• Journal of Veterinary Clinics
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• v.39 no.1
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• pp.23-27
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• 2022

An 11-year-old spayed female Maltese dog presented with mass in oral cavity. On conscious oral examination, the right maxillary canine tooth was not visible, and a lesion has been suspected of mass existed in canine tooth area. The adjacent maxillary first premolar was buried in the lesion, with a little part of the tooth exceptions. On radiographic examination, the canine tooth was buried horizontally in the lesion, and the root part was adjacent to the first premolar tooth. Extraction was performed for a treatment. When the lesion was incised, the canine tooth was horizontal with the concave surface facing the palatal, and formed double teeth by fusing with the premolar tooth at the roots parts of the teeth. This report described the double teeth in the dentigerous cyst rarely reported in dogs.

• Korean Journal of Veterinary Research
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• v.63 no.2
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• pp.8.1-8.3
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• 2023

A 13-year-old neutered male Maltese dog presented to our hospital with lethargy and anorexia. Laboratory abnormalities included severe non-regenerative anemia (hematocrit, 12.9%; reticulocyte count 12.8 K/µL). The cytology of bone marrow revealed erythroid hypercellularity with mild myelofibrosis. Therefore, late-stage precursor-targeted immune-mediated anemia (PIMA) was diagnosed. Multimodal treatment including 2 immunosuppressant drugs (prednisolone and mycophenolate mofetil), antithrombic drug (clopidogrel), and blood transfusion was performed. The dog showed complete remission from PIMA, and the total duration of follow-up was 622 days. This is the first case report of canine PIMA managed successfully with prednisolone and mycophenolate mofetil in Korea.

• Journal of Veterinary Clinics
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• v.25 no.2
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• pp.126-130
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• 2008

A six year-old male Maltese dog was presented to the Konkuk University Veterinary Teaching Hospital (KUVTH) with mass in right scapula region. Physical examination, radiography, magnetic resonance imaging (MRI), complete blood count (CBC), serum biochemistry, cytological analysis of fine needle aspiration and histopathological examination were performed. There was no remarkable finding in CBC. Alkaline phosphatase (ALP) was found to be increased in serum chemistry profile. Osteolysis was seen on radiographs of the scapula. MRI revealed mixed signal intensity in scapula. Cytological examination of fine-needle aspirate (FNA) was suggestive of sarcoma. We confirmed that the neoplastic cells were fibrosarcoma by immunohistochemical and Masson's trichrome staining.

• Korean Journal of Veterinary Research
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• v.45 no.2
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• pp.251-254
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• 2005

An 11-year-old, 3.3 kg, male Maltese dog was referred to Veterinary Teaching Hospital of Konkuk University because of diarrhea and severe anemia. Abnormal physical examination findings included left submandibular lymph node enlargement, pale mucous membrane, cataract, and bloody diarrhea. Results of hematologic examination revealed a marked lymphocytosis resulting in leukocytosis and the markedly increased numbers of small, well-differentiated lymphocytes in the peripheral blood. Serum biochemical abnormalities consisted of elevated AST and ALP, hyperphosphatemia, hypoglycemia, and hypoalbuminemia. Radiographic examination showed cardiomegaly and hepatosplenomegaly. Results of urinalysis included bilirubinuria and proteinuria. Based on results of examination described above, chronic lymphocytic leukemia was diagnosed. Chemotherapy was initiated with cyclophosphamide ($300mg/m^2$, IV once every 2 weeks), vincristine ($0.75mg/m^2$, IV once every 2 weeks, alternating weeks with the cyclophosphamide), and plus prednisolone ($50mg/m^2$, PO, SID for a week, then $20mg/m^2$, PO every other day). The response to chemotherapy was partially present. This study first demonstrates clinicopathological findings and chemotherapeutic response of chronic lymphocytic leukemia in Korea.

• Journal of Veterinary Clinics
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• v.33 no.6
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• pp.381-384
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• 2016

A 7-year-old intact female Maltese dog was referred to the hospital with a history of paresis in the hind limbs, left head turn, and a loss of balance that persisted for 2 weeks. Her condition was initially managed with steroids, prescribed by the referring veterinarian, but her neurological symptoms were not alleviated. Physical and neurological examinations, radiography, computed tomography, and magnetic resonance imaging were performed. Based on the findings on these examinations, caudal occipital malformation syndrome (COMS) with syringohydromyelia was diagnosed. Medical treatment was not effective in the previous trial; therefore, foramen magnum decompression, durotomy, and free autogenous adipose tissue grafting were performed. After 3 days, an improvement was observed in the clinical symptoms and was maintained for 8 months postoperatively. Based on the results, it is suggested that the decompression method with a fat graft may be considered an effective surgical treatment for the management of COMS that did not respond well to previous medical treatment.

