Rocket (Single Port 하이브리드 로켓에서의 고체연료 질량유속을 고려한 연소특성 연구)

  • Lee Jung-Pyo;Kim Soo-Jong;Lee Seung-Chul;Kim Jin-Kon
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2006.05a
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    • pp.246-250
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    • 2006
  • In general, combustion characteristic of hybrid propulsion was shown with the regression rate depending on only massflow rate of oxidizer But this empirical relation was not represented well effect of the thermo-chemical properties of solid fuel. So, in this study, the combustion characteristics was studied with the mass transfer number(B number) of solid fuel instead of regression rate with various fuel. The PMMA, PP, and PE were used as fuel, and gas oxygen as oxidizer in this experiment. The mass flowrate of gas oxigen was controlled by the several chocked orifices that have different diameter, and the oxidizer supply range was $3.66\sim45.3g/sec$. As result, the empirical relation for mass flux of solid fuel was obtained with mass transfer number, and mass flux of oxidizer as follow; $\dot{m}^{'}_f\;=\;0.0175G^{0.55}B^{0.4}$.

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A Study on the Combustion Properties of Single-Port Hybrid propulsion System with Various Fuel (Single port 하이브리드 추진 시스템의 연료에 따른 연소특성 연구)

  • You Woo-Jun;Kim Jin-Kon;Lee Jung-Pyo;Kim Soo-Jong;Lee Seung-Chul;Kuk Tae-Seung
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2005.11a
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    • pp.368-372
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    • 2005
  • The variation of regression rate of single port hybrid rocket was studied with various fuel. As fuel, PE, PMMA were used and gas oxygen as oxidizer. The regression rate depends on but flow rates of oxidizer also thermodynamic properties of fuel. In this study, the empirical relation for regression rate of solid fuel were found with mass transfer coefficient(B number) and oxidizer flow rate.

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A Study on the Transient Combustion Characteristic in PE-GOX Hybrid Rocket (PE-GOX 하이브리드 로켓에서의 과도 연소 특성 연구)

  • Cho, Sung-Bong;Lee, Jung-Pyo;Song, Na-Young;Kim, Soo-Jong;Kim, Jin-Kon
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2006.11a
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    • pp.228-231
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    • 2006
  • In general, burning time is not considered with a factor of an empirical relation on the combustion characteristic in hybrid propulsion system. So, The effect of burning time on hybrid combustion characteristics and propulsion characteristics was studied. As results, regression rate is decrease with burning time, but fuel mass flux is maintained nearly constant with burning time at given oxidizer mass flux.

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A Study on Regression Rate in End-Burning Hybrid rocket with Variation of Swirl Intensity (End-Burning 하이브리드 로켓의 스월 강도 변화에 따른 연료 후퇴율에 관한 연구)

  • Choi, Won-Jun;Woo, Kyoung-Jin;Moon, Hee-Jang;Sung, Hong-Gye;Kim, Jin-Kon
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2012.05a
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    • pp.70-75
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    • 2012
  • In this paper, the regression rate of the End-Burning Hybrid Rocket with variation of swirl intensity was investigated experimentally with the variation of fuel diameter, injector shape and angle. When fuel grain diameter is large, fuel mass flow rate increases. And the injector diameter increase, fuel regression rate decrease. The impinging effect of oxidizer flow on fuel surface for fuel combustion efficiency is stronger than swril effect in this End-burning propulsion system. The relation between the regression rate, oxidizer mass flux and swirl intensity was obtained.

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Thermal conductivity prediction model for compacted bentonites considering temperature variations

  • Yoon, Seok;Kim, Min-Jun;Park, Seunghun;Kim, Geon-Young
    • Nuclear Engineering and Technology
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    • v.53 no.10
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    • pp.3359-3366
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    • 2021
  • An engineered barrier system (EBS) for the deep geological disposal of high-level radioactive waste (HLW) is composed of a disposal canister, buffer material, gap-filling material, and backfill material. As the buffer fills the empty space between the disposal canisters and the near-field rock mass, heat energy from the canisters is released to the surrounding buffer material. It is vital that this heat energy is rapidly dissipated to the near-field rock mass, and thus the thermal conductivity of the buffer is a key parameter to consider when evaluating the safety of the overall disposal system. Therefore, to take into consideration the sizeable amount of heat being released from such canisters, this study investigated the thermal conductivity of Korean compacted bentonites and its variation within a temperature range of 25 ℃ to 80-90 ℃. As a result, thermal conductivity increased by 5-20% as the temperature increased. Furthermore, temperature had a greater effect under higher degrees of saturation and a lower impact under higher dry densities. This study also conducted a regression analysis with 147 sets of data to estimate the thermal conductivity of the compacted bentonite considering the initial dry density, water content, and variations in temperature. Furthermore, the Kriging method was adopted to establish an uncertainty metamodel of thermal conductivity to verify the regression model. The R2 value of the regression model was 0.925, and the regression model and metamodel showed similar results.

A Study of Efficient Rock Mass Rating for Tunnel Using Multivariate Analysis (다변량분석을 이용한 터널에서의 효율적인 암반분류에 관한 연구)

  • Wye, Yong-Gon;No, Sang-Lim;Yoon, Ji-Son
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.2 no.2
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    • pp.41-49
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    • 2000
  • Rock Mass Rating has been widely applied to the underground tunnel excavation and many other practical problems in rock engineering. However, Rock Mass Rating is hard, even by the experts of tunnel assessment owing to lack of investigation system. In this study, using multivariate analysis we presented rock mass rating system that is objective and easy to use. The constituents of RMR are decided to RQD, condition of discontinuities, groundwater conditions, intact rock strength, orientation of discontinuities, spacing of discontinuities in important order. In each step, we proposed the best multiple regression model for RMR system.

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A Study on Combustion Characteristics of End-Burning Hybrid Propulsion System with the Various Fuel (End-burning 하이브리드 추진시스템의 연료에 따른 연소특성 연구)

  • Lee Seung-Chul;Kim Jin-Kon;Kim Soo-Jong;You Woo-Jun;Lee Jung-Pyo
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2005.11a
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    • pp.323-326
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    • 2005
  • In this study, experimental studies were performed the combustion characteristics of end- burning hybrid propulsion system. PMMA, PE were used as fuel and gas oxygen as oxidizer. The regression rate depend on oxidizer flow rate also on thermodynamic properties of fuel. as result, empirical formula for regression rate was deduces with oxidizer flow rate and mass transfer coefficient B number.

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Factors Associated with Body Mass Index (BMI) and Physical Activity among Korean Juveniles

  • Jeong, Chankyo;Song, Jong-Kook
    • Korean Journal of Exercise Nutrition
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    • v.14 no.2
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    • pp.81-86
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    • 2010
  • The purpose of this study was to identify the factors associated with child's Body Mass Index (BMI) and physical activity. The participants (n = 133) were Korean juveniles (3rd and 4th graders) and their parents. They completed a questionnaire packet including the SPARK (Sports, Play, and Active Recreation for Kids) survey and the parent equivalent survey. Correlation, multiple linear regression and binary logistic regression analyses were applied to identify the association between child's BMI and 10 factors of SPARK as predict or variables. 25.6% of the participants were classified as overweight (21.1%) or obesity (4.5%). 3 parental factors including mother's BMI and frequency of mother's and father's physical activity were identified as significant predictors of children's BMI. The 10 variables accounted for 28% of the variance (p<.01) in the linear regression model. These results provide insight into parental factors which are related to a child's BMI and physical activity. Parental role modeling which refers to parents' efforts to model an active lifestyle for children plays an important role.