• Genomics & Informatics
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• v.16 no.4
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• pp.31.1-31.7
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• 2018

The prevalence of metabolic syndrome (MS) in the nonobese population is not low. However, the identification and risk mitigation of MS are not easy in this population. We aimed to develop an MS prediction model using genetic and clinical factors of nonobese Koreans through machine learning methods. A prediction model for MS was designed for a nonobese population using clinical and genetic polymorphism information with five machine learning algorithms, including naïve Bayes classification (NB). The analysis was performed in two stages (training and test sets). Model A was designed with only clinical information (age, sex, body mass index, smoking status, alcohol consumption status, and exercise status), and for model B, genetic information (for 10 polymorphisms) was added to model A. Of the 7,502 nonobese participants, 647 (8.6%) had MS. In the test set analysis, for the maximum sensitivity criterion, NB showed the highest sensitivity: 0.38 for model A and 0.42 for model B. The specificity of NB was 0.79 for model A and 0.80 for model B. In a comparison of the performances of models A and B by NB, model B (area under the receiver operating characteristic curve [AUC] = 0.69, clinical and genetic information input) showed better performance than model A (AUC = 0.65, clinical information only input). We designed a prediction model for MS in a nonobese population using clinical and genetic information. With this model, we might convince nonobese MS individuals to undergo health checks and adopt behaviors associated with a preventive lifestyle.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.8
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• pp.1143-1149
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• 2017

Objective: The objective of the present study was to determine whether mango saponin (MS) could be used as a feed additive in broiler chicks by evaluating growth performance, carcass characteristics, meat quality, and plasma biochemical indices. Methods: A total of 216 1-d-old Arbor Acres male broiler chicks were randomly assigned into three dietary treatments supplemented with 0 (control), 0.14% (MS 0.14%), or 0.28% (MS 0.28%) MS. Each treatment had six replicates (cages) with 12 chicks each. The feeding trial lasted for six weeks. Results: Compared with the control, dietary supplemented with 0.14% or 0.28% MS increased average daily weight gain of chicks in the grower (22 to 42 d) and the whole (1 to 42 d) phases, and the final body weight of chicks on d 42 was higher in MS supplemented groups (p<0.05). Lower $L_{45min}{^{\star}}$ (lightness) and $L_{24h}{^{\star}}$ values, lower $b_{24h}{^{\star}}$ (yellowness) value, and higher $a_{45min}{^{\star}}$ (redness) and $a_{24h}{^{\star}}$ values of the breast muscle were observed in chicks fed with 0.28% MS on d 42 (p<0.05). The total antioxidant capacity in plasma increased in MS 0.14% group on d 21 (p<0.001). Lower contents of plasma total cholesterol and triglyceride were observed in chicks fed with 0.28% MS on d 21 and d 42, whereas the group supplemented with 0.14% MS only decreased plasma triglyceride content on d 21 (p<0.05). The glucose content in plasma decreased in MS 0.28% group on d 42 (p<0.001). Conclusion: Overall, MS could be used as a feed additive in broiler chicks, and the supplemental level of 0.28% MS in diet could improve growth performance, meat quality, and plasma lipid metabolism in broiler chicks.

• Journal of the Korean Applied Science and Technology
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• v.35 no.4
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• pp.1260-1268
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• 2018

To improve fuel performance and specific characteristics of long storage and moving through fuel systems additives should be added in kerosene type aviation turbine fuel (AVTUR) such as antioxidant, fuel system icing inhibitor (FSII), electric conductivity improvers and so on. The dosage of additives has to be analyzed qualitatively and quantitatively due to inspect the quality of abnormal fuel and distinguish other petroleum products. Multi-dimensional GC-MS (MDGC-MS) with Deans switching technique are applied the determination of antioxidant and FSII, which are added with AVTUR containing complex mixture of hydrocarbons. Antioxidant and FSII in the range of 2.5-20 mg/L was quantitatively and qualitatively analyzed using MDGC-MS and the detection limit was about twice as low as that of the 1-dimensional GC-MS results. The method in this study has been higher peak resolution compared with GC-MS and could be simultaneously analyzed different two additives without sample pre-treatment.

