• Asian Pacific Journal of Cancer Prevention
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• v.14 no.3
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• pp.1601-1607
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• 2013

A determination of circulating tumor cell (CTC) effectiveness for prediction of progression-free survival (PFS) and overall survival (OS) was conducted as an adjunct to standard treatment of care in breast cancer management. Between November 2008 and March 2009, 22 metastatic and 12 early stage breast carcinoma patients, admitted to Ankara Oncology Training and Research Hospital, were included in this prospective trial. Patients' characteristics, treatment schedules and survival data were evaluated. CTC was detected twice by CellSearch method before and 9-12 weeks after the initiation of chemotherapy. A cut-off value equal or greater than 5 cells per 7.5 ml blood sample was considered positive. All patients were female. Median ages were 48.0 (range: 29-65) and 52.5 (range: 35-66) in early stage and metastatic subgroups, respectively. CTC was positive in 3 (13.6%) patients before chemotherapy and 6 (27.3%) patients during chemotherapy in the metastatic subgroup whereas positive in only one patient in the early stage subgroup before and during chemotherapy. The median follow-up was 22.0 (range: 21-23) and 19.0 (range: 5-23) months in the early stage and metastatic groups, respectively. In the metastatic group, both median PFS and OS were significantly shorter in any time CTC positive patients compared to CTC negative patients (PFS: 4.0 vs 14.0 months, Log-Rank p=0.013; and OS: 8.0 months vs. 20.5 months, Log-Rank p<0.001). OS was affected from multiple visceral metastatic sites (p=0.055) and higher grade (p=0.044) besides CTC positivity (log rank p<0.001). Radiological response of chemotherapy was also correlated with better survival (p<0.001). As a result, CTC positivity was confirmed as a prospective marker even in a small patient population, in this single center study. Measurement of CTC by CellSearch method in metastatic breast carcinoma cases may allow indications of early risk of relapse or death with even as few as two measurements during a chemotherapy program, but this finding should be confirmed with prospective trials in larger study populations.

• Journal of the Korean Association of Geographic Information Studies
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• v.22 no.4
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• pp.158-168
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• 2019

Korea Hydrographic and Oceanographic Agency(KHOA) carried out a research project named 'Marine Fisheries Infrastructure Construction and Technology Training for the Philippines' as part of the 1st Official Development Assistance(ODA) from 2015 to 2018. It is preparing for the 2nd ODA project which will begin in 2020. Besides, recently, the Philippines is paying attention to marine territory management and response capability due to problems such as the sea-level rise and coastal erosion caused by climate change. Therefore, before 2nd ODA to the Philippines, this study analyzed the vertical ocean model on the vertical datum in Korea and suggests the direction of development of the vertical ocean modeling system for the vertical datum in the Philippines using the observed data from the permanent tide station which was built by the Philippines ODA research project over the last four years. Moreover, as a pilot study, the Sulu Sea in the Philippines was selected and analyzed by harmonic analysis method. At each tide station, constants for correction had been computed. And the grid-based tidal model was constructed based on this study. As a result of the study, similar tidal characteristic were observed when the prediction and the measured tide were compared by applying the constants for correction between two station in the sea area with similar tidal level. These results could be used as basic data for the 2nd ODA to the Philippines, and contributed to construct and maintain a close cooperation and friendship between Korea and the Philippines.

• Journal of Digital Convergence
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• v.11 no.4
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• pp.331-338
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• 2013

For this research, 27 out of 52 patients with chronic low back pain involving sacroiliac joint pain were classified into the experimental group to conduct pelvic exercise program and traditional physical therapies in parallel, and the remaining 25 ones were classified into the control group to only apply traditional physical therapies for 6 weeks. After that, their clinical samples were randomly extracted. Before the experiment, both of the experimental group and the control group had the Oswestry disability index test to see how big their pain was and their hip joint angles were analyzed during walking. After the post-test, finally, the results of the Oswestry disability index test and hip joint angles while walking before and after the experiment were compared between two groups to know the effect of pelvic stability exercise program. Within-group results and between-group results both displayed significantly reduced low back pain, and when comparing hip joint angles of the experimental group, there were differences between mid stance phase, terminal stance phase, pre swing phase and early swing phase of the right hip joint, and mid stance phase, terminal stance phase, pre swing phase and early swing phase of the left hip joint. In the control group, there were significant differences between mid stance phase, terminal stance phase and early swing phase of the right hip joint, and loading response phase, mid stance phase, terminal stance phase and pre swing phase of the left hip joint. as a result, pelvic stability exercise program is helpful to gait rhythm on stance phase and swing phase although effective to decrease Oswestry disability index including pain.

