• 대한두경부종양학회지
• /
• 제33권2호
• /
• pp.43-47
• /
• 2017

Epithelial-myoepithelial carcinoma (EMC) is a rare type of low-grade malignant tumor that account for approximately 0.5% to 1% of salivary gland neoplasm and arises most commonly in the parotid gland (80%). We introduce three cases of parotid EMC arose as painless cystic mass in male patients over 70 years old. All patients were diagnosed as benign tumors (pleomorphic adenoma) by image and pathologic study (fine needle aspiration) before surgery, but the final histopathologic results were EMC. All three patients underwent parotidectomy without adjuvant radiotherapy. There were no complications such as facial paralysis. No complications or recurrences were observed during follow-up for 6 to 9 months. Since the reports of EMC are still relatively few, we report our three cases with the clinical and pathological review.

• 대한영상의학회지
• /
• 제82권1호
• /
• pp.152-161
• /
• 2021

목적 CT나 MRI에서 이하선의 양성종양, 악성종양 및 염증 질환에서 나타나는 활경근 침윤의 빈도와 어떤 상황에서 잘 일어나는지 그 조건을 알아보고자 하였다. 대상과 방법 이하선에서 발생한 양성종양 314명, 악성종양 52명 그리고 염증 22명을 대상으로 하였다. CT나 MRI에서 활경근 침윤의 빈도 및 병변의 위치, 피막침범 유무, 국소성에 따른 활경근 침윤 유무를 후향적으로 알아보았다. 결과 활경근 침윤의 빈도는 양성종양에서 0%, 악성종양에서 19.2% (10/52), 염증 환자에서 50% (11/22)였다. 피막을 침범한 염증 환자 13명 중 10명에서 활경근 침윤을 보였다. 활경근 침윤을 보인 염증 환자 11명 중 10명이 미만성을, 1명은 국소성을 보였다. 활경근 침윤을 보인 악성종양 총 10명 모두에서 피막을 침범하였으며, 그중 미만성 병변이 7명, 국소성이 3명이었다. 결론 이하선 질환에서 활경근 침윤은 악성종양보다 염증 질환에서 더 흔하게 일어났다. 염증 질환에서의 활경근 침윤은 이하선 피막을 침범하거나 미만성 병변일 경우 더 잘 나타났다.

• 대한기관식도과학회:학술대회논문집
• /
• 대한기관식도과학회 1993년도 제27차 학술대회 초록집
• /
• pp.96-96
• /
• 1993

두경부 종양의 1%를 차지하는 타액선 종양은 조직학적인 다양성 때문에 진단과 치료결정이 어렵고 자세한 병력이 중요하다. 1987년 1월부터 1992년 12월까지 본원 이비인후과에서 조직학적으로 확진된 타액선 종양 70례를 대상으로 후향적인 방법으로 성별 분포, 연령별 분포, 부위별 분포, 양성종양의 크기, 병리조직학적 분류, 중상발현 기간, 임상증상, 경부 림프절전이, 병기별 분포, 치료, 안면신경마비 및 재발 둥을 비교 분석하여 다음과 같은 결과를 얻었다. 1) 이하선에 35례(50%), 악하선에 16례(23%), 부타액선에 19례(27%) 발생했다. 2) 양성종양이 55례(79%), 악성종양이 15례(21%) 였고, 양성종양은 다형성선종이 49례(89%), 악성종양은 선낭포암이 6례(40%)로 가장 많았다. 3)증상발현 기간은 1-5년이 29례(41%)로 가장 많았다. 4) 이하선과 악하선 수술후 안면신경마비가 9례(18%)에서 있었고, 재발은 4례(6%)에서 발생하였다.

