• Health Policy and Management
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• v.33 no.1
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• pp.75-84
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• 2023

Background: The purpose of this study was to identify the factors affecting social discrimination experience on depression in the early and late elderly by region. Methods: This study used data from the National Survey of Older Koreans 2020. The subject of the study was the elderly aged 65 or older, and it was analyzed as those who responded. In order to analyze the effect of social discrimination experiences on depression, it was analyzed through binary logistic regression analysis. Results: The results of this study showed that the elderly who experienced social discrimination had a significant effect on depression. In addition, when four groups experienced social discrimination when using restaurants or coffee shops, depression was commonly affected. In addition, when both city and rural areas experience social discrimination when using sales facilities in social discrimination in the elderly, city areas are 2.21 times more likely to experience depression and 3.52 times more likely to experience depression in rural areas. The late elderly are more likely to experience 3.04 times more likely to experience social discrimination when using restaurants or coffee shops in city areas, and 3.03 times more likely to experience depression when experiencing social discrimination to make major decisions in the family in rural areas. Conclusion: In conclusion, it is necessary to prepare alternatives to prevent depression and improve mental health suitable for the characteristics of age and residential area. In addition, it suggests that personal and social efforts are needed to solve the problem of social discrimination in order to reduce depression in the elderly.

• Nuclear Medicine and Molecular Imaging
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• v.43 no.2
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• pp.107-111
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• 2009

Purpose: The authors analyzed how the regional cerebral blood flow(rCBF) findings of patients with major depression differ from the normal control, and our results were compared to previous reports. Materials and Methods: Twelve patients fulfilling DSM-IV criteria for major depression who were off all psychotropic medications for > 4weeks(male: 7, female: 5, age range: $19{\sim}52$ years, average age: $29.3{\pm}9.9$ years) and 14 normal volunteers(male: 8, female: 6, age range: $19{\sim}53$ years, average age: $31.4{\pm}9.2$ years) were recruited. Images of brain perfusion SPECT were obtained using Tc-99m ECD and patterns of the rCBF were compared between patients with major depression and the healthy control subjects. Results: The patients with major depression showed increase of the r-CBF in right lingual gyrus, right fusiform gyrus, left lingual gyrus, left precuneus, and left superior temporal gyrus, and showed decrease of r-CBF in right pons, left medial frontal gyrus, cingulate gyrus of left limbic lobe, cingulate gyrus of right frontal lobe, and cingulate gyrus of right limbic lobe compared to the normal control. Conclusion: The Tc-99m ECD brain perfusion SPECT findings in our study did not differ from the previously reported regional cerebral blood flow pattern of patients with major depression. Especially, decreased rCBF pattern typical to major depression patients in the right pons, left medial frontal gyrus, and cingulate regions was clearly demonstrated.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.3-11
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• 1999

At the beginning, researches on the biology of depression or affective illness have focused mainly on the receptor functions and neuroendocrine activities. And the studies of the past years did not break new theoretical background, but the recent advances in the research on the molecular mechanisms underlying neural communication and signal transduction do add some insights to many established ideas. This article will overview some of the more recent advances in the clinical researches of depression. Our major concerns to be presented here include the followings : (1) alterations in the post-synaptic neural transduction ; (2) changes in the neurons of hypothalamic neuropeptides ; (3) decreased peptidase enzyme activities ; (4) associations of hypothalamic-pituitary-adrenal axis abnormalities with serotonin neurotransmission ; (5) role of serotonin transporter ; (6) changes in the responsiveness of intracellular calcium ion levels ; (7) the inositol deficiency theory of lithium and depression ; (8) the transcription factors including immediate early genes ; (9) recent genetic studies in some families. This brief overview will suggest that changes in DNA occur during antidepressant therapy. These changes at the DNA level initiating a cascade of events underlying antidepressant modality will give us the insights on the molecular biological basis of the pathogenesis of depression and cues for a new class of antidepressants.

• Journal of Preventive Medicine and Public Health
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• v.51 no.2
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• pp.100-108
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• 2018

Objectives: Family members are often cancer patients' primary source of social and emotional support and make a major contribution to how well patients manage their illness. We compared the prevalence of depression in the family members of cancer patients and the general population. Methods: This study used the data from the fourth, fifth, and sixth rounds of the Korea National Health and Nutrition Examination Survey. The variable of interest was the presence of a cohabitating cancer patient in the family and the dependent variable was the presence of diagnosed depression. Results: The odds of having medically diagnosed depression in those with a cohabitating cancer patient in the family were significantly higher than among those who did not have cancer patients in their families (odds ratio [OR], 1.56; 95% confidence interval [CI], 1.12 to 2.17; p=0.009). The OR for females was 1.59, and this increase was statistically significant (95% CI, 1.09 to 2.31; p=0.02). Conclusions: We need to invest more effort into diagnosing and managing depression in the family members of cancer patients. This will have an impact both on their quality of life and on the well-being of patients, as supporters and caregivers play an instrumental role in helping patients manage their illness.