• Journal of Digital Convergence
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• v.15 no.10
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• pp.339-348
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• 2017

This study was conducted to examine the differences of anger expression style and cognitive characteristics among adolescents depending on the level of game addiction and game engagement. 420 high school boys were administered the Game Addiction/Engagement Scale, Behavioral Anger Response Questionnaire to measure anger expression style, and Irrational Belief Scale to measure cognitive characteristics. The results of correlation analyses showed that addiction had positive correlations with all the irrational belief factors and behavior anger factors except for assertion and avoidance. Engagement was positively correlated with all the variables except for direct anger-out, avoidance, and self-downing. Participants were divided into three groups depending on the level of addiction and engagement. Addiction high risk-low engagement group showed the lowest scores on support-seeking and the highest scores on diffusion and self-downing. Addiction high risk-high engagement group showed the highest scores on direct anger-out. Based on these findings, it was suggested that counselling strategies for adolescents at high risk of game addiction need to be varied depending on the level of game engagement.

• Journal of the East Asian Society of Dietary Life
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• v.19 no.2
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• pp.157-168
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• 2009

The principal objective of this study was to provide basic data regarding health care services for middle-aged men, via an analysis of the relationships among stress level, food habits and well-being-related attitudes with social-demographic characteristics and health-related factors. The main findings of this study were as follows. The average age of the participants was $48.7{\pm}5.2$. With regard to health status, 18.8% of the participants were diagnosed with digestive diseases within the past year. Stress levels were higher in the participants with lower levels of educational attainment. Furthermore, participants who had become divorced or lived separately from their families, participants who did not have their own houses, and participants who reported low marital satisfaction also had high levels of stress. Our food habits scores revealed meaningful differences among the study subjects, and were shown to vary with marital satisfaction, occupation, and residence type. In terms of both the importance and practice level of well-being-associated food habits, the most frequent response in this study was 'Consume home-made food rather than processed or ready-to-eat food' ($4.30{\pm}0.86$, $3.68{\pm}1.04$). In terms of importance level, the factors most relevant to well-being in terms of food habits were education level, marital satisfaction, residence type, self-assessed health status, smoking, drinking, regular exercises and leisure activities. With regard to practice levels, the degree to which subjects engaged in food habits targeted toward well-being differed meaningfully depending on marital status, marital satisfaction, residence type, family type, self-assessed health status, smoking, drinking, nutritional supplement intake, regular exercises and leisure activities. After analyzing the correlation among stress level, food habit score and the attitude towards well-being-related dietary habits (importance and practice level), we observed a meaningful relationship between the four factors at the level of p<0.001. According to the above result, continuous attention to health, including the appropriate control of smoking and drinking, as well as, stress management, via regular exercises and appropriate food habits is expected to exert a positive influence on the prevention of disease, and is also expected to improve quality of life. For all well-being-associated items, the importance level was shown to be higher than the practice level. Thus, in order to foster health-oriented food habits, we recommend that a new plan be designed, targeted toward ease of active practice for middle-aged men.

• Journal of Environmental Health Sciences
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• v.43 no.3
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• pp.223-232
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• 2017

Objectives: In response to increased interest in the safety of children's products, a risk management system is being prepared through exposure assessment of hazardous chemicals. To estimate exposure levels, risk assessors are using deterministic and probabilistic approaches to statistical methodology and a commercialized Monte Carlo simulation based on tools (MCTool) to efficiently support calculation of the probability density functions. This study was conducted to analyze and discuss the usage patterns and problems associated with the results of these two approaches and MCTools used in the case of probabilistic approaches by reviewing research reports related to exposure assessment for children's products. Methods: We collected six research reports on exposure and risk assessment of children's products and summarized the deterministic results and corresponding underlying distributions for exposure dose and concentration results estimated through deterministic and probabilistic approaches. We focused on mechanisms and differences in the MCTools used for decision making with probabilistic distributions to validate the simulation adequacy in detail. Results: The estimation results of exposure dose and concentration from the deterministic approaches were 0.19-3.98 times higher than the results from the probabilistic approach. For the probabilistic approach, the use of lognormal, Student's T, and Weibull distributions had the highest frequency as underlying distributions of the input parameters. However, we could not examine the reasons for the selection of each distribution because of the absence of test-statistics. In addition, there were some cases estimating the discrete probability distribution model as the underlying distribution for continuous variables, such as weight. To find the cause of abnormal simulations, we applied two MCTools used for all reports and described the improper usage routes of MCTools. Conclusions: For transparent and realistic exposure assessment, it is necessary to 1) establish standardized guidelines for the proper use of the two statistical approaches, including notes by MCTool and 2) consider the development of a new software tool with proper configurations and features specialized for risk assessment. Such guidelines and software will make exposure assessment more user-friendly, consistent, and rapid in the future.

