• Proceedings of the IEEK Conference
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• 2006.06a
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• pp.871-872
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• 2006

In this paper, we designed bio-signal acquisition system in Magnetic Resonance Imager(MRI) Environment. In MRI Environment, Strong RF Pulse and Gradient Field Switching Noise exist and can cause distortion of ECG. By this, ECG can lose their important information. So we proposed a bio-signal acquisition system with robust immunity to RF pulse and gradient switching noise. In conclusions, the proposed system showed the prevent saturation of measured biosignal and possibility of using cardiac gating and respiration gating method.

• Journal of the Korean Chemical Society
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• v.62 no.3
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• pp.187-190
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• 2018

A three-component coupling reaction of phenylacetylene, p-toluenesulfonyl azide, and water through copper catalysis is described to provide knowledge of spectroscopy and catalytic reactions and to introduce current research topics in organic chemistry for second-year undergraduate students. In the presence of stoichiometric amounts of phenylacetylene, p-toluenesulfonyl azide, and triethylamine, the reaction was performed with 4 mol% CuCl in water as the sole solvent and was completed in 1.5 h. A practical purification method and recrystallization of the crude reaction mixture resulted in the rapid isolation of the desired product with yields of 42~65%. Students characterized 4-methyl-N-(phenylacetyl)benzenesulfonamide by using melting-point determination, infrared spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy. This experimental procedure and spectroscopic data analysis will serve as a platform for students to apply classroom knowledge in practical state-of-the-art research.

• Korean Journal of Biological Psychiatry
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• v.21 no.4
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• pp.128-140
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• 2014

Anxiety disorders are characterized by dysregulation of neuroendocrine, neurotransmitter and neuroanatomical functions. Substantial advances in research method offered new insights into the neurobiologic mechanisms in anxiety disorders. Advances in molecular biology have enabled illumination of hormone and neurotransmitters that have important roles in anxiety. The neuroanatomic circuits related to anxiety are also being elucidated by improvements in neuroimaging technology such as structural and functional magnetic resonance imaging. This article reviews the research data in relation to the neurobiology underlying fear and pathologic anxiety and discusses their implications for development of biological treatments for anxiety disorders.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.126-126
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• 2002

Purpose： For quantitative analysis of the cardiac diseases, it is necessary to segment the left-ventricle(LV) in MR cardiac images. Snake or active contour model has been used to segment LV boundary. In using these models, however, the contour of the LV may not converge to the desirable one because the contour may fall into local minimum value due to image artifact in inner region of the LV Therefore, in this paper, we propose the new preprocessing method using K-means clustering and merging algorithms that can improve the performance of the active contour model.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.104-104
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• 2002

목적： SAAV sequence를 이용하여 동시에 획득한 동맥과 정맥의 두 MRA 영상을 Color Mapping으로 동맥과 정맥을 구분하여 한 영상에 나타냄으로써 AVM 이나 DAVF 등과 같은 혈관질환의 임상적 진단 및 치료에 도움을 주고자 하였다. 대상 및 방법： 일반적으로 MRA 영상은 사전 포화방법(presaturation)을 이용한 2D TOF 기법을 통하여 동맥과 정맥을 구분하여 영상을 획득한다. 이러한 일반적인 사전포화방법을 응용한 SAAV 기법은 일정영역을 미리 포화(saturation)시킨 후 포화영역의 위, 아래의 영역을 한번에 영상화하여 동맥과 정맥의 구분된 영상을 한번에 획득할 수 있다. 마산 삼성병원의 0.3T MRI system(Megfinder, AILab. Korea)에서 SAAV sequence를 이용하여 정상적인 피험자로부터 목 부위의 동맥과 정맥 혈관영상을 동시에 얻었다. 이들의 각 2D 영상을 Color Mapping으로 조합한 후 Maximum Intensity Projection(MIP) 기법을 통해 3D Artery-Vein Color Mapping(AVCM) MRA 영상으로 재구성하였다. 3명의 피험자에 대한 SAAV MRA data를 256$\times$256$\times$64(resolution： 0.89$\times$0.89$\times$2㎣)로 획득하였다.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.79-79
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• 2002

