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No Association of Cytochrome P450-1B1 Gene Polymorphisms with Risk of Breast Cancer: an Egyptian Study

  • Ibrahim, Mona H;Rashed, Reham A;Hassan, Naglaa M;Al-azhary, Nevin M;Salama, Asmaa I;Mostafa, Marwa N
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2861-2866
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    • 2016
  • It is thought that population characteristics of breast cancer may be due to a variation in the frequency of different alleles of genes such as CYP1B1. We aimed to determine the association of CYP1B1 polymorphisms in 200 breast cancer cases and 40 controls by PCR-RFLP. Frequencies were assessed with clinical and risk factors in Egyptian patients. The genotype LV and the Leu allele frequencies for patients and controls were 42.9% and 50%, and 52.9% and 53.3%, respectively), with no significant differences observed (P values = 0.8 and 0.6, respectively). There was also no significant association between genotypes and any risk factors for cases (P>0.05) except laterality and metastasis of the tumor (P values=0.006 and 0.06, respectively). The CYP1B1 polymorphism Val432Leu was not associated with breast cancer in Egypt, but may provide clues for future studies into early detection of the disease.

The Role of Training and Absorptive Capacity in Mediating Human Capital Dimensions and Organizational Performance: Evidence from Pakistan

  • BHUTTO, Sana Arz;JAMAL, Yasir;RAFIQ, Asim;MEHMOOD, Kashif;HUSSAIN, Munir;ALI, Amjad
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.12
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    • pp.473-484
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    • 2021
  • This study aims to examine the role of training and absorptive capacity as a mediator to examine the impact of human capital dimensions on the performance of an organization. This study employs the quantitative approach for analysis. A sample of 208 respondents was collected from the textile factories based in Karachi and Faisalabad. Data was analyzed using the PLS-SEM technique. PLS-SEM algorithm was used to check the validity and reliability of the data. PLS-SEM bootstrapping was used for studying the impact. The results show that the skills have an insignificant impact on organizational performance. Education and skills have an insignificant indirect impact on the performance of an organization. The research findings show that the human capital dimensions are full and partially mediated via absorptive capacity and training. The findings revealed that if we implement one by one dimension of human capital then it will not cause any increase in the organization's performance but if we implement all dimensions then it results in optimal performance. Thus, this study suggests adopting effective training techniques and creating absorptive capacity in an organization to increase the performance of an organization. The findings of this study significantly contribute to the existing body of knowledge.

Digital Divide in Riyadh Neighborhoods: A Spatial Analysis

  • Rawan, Almutlaq;Shuruq, Alshamrani;Ohoud, Alhaqbani;Fatimah, Altamimi;Ghadah, Alammaj;Omer, Alrwais
    • International Journal of Computer Science & Network Security
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    • v.23 no.1
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    • pp.17-24
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    • 2023
  • The objective of this paper is to use Geographical Information Systems for identifying Digital Divide in Riyadh Neighborhoods, Saudi Arabia. Geo-database was created that includes Streets, Neighborhoods, ICT Access Data and Coverage Map for Riyadh. We used QGIS and overlay for analysis, intersection selected as tool for this paper. The results indicate that after analyzing the use of information communication technology in all regions of the Kingdom it turns that Riyadh, Ash Sharqiyyah and Makkah in average with percentage 50%, While Al Jawf, Al Madinah, and Najran are the least with percentage 42%. Then we focused on Riyadh to analyze the digital divide because it is the capital of Saudi Arabia and occupations the highest percent of communications towers in the KSA due to population density. Regarding coverage of the 4G, the neighborhoods at the center have recorded very high coverage score. While neighborhoods at the edges of the city have low values of coverage score. Same for 3G, it is more intense in the center and the coverage percentage is higher than 4G. For 2G we found it had the highest coverage compared to 3G or 4G

Certificate Revocation in Connected Vehicles

  • Sami S. Albouq
    • International Journal of Computer Science & Network Security
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    • v.23 no.5
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    • pp.13-20
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    • 2023
  • In connected vehicles, drivers are exposed to attacks when they communicate with unauthenticated peers. This occurs when a vehicle relies on outdated information resulting in interactions with vehicles that have expired or revoked certificates claiming to be legitimate nodes. Vehicles must frequently receive or query an updated revoked certificate list to avoid communicating with suspicious vehicles to protect themselves. In this paper, we propose a scheme that works on a highway divided into clusters and managed by roadside units (RSUs) to ensure authenticity and preserve hidden identities of vehicles. The proposed scheme includes four main components each of which plays a major role. In the top hierarchy, we have the authority that is responsible for issuing long-term certificates and managing and controlling all descending intermediate authorities, which cover specific regions (e.g., RSUs) and provide vehicles with short-term pseudonyms certificates to hide their identity and avoid traceability. Every certificate-related operation is recorded in a blockchain storage to ensure integrity and transparency. To regulate communication among nodes, security managers were introduced to enable authorization and access right during communications. Together, these components provide vehicles with an immediately revoked certificate list through RSUs, which are provided with publish/subscribe brokers that enable a controlled messaging infrastructure. We validate our work in a simulated smart highway environment comprising interconnected RSUs to demonstrate our technique's effectiveness.

