• Title/Summary/Keyword: Margin of Safety

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Hand Exposure of Operator to Chlorpyrifos during Mixing/loading and Risk Assessment (유기인계 살충제 Chlorpyrifos 유제 살포액 조제 시 농작업자의 손 노출량 측정 및 위해성 평가)

  • Kim, Eunhye;Lee, Hyeri;Jeong, Mihye;Hong, Soonsung;Kim, Jeong-Han
    • The Korean Journal of Pesticide Science
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    • v.16 no.4
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    • pp.391-394
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    • 2012
  • Exposure and risk assessment during mixing/loading of chlorpyrifos emulsifiable concentrate (EC, 20%) were carried out. Limit of detection and limit of quantitation were 0.02 and 0.1 ng, respectively. Calibration curve linearity and reproducibility were excellent. Recovery of chlorpyrifos from gloves was 72.3-103.4%. During mixing/loading procedure, average hand exposure amount of chlorpyrifos was 3.9 mg which is corresponding to 0.004% of total active ingredient in the prepared spray mixture. In calculation of MOS (Margin of Safety) for risk assessment, male Korean average body weight and AOEL (Acceptable Operator Exposure Level) were used. Nine events of mixing/loading procedure were assumed per day. And 75 percentile of 30 repetition (4.6 mg) was used as for the worst case. MOS was more than 1 for total repetition, indicating mixing/loading work was of least risk. However, MOS of individual repetition was examined, two cases were less than 1 suggesting careful work habit is essential in mixing/loading procedure.

Analysis of Benzo[a]pyrene Content and Risk Assessment (훈제식육식품 중 벤조피렌 함량 분석 및 안전성 평가)

  • Cho, Hyoun-Kyoung;Kim, Mee-Hye;Park, Sung-Kug;Shin, Han-Seung
    • Food Science of Animal Resources
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    • v.31 no.6
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    • pp.960-965
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    • 2011
  • The content of benzo[a]pyrene from 69 smoked meat products commonly consumed in Korean food market was analysed with high performance liquid chromatography. Smoked meat products including smoked chicken, pork, turkey and duck were saponified, extracted and cleaned up to analyze the benzo[a]pyrene content. As a result of analysis from smoked meat products, the mean benzo[a]pyrene content was 0.42 ${\mu}g$/kg and the highest content of benzo[a]pyrene was 2.87 ${\mu}g$/kg detected in smoked chicken product. All somked meat products contained benzo[a]pyrene below the limit regulated by Korean Food and Drug Administration (KFDA). Exposure assessment of benzo[a]pyrene from smoked meat products ingestion was calculated by using National Health and Nutrition Survey (NHNS). The estimated lifetime average daily intake of benzo[a]pyrene was 0.187 ng/kg bw/d. Margin of exposure of benzo[a]pyrene was ranged from 1,657,754 to 3,957,219.

A Study on the Flexural Minimum Reinforcement for Prevention of Brittle Failure Specified in KCI and EN Codes (유럽과 국내기준에 규정된 취성파괴 방지를 위한 휨 최소철근량 고찰)

  • Park, Sung-Jae;Kang, Tae-Sung;Moon, Do-Young
    • Journal of the Korea Concrete Institute
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    • v.26 no.2
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    • pp.211-218
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    • 2014
  • In the design of reinforced rectangular concrete beam structure, the minimum amount of flexural reinforcement is required to avoid brittle failure. KCI code is based on concept of ultimate strength and usually used as a model code. But bridge design code enacted by Ministry of land, transportation and maritime affairs in 2012 is based on concept of limit state and similar to Euro code EN 1992-2. This means that the minimum reinforcement presented in both design codes has different origination and safety margin. When rectangular concrete beams with minimum reinforcement are designed according to EN and KCI codes, the amount of minimum reinforcement specified in EN code is only 76% of that in KCI code. This makes the design engineers to be confused. In this study, flexural tests were conducted on nine beams with the two different minimum reinforcement specified in KCI and EN design codes. In results, the measured ratios of nominal strength to crack strength from the test were about 25% greater than those evaluated from the equations presented in KCI and EN codes. The EN beams having only 76% of the minimum reinforcement for the KCI beams were fractured by rupture of steel reinforcement but in ductile manner. It is confirmed that the minimum reinforcement concrete beams designed according to both codes have enough safety margin in flexural capacity and moreover in ductility.

