• 제목/요약/키워드: Madecassol

검색결과 3건 처리시간 0.013초

아시아티코사이드로부터 메칠 2${\beta},\;3{\beta}$-에폭시-23- 히드록시우르스-12-엔-28-오애이트의 합성 및 이의 환원적 에폭시환 개열반응 (Formation of Methyl 2${\beta},\;3{\beta}$-Epoxy-23-hydroxyurs-12-en-28-oate from Asiaticoside and Its Reductive Epoxide Ring Opening Reaction)

  • 주상섭;임두연;서성기;남태규;박형근;김희두;김창민;이민희;백형근;이민정;정영훈
    • 약학회지
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    • 제42권5호
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    • pp.500-506
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    • 1998

  • Steroidal 2${\beta},\;3{\beta}$--epoxy compound was prepared from asiaticoside via six steps and reduced regioselectively with lithium aluminum hydride. Epoxide ring opening furnished 9 as a sole product at reflux condition through axial hydride attack at C-3.

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