• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.18 no.10
• /
• pp.2503-2508
• /
• 2014

This study is about the selection and noise test of electronic sensor which is preceded by electric Operating Cell(EOC) development using electronic sensor technology to solve the structural weakness of Mechanism Operated Cell(MOC) in VCB, and has a final target in product development minimizing contact malfunction of the chattering or rebounce states caused by existing MOC. In this test results, when opening and closing VCB, rising velocity of surge voltage in opening time was measured 4.2 times faster than closing time and noise decibel value was measured respectively 120dB and 110dB. When supplying 60kV power frequency overvoltage, we found that sensor output graph in VCB opening and closing times operated stably without distortion. When supplying 150kV $1.2{\times}50{\mu}s$ impulse frequency voltage, we found that voltage graph of output contact in sensor opening and closing sides maintained a normal condition without distortion, and when supplying 2500A current, we found that tested result of electric field noise operated stably without distortion.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.29 no.1
• /
• pp.18-26
• /
• 2015

Akebiae Caulis is a galenical originated from Akebia quinata Decaisne species. It is commonly used in the treatment of oposiuria, inflammation, nociceptive and fever. Here, we investigated the effect of Akebiae Caulis extract (ACE) to protect hepatocyte against the malfunction of mitochondria and apoptosis. Arachidonic acid (AA)+iron promoted excessive reactive oxygen species (ROS) production and exerted a deleterious effect on mitochondria. Treatment with ACE protected hepatocytes from AA+iron-induced cytotoxicity, as shown by alterations in the protein levels related with apoptosis such as poly(ADP-ribose) polymerase, pro-caspase 3, Bcl-XL and Bcl-2. Moreover, AA+iron-induced $H_2O_2$ production, GSH depletion and mitochondrial dysfunction were alleviated by ACE pretreatment. As a potential molecular mechanism for the ACE-mediated cytoprotection, phosphorylation of AMP-activated protein kinase (AMPK), a key regulator in determining cell survival or death, was increased by ACE. Moreover, ACE treatment enhanced inactive phosphorylation of glycogen synthase kinase-$3{\beta}$ ($GSK3{\beta}$), downstream substrate kinase of AMPK. More importantly, ACE prevented a decrease in the $GSK3{\beta}$ phosphorylation derived by AA+iron, which might contribute to mitohondiral protection and cell survival. To further identify essential compounds in Akebiae Caulis for the protection of AA+iron-mediated cytotoxicity, we found that betulin in combination with hederagenin protected from AA+iron-induced mitochondrial dysfunction. Betulin+hederagenin treatment also increased inactive phosphorylation of $GSK3{\beta}$ in common with ACE. These results suggest that ACE protected hepatocytes against oxidative stress and mitochondrial dysfunction, which is mediated with inactive $GSK3{\beta}$ phosphorylation downstream of AMPK.

• The Journal of the Korea Contents Association
• /
• v.21 no.1
• /
• pp.426-433
• /
• 2021

Investment in public sector information services has been on the rise in recent years. The supply of high-speed Internet and smartphones has become more common, and the stability of the information system provided to the public in the public sector has become an important management factor. In other words, tasks such as handling civil complaints and issuing certificates by public institutions, financial transactions by banks, customs clearance work, and e-commerce by individuals or institutions are mostly done online. Therefore, how to deal with obstacles arising from the information system, which is in charge of important civil service affairs, is becoming a very important issue. In other words, in the case of a disability that does not function normally even for a short period of time, various problems can occur when the work is delayed, as well as causing serious financial damage to the civil petitioner. This could be accompanied by a decline in public confidence and various other damages such as filing civil complaints. The reasons for the occurrence of information system failures are very diverse and realistically difficult to predict when. Among the various measures to cope with disability, this paper proposed a plan to establish a disability situation notification system that can minimize confusion caused by disability in the event of a homepage malfunction. The proposed disability situation notification system was established in the public IDC environment to show the possibility of utilization.