Case Study on Reliability Analysis of Offshore Wind Turbine Foundation (해상풍력기초 신뢰성해석 사례분석 연구)

  • Yoon, Gillim;Kim, Hongyeon
    • Journal of the Korean GEO-environmental Society
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    • v.13 no.12
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    • pp.91-98
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    • 2012
  • In this paper, the behavior of offshore wind turbine(OWT) foundation which is modeled by using existing design method and FEM is compared. When the same type of foundation is designed under the same sea and ground condition, the behavior characteristics with each model are compared. As a result, the member forces between apparent fixity and distributed spring type foundation which consider the ground stiffness are not different markedly, while fixed-base type foundation shows relatively lower member forces, which results in smaller safety margin. In other words, considering ground stiffness is reasonable because soil-pile interaction affects significantly on the analysis result. A case study with a monopile shows significant errors between p-y and FEM model at the head and tip of the pile. Also, it shows that the errors at the tip with diameter increase of the pile is larger. Thus, considering ground characteristics and engineering judgment are necessary in practice. A comparison of reliability analysis between tripod and monopile type foundation on the same condition shows larger probability of failure in monopile type and it indicates that the safety margin of monopile type can be lower.

A Study on the Establishment of Allowable Criteria for Sailing Ships at Offshore Wind Farms (해상풍력발전단지해역 선박 통항 허용기준 설정에 관한 연구)

  • Ohn, Sung-Wook;Lee, Chang-Hyun;Kim, Cheol-Seong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.7
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    • pp.841-847
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    • 2018
  • Since global energy consumption and demand for energy have dramatically risen, a focus on environmental problems and sustainability has become more important. Clean and renewable energy sources such as offshore wind power generation have received attention among new renewable energy options as alternative energy resources. Due to maintenance and operational perspectives, offshore wind farms have been planned for installation in many coastal waters. However, development of offshore wind farms faces interference from existing maritime traffic along the planned areas. In order to safely and effectively govern marine traffic in the vicinity of wind farms and inner areas, standard criteria are suggested to allow vessels to sail the internal waters of offshore wind farm areas. Therefore, the purpose of this study is to establish allowable criteria for sailing vessels and safety zones for offshore wind farms by investigating the local regulations of various offshore wind farm cases overseas. The commended inner safety zone of wind farms is proposed to be a distance of 150 % of the rotation diameter of the wind turbine rotor and a distance of 200 m from the outer wind turbine for the outer safety zone. Besides this, the allowable criteria for sailing vessels within a wind farm is proposed to have an air draft of 14.47 m south-west wind farm sea areas for a minimum margin to avoid hull contact through evaluation of the tide and height of a wind turbine. further studies will be needed to establish vessel sailing criteria among adjacent offshore wind farms as well as vessel sailing criteria within a single offshore wind farm.

Analysis of Exposure Characteristics and Exposure Rating of Participants with Injuries from CMIT/MIT Humidifier Disinfectants (CMIT/MIT 가습기살균제 사용에 따른 피해구제 신청자의 노출등급 및 노출특성 분석)

