• 한국임상수의학회지
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• 제29권1호
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• pp.103-106
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• 2012

A 15-year-old, spayed-female Maltese dog was presented with history of erythema and pruritus in left axillary region. In physical examination, firm elevated erythematous lesions were distributed throughout the axillary lesion. Fine needle aspiration cytology showed neoplastic epithelial cells with anisocytosis, high N:C ratio, and prominent nucleoli. Histologically, this lesion was consisted of a proliferation of undifferentiated neoplastic cells with eosinophilic cytoplasm. Mitotic figures of the neoplastic cells were observed and the neoplastic cells were intensely positive for cytokeratin. The presenting tumor was diagnosed as dermal apocrine gland adenocarcinoma.

• 한국임상수의학회지
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• 제25권6호
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• pp.533-536
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• 2008

The patient, two-year-old female Maltese dog with recurrent facial cellulitis below the left eye was referred for further investigation to the Veterinary Medical Center, Chungbuk National University. There were no visible dental problems, but extraoral radiographs showed periapical bone lyses on the left maxillary third and fourth premolars. Affected teeth were extracted by closed extraction and communication between some extraction sockets and the facial lesion was confirmed using a periodontal explorer. The facial lesion was treated as open wound. During a followup of 3 weeks, the extraction site and lesion reveal normal healing. In this case, the dog was young and had no clinically significant dental problems, like gingivitis or periodontal pocket. This case suggests that the carnassial abscess occurred secondary to cellulitis.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2009년도 춘계학술대회
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• pp.228-228
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• 2009

• 한국임상수의학회지
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• 제24권4호
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• pp.613-617
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• 2007

중성화된 1년령 말티즈 개(2.4kg)가 간헐적인 기침, 호흡곤란, 운동 불내성을 주요 증상으로 내원하였다. 신체검사 시 제 2음 모순 분열, 확장기 역류성 잡음이 관찰되었으며, 심장초음파에서 주폐동맥의 확장, 심실 중격 비대를 동반한 우심실 편심성 비대, 심각한 삼첨판 역류증과 폐동맥 역류증(5.4m/sec, 3.4m/sec)이 관찰되었다. 이러한 진단 검사 결과를 바탕으로, 본 증례를 선천성 심장 내 단락, 폐쇄성 폐질환, 그리고 우심계의 압력 과부하 또는 폐혈관계과관류와 관련된 전신질환과 감별하여 원발성 폐동맥 고혈압증으로 잠정진단 하였다. 환자는 furosemide와 aspirin을 투여하여, 산소요법을 실시하였다. 본 증례는 드물게 발생하는 개의 원발성 폐동맥 고혈압이다.

• 한국동물위생학회지
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• 제39권3호
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• pp.183-186
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• 2016

This study was performed to collect the basic data of DEA 1.1 in four small breed (Maltese, Shih-tzu, Poodle, Yorkshire terrier) and in three large breed (German shepherd, Labrador retriever and Jindo) dogs in the Daejeon area. 105 dogs from 7 breeds (Maltese=20, Shih-tzu=19, Poodle=15, Yorkshire terrier=11, German shepherd=10, Labrador retriever=10, Jindo=20) were selected and tested using the dog blood typing Kit$^{(R)}$ (Korea Animal Blood Bank Inc., South Korea). The prevalence of DEA 1.1 was 83%, that of DEA 1.2 was 17%, and there was no DEA (-) blood type identified in this study. Prevalence according to breeds was Maltese (DEA 1.1, 85%; DEA 1.2, 15%), Shih-tzu (DEA 1.1, 95%; DEA 1.2 5%), Yorkshire terrier (DEA 1.1, 91%; DEA 1.2, 9%), Labrador retriever (DEA 1.1, 90%; DEA 1.2, 10%). One hundred percent of DEA blood type 1.1 was discovered in all of the Poodles and German shepherds, and a higher prevalence of DEA 1.2 was found (DEA 1.1, 40%; DEA 1.2 60%) in Jindo dogs. The prevalence of DEA 1.2 in the Jindo dogs was significantly higher than in other breeds (P<0.01). German shepherds and Labrador retrievers may be more suitable as donor dogs than Jindo dogs in the Daejeon area. Larger scale studies are necessary from more dogs and other areas in South Korea.

