• Journal of Nutrition and Health
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• v.52 no.2
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• pp.139-148
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• 2019

Purpose: Ulcerative colitis is a common inflammatory bowel disease. Prolonged colitis can be a risk factor for the development of colorectal cancer. Mulberry twig (MT, Sangzhi), a dry branch of Morus alba L., which is widely distributed throughout East Asia, has been shown to have anti-inflammatory activities in the cells. However, the effects of MT extracts on colitis in in vivo are limited. Therefore, in this study, we investigated the anti-inflammatory effects of MT extracts in the dextran sulfate sodium (DSS)-induced mouse colitis model. Methods: Six week-old, male ICR mice were divided into 3 groups: Control (n = 5), DSS (n = 7), and DSS+MT (n = 7) groups. Mice in the DSS and DSS+MT groups were administrated 3% DSS in drinking water for 5 days to induce colitis. At the same time, water extracts of MT (5 g/kg body weight/day) were orally administered to mice in the DSS+MT groups for 5 days. Results: The MT extracts significantly reduced the clinical and pathological characteristics of colitis. Disease activity index, mucosal thickness, and colonocyte proliferation were significantly reduced in the DSS+MT group compared with the DSS group. Furthermore, MT administration reduced the levels of plasma $TNF-{\alpha}$, IL-6, and the colonic myeloperoxidase activity as well as mRNA expression of $TNF-{\alpha}$, IL-6, Cox-2, and iNOS. Conclusion: Taken together, these results suggest that MT water extracts have potent anti-colitis activities in the mouse colitis model.

• Geophysics and Geophysical Exploration
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• v.22 no.2
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• pp.62-71
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• 2019

We conducted DC resistivity and MT survey to obtain the resistivity structure of the central Myanmar basin. We tried to analyze the underground structure through the resistivity variation of Myanmar by performing representative geophysical survey methods because researches on the electrical resistivity structure are insufficient in Myanmar. The electrical resistivity is expected to be low considering the marine sedimentary rocks composed of shale and sandstone in this area. The DC resistivity and MT survey were carried out using SmartRho of Geolux Co., Ltd. and MTU-5A of Phoenix geophysics Ltd., respectively, to visualize the electrical resistivity structure of study area. DC resistivity and MT survey showed an electrical resistivity less than dozens of ohm-m within the depth of 100 m. In particular, MT survey data were almost similar to TM and TE modes in the frequency range above 1 Hz. The two-dimensional inversion of MT data showed a subsurface structure with low resistivity below 150 ohm-m divided into east-west direction. We confirmed that the inversions of DC resisitivity and MT data along an overlapped survey line represented similar results. In the future, considering the high electrical conductivity, it would be effective to perform DC resistivity and MT survey simultaneously to study the electrical resistivity structure of the central Myanmar basin.

• The Korean Journal of Ecology
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• v.9 no.1
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• pp.79-90
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• 1986

The production and decomposition of litters and nutrient cycling of forests were studied at the pine forests such as Pinus densiflora, Pinus koraiensis, Pinus rigida, Pinus thunbergii, Abies holophylla and Larix kaempfer. The annual litter production of the P. densiflora forest was the most on Mt. Mudeung which was 620.75g/$m^2$ and the least on Mt. Halla which was 155.00g/$m^2$. The decay rate of litters was the highest at the P. densiflora forest on Mt. Mudeung which was k=0.256 and the lowest at the P. densiflora forest on Mt. Halla and A. holophylla on Mt. Jiri which were k=0.099. The half time of decomposition of litters was shortest at the P. densiflora forest on Mt. Mudeung and the longest at the P. densiflora on Mt. Halla and A. holophylla forests on Mt. Jiri. The average decay rate of the L. kaempferi forests which was k=0.204 was the highest and that of the A. holophylla forests which was k=0.122 was the lowest. The decay rate tended to decrease against increasing the altitude. The annual production of litterr, the contents of mineral nutrients and the amounts of mineral nutrients inputted into the forest soil tended to increase in proportion to the decay rate, k.

• Animal Systematics, Evolution and Diversity
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• v.11 no.4
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• pp.469-477
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• 1995

Drosophila lacertosa and D. sordidula are members of the robusta species group in virilis section of Drosophila. The mtDNA of both species was analyzed, using 10 restriction endonucleases. The mtDNA genome size of D. lacertosa and D. sordidula was 15.7 kbp, altogether, and the numbers of mtDNA fragment were 26 and 32, respectively. Restriction cleavage map of mtDNA in these species was constructed. The patterns of cleavage map were very different between two species and it means that speciation was taken for a long time ago.

• The Korean Journal of Ecology
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• v.17 no.4
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• pp.443-452
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• 1994

A phytosociological study of the forest vegetation was carried out in Mt. Chongok and Mt. Tuta from June, 1992 to August, 1993. The forest vegetation was classified into 1 order, 2 alliances, 1 suballiance and 4 communities; Vaccinium hirtum v. koreanum-Quercus monogolica community, Carex humilis v. nana-Pinus densiflora community, Sasa borealis-Carapinus laxiflora community, Plectranthus inflexus-Quercus variabilis community. Actual vegetation map was drawn in 1:25,000 scale.