• Journal of Veterinary Clinics
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• v.24 no.4
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• pp.522-528
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• 2007

A 3-year-old male Maltese dog(weighing 2.5 kg) was referred with an excessive movement of mandible and depression. Comprehensive diagnostic investigation revealed an end-stage of renal disease with secondary hyperparathyroidism. The renal allograft was performed after the condition of dog was stabilized by hemodialysis and medical treatment. After transplantation, the renal function of this dog was returned to normal. thereafter, the dog died suddenly without apparent clinical signs. The subsequent pathological studies revealed the actual etiology of death was not clearly identified However acute pancreatitis caused by abrupt introduction of food after prolonged luting might be involved in the etiology. This case study showed the necessity of pancreatic function test in postoperative management after renal transplantation.

• Journal of Veterinary Clinics
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• v.34 no.4
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• pp.283-286
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• 2017

A 4-month-old, female Maltese dog was referred with continuous heart murmur. Patent ductus arteriosus was diagnosed via radiography and echocardiography. The patient was untreated because of client's refusal. After 13 months, the dog was referred again with seizure and salivation. Laboratory examination revealed increased liver enzymes, hyperammonemia and decreased total cholesterol and total protein. Microhepatica was identified on abdominal radiography. CT angiography showed a shunt vessel that originated from the portal trunk to the prehepatic caudal vena cava and patent ductus arteriosus connecting proximal descending aorta with the main pulmonary artery. No portal vasculature toward liver is observed after shunt vessel. The patient was diagnosed as concurrent patent ductus arteriosus and congenital extrahepatic portosystemic shunt with suspected portal vein aplasia. In human, cardiac malformations are frequently observed in patients with congenital extrahepatic portosystemic shunt with portal vein aplasia. This report described concurrent patent ductus arteriosus and congenital extrahepatic portosystemic shunt with suspected portal vein aplasia in a dog.

• Korean Journal of Veterinary Service
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• v.39 no.3
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• pp.193-197
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• 2016

A 12-years-old Maltese (castrated male) dog with jaundice and purulent discharge from the shoulder was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. A physical and laboratory examination revealed that the mucosa of the conjunctiva and the sclera were icteric, and the liver functional enzyme level and the total bilirubin level were increased. Duodenal caudal deviation caused by suspected masses in diameter of about 2 cm was shown by radiographic and ultrasonographic examinations. Using fine needle aspiration (FNA) and computed tomography (CT), the dog was diagnosed with alimentary lymphoma. The dog was treated with chemotherapy. Hematuria was discovered and dysuria occurred because of sterile hemorrhagic cystitis, which is a unique complication resulting from the use of cyclophosphamide.

• Journal of Veterinary Clinics
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• v.38 no.5
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• pp.231-234
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• 2021

A 14-month-old, intact female Maltese (case 1) and a 26-month-old, spayed female Dachshund (case 2) had persistent regurgitation over 1 year and 2 years, respectively. In both cases, there were not specific findings in blood examination. Diagnostic imaging and fluoroscopy revealed that gastroesophageal reflux (GER) occurred when the patients ate a barium meal without abdominal contraction. They were treated with proton-pump inhibitor (esomeprazole), sucralfate and prokinetics (cisapride) while in a standing position for an hour after every meal, according to the gastroesophageal disease (GERD) suggested treatment. The case 1 dog was discharged with improved clinical signs, and the case 2 dog also had been improved clinical signs; however, aspiration pneumonia occurred in case 2, which was thought to be a complication from GERD. After receiving treatment for aspiration pneumonia, the case 2 dog was discharged from the hospital. Since there was no further improvement in symptoms after discharge, the case 1 dog was euthanized by owner's request, and the case 2 is alive, having only mild clinical signs upon the writing of this paper.

• Journal of Veterinary Clinics
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• v.15 no.2
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• pp.464-467
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• 1998

In 5-year male m811ese, was showed aggressive bebavior, $1.5{\times}1.0 cm$ mobile mass that was located in right iinguinal area was unilaterally palpated, and the dog was appeared no pain. In the ultrasonography, there was a 41.26{\times}119 cm$ oval hypo-echogenic mass. In the histopathohgic examination, testicular hypoplasia was observed but there was not any evidence of development of neoplasia. In bilateral cryptorchidectomy, descended testis near the left side of prepuce was incised and the retained testis directly incised and eliminated by closed method. After operation, there was a good prognosis without hemorrage and inflammation.