• 한국임상수의학회지
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• 제31권5호
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• pp.435-438
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• 2014

11세령, 체중 2.67 kg, 암컷 Maltese의 기관 인근 경부에서 3주 전부터 종괴가 촉진되어 동물병원에 내원하였으며, 방사선 및 초음파 검사 결과 기관 및 미주신경 주위에 불투과성의 종괴가 확인되었다. 외과적으로 절제된 단일한 종괴의 크기는 $3.5{\times}2{\times}0.8cm$였다. 병리조직학적으로 큰 종양 병소가 정상 갑상선 조직과 혼재되어 있었다. 종양 병소는 형질세포와 같은 형태를 보이는 종양세포들이 모여 있는 다양한 크기의 소포로 구성되어 있고, 이 소포들은 미세한 섬유혈관중격에 의해 구획되어 있었다. 종양세포들은 인근 결합조직과 피막으로 침습하는 경향을 나타내었다. 면역조직화학염색을 실시한 결과 종양세포들은 사이토케라틴(AE1/AE3), 크로모그래닌 A, 신경원 특이 에놀라제(NSE)에 대하여 강한 양성 반응을, vimentin에는 음성 반응을 보이고 있었다. 육안병변, 병리조직학적 및 면역조직화학 염색의 특징을 토대로 본 증례는 갑상선수질암으로 진단되었다.

• 한국임상수의학회지
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• 제31권4호
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• pp.337-340
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• 2014

An 11-year-old male Maltese dog was presented with sudden onset of convulsion and right sided circling. On neurological examination, left side proprioception and menace reflexes were delayed. Blood examinations indicated severe thrombocytopenia and increased hepatic enzymes. On brain magnetic resonance imaging, lesions were founded on the left lateral subarachnoid space area. Those lesions showed hyperintense on T1-weighted images, hyperintense on T2-weighted images and hyperintense on fluid attenuated inversion recovery images. Cerebrospinal fluid analysis revealed xanthochromia and erythrophagocytosis. Coagulation test results demonstrated that fibrin degradation product and D-dimer concentrations were higher than normal range. The patient expired few hours after presentation. This case report demonstrates intracranial hemorrhage with disseminated intravascular coagulation in a dog.

• 대한수의학회지
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• 제47권1호
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• pp.85-89
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• 2007

A case of multicentric high grade T cell lymphoma is reported in a 5-year-old male Maltese dog with generalized lymphadenopathy. The dog showed depression, anorexia, blindness, jaundice, arrhythmia, and hematuria for 8 months. Complete blood count and chemistry profile revealed anemia and increased alanine transferase, alkaline phosphatase, total bilirubin, and total cholesterol. Grossly, most of lymph nodes, spleen, and liver were enlarged and neoplastic masses were occupied in these tissues. Histologically, massive accumulation of small noncleaved neoplastic lymphocytes with high mitotic figures was observed in all lymph nodes and spleen. Infiltration of neoplastic lymphocytes was also noted in the lung, liver, kidney, eye, skin, muscle, and bone marrow of femur. Immunohistochemistry revealed that tumor cells were CD3-positive and but CD79a-negative, consistent with T-cell lineage. In our best knowledge, this is the first report of multicentric lymphoma clarified the origin of tumor cells in Korea.

• 한국임상수의학회지
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• 제22권2호
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• pp.166-169
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• 2005

A 10 year-old castrated male Maltese dog with a mass on the right carpal joint was referred to the Chungnam National University Veterinary Medical Teaching Hospital. Mass size was 0.5 cm in width, 0.8 cm in length and 0.8 cm in height. Surface of the mass was hairless and ulcerated, and also the peripheral furs of mass were discolored by continuous licking. This case was diagnosed as basal cell tumor by fine needle aspiration and histopathologic examination. This dog didn't lick the carpal joint after surgery.

• 한국임상수의학회지
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• 제34권1호
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• pp.39-42
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• 2017

An 8-month-old, intact male Maltese dog was referred to us because of anorexia, diarrhea, and jaundice. Hematologic examination revealed immune-mediated hemolytic anemia, and abdominal ultrasonography revealed heterogeneous changes in mesenteric fat and coarse echotexture in the splenic parenchyma. Septic peritonitis was diagnosed on the basis of a bacterial culture test of the peritoneal fluid. Exploratory laparotomy and subsequent omental biopsy and splenectomy were performed. On histopathological examination, the omental mass and splenic lesions were diagnosed as grain foreign body granulomas. This report describes a rare case in which a grain foreign body was embedded in the spleen of a dog.