  • Gihong Min;Junghyun Shin;Eun-Kyung Jo;Seula Lee;Jihun Shin;Dongjun Kim;Jaemin Woo;Yoon-Hyeong Choi;Wonho Yang
    • Journal of Environmental Health Sciences
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    • v.49 no.3
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    • pp.169-177
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    • 2023
  • Background: The Korea Centers for Disease Control and Prevention (KCDC) has identified cases of people suspected of suffering lung disease potentially caused by chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) used in humidifier disinfectants (HDs). The Korean Ministry of Environment (MoE) epidemiological investigation and toxicity test study found that HDs caused health damage such as asthma and lung disease. Objectives: The main purposes of this study were to classify the HD exposure rating and to analyze the exposure characteristics that affect exposure to CMIT/MIT HDs. Methods: The exposure characteristics and socio-demographic characteristics of victim participants using CMIT/MIT HDs were investigated through questionnaires. An inhalation no observed adverse effect level (NOAEL) for CMIT/MIT was produced based on inhalation toxicity values. Exposure ratings (class 1~class 2) were cross-tabulated with clinical ratings (acceptable~unacceptable). A correlation analysis was conducted with the main exposure characteristics that affect the exposure concentration of CMIT/MIT HDs. Results: The concentration in indoor air of CMIT/MIT was 8.75±25.40 ㎍/m3, and the exposure concentration was 2.30±6.29 ㎍/m3. The CMIT/MIT exposure rating of 67 participants with high exposures of not more than MOE 100 were evaluated as 14.5%, while the damage participants who matched the clinical rating made up 4.5%. The exposure concentration of CMIT/MIT showed a positive correlation with the daily usage amount and usage frequency, and a negative correlation with volume of the indoor environment. Conclusions: A new exposure rating could be suggested and calculated based on the MOE, and the factors affecting the exposure concentration could be identified.

Analysis about relation of Won/Dollar Foreign Exchange Rate and Interest Rate of Korea (한국 원/달러환율과 금리의 관계분석)

  • 김종권
    • Proceedings of the Safety Management and Science Conference
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    • 2002.11a
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    • pp.305-319
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    • 2002
  • International capital movement has made progress at global liberalization of finance and foreign exchange, international monetary norm changing into floating exchange rate system, easiness of collection of information and trade at improvement of information communication technology from early of 1970's. Results of empirical test for relation between foreign exchange rate or various determination factors of foreign exchange rate and interest rate are followed by next sentences. First, according to relation between foreign exchange rate and interest rate, correlation for each of variables after OECD entrance is increased. But, long-term &short-term interest rate is affected by Hanbo & Kia's bankruptcy, continuous large scale coporates bankruptcy and crisis of foreign exchange. Therefore, financial instability is occured. If portfolio investment fund has been inflow as it is mollified by continuous shortage of foreign exchange and fall of country's credit rating, it is expected to have positive effect for long-term & short-term interest rate from appreciation of won against dollar. Second, results from relation between determination factor of foreign exchange rate and interest rate are followed by next sentences. If surplus of current account and goods account is continued, yield of corporate bond is to be stable. But, margin of surplus is expected to diminish after second quarter 98, and difference between external and domestic interest (after adjusting foreign exchange rate) is to be diminished. And if net inflows of foreign investor's fund (stock and bond) is diminished, it is to have negative effect for yield of corporate bond. According to foreign investor's investment movement of previous years, hedge md were stayed at least during two years in Mexico. It means that sudden capital outflow is not to be happened at Korea. But if external factors from depreciation of yen and China's renminbi are instable, interest rate is expected to increase from capital's outflows. Third, if it is to decrease instability of foreign exchange rate from increase in surplus of future current account, credit rating's upwardness, stability of yen and renminbi, foreign exchange rate is expected to be stable. It is expected to have continuous stability from short-term interest rate to long-term interest rate in this empirical test.

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Coil-Protected Technique for Liquid Embolization in Neurovascular Malformations