INTRINSIC THEORY OF Cv-REDUCIBILITY IN FINSLER GEOMETRY

  • Salah Gomaa Elgendi;Amr Soleiman
    • Communications of the Korean Mathematical Society
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    • v.39 no.1
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    • pp.187-199
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    • 2024
  • In the present paper, following the pullback approach to Finsler geometry, we study intrinsically the Cv-reducible and generalized Cv-reducible Finsler spaces. Precisely, we introduce a coordinate-free formulation of these manifolds. Then, we prove that a Finsler manifold is Cv-reducible if and only if it is C-reducible and satisfies the 𝕋-condition. We study the generalized Cv-reducible Finsler manifold with a scalar π-form 𝔸. We show that a Finsler manifold (M, L) is generalized Cv-reducible with 𝔸 if and only if it is C-reducible and 𝕋 = 𝔸. Moreover, we prove that a Landsberg generalized Cv-reducible Finsler manifold with a scalar π-form 𝔸 is Berwaldian. Finally, we consider a special Cv-reducible Finsler manifold and conclude that a Finsler manifold is a special Cv-reducible if and only if it is special semi-C-reducible with vanishing 𝕋-tensor.

Design and SAR Analysis of Wearable Antenna on Various Parts of Human Body, Using Conventional and Artificial Ground Planes

  • Ali, Usman;Ullah, Sadiq;Khan, Jalal;Shafi, Muhammad;Kamal, Babar;Basir, Abdul;Flint, James A;Seager, Rob D.
    • Journal of Electrical Engineering and Technology
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    • v.12 no.1
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    • pp.317-328
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    • 2017
  • This paper presents design and specific absorption rate analysis of a 2.4 GHz wearable patch antenna on a conventional and electromagnetic bandgap (EBG) ground planes, under normal and bent conditions. Wearable materials are used in the design of the antenna and EBG surfaces. A woven fabric (Zelt) is used as a conductive material and a 3 mm thicker Wash Cotton is used as a substrate. The dielectric constant and tangent loss of the substrate are 1.51 and 0.02 respectively. The volume of the proposed antenna is $113{\times}96.4{\times}3mm^3$. The metamaterial surface is used as a high impedance surface which shields the body from the hazards of electromagnetic radiations to reduce the Specific Absorption Rate (SAR). For on-body analysis a three layer model (containing skin, fats and muscles) of human arm is used. Antenna employing the EBG ground plane gives safe value of SAR (i.e. 1.77W/kg<2W/kg), when worn on human arm. This value is obtained using the safe limit of 2 W/kg, averaged over 10g of tissue, specified by the International Commission of Non Ionization Radiation Protection (ICNIRP). The SAR is reduced by 83.82 % as compare to the conventional antenna (8.16 W/kg>2W/kg). The efficiency of the EBG based antenna is improved from 52 to 74 %, relative to the conventional counterpart. The proposed antenna can be used in wearable electronics and smart clothing.

Intention to Quit Smoking among Intermediate and Secondary School Students in Saudi Arabia

  • Abdulmohsen Hamdan, Al-Zalabani;Ayat Roushdy, Abdallah;Reem Ibrahim, Alqabshawi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6741-6747
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    • 2015
  • Background: Smoking is one of the most preventable causes of disease and death, including cancer, and quitting at an early age can reduce smoking-related morbidity and mortality. This study aimed to estimate the prevalence and to identify factors affecting the "intention to quit" among intermediate and secondary school current cigarette smoker students in Al Madinah city, Saudi Arabia. Materials and Methods: This study cohort included 307 current smoker students in a school-based survey. The intention to quit and its related determinants were assessed using a self-administered questionnaire. Results: More than half of the participants were ${\geq}17$ years, and of male gender (54.7%, 77.9% respectively). An intention to quit smoking was reported in 71.7% of participants, and was been significantly associated with: male gender (OR=3.25, 95% CI=1.65-6.41): age at 1st trial of smoking. 10-15 years (OR=2.11, 95% CI=1.03-4.32) along with age of ${\geq}15$ years (OR=3.10, 95% CI=1.20-7.88); days of smoking in the past 30 days (days <10 (OR=2.31, 95% CI=1.23-4.35) along with days ranging from 10-19 days (OR= 3.42, 95% CI=1.18-9.91); knowing that smoking is hazardous to health (OR=3.04, 95% CI=1.42-6.47); and finally, supporting smoking bans in public places (OR=1.89, 95% CI=1.11-3.25). Conclusions: A substantial number of participants were willing to quit smoking. Effective interventions focusing on providing information about the hazards of smoking and prohibiting smoking in public places could help initiate the intention to quit among youth smokers.

Engineering characteristics of dune sand-fine marble waste mixtures

  • Qureshi, Mohsin U.;Mahmood, Zafar;Farooq, Qazi U.;Qureshi, Qadir B.I.L.;Al-Handasi, Hajar;Chang, Ilhan
    • Geomechanics and Engineering
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    • v.28 no.6
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    • pp.547-557
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    • 2022
  • Dune sands are poorly graded collapsible soils lacking fines. This experimental study explored the technical feasibility of sustainable invigoration of fine waste materials to improve the geotechnical properties of dune sand. The fine waste considered in this study is fine marble waste. The fine waste powder was mixed with dune sand at different contents (5, 10,15, 20, 25, 50%), where the gradation, void ratio, compaction, and shear strength characteristics were assessed for each fine marble waste -dune sand blend. The geotechnical properties of the dune sand-fine marble waste mix delineated in this study reveal the enhancement in compaction and gradation characteristics of dune sand. According to the results, the binary mixture of dune sand with 20% of fine marble waste gives the highest maximum dry density and results in shear strength improvement. In addition, a numerical study is conducted for the practical application of the binary mix in the field and tested for an isolated shallow foundation. The elemental analysis of the fine marble waste confirms that the material is non-contaminated and can be employed for engineering applications. Furthermore, the numerical study elucidated that the shallow surface replacement of the site with the dune sand mixed with 20% fine marble waste gives optimal performance in terms of stress generation and settlement behavior of an isolated footing. For a sustainable mechanical performance of the fine marble waste mixed sand, an optimum dose of 20% fine marble waste is recommended, and some correlations are proposed. Thus, for improving dune sand's geotechnical characteristics, the addition of fine marble waste to the dune sand is an environment-friendly solution.