• Radiation Oncology Journal
• /
• 제16권3호
• /
• pp.251-258
• /
• 1998

목적 : 수술과 방사선치료를 받은 이하선 악성종양에서 국소 종양 제어율에 영향을 주는 요인을 알기 위하여 본 연구를 수행하였다. 대상 및 방법 : 1986년부터 1995년까지 전남대학교병원에서 이하선 악성 종양으로 수술과 방사선 치료를 함께 받은 26명을 대상으로 하였다. 대상 환자의 연령 분포는 14세부터 72세까지였고 중앙간은 55세였다. 조직학적 유형별 분포는 10명이 점액표피양암종, 7명이 편평상피세포암, 4명이 포상세포암, 4명이 선양성낭종암, 1명이 선암이었다. 수술은 15명이 이하선 전절제술, 7명이 표재성 절제술, 4명이 아전절제술을 받았다. 안면신경이 절제된 경우는 5명 있었다. 수술 후 병리학적으로 잔존 병변이 있었던 경우가 4명, 절제연 양성이 4명이었다. 방사선치료는 선형가속기의 광자선과 전자선속을 사용하였다. 26명 중 11명은 광자선만으로 치료하였고 전자선이 병용된 경우는 15명이었으며 전자선량은 900 cGy부터 3800 cGy (중앙값: 1760 cGy)까지였다. 이하선종양 부위에 조사된 총방사선량은 5000 cGy부터 7560 cGy (중앙값 : 6020 cGy)까지였다. 대상 환자들의 최소추적기간은 2년이었다. 국소종양제어율의 산출은 Kaplan-Meier법을 이용하였고 단변량분석에는 generalized Wilcoxon test, 다변량분석에는 Cox 모델을 이용하였다. 결과 : 방사선 치료 후 국소종양의 재발은 25명 중 5명 (19$\%$)에서 관찰되었으며 국소종양제어율은 5년에 77$\%$였다. 환자의 5년 생존율은 70$\%$였다. 성별, 연령 (>60세), 종양크기 (>4 cm), 수술소견상 경부림프절 침범과 신경 침범, 절제연 침범 여부 및 총방사선량 (>60 Gy)의 요인이 국소 종양 제어율에 미치는 영향을 단변량 분석한 결과 종양 크기 (p=0.002), 절제연 침범 여부(p=0.011)에 따라 국소종양제어율에 있어서 통계학적으로 의의가 있는 차이를 보였다. 같은 요인들에 대한 다변량 분석에서는 종양 크기 (p=0.022)만이 국소 종양 제어율에 관련이 있는 것으로 나타났다. 결론 : 국소종양 제어율에 영향을 주는 여러가지 예후 인자들의 다변량 분석에서 종양 크기만이 의의가 있었으나 앞으로 더욱 많은 환자를 대상으로 연구가 요구된다.

• 대한두경부종양학회지
• /
• 제16권1호
• /
• pp.37-41
• /
• 2000

Background and Objectives: The most commonly used incision for parotidectomy is modified Blair incision, but it has unsatisfactory cosmetic result due to long exposed scar in the neck. Therefore, we introduce an alternative approach with more acceptable scar named modified facelift incision. We report it's techniques, indications and disadvantages with our experiences. Materials and Methods: During the 1999, 15 patients were underwent parotidectomies using modified facelift incision. We studied the postoperative complications and the cosmetic results respectively. Results: There were 11 benign tumors, 3 malignant tumors, and 1 chronic inflammation. Total parotidectomy was performed in 2 malignant tumors and chronic parotitis patients. The others has superficial parotidectomy. In terms of operation field, there was no difference between classical incision and facelift incision. Partial facial nerve palsy was noted in 2 cases, who required sacrifice of branches of facial nerve because of malignant tumor invasion. There were no specific complications associated with this type of approach. Postoperative cosmetic results were satisfactory in all cases. Conclusion: Modified facelift incision provides better cosmetic result than conventional incision without narrowing of operation field. We believe that it is a safe alternative approach to all parotidectomy cases especially to women and patient with keloid skin. The only limitation of this incision is poor adaptability for combining neck dissection.

• 대한세포병리학회지
• /
• 제13권1호
• /
• pp.42-46
• /
• 2002

Epithelial-myoepithelial carcinoma(EMC) is a rare, low grade malignant tumor of the salivary glands. The EMC has a distinctive histological appearance comprising ductal structures with an inner epithelial cell component and an outer layer of myoepithelial cells which show plump clear cytoplasm. The cytologic features of the EMC have been rarely described. A correct cytological diagnosis to this rare tumor is difficult with high false negative rate. We report a case of EMC in which fine needle aspiration cytologic findings were misinterpreted as a pleomorphic adenoma.