• Korean Journal of Ichthyology
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• v.35 no.2
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• pp.67-74
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• 2023

The river pufferfish (Takifugu obscurus) is a valuable species in aquaculture and genetic studies. Usage of fish anesthetics aids in the easier handling of fish during aquaculture. However, there are no studies on appropriate conditions required for effective anesthetization of pufferfish. This study aims to determine the optimal conditions (fish age, water temperature, anesthetic concentration) needed for the most common fish anesthesia, MS-222, to anesthetize T. obscurus. We tested three different water temperatures (20℃, 24℃, and 28℃), three different anesthetic concentrations (125 mg/L, 150 mg/L, and 175 mg/L), and two different fish ages (one- and two-year-old). Appropriate anesthetization conditions for T. obscurus ranged from 150 mg/L to 175 mg/L of MS-222 at 24℃ to 28℃ for one-year-old fish. For two-year-old fish, the appropriate conditions ranged from 150 mg/L to 175 mg/L of MS-222 at 28℃. However, to minimize side effects and risks, 150 mg/L of MS-222 at 24℃ for one-year-old fish and 175 mg/L of MS-222 at 28℃ for two-year-old fish are recommended for effective anesthetization.

• Bulletin of the Korean Chemical Society
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• v.29 no.9
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• pp.1847-1849
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• 2008

• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.10
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• pp.1385-1391
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• 2010

In this study, we present small-size, low-power, and high-speed electromagnetic flapping shutters for phone cameras. These shutters are composed of trapezoidal twin blades suspended by H-type torsional springs. The existing electrostatic rolling and flapping shutters need high input voltage, while the existing electromagnetic rotating shutters are too big to be used for phone cameras. To achieve low-power and high-speed angle motion for small-size electromagnetic flapping shutters for camera phones, low-inertia trapezoidal twin blades, each suspended by the low-stiffness H-type torsional springs, are employed. The electromagnetic flapping shutters used in this experimental study have steady-state rotational angles of $48.8{\pm}1.4^{\circ}$ and $64.4{\pm}1.0^{\circ}$ in the magentic fields of 0.15 T and 0.30 T, respectively, for an input current of 60 mA; the maximum overshoot angles are $80.2{\pm}3.5^{\circ}$ and $90.0{\pm}1.0^{\circ}$ in the magentic fields of 0.15 T and 0.30 T, respectively. The rising/settling times of the shutter while opening are 1.0 ms/20.0 ms, while those while closing are 1.7 ms/10.3 ms. Thus, we experimentally demonstrated that the smallsize (${\sim}8{\times}8{\times}2\;mm^3$), low-power (${\leq}60\;mA$), and high-speed (~1/370 s) electromagnetic flapping shutters are suitable for phone cameras.

• Korean Journal of Agricultural Science
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• v.43 no.4
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• pp.634-640
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• 2016

The objective of this study was to evaluate the effectiveness of using HR-GC/MS for the rapid screening of dieldrin residues in soils. Persistent organic pollutants (POPs) of organochlorine pesticides such as dieldrin, were analyzed in sedimentary rock and granite rock collected from greenhouses, Niigata, Japan. Dieldrin remains in Japanese farming soils, more than 40 years after their use as insecticides was prohibited. The averages in soil moisture ranged from 2.79% to 7.20% in soils derived from sedimentary rock and from 25.59% to 31.40% in soils derived from granite rock. Mean concentrations of dieldrin residues in sedimentary rock and granite rock were $39.7ng\;g^{-1}$ and $40.51ng\;g^{-1}$, respectively. Dieldrin residue was detected at a slightly higher concentration in granite rock than sedimentary rock samples. There was no consistency between the two soils or between surface and subsurface soils. The coefficients of variation of the two soils were 10.6% and 8.7%, respectively. These results suggest that our high-resolution mass spectrometry detector (HR-GC/MS) is effective at analyzing residual organochlorine pesticides in soil. In order to increase the precision and sensitivity for chemical analysis of POPs, high-resolution gas chromatography coupled with a HR-GC/MS is highly recommended.