• BMB Reports
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• v.51 no.2
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• pp.65-72
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• 2018

The endothelial to mesenchymal transition (EndMT) is a newly recognized, fundamental biological process involved in development and tissue regeneration, as well as pathological processes such as the complications of diabetes, fibrosis and pulmonary arterial hypertension. The EndMT process is tightly controlled by diverse signaling networks, similar to the epithelial to mesenchymal transition. Accumulating evidence suggests that microRNAs (miRNAs) are key regulators of this network, with the capacity to target multiple messenger RNAs involved in the EndMT process as well as in the regulation of disease progression. Thus, it is highly important to understand the molecular basis of miRNA control of EndMT. This review highlights the current fund of knowledge regarding the known links between miRNAs and the EndMT process, with a focus on the mechanism that regulates associated signaling pathways and discusses the potential for the EndMT as a therapeutic target to treat many diseases.

• Journal of Aquaculture
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• v.18 no.3
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• pp.167-172
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• 2005

Sex reversal to a functional male of sevenband grouper $(41.0{\pm}1.3cm\;TL,\;1.4{\pm}0.1kg\;BW)$ was induced by $17{\alpha}-methyltestosterone\;(MT,\;0.5\sim2.0mg/kg\;BW)$ implantation from March 17 to May 12,2002. Gonad of control group was composed of genial cells and peri-nucleolus oocyte during the experimental period. Gonad of fish treated with 0.5 mg MT/kg BW had peri-nucleolus oocytes, spermatogonia, spermatids and spermatozoa at the late stages of spermatogenesis, while the fish group treated with 1.0 and 2.0 mg MT/kg BW contained spermatoza in the efferent duct. Sperm were obtained from the experimental groups treated with a dose of $1.0{\sim}2.0mg$ MT/kg BW. In the MT treated groups, testosterone and 11-ketotestosterone levels were higher than those in the control group during the $2{\sim}6$ weeks of the experimental period (P<0.05). $Estradiol-17{\beta}$ was detected from fish in the experimental fish.

• Geophysics and Geophysical Exploration
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• v.27 no.2
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• pp.129-143
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• 2024

In magnetotelluric (MT) surveys, small inhomogeneities near the surface cause a static shift in which apparent resistivities shift regardless of frequency. As the static shift in MT data leads to errors in subsurface structure interpretation, many studies have been conducted over the past few decades to mitigate or remove the distortions it caused. The most representative method involves removing static shifts from the data before inversion. Conversely, static shifts can be corrected during inversion or included in the inversion process. In addition, other geophysical data can be used to remove static shifts. However, the correction methods are limited to one-dimensional (1D) static responses, and limitations remain in two- or three-dimensional (2D or 3D) interpretation of distorted MT data owing to static shifts. This study provides a foundation for future studies on static shift by analyzing several previously published methods.

• The Korean Journal of Ecology
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• v.10 no.3
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• pp.109-118
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• 1987

The production and decomposition rates of litters were studied in three mountains, Mt. Halla, Mt. So-back and Mt. Tae-back. The amounts of N, P, K, Ca and Na in the soils were measured and the relationships between the mineral nutrients and decay rates were reserched, The annual litter production was the most as $1, 077.3g/m^2$ and the least as $248.0g/m^2$ in a stand of Quercus acutissima at 820m of the Mt. So-back and at 1, 350m of the Mt. So-back among the study sites, respectively. The decay rates of litter was the highest as k=0.448 and the lowest as k=0.082 in a stand of Q. acutissima at 820m of the Mt. So-back and at 1, 450m of the Mt. Tae-back at 1, 450m of the Mt. Tae-back among the study sites. The higher altitude was, the slower the decay rates were. The annual contents of mineral nutrient and their amounts inputted into the forest soil were proportional to the decay rate of organic metters.

• Journal of Yeungnam Medical Science
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• v.36 no.2
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• pp.92-98
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• 2019

Forefoot disorders are often seen in clinical practice. Forefoot deformity and pain can deteriorate gait function and decrease quality of life. This review presents common forefoot disorders and conservative treatment using an insole or orthosis. Metatarsalgia is a painful foot condition affecting the metatarsal (MT) region of the foot. A MT pad, MT bar, or forefoot cushion can be used to alleviate MT pain. Hallux valgus is a deformity characterized by medial deviation of the first MT and lateral deviation of the hallux. A toe spreader, valgus splint, and bunion shield are commonly applied to patients with hallux valgus. Hallux limitus and hallux rigidus refer to painful limitations of dorsiflexion of the first metatarsophalangeal joint. A kinetic wedge foot orthosis or rocker sole can help relieve symptoms from hallux limitus or rigidus. Hammer, claw, and mallet toes are sagittal plane deformities of the lesser toes. Toe sleeve or padding can be applied over high-pressure areas in the proximal or distal interphalangeal joints or under the MT heads. An MT off-loading insole can also be used to alleviate symptoms following lesser toe deformities. Morton's neuroma is a benign neuroma of an intermetatarsal plantar nerve that leads to a painful condition affecting the MT area. The MT bar, the plantar pad, or a more cushioned insole would be useful. In addition, patients with any of the above various forefoot disorders should avoid tight-fitting or high-heeled shoes. Applying an insole or orthosis and wearing proper shoes can be beneficial for managing forefoot disorders.