Purpose： The reliability of absolute quantification of average metabolite concentrations in the human brain in vivo by H-MRS using the fully relaxed water signal as an internal standard was evaluated in a number of in vitro as well as in vivo measurements. Method： The experiments were performed on 3T MEDINUS MAGNUM MR-scanner using a STEAM sequence.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.85-85
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• 2002

Purpose： To evaluate the white matter fiber connectivity of normal human using diffusion tensor MRI. Method： Normal young healthy volunteers (2 women and 1 man) and 3 brain tumor patients participated in this study. All studies were performed using a 1.5T Philips Gyroscan Intern system. Diffusion weighted imaging was performed using single-shot echo planar imaging, with navigator echo phase correction and SENSE. Diffusion weighting was performed along six independent axes, using diffusion weighting of b=800s/$\textrm{mm}^2$. 128matrix, 23cm FOV, 2.5mm slice thickness were used for Imaging parameters. Data were processed on a Window-2000 PC equipped with IDL and PRIDE (Philips Medical System). Corticospinal tract was traced from mid-pons level via posterior limb of internal capsule. Corpus callosum, cerebellar peduncles and frontal fibers were traced by fiber tractography.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.114-114
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• 2002

Purpose： To know the fate of Gadophrin-2-enhanced areas in hearts with acute reperfused myocardial infarction. Method： The left anterior descending branches of coronary arteries were occluded for 90 min and reperfused for 60 min in 15 rabbits. Then, Gadophrin-2 (0.05 mmol/kg) was injected via ear veins. Short-axial T1-weighted spin echo images and fast cine images were obtained 24 hours after injection of Gadophrin-2. After four weeks, short-axial cine MRI was performed and T1-weighted spin echo Images were obtained 5 min and 15 min after injection of Gd-DTPA (0.2 mmol/kg). The animals were sacrificed and short-axial slices of the specimen were stained with 1.5% triphenyltetrazolium chloride (TTC) solution.

• The Journal of the Acoustical Society of Korea
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• v.26 no.1E
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• pp.27-32
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• 2007

Hydraulic actuator and electro-magnetic liner actuator have been used as typical active vibration control methods. However these methods have many kinds of disadvantages such as causing space limit, difficult maintenance, complicate structures, etc. The purpose of this paper was to study on the possibility of active vibration control using piezoelectric transducer. Piezoelectric transducer generated a vibration and GIC (General Impedance Converter) amplifier was adopted to give adjustable vibration signal to transducer and high amplitude of vibration. Resonance frequency of piezoelectric transducer was controlled by GIC amplifier and higher amplitude of vibration was achieved. Finally active vibration control using piezoelectric transducer was performed.

• Proceedings of the KIEE Conference
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• 1999.07g
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• pp.3153-3155
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• 1999

최근 수년간 의료영상분야는 국내외적으로 급격한 발전을 거듭하고 있다. 특히 자기공명영상장치 (Magnetic Resonance Imaging), X-ray CT(Computed Tomography)와 단층촬영장치는 인체내부를 비침습적(non-invasive)으로 영상화함으로써 해부학적인 질병진단에 많은 장점을 가지고 있다. 이와같은 단층영상 재구성에는 역매트릭스법(matrix inversion). 반복재구성법(interative method), 역투영 법(back-projection), 2차원 Fourier 변환법(2D FFT), 중첩재구성법(Filtered back-projection) 등의 다양한 알고리즘을 사용하고 있다. 본 연구에서는 X-ray CT에서의 단층영상재구성 기법 중 널리 사용되고 있는 Filtered Back Projection 기법의 연산순서도와 연산량을 분석하고 이를 시뮬레이션을 통하여 확인하고 실시간 영상재구성을 위하여 범용 Digital Signal Processor의 병렬처리시스템 구성에 기반된 최적 Architecture를 선정하고자 한다.