• 대한두경부종양학회지
• /
• 제40권1호
• /
• pp.27-31
• /
• 2024

Mucoepidermoid carcinoma is one of the most common malignant tumors that occur in the salivary glands. While several cases of distant metastasis have been reported, instances of metastasis to the skin are rare. We present the case of a 72-year-old man diagnosed with parotid mucoepidermoid carcinoma who experienced temporary remission following surgical resection and adjuvant chemoradiotherapy. However, the carcinoma recurred along the skin at the periauricular area along the mask line. Given the current prevalence of COVID-19, the practice of wearing masks has become more widespread. This case report highlights the recurrence of mucoepidermoid carcinoma along the mask strap line, emphasizing the importance of distinguishing it from benign dermatological conditions.

• 대한두경부종양학회지
• /
• 제40권1호
• /
• pp.37-41
• /
• 2024

Carcinoma ex pleomorphic adenoma is an uncommon malignant salivary gland tumor that arises from a long-standing pleomorphic adenoma. The carcinomatous component of carcinoma ex pleomorphic adenoma can possess virtually any histologic subtype of salivary gland cancer. We experienced a case of a 61-year-old patient who presented with a right parotid mass that was initially palpated 20 years ago, with a sudden increase in size in the last few months. Radiological and cytological findings from fine needle aspiration biopsy could not exclude malignancy. Total parotidectomy and selective neck dissection were performed for treatment, and carcinoma ex pleomorphic adenoma with mixed carcinoma components of salivary duct carcinoma and myoepithelial carcinoma was diagnosed. After receiving postoperative radiation of 6000 cGy over 6 weeks, there has been no recurrence up to the 18-month follow-up. We report this rare case of carcinoma ex pleomorphic adenoma with mixed malignancy subtypes, accompanied by a review of literature.

• 대한기관식도과학회지
• /
• 제4권2호
• /
• pp.211-218
• /
• 1998

There have been few large scale surveys of salivary gland tumors, because the salivary gland tumors comprised less than 3 percent of all neoplasms of the head and neck. Also there is a problem that the incidences of specific types of tumors have the variation according to the geographic regions. ]'nother Korean reports about salivary gland tumor, they only treated about 100 cases only. Objectives : The purpose of this study is to identify the frequency and clinical characteristics of salivary gland tumors and to compare with other Korean reports. Materials and Methods : We had performed to analyze 387 cases of salivary gland tumors from 1983 to June 1997, were reviewed in histopathological and clinical aspects. The diagnoses of individual tumors were based on the World Health Organization classification. Tumors were analyzed according to the histologic type site, age and sex. Results : The majority (79.1%) of cases occurred in the major salivary glands and 20.9% in the minor. The parotid gland was the most frequent site with 52.4％ and submandibular glands with 26.3%. Benign tumors were 79.3% of the tumors and malignant tmon were 20.7%. The most frequent tumor was pleomorphic adenoma occupied 63.8% of the total and frequency percent of histologic type of 98 malignant tumors showed 35.7% of mucoepidermoid carcinomas, 24.5% of adenoid cystic carcinomas. Overall gender with female predominance with 1 : 1.4 of male to female ratio. The average age of patients was 42.8 years. The most frequent chief complaint was a palpable mass. The duration of the symptom was shorter in the malignant salivary gland tumors (26.7 months) than in the benign salivary gland tumors (38.2 months). Conclusion : Comparing to the previous Korean reports, the present study confirms that the incidence of salivary gland tumor was lower in the parotid gland, and was higher in the submandibular and minor salivary glands.

• 대한두개안면성형외과학회지
• /
• 제20권6호
• /
• pp.412-415
• /
• 2019

Salivary gland tumors usually appear in solitary mass in single salivary gland. The coexistence of tumors with different histological types occurring within a unilateral parotid gland is an extremely rare event. We experienced a case which two different types of malignant tumors developed at different time points in same gland; metachronous tumors. The second tumor was excised widely and reconstruction was performed by free tissue transfer. Sensory and motor nerve to the left cheek appeared to be intact, and circulation was adequate. This rare case was presented in this article.