• Bulletin of the Korean Chemical Society
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• v.32 no.2
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• pp.524-530
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• 2011

In the present study, we demonstrate that SRM LC-MS/MS method developed by Luo et al. (ref. 10) can be successfully applied to the quantitative analysis of intracellular metabolites in E. coli that are collected at the exponential and stationary growth phases. A focus is given on measuring the changes in the concentrations of intracellular metabolites in batch cultures, which were induced during both the dynamically changing exponential and stationary growth phases. The following intracellular metabolites are quantified in the exponential and stationary phases of E. coli growth, using the SRM mode of a triple quadrupole mass spectrometer: glucose-1-phosphate, fructose-1,6-bisphosphate, phosphoenolpyruvate, pyruvate, acetyl-coenzyme A, 6-phosphogluconate, ribulose-5-phosphate, xylulose-5-phosphate, erythrose-4-phosphate. The determined intracellular metabolite concentration profiles are shown to be in a good agreement with the growth profiles of E. coli, which clearly indicates that SRM LC-MS/MS can be successfully used for following the metabolite changes induced at different growth stages.

• Explosives and Blasting
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• v.22 no.2
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• pp.1-11
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• 2004

일반적으로 국내 석회석 광산에서의 발파는 20ms나 25ms 시차를 가지는 지발발파로 시행되어지고 있다. 국외에서는 전자뇌관을 사용하여 암반의 지질학적인 특성에 따라 지발 시차를 사용자의 현장에 따라 선정하여, 주변 보안 물건에 따른 진동 및 소음을 경감하면서, 1회 발파의 생산량을 증대할 수 있으며, 2차 파쇄 비용 및 적재비용을 절감하는 최적의 시차를 적용하여 발파 규모를 줄이지 않는 발파패턴을 적용하고 있다. 본 연구는 해외에서 사용되고 있는 전자뇌관을 국내 현장 석회석 광산(단양)에 적용함으로 최적지연시차를 찾아내는 방법과 초시의 오차에 따른 문제점과 향후 국내 적용성을 판단하고자 하였다. 대규모 석회석 광산을 대상으로 최적시차를 판단하고자 동일 패턴에서 시차를 6ms ~ 30ms로 시험발파를 시행하여 4가지 요소 발파진동속도, 주 주파수특성, 파쇄입도, 암석 이동 및 버력의 상태를 분석하여 각 시차에 따른 배점을 두어, 당 현장에 요구되는 개별 가중치를 선정하여 분석하였다. 분석 결과 당 현장에서의 발파결과에 따른 요소별 가중치를 발파진동속도(20), 주 주파수 특성(20), 파쇄입도(40), 암석 이동(10) 및 버력의 상태(10)로 하여 분석한 결과 15ms가 최적시차로 나타냈다. 향후 각 현장에 적합한 요소별 가중치를 선정하여 현장별 최적시차를 도출한다면 최적의 발파효과를 있을 것으로 판단된다.

• The Journal of the Korea institute of electronic communication sciences
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• v.5 no.3
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• pp.251-255
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• 2010

In this study, the effects leading and following tone with single frequency on sound lateralization were investigated. The tone with level difference and ISI(Inter Stimuli Interval) were used. The width of test tone was 2ms, leading tone and following tone were 10ms and 1kHz was used. The arrived time difference of subject's ears 0.5ms. We set four levels on each ISI and let them decide whether they hear the provided sound from left or right. As a result, it knew the fact that leading tone had more effect on sound lateralization than following tone.