• Korean Journal of Health Education and Promotion
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• v.32 no.3
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• pp.57-71
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• 2015

Objectives: The purpose of this study was to investigate the effect of problem drinking on life satisfaction and to analyze the mediating effect of family conflict and depression between two variables. Methods: The data of this study were selected in the 9th Korea Welfare Panel Survey(KYPS, 2014). The SPSS Ver. 18.0 statistical package was used for descriptive statistics analysis, correlation analysis, and hierarchical regression analysis. Results: The major findings were as follows; First, problem drinking was found to have a negative impact on family conflict, depression, and life satisfaction. Second, family conflict and depression were identified to cause decreasing life satisfaction. Third, family conflict and depression was found to have a mediating effect between problem drinking and life satisfaction. Conclusions: In order to enhance life satisfaction through overcoming problem drinking, drinking prevention programs and recreational programs based on economic and social context are required.

• Journal of Families and Better Life
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• v.30 no.3
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• pp.165-177
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• 2012

This study examined the effect of social support on infant mother's parenting behavior and mediating effects of parenting stress and depression between social support and maternal parenting behavior. Participants were 2078 mothers of infant (4-10 month) in Korea. Data were analyzed by Structural Equation Model. Major findings were as follows: First, social support showed direct effect on maternal parenting behavior. That was the more mother receive social support, mother show responsive and warmer parenting behavior on infant. Second, maternal parenting stress mediated the effect of social support on maternal parenting behavior. That was the more mother receive social support, the less mother experience parenting stress, which in turn contribute to responsive and warm parenting behavior. Third, Maternal depression didn't mediate the effect of social support on maternal parenting behavior. However, social support and maternal parenting stress showed direct effects on maternal depression. This research suggest the needs for development of diverse social support policies and program to help mothers reduce maternal parenting stress and depression.

• Journal of the Korean Society of School Health
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• v.30 no.3
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• pp.274-283
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• 2017

Purpose: The purpose of this study was to investigate the mediating effects of self-esteem and self-resilience while identifying the relationship between bullying victimization (being bullied) and depression based on a longitudinal study design. Methods: Participants were adolescent cohort of 1,971 middle school students participating in 2013 and 2014 Korean Children and Youth Panel Survey conducted by National Youth Policy Institute. Data were analyzed by Pearson's Correlation and regression. Results: The major findings are as follows. First, self-esteem and self-resilience were positively related to each other and negatively related to depression and bullying victimization. Second, bullying victimization effected the level of depression of adolescents and self-esteem played a mediating role between bullying victimization and depression while self-resilience did not. Conclusion: The results suggest that emotional factors continue to play an important role in promoting psychological adjustment of victims of bullying. Therefore, interventions are more likely to be successful if they focus on emotional skills development of adolescents.

• Korean Journal of Child Studies
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• v.27 no.5
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• pp.67-78
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• 2006

This study investigated interaction effects of stress and coping strategies on depression among middle school students. The scale created to measure coping strategies included three types of coping strategies : problem-focused, emotion-discharge, and affective-regulation. Two hundred forty-four students were selected from juniors of two middle schools in Seoul. Boys used problem-focused and affective-regulation coping strategies more than emotion-discharge coping strategies. Girls used affective-regulation coping strategies most frequently. The interaction effects of emotion-discharge coping strategies for boys and problem-focused coping strategies for girls were significant. Findings were discussed in developing coping education programs for intervention of adolescent depression.

• Journal of Family Resource Management and Policy Review
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• v.20 no.1
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• pp.141-158
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• 2016

The purpose of this study was to analyze the effects of family stress on instances of depression in married, middle-aged women; more specifically, this study examined the moderating effects family strength and support have on depression in middle-aged women. Three hundred women from 40 to 60 years of aged, all of whom resided in Gyeonggi-do, participated in this study. For the final analysis, 249 self-reported questionnaires were used. Descriptive statistics, correlative analysis, and multiple regression analysis were conducted using SPSS ver. 21.0. The major results of this study were as follows. First, the mean scores of family strengths and family support were higher than the median scores. The mean level of depression was lower than the median of depression frequency, while the mean for the family stress scores was the same as the median. Second, depressions frequency was influenced by family type, health status, and average income. There was a positive correlation between depression and family stress. Third, family support had a moderating effect on depression. Family strength did not seem to have the same moderating effect, while there did seem to be a moderating effect of instrumental support from families on the relationship between family stress and depression. In conclusion, to decrease the frequency of depression in married, middle-aged women', it may be necessary to increase family support, and it seems to be especially necessary to increase the amount of instrumental support from families.

• The Journal of the Korea Contents Association
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• v.14 no.11
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• pp.810-819
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• 2014

Objectives: The aim of this study was to investigate the sleep quality and depression, and relationship between sleep quality and depression of nursing students. Methods: A cross-sectional, descriptive study was conducted. The subjects were 268 nursing students from a University. Data were collected on September, 2012 by using a structured questionnaire. The data were analyzed using SPSS/WIN 19.0 program. Results: The mean score of sleep quality was 6.65, among the students, 86.6% had sleep problem. The mean score of depression was 16.89, 25.4% of the students had mild depression, and 20.5% had severe depression. Sleep quality showed no significant differences, meanwhile depression showed significant differences according to the school year, satisfaction level with nursing major and university. There was a significant relationship between sleep quality and depression. Conclusions: These results suggest that some of the nursing students have sleep problem and depression. Therefore, it is needed to develop various nursing intervention strategies to improve physical, psychological health of the nursing students.