• Journal of the Korean Association of Geographic Information Studies
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• v.20 no.1
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• pp.85-97
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• 2017

In recent years, the damage scales of water disasters such as typhoons, tsunamis, and heavy snow have been increasing globally as a result of global warming and climate changes. In particular, the economic loss caused by typhoons has been increasing for overpopulated areas that have undergone economic development and urbanization since the 1960s. In this study, we investigated and analyzed satellite images captured before and after typhoons on the Korean peninsula, including Typhoon Chaba (2016), Typhoon Rusa ('02), and Typhoon Maemi ('03). There was a limitation in utilizing existing satellites. Domestic satellites have mostly been developed and operated for the observation of the weather, ocean, and topography, as well as for use in communication. There are therefore insufficient temporal and spatial observations for water management and disaster response. In this work, we expanded the scope to overseas satellites and collected data from GMS, TRMM, COMS, and GPM. In the future, it will be necessary to develop and launch water resources satellites that can provide sufficient temporal and spatial data analysis units to obtain rapid and accurate water hazard information for the Korean peninsula.

• Journal of The Korean Association of Information Education
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• v.12 no.2
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• pp.183-194
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• 2008

This research was conducted from the perspective of student management focusing on such central topic as realization of research ethics on the basis of research ethics case study model. In this study, improvement method for research ethics education through means of application of DEVAC System, which is a paper plagiarism detection system, and survey on current status of research ethics in college education and degree of consciousness thereof were explored. Through these investigations, a topic relating to establishment of the foundation in order to foster consciousness of research ethics in the college education was established as the primary purpose of this study. To accomplish the purpose of this study, firstly, actual situation of paper plagiarism committed by the college students and their consciousness were surveyed. Secondly, the research ethics education was examined through means of applying DEVAC paper plagiarism detection system. The results from investigations revealed the followings: First, 424 students (65.43%) who participated in this research and survey on the fact of paper plagiarism had experience of report plagiarism, and the result of investigation showed that 49.3% of students among those who had experience of paper plagiarism committed report plagiarism more than three times in a semester. And, 34.1% of participants showed a positive response to the use of a paper plagiarism detection system in the college, and results from the investigation displayed that the creative education (39.0%) marked the highest scores as in the educational method to reinforce the research ethics. Second, the results from examination of paper plagiarism having applied DEVAC system indicated that use of this system can be an alternative to prevent paper plagiarism from students. It is realized through this study that there is a necessity in various respects to build up the foundation which will enable individual students to improve their consciousness to such a degree so as to make them clearly recognize the fact that plagiarism is criminal act.

• Journal of Agricultural Extension & Community Development
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• v.20 no.2
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• pp.407-429
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• 2013

Although rural areas account for more than 80% of the total land area of South Korea, most of them are deteriorated and living environment is inconvenient. In addition, the migration of young generation to urban areas and ageing have reduced the population and caused not only cavitation phenomena of villages but also stagnant communities. As for one of the rural areas, the seat of Myeon Office located in Oesan-myeon, Buyeo-gun, Chungcheongnam-do, this study presented not a plan only for strengthening hub functions but the methodology of the complex development plan in consideration of the regional characteristics in the comprehensive improvement project in seat of Myeon Office. From the perspective of enhancing the function of the seat of Myeon Office, it is inevitable to establish plans based on hardware. However, empowerment of the residents in the targeted areas also works as an important factor. In other words, each project promoted by the plan will be mainly operated by the local residents. Therefore, it is necessary to establish a management system of this. The success or failure of the established plan is based on the accurate survey of the issues of the targeted areas and demand, and this depends on participation and positive response of the residents of the targeted areas. That is, the method as a 'local community network' is required in order to increase the effect of resident participation in the planning area.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.05a
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• pp.294-297
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• 2015

Recently, big data analysis which is based on machine learning has been gained a lot of attentions in various fields. Especially, agriculture is considered as one promising field that machine learning algorithm can be efficiently utilized and accordingly, lots of works have been done so far. However, most of the researches are focusing on the forecast of weather or analysis of genome, and machine learning algorithm for livestock management, especially which uses individual data of livestocks, e.g., temperature and movement, are not properly investigated yet. In this work, we propose fast abnormal livestock detection algorithm based on machine learning, more specifically expectation maximization, such that livestock which has problem can be efficiently and promptly found. In our proposed scheme, livestocks are divided into two clusters using expectation maximization based on their bionic data and the abnormal livestock can be detected by comparing the size of two clusters. Especially, we divide the case in which single livestock has problem and the case in which livestocks have epidemic such that fast response is enabled when epidemic case. Moreover, our algorithm does not need statistical information.