  • Keun Young Park;Jin Woo Kim;Byung Moon Kim;Dong Joon Kim;Joonho Chung;Chang Ki Jang;Jun-Hwee Kim
    • Korean Journal of Radiology
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    • v.20 no.8
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    • pp.1285-1292
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    • 2019
  • Objective: To evaluate the safety and efficacy of the coil-protected technique for liquid embolization in neurovascular malformations. Materials and Methods: Twenty-two patients who underwent coil-protected liquid embolization for symptomatic cranial (n = 13) and spinal (n = 9) arteriovenous fistula (AVF) or arteriovenous malformations (AVMs) were identified. A total of 36 target feeder vessels were embolized with N-butyl cyanoacrylate and/or Onyx (Medtronic). This technique was used to promote delivery of a sufficient amount of liquid embolic agent into the target shunt or nidus in cases where tortuous feeding arteries preclude a microcatheter wedging techniqu and/or to prevent reflux of the liquid embolic agent in cases with a short safety margin. The procedure was considered technically successful if the target lesion was sufficiently filled with liquid embolic agent without unintentional reflux. Angiographic and clinical outcomes were retrospectively evaluated. Results: Technical success was achieved for all 36 target feeders. Post-embolization angiographies revealed complete occlusion in 16 patients and near-complete and partial occlusion in three patients each. There were no treatment-related complications. Of the six patients who showed near-complete or partial occlusion, five received additional treatments: two received stereotactic radiosurgery for cerebral AVM, two underwent surgical removal of cerebral AVM, and one underwent additional embolization by direct puncture for a mandibular AVM. Finally, all patients showed complete (n = 19) or near-complete (n = 3) occlusion of the target AVF or AVM on follow-up angiographies. The presenting neurological symptoms improved completely in 15 patients (68.2%) and partially in seven patients (31.8%). Conclusion: The coil-protected technique is a safe and effective method for liquid embolization, especially in patients with various neurovascular shunts or malformations who could not be successfully treated with conventional techniques.

Analysis about relation of Won/Dollar Foreign Exchange Rate and Interest Rate of Korea (IMF 전후기간의 원/달러환율과 금리에 대한 실증분석)

  • Kim, Jong-Gwon
    • Proceedings of the Safety Management and Science Conference
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    • 2005.11a
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    • pp.569-579
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    • 2005
  • International capital movement has made progress at global liberalization of finance and foreign exchange, international monetary norm changing into floating exchange rate system, easiness of collection of information and trade at improvement of information communication technology from early of 1970's. Results of empirical test for relation between foreign exchange rate or various determination factors of foreign exchange rate and interest rate are followed by next sentences. First, according to relation between foreign exchange rate and interest rate, correlation for each of variables after OECD entrance is increased. 'But, long-term & short-term interest rate is affected by Hanbo & Kia's bankruptcy, continuous large scale coporates bankruptcy and crisis of foreign exchange. Therefore, financial instability is occured. If portfolio investment fund has been inflow as it is mollified by continuous shortage of foreign exchange and fall of country's credit rating, it is expected to have positive effect for long-term & short-term interest rate from appreciation of won against dollar. Second, results from relation between determination factor of foreign exchange rate and interest rate are followed by next sentences. If surplus of current account and goods account is continued, yield of corporate bond is to be stable. But, margin of surplus is expected to diminish after second quarter 98, and difference between external and domestic interest (after adjusting foreign exchange rate) is to be diminished. And if net inflows of foreign investor's fund (stock and bond) is diminished, it is to have negative effect for yield of corporate bond. According to foreign investor's investment movement of previous years, hedge fund were stayed at least during two years in Mexico. It means that sudden capital outflow is not to be happened at Korea.

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Probabilistic Analysis of Failure of Soil Slopes during Earthquakes (지진시 사면파괴의 확률론적 해석)

  • 김영수;정성관
    • Geotechnical Engineering
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    • v.5 no.1
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    • pp.27-34
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    • 1989
  • This study presents a probabilistic analysis of the stability of homogeneous soil slopes during earthquakes. The stability of the slope is measured through its probability of failure rather than the customary factor of safety. The maximum horizontal ground acceleration is deterimined with Donovan and McGuire equation. The earthquake magnitude (m) is a random variable the Probability density function f(m) has been obtained with a use of Richter law. The potential failure surfaces are taken to be of an exponential shape (log-spiral) , Uncertainties of the shear strength parameters along potential failure surface are expressed by one-dimensional random field model. From a first order analysis the mean and variance of safety margin is osculated. The dependence on significant seismic parameters of the probability of failure of the slope is examined and the results are presented in a number of graphs and tables. On the base of the results obtained in this study, it is concluled that (1) the present model is useful in assessing the reliability of soil slopes under both static and seismic conditions: and (2) the probability of failure of a soil slope is greatly affected by the values of the seismic parameters that are associated with it.

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