• 한국임상수의학회지
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• 제36권3호
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• pp.176-179
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• 2019

A giant prostatic urethral calculus has not been previously reported in dogs and should be distinguished from prostatic calculus. A 7-year-old castrated male Maltese dog with a 2-month history of relapsing hematuria and urinary incontinence with slowly progressing paraphimosis was referred. On abdominal radiography and ultrasonography, there was a giant calculus in the region of prostate or urethra, one left ureteral calculus, one urinary bladder calculus, and two penile urethral calculi. On computed tomography for evaluating the accurate location and planning the surgical approach, the giant calculus was located at the prostatic urethra. The calculi in urinary bladder, prostatic and penile urethra were surgically removed. These calculi were mixed-type of calcium oxalate monohydrate, struvite and calcium phosphate carbonate. On the basis of the urolith analysis and urine bacterial culture results, antibiotics and prescription diet were adjusted. At the 3-month follow-up, there were no clinical sings but paraphimosis was still remained, and ultrasonography revealed newly-formed, small urethral calculi at the prostatic urethra. This is the first report to describe the case of a canine giant prostatic urethral calculus and its clinical signs, diagnostic imaging findings, treatment, and outcome. CT may be useful to assess the accurate location and surgical approach for such calculi.

• 한국임상수의학회지
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• 제36권3호
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• pp.180-183
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• 2019

A 7-year-old, male Maltese dog with a body weight of 2.8 kg was presented with a history of hind limbs ataxia that progressed to tetraparesis over a one-month period. Based on physical and neurological examinations, tetraparesis with concomitant UMN signs, kyphosis and severe neck pain were identified. On MRI scan, we tentatively diagnosed this patient as a primary intramedullary spinal cord tumor. Therapy with lomustine plus hydroxyurea and prednisolone was initiated and the clinical signs rapidly improved. The patient was regularly checked by MRI scan and the range of the mass was gradually reduced to complete remission for 11 months. About 19 months after treatment, the patient showed anemia and hematochezia which suspected as adverse effects of chemotherapy. The condition was getting worse over 2 months and the patient suddenly expired 657 days after initial presentation. On histopathological examination, the spinal cord sample was identified as a neuronal atrophy without evidence of tumor cell.

• 한국임상수의학회지
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• 제30권5호
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• pp.359-362
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• 2013

6살령의 중성화된 숫컷 말티즈(4.16 kg)가 2일전 스켈링과 발치를 실시한 후 지속적인 구강내 출혈로 본원에 내원하였다. 환축은 폰 빌레브란트 인자 항원 평가 결과 54% (정상 범위 70%에서 180%)였으며, 유전된 폰 빌레브란트병를 가진 동형접합체로 판정되었다. 초기 치료를 위해 신선 전혈 수혈을 실시하였다. 수혈 후 환축은 임상증상이 개선되었으며 현재까지 건강한 상태이다. 본 증례는 한국내 말티즈에서 발생한 제 1형 폰 빌레브란트병의 첫 번째 진단 보고이다.

• 한국임상수의학회지
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• 제23권3호
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• pp.337-339
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• 2006

4년령의 중성화된 암컷 말티즈 견이 급성으로 발병하고 4일 동안 지속된 진신 진전 우측으로의 사경 수평성 안구진탕, 그리고 약간의 보행실조에 대한 평가를 위해 내원하였다. 환견은 의식이 뚜렷하고 외부자극에 잘 반응하였다. 신경계 검사 상에서 양안의 수평성-, 위치성 안구진탕 그리고 약간의 보행실조가 나타났다. 또한 양안의 위협반사가 소실된 상태였다. 중등도의 전신 긴장성 진전이 사지와 두부에서 특이적으로 관찰되었다. 혈액검사, 방사선, 그리고 자기공명영상에서 이상소견이 관찰되지 않았다. 뇌척수액의 세포학적 검사를 통해 약간의 비화농성 염증 소견을 확인하였다. 이와 같이 염증성 그리고 특발성의 특징을 가지고 있었기 때문에 스테로이드 반응성 진전 증후군이 강하게 의심되었다. 환견은 면역억제 용량으로 투여된 코르티코스테로이드에 매우 잘 반응하였다. 따라서 진전을 유발하는 다른 원인들을 배제하고, 임상증상 및 치료에 대한 반응에 근거하여 스테로이드 반응성 진전 증후군으로 최종 진단하였다. 이것은 국내에서 스테로이드 반응성 진전 증후군의 최초 보고이며, 이 질환의 임상적 그리고 신경학적 특징들을 기술하고 있다.

