IN VIVO H-MRS QUANTIFICATION OF BRAIN METABOLITES USING WATER AS AN INTERNAL STANDARD

  • Lee, Jung-Woo (Department of Biomedical Engineering, College of Medicine, Kangnam St. Mary′s Hospital, The Catholic University of Korea) ;
  • Choe, Bo-Young (Department of Biomedical Engineering, College of Medicine, Kangnam St. Mary′s Hospital, The Catholic University of Korea) ;
  • Baik, Hyun-Man (Department of Biomedical Engineering, College of Medicine, Kangnam St. Mary′s Hospital, The Catholic University of Korea, Medinus Co. LTD. Korea) ;
  • Chung, Sung-Taek (Medinus Co. LTD. Korea) ;
  • Lee, Hyoung-Koo (Department of Biomedical Engineering, College of Medicine, Kangnam St. Mary′s Hospital, The Catholic University of Korea) ;
  • Suh, Tae-Suk (Department of Biomedical Engineering, College of Medicine, Kangnam St. Mary′s Hospital, The Catholic University of Korea)
  • Published : 2002.11.01

Abstract

Purpose: The reliability of absolute quantification of average metabolite concentrations in the human brain in vivo by H-MRS using the fully relaxed water signal as an internal standard was evaluated in a number of in vitro as well as in vivo measurements. Method: The experiments were performed on 3T MEDINUS MAGNUM MR-scanner using a STEAM sequence.

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