• 한국안전학회지
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• 제10권3호
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• pp.42-46
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• 1995

To purpose of this study is to model design and motion analysis of tangential cam mechanism using personal computer system. The CAD(Computer Aided Design) system used in this study was constructed with CPU(Central Processing Unit) 80486, RAM(Random Access Memory) 8M, CGA graphic card. By using developed program for tangential cam mechanism, we designed tangential cam models and analysed displacement, velocity, acceleration of follower.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2007년도 추계학술대회 논문집
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• pp.357-358
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• 2007

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2007년도 추계학술대회 논문집
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• pp.397-398
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• 2007

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2007년도 춘계학술대회 논문집
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• pp.289-290
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• 2007

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2007년도 춘계학술대회 논문집
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• pp.505-506
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• 2007

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1299-1302
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• 2005

Current mechanical devices are trending toward being a small size, high speedy, automation. For performing these functions, machinery elements organizing a machine should be designed exactly. Cams have high confidence and economics in ablility to transmit a motion. Accordingly, A cam mechanism is very important for processing the machine automatically. This paper introduce an inverse cam mechanism. A square shaped cam which cannot be commonly analyzed is designed and manufactured by using the NURBS interpolation algorithm. The objective of this paper is to develop a computer-aided design program. In this paper, a displacement curve of oscillating motion inverse cam mechanism with square shaped follower is analyzed. The data is redistibuted by the NURBS algorithm. A cam shape is designed by the instant velocity center method, and simulated to verify the validity of the operation state.

• The Journal of Advanced Prosthodontics
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• 제9권5호
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• pp.402-408
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• 2017

PURPOSE. The goal of this study was to compare the adhesion of Candida albicans to the surfaces of CAD/CAM and conventionally fabricated complete denture bases. MATERIALS AND METHODS. Twenty discs of acrylic resin poly (methyl methacrylate) were fabricated with CAD/CAM and conventional procedures (heat-polymerized acrylic resin). The specimens were divided into two groups: 10 discs were fabricated using the CAD/CAM procedure (Wieland Digital Denture Ivoclar Vivadent), and 10 discs were fabricated using a conventional flasking and pressure-pack technique. Candida colonization was performed on all the specimens using four Candida albicans isolates. The difference in Candida albicans adhesion on the discs was evaluated. The number of adherent yeast cells was calculated by the colony-forming units (CFU) and by Fluorescence microscopy. RESULTS. There was a significant difference in the adhesion of Candida albicans to the complete denture bases created with CAD/CAM and the adhesion to those created with the conventional procedure. The CAD/CAM denture bases exhibited less adhesion of Candida albicans than did the denture bases created with the conventional procedure (P<.05). CONCLUSION. The CAD/CAM procedure for fabricating complete dentures showed promising potential for reducing the adherence of Candida to the denture base surface. Clinical Implications. Complete dentures made with the CAD/CAM procedure might decrease the incidence of denture stomatitis compared with conventional dentures.

• BMB Reports
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• 제41권11호
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• pp.771-777
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• 2008

Calmodulin (CaM) proteins, members of the EF-hand family of $Ca^{2+}$-binding proteins, represent important relays in plant calcium signals. Here, OsCam1-1 was isolated by PCR amplification from the rice genome. The gene contains an ORF of 450 base pairs with a single intron at the same position found in other plant Cam genes. A promoter region with a TATA box at position-26 was predicted and fused to a gus reporter gene, and this construct was used to produce transgenic rice by Agrobacterium-mediated transformation. GUS activity was observed in all organs examined and throughout tissues in cross-sections, but activity was strongest in the vascular bundles of leaves and the vascular cylinders of roots. To examine the properties of OsCaM1-1, the encoding cDNA was expressed in Escherichia coli. The electrophoretic mobility shift when incubated with $Ca^{2+}$ indicates that recombinant OsCaM1-1 is a functional $Ca^{2+}$-binding protein. In addition, OsCaM1-1 bound the CaMKII target peptide confirming its likely functionality as a calmodulin.

• 한국독성학회:학술대회논문집
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• 한국독성학회 1997년도 국제 심포지움 및 춘계 학술대회
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• pp.57-60
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• 1997

Aloe의 추출 시료들 중 혈관생성을 촉진하는 물질이 G1M1D1M1 분획에 있음을 chorioallantoic-membrane(CAM) assay, in vitro angiogenesis assay, u-PA, PAI, u-PAR, 및 matrix metalloprotease(MMP)의 유전자 발현조사, gelatin zymogram assay, modified CAM assay를 하여 확인 하였다. 그런 다음 G1M1D1M1 분획을 다시 분리하여 단일 성분인 NY932와 3종의 분획들을(U>3,000, 3,000>U>1,000, U<1,000) 얻었다. 이들 각각에 대한 혈관 생성 촉진 작용을 CAM assay 방법으로 조사한 결과 순수단일 성분인NY932가 혈관 생성 촉진 활성을 가장 높게 나타났다. 즉 NY932의 농도를 100ng, 2, 10, 35, 60 $\mu$g으로 투여하였을 때, 각각 2/18($11\%$), 4/10($49\%$), 16/22($73\%$), 15/17($88\%$), 9/9($100\%$)의 혈관생성 촉진 효과를 보였다. 따라서 순수 단일 성분인 NY932의 혈관 생성 촉진 작용기전을 규명하기 위하여 혈관 생성에 관련된 효소들[matrix metalloprotease(MMP)s, urokinase-plasminogen activator(uPA) 등]과 그 저해제들(TIMPs, PAI)의 유전자 발현을 조사하였으며, wounding migration assay등을 수행하였다.

• 대한치과보철학회지
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• 제44권3호
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• pp.275-283
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• 2006

Statement of problem. There have been many studies about marginal discrepancy of single restorations made by various systems and materials. However most of the statistical inferences are not definite because of sample size, measurement number, measuring instruments, etc, and there have been few studies about the marginal fit of the Digident CAD/ CAM zirconia ceramic crowns. Purpose. The purpose of this study was to compare the marginal fit of the anterior single restorations made by using the Digident CAD / CAM zirconia ceramic crowns with metal-ceramic restorations and to obtain more accurate information by using a large enough sample size and by making sufficient measurements per specimen. Material and Methods. The crowns were made from one extracted maxillary central incisor pre-pared with a 1mm shoulder margin and $6^{\circ}$ taper walls by milling machine. The in vitro marginal discrepancies of the digident CAD / CAM zirconia ceramic crowns and control groups(metal ceramic crowns) were evaluated and compared. Twenty crowns per each system were fabricated. Measurements of a crown were recorded at 50 points that were randomly selected for marginal gap evaluation. Parametric statistical analysis was performed for the results. Conclusion. Within the limitations of this in vitro study, the following conclusions were drawn: 1. Mean gap dimensions and standard deviations at the marginal opening for maxillary incisal crowns were $88{\pm}10{\mu}m$ for the control (metal-ceramic crowns), $92{\pm}4{\mu}m$ for Digident CAD / CAM zirconia ceramic crowns. 2. Marginal gap between Digident CAD / CAM zirconia ceramic crowns and metal ceramic crowns did not show significant difference (P>.05). 3. The Digident CAD/ CAM zirconia ceramic crowns and metal ceramic crowns showed clinically acceptable marginal discrepancy.