• 한국임상수의학회지
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• 제31권4호
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• pp.325-328
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• 2014

A 8-month-old female Maltese dog was presented with a history of heart murmur. In physical examination, grade 4/6 systolic murmur heard at the left heart base. Electrocardiography showed sinus arrhythmia, right axis deviation, deep S wave and splintered QRS complex. Thoracic radiography revealed enlarged right side heart and bulging of the main pulmonary artery. Echocardiography showed mild hypertrophy of right ventricle, a supravalvular stenosis, marked post-stenotic dilation of the main pulmonary artery and a moderately increased pulmonary arterial velocity through the stenotic area (4.4 m/s, pressure gradient of 78.7 mmHg). The dog was diagnosed with supravalvular pulmonic stenosis based on the diagnostic imaging findings. Medical management using ${\beta}1$-blocker and ACE inhibitor was started in this dog and this is first case report described diagnostic characteristic features of supravalvular pulmonic stenosis in korea.

• 한국임상수의학회지
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• 제25권2호
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• pp.106-111
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• 2008

3년령 말티즈 개(2.5Kg)가 갑작스런 심잡음, 의기소침, 식욕결핍으로 내원하였다. 혈액검사상에서 백혈구증가증과 함께 발열이 관찰되었으며 심장청진시 좌측 심첨부에서 VI/VI holosystolic murmurs가 청진되었다. 심전도에서 좌심실의 종대소견이 보였다. 진단방사선상에서 좌심방과 좌심실의 확장, 이첨판 판막의 증식이 보였으며, 이로 인해 이첨판의 역류가 관찰되었다. 이러한 임상증상과 검사 결과를 바탕으로, 본 증례는 감염성 심내막염에 의한 증식성 이첨판 역류증이라 진단하였다. 환자는 광범위 항생제, 이뇨제, 항혈전제로 치료하였다.

• Parasites, Hosts and Diseases
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• 제55권5호
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• pp.561-564
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• 2017

This report describes a dog infected with Hepatozoon canis, the first canine infection in the Republic of Korea. A 2-year-old intact male Maltese dog presented with anorexia and depression. Physical examinations revealed mild dehydration and hyperthermia ($39.8^{\circ}C$), and blood analysis showed pancytopenia. Diff-Quik staining of blood smear specimens showed the presence of ellipsoidal shaped structures (gamonts of H. canis) within a small number of neutrophils. Real-time PCR analysis using whole blood confirmed infection by H. canis. The clinical condition of the dog improved after symptomatic treatment and administration of doxycycline. Although a molecular epidemiologic survey in Korea showed H. canis infection of dogs, to our knowledge this is the first report of a dog infection in Korea molecularly shown to be H. canis.

• 한국동물위생학회지
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• 제46권3호
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• pp.249-253
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• 2023

A 12-year-old neutered male Maltese was brought to our hospital with loss of appetite, generalized alopecia, anemia, and a palpable abdominal mass. Ultrasonography revealed multiple abdominal masses in the liver and spleen. Subsequently, splenectomy and liver biopsy were performed, and the masses were histologically diagnosed as metastatic fibrosarcomas of unknown primary origin. The owner refused further investigations such as computed tomography and hepatectomy, therefore, we decided to initiate chemotherapy in the form of metronomic therapy with toceranib phosphate, which has several advantages, such as better tolerability, low cost, and convenience. The size and number of hepatic fibrosarcomas continued to increase despite continued administration of toceranib (10 mg/dog, PO, q48h). The dog died approximately 43 days after initiation of the toceranib treatment. To the best of our knowledge, this is the first report on toceranib therapy for metastatic hepatic fibrosarcoma in a dog.

• 한국임상수의학회지
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• 제21권2호
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• pp.181-183
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• 2004

Hepatic mass was aspirated under the guidance with ultrasound in 9-year old female maltese with signs of anorexia, hematochezia, vomiting, depression, and abdominal distension. Radiographic and abdominal ultrasonographic examinations were performed, which revealed enlarged tubular shaped uterine mass and solitary, small round hyperechoic hepatic mass dorsal to gall bladder as an incidental finding. Ultrasound-guided fine needle aspiration was completed, but histologic confirmation should be made for definitive diagnosis by tissue core or wedge biopsy.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2009년도 춘계학술대회
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• pp.255-255
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• 2009